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Abnormal leukocyte physiology

MedGen UID:
1780121
Concept ID:
C5539815
Finding
HPO: HP:0033796

Definition

A functional abnormality of a white blood cell. [from HPO]

Professional guidelines

PubMed

Patnaik MM, Tefferi A
Am J Hematol 2024 Jun;99(6):1142-1165. Epub 2024 Mar 7 doi: 10.1002/ajh.27271. PMID: 38450850Free PMC Article
Giammarco S, Chiusolo P, Piccirillo N, Di Giovanni A, Metafuni E, Laurenti L, Sica S, Pagano L
Expert Rev Hematol 2017 Feb;10(2):147-154. Epub 2016 Dec 26 doi: 10.1080/17474086.2017.1270754. PMID: 27967252
Subcommittee on Urinary Tract Infection, Steering Committee on Quality Improvement and Management, Roberts KB
Pediatrics 2011 Sep;128(3):595-610. Epub 2011 Aug 28 doi: 10.1542/peds.2011-1330. PMID: 21873693

Recent clinical studies

Etiology

Nowotny HF, Marchant Seiter T, Ju J, Gottschlich A, Schneider H, Zopp S, Vogel F, Tschaidse L, Auer MK, Lottspeich C, Kobold S, Rothenfusser S, Beuschlein F, Reincke M, Braun L, Reisch N
Front Immunol 2023;14:1275828. Epub 2023 Nov 15 doi: 10.3389/fimmu.2023.1275828. PMID: 38045693Free PMC Article
Urschel D, Hernandez-Trujillo VP
Clin Rev Allergy Immunol 2022 Aug;63(1):99-105. Epub 2022 Feb 8 doi: 10.1007/s12016-022-08927-z. PMID: 35133619
Daich Varela M, Hufnagel RB, Guan B, Blain D, Sapp JC, Gropman AL, Alur R, Johnston JJ, Biesecker LG, Brooks BP
Ophthalmic Genet 2021 Jun;42(3):320-325. Epub 2021 Mar 15 doi: 10.1080/13816810.2021.1888127. PMID: 33719903Free PMC Article
Plander M, Kalman B
Autoimmunity 2016 Aug;49(5):285-97. Epub 2016 May 20 doi: 10.1080/08916934.2016.1183658. PMID: 27207228
Mouchtouris N, Jabbour PM, Starke RM, Hasan DM, Zanaty M, Theofanis T, Ding D, Tjoumakaris SI, Dumont AS, Ghobrial GM, Kung D, Rosenwasser RH, Chalouhi N
J Cereb Blood Flow Metab 2015 Feb;35(2):167-75. Epub 2014 Nov 19 doi: 10.1038/jcbfm.2014.179. PMID: 25407267Free PMC Article

Diagnosis

Dispenzieri A, Kourelis T, Buadi F
Hematol Oncol Clin North Am 2018 Feb;32(1):119-139. doi: 10.1016/j.hoc.2017.09.010. PMID: 29157614
Starr SP
FP Essent 2016 Nov;450:35-53. PMID: 27869441
Wong MT, Schölvinck EH, Lambeck AJ, van Ravenswaaij-Arts CM
Eur J Hum Genet 2015 Nov;23(11):1451-9. Epub 2015 Feb 18 doi: 10.1038/ejhg.2015.7. PMID: 25689927Free PMC Article
Cerny J, Rosmarin AG
Hematol Oncol Clin North Am 2012 Apr;26(2):303-19, viii. Epub 2012 Feb 17 doi: 10.1016/j.hoc.2012.01.001. PMID: 22463829
Wallace SL
Semin Arthritis Rheum 1974 Summer;3(4):369-81. doi: 10.1016/0049-0172(74)90006-7. PMID: 4598037

Therapy

Wu B, Zhong C, Lang Q, Liang Z, Zhang Y, Zhao X, Yu Y, Zhang H, Xu F, Tian Y
J Exp Clin Cancer Res 2021 Aug 25;40(1):267. doi: 10.1186/s13046-021-02068-5. PMID: 34433460Free PMC Article
Cencioni MT, Mattoscio M, Magliozzi R, Bar-Or A, Muraro PA
Nat Rev Neurol 2021 Jul;17(7):399-414. Epub 2021 Jun 1 doi: 10.1038/s41582-021-00498-5. PMID: 34075251
Liu S, Galat V, Galat Y, Lee YKA, Wainwright D, Wu J
J Hematol Oncol 2021 Jan 6;14(1):7. doi: 10.1186/s13045-020-01014-w. PMID: 33407739Free PMC Article
Barak Y, Nir E
Am J Pediatr Hematol Oncol 1987 Spring;9(1):42-55. doi: 10.1097/00043426-198721000-00008. PMID: 3296821
Knochel JP
West J Med 1981 Jan;134(1):15-26. PMID: 7010790Free PMC Article

Prognosis

Xiao MH, Wu S, Liang P, Ma D, Zhang J, Chen H, Zhong Z, Liu J, Jiang H, Feng X, Luo Z
EBioMedicine 2024 May;103:105138. Epub 2024 Apr 27 doi: 10.1016/j.ebiom.2024.105138. PMID: 38678809Free PMC Article
Jin W, Zheng Y, Zhu P
Autoimmun Rev 2022 Nov;21(11):103185. Epub 2022 Aug 27 doi: 10.1016/j.autrev.2022.103185. PMID: 36031049
Lakshminarayanan B, Davenport M
J Autoimmun 2016 Sep;73:1-9. Epub 2016 Jun 23 doi: 10.1016/j.jaut.2016.06.005. PMID: 27346637
Gonfiotti A, Jaus MO, Barale D, Baiguera S, Comin C, Lavorini F, Fontana G, Sibila O, Rombolà G, Jungebluth P, Macchiarini P
Lancet 2014 Jan 18;383(9913):238-44. Epub 2013 Oct 23 doi: 10.1016/S0140-6736(13)62033-4. PMID: 24161821
Gleich GJ, Klion AD, Lee JJ, Weller PF
Allergy 2013 Jul;68(7):829-35. Epub 2013 Jun 6 doi: 10.1111/all.12169. PMID: 23742015Free PMC Article

Clinical prediction guides

Xiao S, Kai Z, Murphy D, Li D, Patel D, Bielowka AM, Bernabeu-Herrero ME, Abdulmogith A, Mumford AD, Westbury SK, Aldred MA, Vargesson N, Caulfield MJ; Genomics England Research Consortium, Shovlin CL
Am J Hum Genet 2023 Nov 2;110(11):1903-1918. Epub 2023 Oct 9 doi: 10.1016/j.ajhg.2023.09.005. PMID: 37816352Free PMC Article
Bahado-Singh RO, Vishweswaraiah S, Aydas B, Yilmaz A, Metpally RP, Carey DJ, Crist RC, Berrettini WH, Wilson GD, Imam K, Maddens M, Bisgin H, Graham SF, Radhakrishna U
PLoS One 2021;16(3):e0248375. Epub 2021 Mar 31 doi: 10.1371/journal.pone.0248375. PMID: 33788842Free PMC Article
Čota S, Žagar I, Delimar V, Pap M, Perić D, Perić P
Rheumatol Int 2019 Sep;39(9):1655-1660. Epub 2019 Jun 18 doi: 10.1007/s00296-019-04346-0. PMID: 31214770
Kaul DK, Finnegan E, Barabino GA
Microcirculation 2009 Jan;16(1):97-111. doi: 10.1080/10739680802279394. PMID: 18720225Free PMC Article
Jones RL, Peterson CM
Am J Med 1981 Feb;70(2):339-52. doi: 10.1016/0002-9343(81)90771-3. PMID: 7008587

Recent systematic reviews

Frye RE, Rincon N, McCarty PJ, Brister D, Scheck AC, Rossignol DA
Neurobiol Dis 2024 Jul;197:106520. Epub 2024 May 3 doi: 10.1016/j.nbd.2024.106520. PMID: 38703861
Wei XY, Tan YQ, Zhou G
Inflamm Res 2024 May;73(5):867-876. Epub 2024 Apr 2 doi: 10.1007/s00011-024-01870-z. PMID: 38563967
Chen B, Yan Y, Wang H, Xu J
Aging Cell 2023 Jul;22(7):e13874. Epub 2023 May 26 doi: 10.1111/acel.13874. PMID: 37232505Free PMC Article
Subramaniam S, Kothari H, Bosmann M
Thromb Res 2022 Dec;220:35-47. Epub 2022 Oct 1 doi: 10.1016/j.thromres.2022.09.025. PMID: 36265412Free PMC Article
Zhao J, An Q, Zhu X, Yang B, Gao X, Niu Y, Zhang L, Xu K, Ma D
Stem Cell Res Ther 2022 Jun 3;13(1):230. doi: 10.1186/s13287-022-02912-1. PMID: 35659085Free PMC Article

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