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Locally Advanced Penile Carcinoma

MedGen UID:
1774354
•Concept ID:
C5418798
•
Neoplastic Process

Definition

Penile carcinoma that has spread to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Penile Carcinoma

Professional guidelines

PubMed

Extramammary Paget's Disease: Diagnosis, Pathogenesis, and Treatment with Focus on Recent Developments.
Ishizuki S, Nakamura Y
Curr Oncol 2021 Aug 5;28(4):2969-2986. doi: 10.3390/curroncol28040260. PMID: 34436026Free PMC Article
Management of Advanced Penile Cancer.
Chahoud J, Kohli M, Spiess PE
Mayo Clin Proc 2021 Mar;96(3):720-732. Epub 2020 Dec 9 doi: 10.1016/j.mayocp.2020.06.031. PMID: 33308870
Management of Penile Cancer.
Diorio GJ, Leone AR, Spiess PE
Urology 2016 Oct;96:15-21. Epub 2016 Jan 20 doi: 10.1016/j.urology.2015.12.041. PMID: 26802797

Recent clinical studies

Etiology

Paradigm Shifting Research: Key Studies in Urologic Oncology.
Dason S, Lee CT
Ann Surg Oncol 2024 Apr;31(4):2529-2537. Epub 2024 Feb 1 doi: 10.1245/s10434-023-14838-w. PMID: 38300402Free PMC Article
Immune-based therapies in penile cancer.
Joshi VB, Spiess PE, Necchi A, Pettaway CA, Chahoud J
Nat Rev Urol 2022 Aug;19(8):457-474. Epub 2022 Jul 18 doi: 10.1038/s41585-022-00617-x. PMID: 35851333
Penile cancer.
Thomas A, Necchi A, Muneer A, Tobias-Machado M, Tran ATH, Van Rompuy AS, Spiess PE, Albersen M
Nat Rev Dis Primers 2021 Feb 11;7(1):11. doi: 10.1038/s41572-021-00246-5. PMID: 33574340
Management of Advanced Penile Cancer.
Chahoud J, Kohli M, Spiess PE
Mayo Clin Proc 2021 Mar;96(3):720-732. Epub 2020 Dec 9 doi: 10.1016/j.mayocp.2020.06.031. PMID: 33308870
Advanced penile cancer.
Heinlen JE, Buethe DD, Culkin DJ
Int Urol Nephrol 2012 Feb;44(1):139-48. Epub 2011 Aug 4 doi: 10.1007/s11255-011-0011-1. PMID: 21814740

Diagnosis

Immune-based therapies in penile cancer.
Joshi VB, Spiess PE, Necchi A, Pettaway CA, Chahoud J
Nat Rev Urol 2022 Aug;19(8):457-474. Epub 2022 Jul 18 doi: 10.1038/s41585-022-00617-x. PMID: 35851333
Extramammary Paget's Disease: Diagnosis, Pathogenesis, and Treatment with Focus on Recent Developments.
Ishizuki S, Nakamura Y
Curr Oncol 2021 Aug 5;28(4):2969-2986. doi: 10.3390/curroncol28040260. PMID: 34436026Free PMC Article
Penile cancer.
Thomas A, Necchi A, Muneer A, Tobias-Machado M, Tran ATH, Van Rompuy AS, Spiess PE, Albersen M
Nat Rev Dis Primers 2021 Feb 11;7(1):11. doi: 10.1038/s41572-021-00246-5. PMID: 33574340
Management of Advanced Penile Cancer.
Chahoud J, Kohli M, Spiess PE
Mayo Clin Proc 2021 Mar;96(3):720-732. Epub 2020 Dec 9 doi: 10.1016/j.mayocp.2020.06.031. PMID: 33308870
Extramammary Paget disease.
St Claire K, Hoover A, Ashack K, Khachemoune A
Dermatol Online J 2019 Apr 15;25(4) PMID: 31046904

Therapy

Paradigm Shifting Research: Key Studies in Urologic Oncology.
Dason S, Lee CT
Ann Surg Oncol 2024 Apr;31(4):2529-2537. Epub 2024 Feb 1 doi: 10.1245/s10434-023-14838-w. PMID: 38300402Free PMC Article
Innovative systemic therapies for penile cancer.
Chahoud J, Pham R, Sonpavde G
Curr Opin Urol 2022 Jan 1;32(1):8-16. doi: 10.1097/MOU.0000000000000941. PMID: 34738984
Management of Advanced Penile Cancer.
Chahoud J, Kohli M, Spiess PE
Mayo Clin Proc 2021 Mar;96(3):720-732. Epub 2020 Dec 9 doi: 10.1016/j.mayocp.2020.06.031. PMID: 33308870
Radiotherapy approaches for locally advanced penile cancer: neoadjuvant and adjuvant.
Crook J
Curr Opin Urol 2017 Jan;27(1):62-67. doi: 10.1097/MOU.0000000000000346. PMID: 27584027
Advanced penile cancer.
Heinlen JE, Buethe DD, Culkin DJ
Int Urol Nephrol 2012 Feb;44(1):139-48. Epub 2011 Aug 4 doi: 10.1007/s11255-011-0011-1. PMID: 21814740

Prognosis

Immune-based therapies in penile cancer.
Joshi VB, Spiess PE, Necchi A, Pettaway CA, Chahoud J
Nat Rev Urol 2022 Aug;19(8):457-474. Epub 2022 Jul 18 doi: 10.1038/s41585-022-00617-x. PMID: 35851333
Extramammary Paget's Disease: Diagnosis, Pathogenesis, and Treatment with Focus on Recent Developments.
Ishizuki S, Nakamura Y
Curr Oncol 2021 Aug 5;28(4):2969-2986. doi: 10.3390/curroncol28040260. PMID: 34436026Free PMC Article
Penile cancer.
Thomas A, Necchi A, Muneer A, Tobias-Machado M, Tran ATH, Van Rompuy AS, Spiess PE, Albersen M
Nat Rev Dis Primers 2021 Feb 11;7(1):11. doi: 10.1038/s41572-021-00246-5. PMID: 33574340
Management of Advanced Penile Cancer.
Chahoud J, Kohli M, Spiess PE
Mayo Clin Proc 2021 Mar;96(3):720-732. Epub 2020 Dec 9 doi: 10.1016/j.mayocp.2020.06.031. PMID: 33308870
Extramammary Paget disease.
St Claire K, Hoover A, Ashack K, Khachemoune A
Dermatol Online J 2019 Apr 15;25(4) PMID: 31046904

Clinical prediction guides

Clinical Profile and Predictors of Survival in Carcinoma Penis Patients.
Garg V, Ray M, Haresh KP, Sahoo RK, Sharma A, Kaushal S, Batra A
Curr Oncol 2023 Apr 28;30(5):4563-4574. doi: 10.3390/curroncol30050345. PMID: 37232803Free PMC Article
Management of Advanced Penile Cancer.
Chahoud J, Kohli M, Spiess PE
Mayo Clin Proc 2021 Mar;96(3):720-732. Epub 2020 Dec 9 doi: 10.1016/j.mayocp.2020.06.031. PMID: 33308870
An update on systemic therapy for penile cancer.
Resch I, Abufaraj M, Hübner NA, Shariat SF
Curr Opin Urol 2020 Mar;30(2):229-233. doi: 10.1097/MOU.0000000000000733. PMID: 31972637
Extramammary Paget disease.
St Claire K, Hoover A, Ashack K, Khachemoune A
Dermatol Online J 2019 Apr 15;25(4) PMID: 31046904
EAU guidelines on primary urethral carcinoma.
Gakis G, Witjes JA, Compérat E, Cowan NC, De Santis M, Lebret T, Ribal MJ, Sherif AM; European Association of Urology
Eur Urol 2013 Nov;64(5):823-30. Epub 2013 Apr 2 doi: 10.1016/j.eururo.2013.03.044. PMID: 23582479

Recent systematic reviews

Repeat Transurethral Resection for Non-muscle-invasive Bladder Cancer: An Updated Systematic Review and Meta-analysis in the Contemporary Era.
Yanagisawa T, Kawada T, von Deimling M, Bekku K, Laukhtina E, Rajwa P, Chlosta M, Pradere B, D'Andrea D, Moschini M, Karakiewicz PI, Teoh JY, Miki J, Kimura T, Shariat SF
Eur Urol Focus 2024 Jan;10(1):41-56. Epub 2023 Jul 24 doi: 10.1016/j.euf.2023.07.002. PMID: 37495458
Systematic Review and Meta-Analysis-Is there a Benefit in Using Neoadjuvant Systemic Chemotherapy for Locally Advanced Penile Squamous Cell Carcinoma?
Azizi M, Aydin AM, Hajiran A, Lai A, Kumar A, Peyton CC, Minhas S, Sonpavde GP, Chahoud J, Pagliaro LC, Necchi A, Spiess PE
J Urol 2020 Jun;203(6):1147-1155. Epub 2020 Jan 13 doi: 10.1097/JU.0000000000000746. PMID: 31928407
Current Disease Management of Primary Urethral Carcinoma.
Janisch F, Abufaraj M, Fajkovic H, Kimura S, Iwata T, Nyirady P, Rink M, Shariat SF
Eur Urol Focus 2019 Sep;5(5):722-734. Epub 2019 Jul 13 doi: 10.1016/j.euf.2019.07.001. PMID: 31307949
Contemporary management of localized penile cancer.
Shapiro D, Shasha D, Tareen M, Tareen B
Expert Rev Anticancer Ther 2011 Jan;11(1):29-36. doi: 10.1586/era.10.209. PMID: 21166509

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