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Ovarian Wolffian Tumor

MedGen UID:
1792201
•Concept ID:
C5555760
•
Neoplastic Process
Synonym: Wolffian Tumor of the Ovary

Definition

An epithelial neoplasm of Wolffian (mesonephric) origin arising from the ovarian hilum. Most tumors behave in a benign fashion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOvarian Wolffian Tumor

Recent clinical studies

Diagnosis

Cytohistopathologic correlation of ovarian mesonephric-like carcinoma and female adnexal tumor of probable Wolffian origin.
Qazi M, Movahedi-Lankarani S, Wang BG
Diagn Cytopathol 2021 Jun;49(6):E207-E213. Epub 2020 Dec 9 doi: 10.1002/dc.24675. PMID: 33296554
Female adnexal tumors of probable Wolffian origin: morphological, immunohistochemical, and molecular analysis of 15 cases.
Bennett JA, Ritterhouse LL, Furtado LV, Lastra RR, Pesci A, Newell JM, Burandt E, Kooreman L, Van de Vijver K, Krausz T, Felix A, Zannoni GF, Young RH, Oliva E
Mod Pathol 2020 Apr;33(4):734-747. Epub 2019 Oct 7 doi: 10.1038/s41379-019-0375-9. PMID: 31591497
Malignant Female Adnexal Tumor of Probable Wolffian Origin: Case Report and Literature Review.
Hong S, Cui J, Li L, Buscema J, Liggins C, Zheng W
Int J Gynecol Pathol 2018 Jul;37(4):331-337. doi: 10.1097/PGP.0000000000000422. PMID: 28700436
Value of PAX-8 and SF-1 Immunohistochemistry in the Distinction Between Female Adnexal Tumor of Probable Wolffian Origin and its Mimics.
Goyal A, Masand RP, Roma AA
Int J Gynecol Pathol 2016 Mar;35(2):167-75. doi: 10.1097/PGP.0000000000000222. PMID: 26352548
Endometrioid carcinoma with a low-grade spindle cell component: a tumor resembling an adnexal tumor of probable Wolffian origin.
Tipps AM, Plaxe SC, Weidner N
Ann Diagn Pathol 2011 Oct;15(5):376-81. Epub 2010 Oct 12 doi: 10.1016/j.anndiagpath.2010.06.004. PMID: 20952275

Therapy

Female adnexal tumor of probable Wolffian origin (FATWO) with recurrence 3 years postsurgery.
Syriac S, Durie N, Kesterson J, Lele S, Mhawech-Fauceglia P
Int J Gynecol Pathol 2011 May;30(3):231-5. doi: 10.1097/PGP.0b013e3182005340. PMID: 21464731Free PMC Article

Prognosis

Female adnexal tumors of probable Wolffian origin: morphological, immunohistochemical, and molecular analysis of 15 cases.
Bennett JA, Ritterhouse LL, Furtado LV, Lastra RR, Pesci A, Newell JM, Burandt E, Kooreman L, Van de Vijver K, Krausz T, Felix A, Zannoni GF, Young RH, Oliva E
Mod Pathol 2020 Apr;33(4):734-747. Epub 2019 Oct 7 doi: 10.1038/s41379-019-0375-9. PMID: 31591497
Female adnexal tumor of probable Wolffian origin (FATWO) with recurrence 3 years postsurgery.
Syriac S, Durie N, Kesterson J, Lele S, Mhawech-Fauceglia P
Int J Gynecol Pathol 2011 May;30(3):231-5. doi: 10.1097/PGP.0b013e3182005340. PMID: 21464731Free PMC Article
Endometrioid carcinoma with a low-grade spindle cell component: a tumor resembling an adnexal tumor of probable Wolffian origin.
Tipps AM, Plaxe SC, Weidner N
Ann Diagn Pathol 2011 Oct;15(5):376-81. Epub 2010 Oct 12 doi: 10.1016/j.anndiagpath.2010.06.004. PMID: 20952275

Clinical prediction guides

Female adnexal tumors of probable Wolffian origin: morphological, immunohistochemical, and molecular analysis of 15 cases.
Bennett JA, Ritterhouse LL, Furtado LV, Lastra RR, Pesci A, Newell JM, Burandt E, Kooreman L, Van de Vijver K, Krausz T, Felix A, Zannoni GF, Young RH, Oliva E
Mod Pathol 2020 Apr;33(4):734-747. Epub 2019 Oct 7 doi: 10.1038/s41379-019-0375-9. PMID: 31591497

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