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Refractory AL Amyloidosis

MedGen UID:
1750857
Concept ID:
C5420548
Neoplastic Process

Definition

AL amyloidosis that does not respond to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory AL Amyloidosis

Professional guidelines

PubMed

Abdallah M, Sanchorawala V
Am J Med 2022 Apr;135 Suppl 1:S30-S37. Epub 2022 Jan 23 doi: 10.1016/j.amjmed.2022.01.011. PMID: 35081382
Hassan H, Anwer F, Javaid A, Hashmi H
Crit Rev Oncol Hematol 2021 Sep;165:103435. Epub 2021 Jul 31 doi: 10.1016/j.critrevonc.2021.103435. PMID: 34343658
Smolewski P, Rydygier D
Expert Opin Investig Drugs 2019 May;28(5):421-433. Epub 2019 Apr 13 doi: 10.1080/13543784.2019.1596258. PMID: 30907163

Recent clinical studies

Therapy

Forgeard N, Elessa D, Carpinteiro A, Belhadj K, Minnema M, Roussel M, Huart A, Javaugue V, Pascal L, Royer B, Talbot A, Gounot R, Hegenbart U, Schonland S, Karlin L, Harel S, Kastritis E, Bridoux F, Jaccard A, Arnulf B
Blood 2024 Feb 22;143(8):734-737. doi: 10.1182/blood.2023022937. PMID: 38096365
Ravichandran S, Hall A, Jenner M, Garg M, Kishore B, Lachmann H, Gillmore J, Pitchford A, Oughton JB, Mahmood S, Sachchithantham S, Hawkins P, Brown S, Wechalekar A
Amyloid 2023 Sep;30(3):290-296. Epub 2023 May 22 doi: 10.1080/13506129.2023.2169124. PMID: 37216268
Abdallah M, Sanchorawala V
Am J Med 2022 Apr;135 Suppl 1:S30-S37. Epub 2022 Jan 23 doi: 10.1016/j.amjmed.2022.01.011. PMID: 35081382
Ehsan H, Rafae A, Masood A, Wahab A, Sana MK, Ansar I, Neupane K, Umar A, Ehsan A, Hashmi H
Clin Lymphoma Myeloma Leuk 2022 May;22(5):e285-e292. Epub 2021 Nov 1 doi: 10.1016/j.clml.2021.10.014. PMID: 34879994
Smolewski P, Rydygier D
Expert Opin Investig Drugs 2019 May;28(5):421-433. Epub 2019 Apr 13 doi: 10.1080/13543784.2019.1596258. PMID: 30907163

Prognosis

Shragai T, Gatt M, Lavie N, Vaxman I, Tadmor T, Rouvio O, Zektser M, Horowitz N, Magen H, Ballan M, Suru C, Luttwak E, Levi S, Ziv-Baran T, Avivi I, Cohen YC
Eur J Haematol 2021 Feb;106(2):184-195. Epub 2020 Nov 9 doi: 10.1111/ejh.13535. PMID: 33090552
Milani P, Sharpley F, Schönland SO, Basset M, Mahmood S, Nuvolone M, Kimmich C, Foli A, Sachchithanantham S, Merlini G, Wechalekar A, Palladini G, Hegenbart U
Amyloid 2020 Dec;27(4):231-236. Epub 2020 May 25 doi: 10.1080/13506129.2020.1767566. PMID: 32449385
Cohen OC, Brodermann MH, Blakeney IJ, Mahmood S, Sachchithanantham S, Ravichandran S, Law S, Lachmann HJ, Whelan CJ, Popat R, Rabin N, Yong K, Kyriakou C, Shah R, Cheesman S, Worthington S, Hawkins P, Gillmore JD, Wechalekar AD
Amyloid 2020 Sep;27(3):200-205. Epub 2020 May 15 doi: 10.1080/13506129.2020.1765768. PMID: 32408823
Lecumberri R, Krsnik I, Askari E, Sirvent M, González-Pérez MS, Escalante F, Pradillo V, Tamariz LE, Cánovas V, Alegre A, Gironella M, González-García ME, Infante MS, Lakhwani S, Martínez-Bilbao C, Dourdil V, Ramírez-Payer Á, Sarrá J, Cibeira MT
Amyloid 2020 Sep;27(3):163-167. Epub 2020 Feb 28 doi: 10.1080/13506129.2020.1730791. PMID: 32106714
Kastritis E, Gavriatopoulou M, Roussou M, Bagratuni T, Migkou M, Fotiou D, Ziogas DC, Kanellias N, Eleutherakis-Papaiakovou E, Dialoupi I, Ntanasis-Stathopoulos I, Spyropoulou-Vlachou M, Psimenou E, Gakiopoulou H, Marinaki S, Papadopoulou E, Ntalianis A, Terpos E, Dimopoulos MA
Amyloid 2018 Dec;25(4):234-241. Epub 2019 Jan 20 doi: 10.1080/13506129.2018.1540410. PMID: 30663408

Clinical prediction guides

Sanchorawala V, Wechalekar AD, Kim K, Schönland SO, Landau HJ, Kwok F, Suzuki K, Dispenzieri A, Merlini G, Comenzo RL, Cherepanov D, Hayden VC, Kumar A, Labotka R, Faller DV, Kastritis E
Am J Hematol 2023 May;98(5):720-729. Epub 2023 Feb 14 doi: 10.1002/ajh.26866. PMID: 36708469
Kfir-Erenfeld S, Asherie N, Grisariu S, Avni B, Zimran E, Assayag M, Sharon TD, Pick M, Lebel E, Shaulov A, Cohen YC, Avivi I, Cohen CJ, Stepensky P, Gatt ME
Clin Cancer Res 2022 Dec 1;28(23):5156-5166. doi: 10.1158/1078-0432.CCR-22-0637. PMID: 36107221
Shragai T, Gatt M, Lavie N, Vaxman I, Tadmor T, Rouvio O, Zektser M, Horowitz N, Magen H, Ballan M, Suru C, Luttwak E, Levi S, Ziv-Baran T, Avivi I, Cohen YC
Eur J Haematol 2021 Feb;106(2):184-195. Epub 2020 Nov 9 doi: 10.1111/ejh.13535. PMID: 33090552
Cohen OC, Brodermann MH, Blakeney IJ, Mahmood S, Sachchithanantham S, Ravichandran S, Law S, Lachmann HJ, Whelan CJ, Popat R, Rabin N, Yong K, Kyriakou C, Shah R, Cheesman S, Worthington S, Hawkins P, Gillmore JD, Wechalekar AD
Amyloid 2020 Sep;27(3):200-205. Epub 2020 May 15 doi: 10.1080/13506129.2020.1765768. PMID: 32408823
Milani P, Fazio F, Basset M, Berno T, Larocca A, Foli A, Riva M, Benigna F, Oliva S, Nuvolone M, Rodigari L, Petrucci MT, Merlini G, Palladini G
Am J Hematol 2020 Aug;95(8):900-905. Epub 2020 Apr 30 doi: 10.1002/ajh.25828. PMID: 32282971

Recent systematic reviews

Ehsan H, Rafae A, Masood A, Wahab A, Sana MK, Ansar I, Neupane K, Umar A, Ehsan A, Hashmi H
Clin Lymphoma Myeloma Leuk 2022 May;22(5):e285-e292. Epub 2021 Nov 1 doi: 10.1016/j.clml.2021.10.014. PMID: 34879994
Shragai T, Gatt M, Lavie N, Vaxman I, Tadmor T, Rouvio O, Zektser M, Horowitz N, Magen H, Ballan M, Suru C, Luttwak E, Levi S, Ziv-Baran T, Avivi I, Cohen YC
Eur J Haematol 2021 Feb;106(2):184-195. Epub 2020 Nov 9 doi: 10.1111/ejh.13535. PMID: 33090552

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