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Metastatic Malignant Neoplasm in the Breast

MedGen UID:
1787931
Concept ID:
C5441655
Neoplastic Process
Synonyms: Breast Metastases; Breast Metastasis; Metastatic Cancer to the Breast; Metastatic malignant neoplasm of breast; Metastatic malignant neoplasm to breast; Metastatic Malignant Neoplasm to the Breast; Metastatic Neoplasm to the Breast; Metastatic Tumor to the Breast; Secondary malignant neoplasm of breast
SNOMED CT: Secondary malignant neoplasm of breast (145501000119108); Metastatic malignant neoplasm of breast (145501000119108); Metastatic malignant neoplasm to breast (145501000119108)

Definition

The spread of a malignant neoplasm to the breast. This may be from a primary breast malignant neoplasm on the opposite side, or from a malignant neoplasm at a distant site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Malignant Neoplasm in the Breast

Professional guidelines

PubMed

Cardoso F, Paluch-Shimon S, Schumacher-Wulf E, Matos L, Gelmon K, Aapro MS, Bajpai J, Barrios CH, Bergh J, Bergsten-Nordström E, Biganzoli L, Cardoso MJ, Carey LA, Chavez-MacGregor M, Chidebe R, Cortés J, Curigliano G, Dent RA, El Saghir NS, Eniu A, Fallowfield L, Francis PA, Franco Millan SX, Gilchrist J, Gligorov J, Gradishar WJ, Haidinger R, Harbeck N, Hu X, Kaur R, Kiely B, Kim SB, Koppikar S, Kuper-Hommel MJJ, Lecouvet FE, Mason G, Mertz SA, Mueller V, Myerson C, Neciosup S, Offersen BV, Ohno S, Pagani O, Partridge AH, Penault-Llorca F, Prat A, Rugo HS, Senkus E, Sledge GW, Swain SM, Thomssen C, Vorobiof DA, Vuylsteke P, Wiseman T, Xu B, Costa A, Norton L, Winer EP
Breast 2024 Aug;76:103756. Epub 2024 May 28 doi: 10.1016/j.breast.2024.103756. PMID: 38896983Free PMC Article
Zajączkowska R, Kocot-Kępska M, Leppert W, Wordliczek J
Int J Mol Sci 2019 Nov 30;20(23) doi: 10.3390/ijms20236047. PMID: 31801267Free PMC Article
Senkus E, Łacko A
Breast 2017 Feb;31:309-317. Epub 2016 Jul 21 doi: 10.1016/j.breast.2016.06.024. PMID: 27453572

Recent clinical studies

Etiology

Di Maio M, Bighin C, Schettini F, Ruelle T, Marandino L, Fabi A, De Angelis C, Giuliano M, De Placido P, De Laurentiis M, Riccardi F, Picotto C, Puglisi F, Del Mastro L, Arpino G; Gruppo Italiano Mammella (GIM) Study Group
Breast 2023 Dec;72:103583. Epub 2023 Sep 25 doi: 10.1016/j.breast.2023.103583. PMID: 37783133Free PMC Article
Goodwin B, Oyinlola AF, Palhang M, Lehman D, Platoff R, Atabek U, Spitz F, Hong Y
Am Surg 2023 Dec;89(12):6190-6196. Epub 2023 Aug 23 doi: 10.1177/00031348231198114. PMID: 37611540
van Ommen-Nijhof A, Steenbruggen TG, Capel L, Vergouwen M, Vrancken Peeters MT, Wiersma TG, Sonke GS
Breast 2023 Feb;67:14-20. Epub 2022 Dec 14 doi: 10.1016/j.breast.2022.12.007. PMID: 36549169Free PMC Article
Zhou P, Chang N, Abraham SC, Albarracin CT, Huo L, Chen H, Ding Q, Resetkova E, Middleton LP, Sahin AA, Bu H, Wu Y
Hum Pathol 2022 Jul;125:59-67. Epub 2022 Apr 18 doi: 10.1016/j.humpath.2022.04.009. PMID: 35447141
Prat A, Pineda E, Adamo B, Galván P, Fernández A, Gaba L, Díez M, Viladot M, Arance A, Muñoz M
Breast 2015 Nov;24 Suppl 2:S26-35. Epub 2015 Aug 5 doi: 10.1016/j.breast.2015.07.008. PMID: 26253814

Diagnosis

Cardoso F, Paluch-Shimon S, Schumacher-Wulf E, Matos L, Gelmon K, Aapro MS, Bajpai J, Barrios CH, Bergh J, Bergsten-Nordström E, Biganzoli L, Cardoso MJ, Carey LA, Chavez-MacGregor M, Chidebe R, Cortés J, Curigliano G, Dent RA, El Saghir NS, Eniu A, Fallowfield L, Francis PA, Franco Millan SX, Gilchrist J, Gligorov J, Gradishar WJ, Haidinger R, Harbeck N, Hu X, Kaur R, Kiely B, Kim SB, Koppikar S, Kuper-Hommel MJJ, Lecouvet FE, Mason G, Mertz SA, Mueller V, Myerson C, Neciosup S, Offersen BV, Ohno S, Pagani O, Partridge AH, Penault-Llorca F, Prat A, Rugo HS, Senkus E, Sledge GW, Swain SM, Thomssen C, Vorobiof DA, Vuylsteke P, Wiseman T, Xu B, Costa A, Norton L, Winer EP
Breast 2024 Aug;76:103756. Epub 2024 May 28 doi: 10.1016/j.breast.2024.103756. PMID: 38896983Free PMC Article
Goodwin B, Oyinlola AF, Palhang M, Lehman D, Platoff R, Atabek U, Spitz F, Hong Y
Am Surg 2023 Dec;89(12):6190-6196. Epub 2023 Aug 23 doi: 10.1177/00031348231198114. PMID: 37611540
Ofri A, Moore K
Breast 2020 Dec;54:211-215. Epub 2020 Oct 27 doi: 10.1016/j.breast.2020.10.012. PMID: 33130487Free PMC Article
Kenny LM, Orsi F, Adam A
Breast 2017 Oct;35:98-103. Epub 2017 Jul 10 doi: 10.1016/j.breast.2017.06.012. PMID: 28704698
Lloyd MS, Nash AG
Ann R Coll Surg Engl 2001 Nov;83(6):420-4. PMID: 11777139Free PMC Article

Therapy

Corti C, Boscolo Bielo L, Schianca AC, Salimbeni BT, Criscitiello C, Curigliano G
Breast 2023 Jun;69:312-322. Epub 2023 Mar 24 doi: 10.1016/j.breast.2023.03.007. PMID: 36996620Free PMC Article
Shastry M, Jacob S, Rugo HS, Hamilton E
Breast 2022 Dec;66:169-177. Epub 2022 Oct 18 doi: 10.1016/j.breast.2022.10.007. PMID: 36302269Free PMC Article
Senkus E, Łacko A
Breast 2017 Feb;31:309-317. Epub 2016 Jul 21 doi: 10.1016/j.breast.2016.06.024. PMID: 27453572
Badwe R, Hawaldar R, Nair N, Kaushik R, Parmar V, Siddique S, Budrukkar A, Mittra I, Gupta S
Lancet Oncol 2015 Oct;16(13):1380-8. Epub 2015 Sep 9 doi: 10.1016/S1470-2045(15)00135-7. PMID: 26363985
Prat A, Pineda E, Adamo B, Galván P, Fernández A, Gaba L, Díez M, Viladot M, Arance A, Muñoz M
Breast 2015 Nov;24 Suppl 2:S26-35. Epub 2015 Aug 5 doi: 10.1016/j.breast.2015.07.008. PMID: 26253814

Prognosis

van Ommen-Nijhof A, Steenbruggen TG, Capel L, Vergouwen M, Vrancken Peeters MT, Wiersma TG, Sonke GS
Breast 2023 Feb;67:14-20. Epub 2022 Dec 14 doi: 10.1016/j.breast.2022.12.007. PMID: 36549169Free PMC Article
Possanzini M, Greco C
Breast 2018 Oct;41:57-66. Epub 2018 Jun 28 doi: 10.1016/j.breast.2018.06.011. PMID: 30007269
Peart O
Radiol Technol 2017 May;88(5):519M-539M. PMID: 28500107
Prat A, Pineda E, Adamo B, Galván P, Fernández A, Gaba L, Díez M, Viladot M, Arance A, Muñoz M
Breast 2015 Nov;24 Suppl 2:S26-35. Epub 2015 Aug 5 doi: 10.1016/j.breast.2015.07.008. PMID: 26253814
Arpino G, Milano M, De Placido S
Breast 2015 Oct;24(5):594-600. Epub 2015 Jul 3 doi: 10.1016/j.breast.2015.06.001. PMID: 26144637

Clinical prediction guides

Özşen M, Tolunay S, Polatkan SAV, Senol K, Gokgoz MS
Int J Surg Pathol 2024 Aug;32(5):875-883. Epub 2023 Oct 29 doi: 10.1177/10668969231201415. PMID: 37899598Free PMC Article
Krings G, Bean GR, Chen YY
Semin Diagn Pathol 2017 Sep;34(5):438-452. Epub 2017 May 28 doi: 10.1053/j.semdp.2017.05.006. PMID: 28688536
Hoffmann J, Ohgami RS
Semin Diagn Pathol 2017 Sep;34(5):462-469. Epub 2017 May 28 doi: 10.1053/j.semdp.2017.05.007. PMID: 28662998
Prat A, Pineda E, Adamo B, Galván P, Fernández A, Gaba L, Díez M, Viladot M, Arance A, Muñoz M
Breast 2015 Nov;24 Suppl 2:S26-35. Epub 2015 Aug 5 doi: 10.1016/j.breast.2015.07.008. PMID: 26253814
Miettinen M, McCue PA, Sarlomo-Rikala M, Rys J, Czapiewski P, Wazny K, Langfort R, Waloszczyk P, Biernat W, Lasota J, Wang Z
Am J Surg Pathol 2014 Jan;38(1):13-22. doi: 10.1097/PAS.0b013e3182a0218f. PMID: 24145643Free PMC Article

Recent systematic reviews

Goodwin B, Oyinlola AF, Palhang M, Lehman D, Platoff R, Atabek U, Spitz F, Hong Y
Am Surg 2023 Dec;89(12):6190-6196. Epub 2023 Aug 23 doi: 10.1177/00031348231198114. PMID: 37611540
Huin M, Body G, Arbion F, Ouldamer L
J Gynecol Obstet Hum Reprod 2022 Dec;51(10):102481. Epub 2022 Oct 5 doi: 10.1016/j.jogoh.2022.102481. PMID: 36208828
Nanda A, Hu J, Hodgkinson S, Ali S, Rainsbury R, Roy PG
Cochrane Database Syst Rev 2021 Oct 29;10(10):CD013658. doi: 10.1002/14651858.CD013658.pub2. PMID: 34713449Free PMC Article
Schettini F, Pascual T, Conte B, Chic N, Brasó-Maristany F, Galván P, Martínez O, Adamo B, Vidal M, Muñoz M, Fernández-Martinez A, Rognoni C, Griguolo G, Guarneri V, Conte PF, Locci M, Brase JC, Gonzalez-Farre B, Villagrasa P, De Placido S, Schiff R, Veeraraghavan J, Rimawi MF, Osborne CK, Pernas S, Perou CM, Carey LA, Prat A
Cancer Treat Rev 2020 Mar;84:101965. Epub 2020 Jan 17 doi: 10.1016/j.ctrv.2020.101965. PMID: 32000054Free PMC Article
Nielsen SM, White MG, Hong S, Aschebrook-Kilfoy B, Kaplan EL, Angelos P, Kulkarni SA, Olopade OI, Grogan RH
Cancer Epidemiol Biomarkers Prev 2016 Feb;25(2):231-8. doi: 10.1158/1055-9965.EPI-15-0833. PMID: 26908594Free PMC Article

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