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Locally Advanced Adrenal Cortical Carcinoma

MedGen UID:
1772360
•Concept ID:
C5420780
•
Neoplastic Process
Synonym: Locally Advanced Adrenal Cortex Carcinoma

Definition

Adrenal cortical carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Adrenal Cortical Carcinoma

Professional guidelines

PubMed

American Association of Clinical Endocrinology Disease State Clinical Review on the Evaluation and Management of Adrenocortical Carcinoma in an Adult: a Practical Approach.
Kiseljak-Vassiliades K, Bancos I, Hamrahian A, Habra M, Vaidya A, Levine AC, Else T
Endocr Pract 2020 Nov;26(11):1366-1383. Epub 2020 Dec 14 doi: 10.4158/DSCR-2020-0567. PMID: 33875173Free PMC Article
Management of Adrenocortical Carcinoma.
Jasim S, Habra MA
Curr Oncol Rep 2019 Feb 23;21(3):20. doi: 10.1007/s11912-019-0773-7. PMID: 30798468
European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors.
Fassnacht M, Dekkers OM, Else T, Baudin E, Berruti A, de Krijger R, Haak HR, Mihai R, Assie G, Terzolo M
Eur J Endocrinol 2018 Oct 1;179(4):G1-G46. doi: 10.1530/EJE-18-0608. PMID: 30299884

Recent clinical studies

Etiology

Advances in Endocrine Surgery.
Lui MS, Shirali AS, Huang BL, Fisher SB, Perrier ND
Surg Oncol Clin N Am 2023 Jan;32(1):199-220. Epub 2022 Nov 3 doi: 10.1016/j.soc.2022.08.004. PMID: 36410918
American Association of Clinical Endocrinology Disease State Clinical Review on the Evaluation and Management of Adrenocortical Carcinoma in an Adult: a Practical Approach.
Kiseljak-Vassiliades K, Bancos I, Hamrahian A, Habra M, Vaidya A, Levine AC, Else T
Endocr Pract 2020 Nov;26(11):1366-1383. Epub 2020 Dec 14 doi: 10.4158/DSCR-2020-0567. PMID: 33875173Free PMC Article
Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1-2 trial.
Geoerger B, Kang HJ, Yalon-Oren M, Marshall LV, Vezina C, Pappo A, Laetsch TW, Petrilli AS, Ebinger M, Toporski J, Glade-Bender J, Nicholls W, Fox E, DuBois SG, Macy ME, Cohn SL, Pathiraja K, Diede SJ, Ebbinghaus S, Pinto N
Lancet Oncol 2020 Jan;21(1):121-133. Epub 2019 Dec 4 doi: 10.1016/S1470-2045(19)30671-0. PMID: 31812554
European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors.
Fassnacht M, Dekkers OM, Else T, Baudin E, Berruti A, de Krijger R, Haak HR, Mihai R, Assie G, Terzolo M
Eur J Endocrinol 2018 Oct 1;179(4):G1-G46. doi: 10.1530/EJE-18-0608. PMID: 30299884
Surgical treatment of adrenal carcinoma.
Gaujoux S, Weinandt M, Bonnet S, Reslinger V, Bertherat J, Dousset B
J Visc Surg 2017 Oct;154(5):335-343. Epub 2017 Jul 25 doi: 10.1016/j.jviscsurg.2017.06.010. PMID: 28754418

Diagnosis

Adrenocortical carcinoma: Diagnosis, prognostic classification and treatment of localized and advanced disease.
Libé R, Huillard O
Cancer Treat Res Commun 2023;37:100759. Epub 2023 Sep 8 doi: 10.1016/j.ctarc.2023.100759. PMID: 37690343
American Association of Clinical Endocrinology Disease State Clinical Review on the Evaluation and Management of Adrenocortical Carcinoma in an Adult: a Practical Approach.
Kiseljak-Vassiliades K, Bancos I, Hamrahian A, Habra M, Vaidya A, Levine AC, Else T
Endocr Pract 2020 Nov;26(11):1366-1383. Epub 2020 Dec 14 doi: 10.4158/DSCR-2020-0567. PMID: 33875173Free PMC Article
European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors.
Fassnacht M, Dekkers OM, Else T, Baudin E, Berruti A, de Krijger R, Haak HR, Mihai R, Assie G, Terzolo M
Eur J Endocrinol 2018 Oct 1;179(4):G1-G46. doi: 10.1530/EJE-18-0608. PMID: 30299884
Adrenocortical Carcinoma with Hypercortisolism.
Puglisi S, Perotti P, Pia A, Reimondo G, Terzolo M
Endocrinol Metab Clin North Am 2018 Jun;47(2):395-407. Epub 2018 Apr 9 doi: 10.1016/j.ecl.2018.02.003. PMID: 29754640
Surgical treatment of adrenal carcinoma.
Gaujoux S, Weinandt M, Bonnet S, Reslinger V, Bertherat J, Dousset B
J Visc Surg 2017 Oct;154(5):335-343. Epub 2017 Jul 25 doi: 10.1016/j.jviscsurg.2017.06.010. PMID: 28754418

Therapy

Adrenocortical carcinoma: Diagnosis, prognostic classification and treatment of localized and advanced disease.
Libé R, Huillard O
Cancer Treat Res Commun 2023;37:100759. Epub 2023 Sep 8 doi: 10.1016/j.ctarc.2023.100759. PMID: 37690343
American Association of Clinical Endocrinology Disease State Clinical Review on the Evaluation and Management of Adrenocortical Carcinoma in an Adult: a Practical Approach.
Kiseljak-Vassiliades K, Bancos I, Hamrahian A, Habra M, Vaidya A, Levine AC, Else T
Endocr Pract 2020 Nov;26(11):1366-1383. Epub 2020 Dec 14 doi: 10.4158/DSCR-2020-0567. PMID: 33875173Free PMC Article
European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors.
Fassnacht M, Dekkers OM, Else T, Baudin E, Berruti A, de Krijger R, Haak HR, Mihai R, Assie G, Terzolo M
Eur J Endocrinol 2018 Oct 1;179(4):G1-G46. doi: 10.1530/EJE-18-0608. PMID: 30299884
Adrenocortical Carcinoma with Hypercortisolism.
Puglisi S, Perotti P, Pia A, Reimondo G, Terzolo M
Endocrinol Metab Clin North Am 2018 Jun;47(2):395-407. Epub 2018 Apr 9 doi: 10.1016/j.ecl.2018.02.003. PMID: 29754640
Adrenocortical Carcinoma: A Clinician's Perspective.
Elfiky A
Surg Pathol Clin 2015 Dec;8(4):751-4. doi: 10.1016/j.path.2015.07.002. PMID: 26612225

Prognosis

Adrenocortical carcinoma: Diagnosis, prognostic classification and treatment of localized and advanced disease.
Libé R, Huillard O
Cancer Treat Res Commun 2023;37:100759. Epub 2023 Sep 8 doi: 10.1016/j.ctarc.2023.100759. PMID: 37690343
European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors.
Fassnacht M, Dekkers OM, Else T, Baudin E, Berruti A, de Krijger R, Haak HR, Mihai R, Assie G, Terzolo M
Eur J Endocrinol 2018 Oct 1;179(4):G1-G46. doi: 10.1530/EJE-18-0608. PMID: 30299884
Adrenocortical Carcinoma with Hypercortisolism.
Puglisi S, Perotti P, Pia A, Reimondo G, Terzolo M
Endocrinol Metab Clin North Am 2018 Jun;47(2):395-407. Epub 2018 Apr 9 doi: 10.1016/j.ecl.2018.02.003. PMID: 29754640
Surgical treatment of adrenal carcinoma.
Gaujoux S, Weinandt M, Bonnet S, Reslinger V, Bertherat J, Dousset B
J Visc Surg 2017 Oct;154(5):335-343. Epub 2017 Jul 25 doi: 10.1016/j.jviscsurg.2017.06.010. PMID: 28754418
Adrenocortical Carcinoma: A Clinician's Perspective.
Elfiky A
Surg Pathol Clin 2015 Dec;8(4):751-4. doi: 10.1016/j.path.2015.07.002. PMID: 26612225

Clinical prediction guides

Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1-2 trial.
Geoerger B, Kang HJ, Yalon-Oren M, Marshall LV, Vezina C, Pappo A, Laetsch TW, Petrilli AS, Ebinger M, Toporski J, Glade-Bender J, Nicholls W, Fox E, DuBois SG, Macy ME, Cohn SL, Pathiraja K, Diede SJ, Ebbinghaus S, Pinto N
Lancet Oncol 2020 Jan;21(1):121-133. Epub 2019 Dec 4 doi: 10.1016/S1470-2045(19)30671-0. PMID: 31812554
European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors.
Fassnacht M, Dekkers OM, Else T, Baudin E, Berruti A, de Krijger R, Haak HR, Mihai R, Assie G, Terzolo M
Eur J Endocrinol 2018 Oct 1;179(4):G1-G46. doi: 10.1530/EJE-18-0608. PMID: 30299884
Assessment and management of advanced adrenocortical carcinoma using a precision oncology care model.
Elfiky AA, Krishnan Nair HK
Discov Med 2016 Jan;21(113):49-56. PMID: 26896602
Adrenocortical Carcinoma: A Clinician's Perspective.
Elfiky A
Surg Pathol Clin 2015 Dec;8(4):751-4. doi: 10.1016/j.path.2015.07.002. PMID: 26612225
Radiotherapy in adrenocortical carcinoma.
Polat B, Fassnacht M, Pfreundner L, Guckenberger M, Bratengeier K, Johanssen S, Kenn W, Hahner S, Allolio B, Flentje M
Cancer 2009 Jul 1;115(13):2816-23. doi: 10.1002/cncr.24331. PMID: 19402169

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