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EEG with temporal epileptiform discharges

MedGen UID:
1785327
•Concept ID:
C5539776
•
Finding
HPO: HP:0033717

Definition

Focal epileptiform EEG discharges recorded in the temporal region. [from HPO]

Professional guidelines

PubMed

Relationship Between Aggravation of Seizures and Methylphenidate Treatment in Subjects with Attention-Deficit/Hyperactivity Disorder and Epilepsy.
Park J, Choi HW, Yum MS, Ko TS, Shon SH, Kim HW
J Child Adolesc Psychopharmacol 2018 Oct;28(8):537-546. Epub 2018 Aug 8 doi: 10.1089/cap.2017.0070. PMID: 30089215
Clinical characteristics and treatment responses in new-onset epilepsy in the elderly.
Tanaka A, Akamatsu N, Shouzaki T, Toyota T, Yamano M, Nakagawa M, Tsuji S
Seizure 2013 Nov;22(9):772-5. Epub 2013 Jul 10 doi: 10.1016/j.seizure.2013.06.005. PMID: 23849689
Analysis of EEG patterns and genotypes in patients with Angelman syndrome.
Vendrame M, Loddenkemper T, Zarowski M, Gregas M, Shuhaiber H, Sarco DP, Morales A, Nespeca M, Sharpe C, Haas K, Barnes G, Glaze D, Kothare SV
Epilepsy Behav 2012 Mar;23(3):261-5. Epub 2012 Feb 16 doi: 10.1016/j.yebeh.2011.11.027. PMID: 22341959

Recent clinical studies

Etiology

Subclinical epileptiform discharges in Alzheimer's disease are associated with increased hippocampal blood flow.
Musaeus CS, Kjaer TW, Lindberg U, Vestergaard MB, Bo H, Larsson W, Press DZ, Andersen BB, Høgh P, Kidmose P, Hemmsen MC, Rank ML, Hasselbalch SG, Waldemar G, Frederiksen KS
Alzheimers Res Ther 2024 Apr 12;16(1):80. doi: 10.1186/s13195-024-01432-9. PMID: 38610005Free PMC Article
Altered Sleep Microarchitecture and Cognitive Impairment in Patients With Temporal Lobe Epilepsy.
Bender AC, Jaleel A, Pellerin KR, Moguilner S, Sarkis RA, Cash SS, Lam AD
Neurology 2023 Dec 4;101(23):e2376-e2387. doi: 10.1212/WNL.0000000000207942. PMID: 37848332Free PMC Article
Epilepsy and EEG Abnormalities in Children with Autism Spectrum Disorders.
Sharma V, Saini AG, Malhi P, Singhi P
Indian J Pediatr 2022 Oct;89(10):975-982. Epub 2021 Nov 29 doi: 10.1007/s12098-021-03928-w. PMID: 34843062
A reliable interictal EEG grading scale for children with infantile spasms - The 2021 BASED score.
Mytinger JR, Vidaurre J, Moore-Clingenpeel M, Stanek JR, Albert DVF
Epilepsy Res 2021 Jul;173:106631. Epub 2021 Apr 2 doi: 10.1016/j.eplepsyres.2021.106631. PMID: 33839516
Mesial temporal lobe epilepsy.
Tatum WO 4th
J Clin Neurophysiol 2012 Oct;29(5):356-65. doi: 10.1097/WNP.0b013e31826b3ab7. PMID: 23027091

Diagnosis

A reliable interictal EEG grading scale for children with infantile spasms - The 2021 BASED score.
Mytinger JR, Vidaurre J, Moore-Clingenpeel M, Stanek JR, Albert DVF
Epilepsy Res 2021 Jul;173:106631. Epub 2021 Apr 2 doi: 10.1016/j.eplepsyres.2021.106631. PMID: 33839516
Recognition of interictal and ictal discharges on EEG. Focal vs generalized epilepsy.
Andrade-Machado R, Benjumea Cuartas V, Muhammad IK
Epilepsy Behav 2021 Apr;117:107830. Epub 2021 Feb 25 doi: 10.1016/j.yebeh.2021.107830. PMID: 33639439
Normal "suspicious" EEG.
Tatum WO
Neurology 2013 Jan 1;80(1 Suppl 1):S4-11. doi: 10.1212/WNL.0b013e31827974df. PMID: 23267043
Mesial temporal lobe epilepsy.
Tatum WO 4th
J Clin Neurophysiol 2012 Oct;29(5):356-65. doi: 10.1097/WNP.0b013e31826b3ab7. PMID: 23027091
Frontal lobe epilepsy.
Kellinghaus C, Lüders HO
Epileptic Disord 2004 Dec;6(4):223-39. PMID: 15634619

Therapy

Multisensory flicker modulates widespread brain networks and reduces interictal epileptiform discharges.
Blanpain LT, Cole ER, Chen E, Park JK, Walelign MY, Gross RE, Cabaniss BT, Willie JT, Singer AC
Nat Commun 2024 Apr 11;15(1):3156. doi: 10.1038/s41467-024-47263-y. PMID: 38605017Free PMC Article
Subclinical epileptiform activity in the Alzheimer continuum: association with disease, cognition and detection method.
Nous A, Seynaeve L, Feys O, Wens V, De Tiège X, Van Mierlo P, Baroumand AG, Nieboer K, Allemeersch GJ, Mangelschots S, Michiels V, van der Zee J, Van Broeckhoven C, Ribbens A, Houbrechts R, De Witte S, Wittens MMJ, Bjerke M, Vanlersberghe C, Ceyssens S, Nagels G, Smolders I, Engelborghs S
Alzheimers Res Ther 2024 Jan 23;16(1):19. doi: 10.1186/s13195-023-01373-9. PMID: 38263073Free PMC Article
Zero-crossing patterns reveal subtle epileptiform discharges in the scalp EEG.
Pyrzowski J, Le Douget JE, Fouad A, Siemiński M, Jędrzejczak J, Le Van Quyen M
Sci Rep 2021 Feb 18;11(1):4128. doi: 10.1038/s41598-021-83337-3. PMID: 33602954Free PMC Article
Occipital lobe seizures and epilepsies.
Adcock JE, Panayiotopoulos CP
J Clin Neurophysiol 2012 Oct;29(5):397-407. doi: 10.1097/WNP.0b013e31826c98fe. PMID: 23027097
Frontal lobe epilepsy.
Kellinghaus C, Lüders HO
Epileptic Disord 2004 Dec;6(4):223-39. PMID: 15634619

Prognosis

Epilepsy and EEG Abnormalities in Children with Autism Spectrum Disorders.
Sharma V, Saini AG, Malhi P, Singhi P
Indian J Pediatr 2022 Oct;89(10):975-982. Epub 2021 Nov 29 doi: 10.1007/s12098-021-03928-w. PMID: 34843062
Features of intracranial interictal epileptiform discharges associated with memory encoding.
Quon RJ, Camp EJ, Meisenhelter S, Song Y, Steimel SA, Testorf ME, Andrew AS, Gross RE, Lega BC, Sperling MR, Kahana MJ, Jobst BC
Epilepsia 2021 Nov;62(11):2615-2626. Epub 2021 Sep 5 doi: 10.1111/epi.17060. PMID: 34486107Free PMC Article
Epilepsy With Eyelid Myoclonia (Jeavons Syndrome).
Zawar I, Knight EP
Pediatr Neurol 2021 Aug;121:75-80. Epub 2020 Dec 1 doi: 10.1016/j.pediatrneurol.2020.11.018. PMID: 34167046
Mesial temporal lobe epilepsy.
Tatum WO 4th
J Clin Neurophysiol 2012 Oct;29(5):356-65. doi: 10.1097/WNP.0b013e31826b3ab7. PMID: 23027091
Frontal lobe epilepsy.
Kellinghaus C, Lüders HO
Epileptic Disord 2004 Dec;6(4):223-39. PMID: 15634619

Clinical prediction guides

Altered Sleep Microarchitecture and Cognitive Impairment in Patients With Temporal Lobe Epilepsy.
Bender AC, Jaleel A, Pellerin KR, Moguilner S, Sarkis RA, Cash SS, Lam AD
Neurology 2023 Dec 4;101(23):e2376-e2387. doi: 10.1212/WNL.0000000000207942. PMID: 37848332Free PMC Article
Epilepsy and EEG Abnormalities in Children with Autism Spectrum Disorders.
Sharma V, Saini AG, Malhi P, Singhi P
Indian J Pediatr 2022 Oct;89(10):975-982. Epub 2021 Nov 29 doi: 10.1007/s12098-021-03928-w. PMID: 34843062
Epilepsy With Eyelid Myoclonia (Jeavons Syndrome).
Zawar I, Knight EP
Pediatr Neurol 2021 Aug;121:75-80. Epub 2020 Dec 1 doi: 10.1016/j.pediatrneurol.2020.11.018. PMID: 34167046
A reliable interictal EEG grading scale for children with infantile spasms - The 2021 BASED score.
Mytinger JR, Vidaurre J, Moore-Clingenpeel M, Stanek JR, Albert DVF
Epilepsy Res 2021 Jul;173:106631. Epub 2021 Apr 2 doi: 10.1016/j.eplepsyres.2021.106631. PMID: 33839516
Mesial temporal lobe epilepsy.
Tatum WO 4th
J Clin Neurophysiol 2012 Oct;29(5):356-65. doi: 10.1097/WNP.0b013e31826b3ab7. PMID: 23027091

Recent systematic reviews

Human Herpes Virus 6 Encephalitis Presenting as Fatal Refractory Status Epilepticus: a Case Report and Systematic Review.
Ocampo FF, Tipones RN, Jamora RDG
Acta Neurol Taiwan 2021 Mar;30(1):21-26. PMID: 34549397
Electroencephalographic findings in antileucine-rich glioma-inactivated 1 (LGI1) autoimmune encephalitis: A systematic review.
Roberto KT, Espiritu AI, Fernandez MLL, Gutierrez JC
Epilepsy Behav 2020 Nov;112:107462. Epub 2020 Sep 22 doi: 10.1016/j.yebeh.2020.107462. PMID: 32971385
Palinacousis--evidence to suggest a post-ictal phenomenon.
Mohamed W, Ahuja N, Shah A
J Neurol Sci 2012 Jun 15;317(1-2):6-12. Epub 2012 Mar 11 doi: 10.1016/j.jns.2012.02.016. PMID: 22414800

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