U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Urinary space collagenization

MedGen UID:
1780588
•Concept ID:
C5539507
•
Finding
Synonym: Collagenization of the urinary space
 
HPO: HP:0033313

Definition

Acellular collagenous matrix within Bowman's space, not associated with extracapillary hypercellularity or necrosis, associated with sclerosis or deflation of the tuft. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUrinary space collagenization

Professional guidelines

PubMed

Melatonin serves as a novel treatment in bladder fibrosis through TGF-β1/Smad and EMT.
Zhang Y, Gong S, He W, Yuan J, Dong D, Zhang J, Wang H, Chen B
PLoS One 2024;19(3):e0295104. Epub 2024 Mar 13 doi: 10.1371/journal.pone.0295104. PMID: 38478501Free PMC Article

Recent clinical studies

Etiology

Biomarkers of inflammation - LBP and TLR- predict progression of knee osteoarthritis in the DOXY clinical trial.
Huang ZY, Perry E, Huebner JL, Katz B, Li YJ, Kraus VB
Osteoarthritis Cartilage 2018 Dec;26(12):1658-1665. Epub 2018 Aug 23 doi: 10.1016/j.joca.2018.08.005. PMID: 30144513Free PMC Article
Association of urinary biomarker COLL2-1NO₂ with incident clinical and radiographic knee OA in overweight and obese women.
Landsmeer ML, Runhaar J, Henrotin YE, Middelkoop van M, Oei EH, Vroegindeweij D, Reijman M, van Osch GJ, Koes BW, Bindels PJ, Bierma-Zeinstra SM
Osteoarthritis Cartilage 2015 Aug;23(8):1398-404. Epub 2015 Apr 17 doi: 10.1016/j.joca.2015.04.011. PMID: 25891749
Amino acid supplementation alters bone metabolism during simulated weightlessness.
Zwart SR, Davis-Street JE, Paddon-Jones D, Ferrando AA, Wolfe RR, Smith SM
J Appl Physiol (1985) 2005 Jul;99(1):134-40. Epub 2005 Feb 3 doi: 10.1152/japplphysiol.01406.2004. PMID: 15691900
New insights into mechanisms of fibrosis in immune renal injury.
Strutz F, Neilson EG
Springer Semin Immunopathol 2003 May;24(4):459-76. doi: 10.1007/s00281-003-0123-5. PMID: 12778339
Hormonal control of collagen metabolism--Part I.
Kucharz EJ
Endocrinologie 1988 Apr-Jun;26(2):69-79. PMID: 3045946

Diagnosis

Disruption of the glomerular basement membrane associated with nutcracker syndrome and double inferior vena cava in Noonan syndrome: a case report.
Omori A, Katayama K, Saiki R, Masui S, Suzuki K, Kanii Y, Tsujimoto K, Nakamori S, Kurita T, Murata T, Inoue T, Dohi K
BMC Nephrol 2022 Feb 12;23(1):65. doi: 10.1186/s12882-022-02671-4. PMID: 35151252Free PMC Article
Extracellular Matrix in Kidney Fibrosis: More Than Just a Scaffold.
Bülow RD, Boor P
J Histochem Cytochem 2019 Sep;67(9):643-661. Epub 2019 May 22 doi: 10.1369/0022155419849388. PMID: 31116062Free PMC Article
Biomarkers of inflammation - LBP and TLR- predict progression of knee osteoarthritis in the DOXY clinical trial.
Huang ZY, Perry E, Huebner JL, Katz B, Li YJ, Kraus VB
Osteoarthritis Cartilage 2018 Dec;26(12):1658-1665. Epub 2018 Aug 23 doi: 10.1016/j.joca.2018.08.005. PMID: 30144513Free PMC Article
Pseudoangiosarcomatous urothelial carcinoma of the urinary bladder.
Paner GP, Cox RM, Richards K, Akki A, Gokden N, Lopez-Beltran A, Krausz T, McKenney JK, Steinberg GD
Am J Surg Pathol 2014 Sep;38(9):1251-9. doi: 10.1097/PAS.0000000000000241. PMID: 25133708
Pelvic neurilemmoma.
Prkacin I, Martinac M, Sabljar-Matovinović M, Skegro D, Mazalin J
Acta Med Croatica 2001;55(2):97-100. PMID: 11505636

Therapy

Biomarkers of inflammation - LBP and TLR- predict progression of knee osteoarthritis in the DOXY clinical trial.
Huang ZY, Perry E, Huebner JL, Katz B, Li YJ, Kraus VB
Osteoarthritis Cartilage 2018 Dec;26(12):1658-1665. Epub 2018 Aug 23 doi: 10.1016/j.joca.2018.08.005. PMID: 30144513Free PMC Article
Dietary acid load and bone turnover during long-duration spaceflight and bed rest.
Zwart SR, Rice BL, Dlouhy H, Shackelford LC, Heer M, Koslovsky MD, Smith SM
Am J Clin Nutr 2018 May 1;107(5):834-844. doi: 10.1093/ajcn/nqy029. PMID: 29722847Free PMC Article
Zingerone attenuates diabetic nephropathy through inhibition of nicotinamide adenine dinucleotide phosphate oxidase 4.
Cui Y, Shi Y, Bao Y, Wang S, Hua Q, Liu Y
Biomed Pharmacother 2018 Mar;99:422-430. doi: 10.1016/j.biopha.2018.01.051. PMID: 29367111
Tissue engineering in urethral reconstruction.
Cui T, Terlecki R, Atala A
Arch Esp Urol 2014 Jan-Feb;67(1):29-34. PMID: 24531669
Amino acid supplementation alters bone metabolism during simulated weightlessness.
Zwart SR, Davis-Street JE, Paddon-Jones D, Ferrando AA, Wolfe RR, Smith SM
J Appl Physiol (1985) 2005 Jul;99(1):134-40. Epub 2005 Feb 3 doi: 10.1152/japplphysiol.01406.2004. PMID: 15691900

Prognosis

Biomarkers of inflammation - LBP and TLR- predict progression of knee osteoarthritis in the DOXY clinical trial.
Huang ZY, Perry E, Huebner JL, Katz B, Li YJ, Kraus VB
Osteoarthritis Cartilage 2018 Dec;26(12):1658-1665. Epub 2018 Aug 23 doi: 10.1016/j.joca.2018.08.005. PMID: 30144513Free PMC Article
Association of urinary biomarker COLL2-1NO₂ with incident clinical and radiographic knee OA in overweight and obese women.
Landsmeer ML, Runhaar J, Henrotin YE, Middelkoop van M, Oei EH, Vroegindeweij D, Reijman M, van Osch GJ, Koes BW, Bindels PJ, Bierma-Zeinstra SM
Osteoarthritis Cartilage 2015 Aug;23(8):1398-404. Epub 2015 Apr 17 doi: 10.1016/j.joca.2015.04.011. PMID: 25891749
Pseudoangiosarcomatous urothelial carcinoma of the urinary bladder.
Paner GP, Cox RM, Richards K, Akki A, Gokden N, Lopez-Beltran A, Krausz T, McKenney JK, Steinberg GD
Am J Surg Pathol 2014 Sep;38(9):1251-9. doi: 10.1097/PAS.0000000000000241. PMID: 25133708
Bone markers, calcium metabolism, and calcium kinetics during extended-duration space flight on the mir space station.
Smith SM, Wastney ME, O'Brien KO, Morukov BV, Larina IM, Abrams SA, Davis-Street JE, Oganov V, Shackelford LC
J Bone Miner Res 2005 Feb;20(2):208-18. Epub 2004 Nov 8 doi: 10.1359/JBMR.041105. PMID: 15647814
Hypertensive nephrosclerosis in African Americans versus Caucasians.
Marcantoni C, Ma LJ, Federspiel C, Fogo AB
Kidney Int 2002 Jul;62(1):172-80. doi: 10.1046/j.1523-1755.2002.00420.x. PMID: 12081576

Clinical prediction guides

Biomarkers of inflammation - LBP and TLR- predict progression of knee osteoarthritis in the DOXY clinical trial.
Huang ZY, Perry E, Huebner JL, Katz B, Li YJ, Kraus VB
Osteoarthritis Cartilage 2018 Dec;26(12):1658-1665. Epub 2018 Aug 23 doi: 10.1016/j.joca.2018.08.005. PMID: 30144513Free PMC Article
Structure and Distribution of an Unrecognized Interstitium in Human Tissues.
Benias PC, Wells RG, Sackey-Aboagye B, Klavan H, Reidy J, Buonocore D, Miranda M, Kornacki S, Wayne M, Carr-Locke DL, Theise ND
Sci Rep 2018 Mar 27;8(1):4947. doi: 10.1038/s41598-018-23062-6. PMID: 29588511Free PMC Article
Unified theory on the pathogenesis of Randall's plaques and plugs.
Khan SR, Canales BK
Urolithiasis 2015 Jan;43 Suppl 1(0 1):109-23. Epub 2014 Aug 14 doi: 10.1007/s00240-014-0705-9. PMID: 25119506Free PMC Article
Pseudoangiosarcomatous urothelial carcinoma of the urinary bladder.
Paner GP, Cox RM, Richards K, Akki A, Gokden N, Lopez-Beltran A, Krausz T, McKenney JK, Steinberg GD
Am J Surg Pathol 2014 Sep;38(9):1251-9. doi: 10.1097/PAS.0000000000000241. PMID: 25133708
Hypertensive nephrosclerosis in African Americans versus Caucasians.
Marcantoni C, Ma LJ, Federspiel C, Fogo AB
Kidney Int 2002 Jul;62(1):172-80. doi: 10.1046/j.1523-1755.2002.00420.x. PMID: 12081576

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...