U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Glycogen-rich clear cell breast carcinoma

MedGen UID:
1785052
•Concept ID:
C2012261
•
Neoplastic Process
Synonyms: Breast Glycogen-Rich Carcinoma; Breast Glycogen-Rich, Clear Cell Carcinoma; glycogen-rich clear cell breast carcinoma; Glycogen-Rich, Clear Cell Breast Carcinoma; glycogen-rich, clear cell breast carcinoma
 
Monarch Initiative: MONDO:0003390

Definition

An uncommon, usually aggressive adenocarcinoma of the breast characterized by the presence of clear cells that contain glycogen. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGlycogen-rich clear cell breast carcinoma

Recent clinical studies

Etiology

Clear cell acanthoma (CCA)-like lesions of the nipple/areola: A clinicopathological study of 12 cases supporting a nonneoplastic eczematous disease.
Kuo KL, Lo CS, Lee LY, Yang CH, Kuo TT
J Am Acad Dermatol 2019 Mar;80(3):749-755. Epub 2018 Dec 14 doi: 10.1016/j.jaad.2016.07.032. PMID: 30558902
Clinicopathologic characteristics and prognosis of glycogen-rich clear cell carcinoma of the breast.
Ma X, Han Y, Fan Y, Cao X, Wang X
Breast J 2014 Mar-Apr;20(2):166-73. Epub 2014 Jan 9 doi: 10.1111/tbj.12231. PMID: 24400866
Clear cell carcinoma of the breast with immunohistochemical evidence of divergent differentiation.
Shirley SE, Escoffery CT, Titus IP, Williams EE, West AB
Ann Diagn Pathol 2002 Aug;6(4):250-6. doi: 10.1053/adpa.2002.35399. PMID: 12170458
Clear cell 'sugar' tumor of the breast: another extrapulmonary site and review of the literature.
Govender D, Sabaratnam RM, Essa AS
Am J Surg Pathol 2002 May;26(5):670-5. doi: 10.1097/00000478-200205000-00014. PMID: 11979098
Glycogen-rich clear cell carcinomas of the breast. A clinicopathologic and ultrastructural study.
Hull MT, Warfel KA
Am J Surg Pathol 1986 Aug;10(8):553-9. doi: 10.1097/00000478-198608000-00005. PMID: 3017138

Diagnosis

Glycogen-rich Clear Cell Carcinoma of the Breast: A Comprehensive Review.
Vranic S, Skenderi F, Beslagic V, Gatalica Z
Appl Immunohistochem Mol Morphol 2020 Oct;28(9):655-660. doi: 10.1097/PAI.0000000000000850. PMID: 32167940
Clinicopathologic characteristics and prognosis of glycogen-rich clear cell carcinoma of the breast.
Ma X, Han Y, Fan Y, Cao X, Wang X
Breast J 2014 Mar-Apr;20(2):166-73. Epub 2014 Jan 9 doi: 10.1111/tbj.12231. PMID: 24400866
Clinical and pathological features of glycogen-rich clear cell carcinoma of the breast.
Kuroda H, Sakamoto G, Ohnisi K, Itoyama S
Breast Cancer 2005;12(3):189-95. doi: 10.2325/jbcs.12.189. PMID: 16110288
Glycogen-rich clear cell mammary malignant myoepithelioma.
Son HJ, Jung SH, Lee SY, Moon WS
Breast 2004 Dec;13(6):506-9. doi: 10.1016/j.breast.2004.07.003. PMID: 15563859
Glycogen-rich clear-cell carcinoma of the breast: a clinicopathologic and flow cytometric study.
Toikkanen S, Joensuu H
Hum Pathol 1991 Jan;22(1):81-3. doi: 10.1016/0046-8177(91)90066-x. PMID: 1985082

Therapy

Glycogen-rich carcinomas of the breast display unique characteristics with respect to proliferation and the frequency of oligonucleosomal fragments.
Varga Z, Caduff R
Breast Cancer Res Treat 1999 Sep;57(2):215-9. doi: 10.1023/a:1006285819701. PMID: 10598049
Clear cell myoepithelial neoplasm of the breast.
Cartagena N Jr, Cabello-Inchausti B, Willis I, Poppiti R Jr
Hum Pathol 1988 Oct;19(10):1239-43. doi: 10.1016/s0046-8177(88)80159-x. PMID: 2844648

Prognosis

Glycogen-rich Clear Cell Carcinoma of the Breast: A Comprehensive Review.
Vranic S, Skenderi F, Beslagic V, Gatalica Z
Appl Immunohistochem Mol Morphol 2020 Oct;28(9):655-660. doi: 10.1097/PAI.0000000000000850. PMID: 32167940
Clinicopathologic characteristics and prognosis of glycogen-rich clear cell carcinoma of the breast.
Ma X, Han Y, Fan Y, Cao X, Wang X
Breast J 2014 Mar-Apr;20(2):166-73. Epub 2014 Jan 9 doi: 10.1111/tbj.12231. PMID: 24400866
Immunophenotypes of glycogen rich clear cell carcinoma.
Kim SE, Koo JS, Jung WH
Yonsei Med J 2012 Nov 1;53(6):1142-6. doi: 10.3349/ymj.2012.53.6.1142. PMID: 23074114Free PMC Article
Clinical and pathological features of glycogen-rich clear cell carcinoma of the breast.
Kuroda H, Sakamoto G, Ohnisi K, Itoyama S
Breast Cancer 2005;12(3):189-95. doi: 10.2325/jbcs.12.189. PMID: 16110288
Glycogen-rich clear-cell carcinoma of the breast: a clinicopathologic and flow cytometric study.
Toikkanen S, Joensuu H
Hum Pathol 1991 Jan;22(1):81-3. doi: 10.1016/0046-8177(91)90066-x. PMID: 1985082

Clinical prediction guides

Clinicopathological characteristics of breast sebaceous adenocarcinoma.
Heng C, Wei T, Yingbing T, Hanzhong L
Pol J Pathol 2018;69(3):226-233. doi: 10.5114/pjp.2018.79542. PMID: 30509049
Clinicopathologic characteristics and prognosis of glycogen-rich clear cell carcinoma of the breast.
Ma X, Han Y, Fan Y, Cao X, Wang X
Breast J 2014 Mar-Apr;20(2):166-73. Epub 2014 Jan 9 doi: 10.1111/tbj.12231. PMID: 24400866
Histopathological and immunohistochemical findings in a case of glycogen-rich clear cell carcinoma of the breast.
Takekawa Y, Kubo A, Morita T, Kameda K, Kimura M, Sakakibara M, Yoshii R, Yamashita Y
Rinsho Byori 2006 Jan;54(1):27-30. PMID: 16499226
Cytology of glycogen-rich (clear cell) carcinoma of the breast. A report of two cases.
Kern SB, Andera L
Acta Cytol 1997 Mar-Apr;41(2):556-60. doi: 10.1159/000332556. PMID: 9100798
Intralobular growth of myoepithelial cell carcinoma of the breast.
Soares J, Tomasic G, Bucciarelli E, Eusebi V
Virchows Arch 1994;425(2):205-10. doi: 10.1007/BF00230358. PMID: 7952505

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...