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Lacrimal Drainage System Squamous Cell Carcinoma

MedGen UID:
1783481
•Concept ID:
C5447980
•
Neoplastic Process
Synonym: Squamous Cell Carcinoma of the Lacrimal Drainage System

Definition

A squamous cell carcinoma that arises from the lacrimal sac and/or canaliculi. it is exceedingly rare in the nasolacrimal duct. (WHO 2018) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLacrimal Drainage System Squamous Cell Carcinoma

Professional guidelines

PubMed

The role of lacrimal intubation in the management of facial trauma and tumor resection.
Spinelli HM, Shapiro MD, Wei LL, Elahi E, Hirmand H
Plast Reconstr Surg 2005 Jun;115(7):1871-6. doi: 10.1097/01.prs.0000164687.41948.62. PMID: 15923831

Recent clinical studies

Etiology

Human papillomavirus-related neoplasia of the ocular adnexa.
Ramberg IMS
Acta Ophthalmol 2022 Oct;100 Suppl 272(Suppl 272):3-33. doi: 10.1111/aos.15244. PMID: 36203222Free PMC Article
Holding back the tears: is there a role for marsupialisation?
Chiu SJ, Currie ZI, Tan JH
BMJ Open Ophthalmol 2022 Aug;7(1) doi: 10.1136/bmjophth-2022-000985. PMID: 36161857Free PMC Article
Clinical profile and management outcomes of lacrimal drainage system malignancies.
Alam MS, Mukherjee B, Krishnakumar S
Orbit 2022 Aug;41(4):429-436. Epub 2021 May 21 doi: 10.1080/01676830.2021.1925932. PMID: 34018461
Human Papillomavirus Related Neoplasia of the Ocular Adnexa.
Ramberg I, Heegaard S
Viruses 2021 Aug 2;13(8) doi: 10.3390/v13081522. PMID: 34452388Free PMC Article
Tumors of the lacrimal drainage system.
Heindl LM, Jünemann AG, Kruse FE, Holbach LM
Orbit 2010 Oct;29(5):298-306. doi: 10.3109/01676830.2010.492887. PMID: 20958177

Diagnosis

Human papillomavirus-related neoplasia of the ocular adnexa.
Ramberg IMS
Acta Ophthalmol 2022 Oct;100 Suppl 272(Suppl 272):3-33. doi: 10.1111/aos.15244. PMID: 36203222Free PMC Article
Clinical profile and management outcomes of lacrimal drainage system malignancies.
Alam MS, Mukherjee B, Krishnakumar S
Orbit 2022 Aug;41(4):429-436. Epub 2021 May 21 doi: 10.1080/01676830.2021.1925932. PMID: 34018461
Human Papillomavirus Related Neoplasia of the Ocular Adnexa.
Ramberg I, Heegaard S
Viruses 2021 Aug 2;13(8) doi: 10.3390/v13081522. PMID: 34452388Free PMC Article
Primary Malignant Epithelial Tumors of the Lacrimal Drainage System: A Major Review.
Singh S, Ali MJ
Orbit 2021 Jun;40(3):179-192. Epub 2020 Jun 8 doi: 10.1080/01676830.2020.1769684. PMID: 32506982
Squamous cell carcinoma of the lacrimal drainage system: case report and literature review.
De Stefani A, Lerda W, Usai A, Cavalot A, Riella P, Bussi M
Tumori 1998 Jul-Aug;84(4):506-10. doi: 10.1177/030089169808400414. PMID: 9825006

Therapy

Conjunctival squamous cell carcinoma following psoriasis treatment.
Almousa R, Daya S, Lake D, Richardson T, Malhotra R
J Cutan Med Surg 2012 Sep-Oct;16(5):365-7. doi: 10.1177/120347541201600517. PMID: 22971315
Nasolacrimal obstruction after maxillary sinus and rhinoplastic surgery.
Osguthorpe JD, Calcaterra TC
Arch Otolaryngol 1979 May;105(5):264-6. doi: 10.1001/archotol.1979.00790170034009. PMID: 435149

Prognosis

Human papillomavirus-related neoplasia of the ocular adnexa.
Ramberg IMS
Acta Ophthalmol 2022 Oct;100 Suppl 272(Suppl 272):3-33. doi: 10.1111/aos.15244. PMID: 36203222Free PMC Article
Human Papillomavirus Related Neoplasia of the Ocular Adnexa.
Ramberg I, Heegaard S
Viruses 2021 Aug 2;13(8) doi: 10.3390/v13081522. PMID: 34452388Free PMC Article
Primary Malignant Epithelial Tumors of the Lacrimal Drainage System: A Major Review.
Singh S, Ali MJ
Orbit 2021 Jun;40(3):179-192. Epub 2020 Jun 8 doi: 10.1080/01676830.2020.1769684. PMID: 32506982
Combined External, Endoscopic, Endonasal-Assisted En Bloc Resection of Malignant Tumors From the Lacrimal Drainage System.
Shi J, Tu Y, Wu W
J Craniofac Surg 2018 Oct;29(7):1855-1858. doi: 10.1097/SCS.0000000000004655. PMID: 29944561
Tumors of the lacrimal drainage system.
Heindl LM, Jünemann AG, Kruse FE, Holbach LM
Orbit 2010 Oct;29(5):298-306. doi: 10.3109/01676830.2010.492887. PMID: 20958177

Clinical prediction guides

Human papillomavirus-related neoplasia of the ocular adnexa.
Ramberg IMS
Acta Ophthalmol 2022 Oct;100 Suppl 272(Suppl 272):3-33. doi: 10.1111/aos.15244. PMID: 36203222Free PMC Article
Human Papillomavirus Related Neoplasia of the Ocular Adnexa.
Ramberg I, Heegaard S
Viruses 2021 Aug 2;13(8) doi: 10.3390/v13081522. PMID: 34452388Free PMC Article

Recent systematic reviews

Holding back the tears: is there a role for marsupialisation?
Chiu SJ, Currie ZI, Tan JH
BMJ Open Ophthalmol 2022 Aug;7(1) doi: 10.1136/bmjophth-2022-000985. PMID: 36161857Free PMC Article

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