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Pulmonary mycetoma

MedGen UID:: 1780982
•Concept ID:: C5539745
•: Finding

Synonym:	Lung fungus ball

HPO:	HP:0033651

Definition

A mycetoma is a discrete mass of intertwined hyphae, usually of an Aspergillus species, matted together by mucus, fibrin, and cellular debris colonizing a cavity, usually from prior fibrocavitary disease (eg, tuberculosis or sarcoidosis). A mycetoma may move to a dependent location when the patient changes position and may show an air crescent sign. CT scans may show a spongelike pattern and foci of calcification in the mycetoma. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVPulmonary mycetoma

Phenotypic abnormality
- Abnormality of the respiratory system
  - Abnormal respiratory system physiology
    - Abnormal respiratory system morphology
      - Abnormal pulmonary thoracic imaging finding
        Pulmonary mycetoma

Professional guidelines

PubMed

Chronic pulmonary aspergillosis: rationale and clinical guidelines for diagnosis and management.

Denning DW, Cadranel J, Beigelman-Aubry C, Ader F, Chakrabarti A, Blot S, Ullmann AJ, Dimopoulos G, Lange C; European Society for Clinical Microbiology and Infectious Diseases and European Respiratory Society
Eur Respir J 2016 Jan;47(1):45-68. doi: 10.1183/13993003.00583-2015. PMID: 26699723

External beam radiotherapy: a treatment option for massive haemoptysis caused by mycetoma.

Falkson C, Sur R, Pacella J
Clin Oncol (R Coll Radiol) 2002 Jun;14(3):233-5. doi: 10.1053/clon.2002.0063. PMID: 12109828

Endocavitary treatment of pulmonary mycetomas.

Adelson HT, Malcolm JA
Am Rev Respir Dis 1968 Jul;98(1):87-92. doi: 10.1164/arrd.1968.98.1.87. PMID: 5657155

See all (18)

Recent clinical studies

Etiology

Late-onset sarcoidosis: a comparative study.

Varron L, Cottin V, Schott AM, Broussolle C, Sève P
Medicine (Baltimore) 2012 May;91(3):137-143. doi: 10.1097/MD.0b013e3182569f91. PMID: 22543629

Therapeutic approach in pulmonary mycetoma. Analysis of 27 patients.

Mariotta S, Giuffreda E, Tramontano F, Treggiari S, Ricci A, Schmid G
Panminerva Med 2001 Sep;43(3):161-5. PMID: 11579328

Pulmonary mycetoma due to Candida albicans: case report and review.

Shelly MA, Poe RH, Kapner LB
Clin Infect Dis 1996 Jan;22(1):133-5. doi: 10.1093/clinids/22.1.133. PMID: 8824978

Spontaneous pneumothorax complicating pulmonary mycetoma in patients with acute leukemia.

Martino P, Girmenia C, Venditti M, Micozzi A, Gentile G, Raccah R, Martinelli E, Rendina E, Mandelli F
Rev Infect Dis 1990 Jul-Aug;12(4):611-7. doi: 10.1093/clinids/12.4.611. PMID: 2385767

Pulmonary mycetoma following Mycobacterium kansasii infection. Report of seven cases.

Maliwan N, Zvetina JR
Arch Intern Med 1985 Dec;145(12):2180-3. PMID: 4074030

See all (8)

Diagnosis

Pulmonary mycetoma.

Ramasamy A, Kadom Z, Dubrey SW
Br J Hosp Med (Lond) 2014 Nov;75(11):656. doi: 10.12968/hmed.2014.75.11.656. PMID: 25383441

Pulmonary coccidioidal pseudomycetoma.

Rodriguez-Cintron W, Fraire AE, Greenberg SD, Stevens PM, Stager CE
Diagn Microbiol Infect Dis 1992 Mar-Apr;15(3):267-72. doi: 10.1016/0732-8893(92)90123-b. PMID: 1582169

Pulmonary mycetoma.

Lancet 1968 Aug 24;2(7565):439-41. PMID: 4174162

DIAGNOSTIC PRECIPITIN TEST IN ASPERGILLUS PULMONARY MYCETOMA.

LONGBOTTOM JL, PEPYS J, CLIVE FT
Lancet 1964 Mar 14;1(7333):588-9. doi: 10.1016/s0140-6736(64)91335-2. PMID: 14104489

PULMONARY MYCETOMA.

TELLESSON WG
J Coll Radiol Australas 1963 Oct;7:193-7. PMID: 14074370

See all (21)

Therapy

Late-onset sarcoidosis: a comparative study.

Varron L, Cottin V, Schott AM, Broussolle C, Sève P
Medicine (Baltimore) 2012 May;91(3):137-143. doi: 10.1097/MD.0b013e3182569f91. PMID: 22543629

Intracavitary voriconazole for the treatment of hemoptysis complicating Pseudallescheria angusta pulmonary mycetomas in fibrocystic sarcoidosis.

Kravitz JN, Steed LL, Judson MA
Med Mycol 2011 Feb;49(2):198-201. Epub 2010 Sep 10 doi: 10.3109/13693786.2010.512619. PMID: 20831365

Therapeutic approach in pulmonary mycetoma. Analysis of 27 patients.

Mariotta S, Giuffreda E, Tramontano F, Treggiari S, Ricci A, Schmid G
Panminerva Med 2001 Sep;43(3):161-5. PMID: 11579328

Pulmonary mycetoma probably due to Candida albicans with complete resolution.

Abel AT, Parwer S, Sanyal SC
Respir Med 1998 Aug;92(8):1079-80. doi: 10.1016/s0954-6111(98)90359-6. PMID: 9893780

Acute pulmonary mycetoma due to Candida albicans with complete resolution.

Watanakunakorn C
J Infect Dis 1983 Dec;148(6):1131. doi: 10.1093/infdis/148.6.1131. PMID: 6581234

See all (8)

Prognosis

Late-onset sarcoidosis: a comparative study.

Varron L, Cottin V, Schott AM, Broussolle C, Sève P
Medicine (Baltimore) 2012 May;91(3):137-143. doi: 10.1097/MD.0b013e3182569f91. PMID: 22543629

Pulmonary mycetoma due to Candida albicans: case report and review.

Shelly MA, Poe RH, Kapner LB
Clin Infect Dis 1996 Jan;22(1):133-5. doi: 10.1093/clinids/22.1.133. PMID: 8824978

Spontaneous pneumothorax complicating pulmonary mycetoma in patients with acute leukemia.

Martino P, Girmenia C, Venditti M, Micozzi A, Gentile G, Raccah R, Martinelli E, Rendina E, Mandelli F
Rev Infect Dis 1990 Jul-Aug;12(4):611-7. doi: 10.1093/clinids/12.4.611. PMID: 2385767

Apparent pulmonary mycetoma following invasive aspergillosis in neutropenic patients.

Kibbler CC, Milkins SR, Bhamra A, Spiteri MA, Noone P, Prentice HG
Thorax 1988 Feb;43(2):108-12. doi: 10.1136/thx.43.2.108. PMID: 3281310 Free PMC Article

Pulmonary mycetoma following Mycobacterium kansasii infection. Report of seven cases.

Maliwan N, Zvetina JR
Arch Intern Med 1985 Dec;145(12):2180-3. PMID: 4074030

See all (7)