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Refractory Cervical Carcinoma

MedGen UID:
1749121
•Concept ID:
C5418595
•
Neoplastic Process

Definition

Cervical carcinoma that is resistant to treatment. [from NCI]

Professional guidelines

PubMed

Futibatinib, an Irreversible FGFR1-4 Inhibitor for the Treatment of FGFR-Aberrant Tumors.
Javle M, King G, Spencer K, Borad MJ
Oncologist 2023 Nov 2;28(11):928-943. doi: 10.1093/oncolo/oyad149. PMID: 37390492Free PMC Article
Camrelizumab and metronomic capecitabine for patients with treatment-refractory solid tumors (McCREST trial).
Zhou C, Shangguan C, Shi M, Xi W, Wu J, Yang H, Guo L, Cai Q, Shi Y, Liu J, Zhang J
Future Oncol 2022 Jul;18(23):2495-2503. Epub 2022 Jun 15 doi: 10.2217/fon-2021-1579. PMID: 35703115
Nivolumab vs Pembrolizumab for Treatment of US Patients With Platinum-Refractory Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Network Meta-analysis and Cost-effectiveness Analysis.
Pei R, Shi Y, Lv S, Dai T, Zhang F, Liu S, Wu B
JAMA Netw Open 2021 May 3;4(5):e218065. doi: 10.1001/jamanetworkopen.2021.8065. PMID: 33956130Free PMC Article

Recent clinical studies

Etiology

Cannabis-based medicines and medical cannabis for adults with cancer pain.
Häuser W, Welsch P, Radbruch L, Fisher E, Bell RF, Moore RA
Cochrane Database Syst Rev 2023 Jun 5;6(6):CD014915. doi: 10.1002/14651858.CD014915.pub2. PMID: 37283486Free PMC Article
Immunotherapy for recurrent/metastatic head and neck cancer.
Alfieri S, Cavalieri S, Licitra L
Curr Opin Otolaryngol Head Neck Surg 2018 Apr;26(2):152-156. doi: 10.1097/MOO.0000000000000448. PMID: 29432222
Role of Immunotherapy in Head and Neck Cancer.
Ling DC, Bakkenist CJ, Ferris RL, Clump DA
Semin Radiat Oncol 2018 Jan;28(1):12-16. doi: 10.1016/j.semradonc.2017.08.009. PMID: 29173750
Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck.
Ferris RL, Blumenschein G Jr, Fayette J, Guigay J, Colevas AD, Licitra L, Harrington K, Kasper S, Vokes EE, Even C, Worden F, Saba NF, Iglesias Docampo LC, Haddad R, Rordorf T, Kiyota N, Tahara M, Monga M, Lynch M, Geese WJ, Kopit J, Shaw JW, Gillison ML
N Engl J Med 2016 Nov 10;375(19):1856-1867. Epub 2016 Oct 8 doi: 10.1056/NEJMoa1602252. PMID: 27718784Free PMC Article
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
Fossella FV, DeVore R, Kerr RN, Crawford J, Natale RR, Dunphy F, Kalman L, Miller V, Lee JS, Moore M, Gandara D, Karp D, Vokes E, Kris M, Kim Y, Gamza F, Hammershaimb L
J Clin Oncol 2000 Jun;18(12):2354-62. doi: 10.1200/JCO.2000.18.12.2354. PMID: 10856094

Diagnosis

AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1(+) CD8 T cells.
Li H, Liu Z, Liu L, Zhang H, Han C, Girard L, Park H, Zhang A, Dong C, Ye J, Rayford A, Peyton M, Li X, Avila K, Cao X, Hu S, Alam MM, Akbay EA, Solis LM, Behrens C, Hernandez-Ruiz S, Lu W, Wistuba I, Heymach JV, Chisamore M, Micklem D, Gabra H, Gausdal G, Lorens JB, Li B, Fu YX, Minna JD, Brekken RA
Cell Rep Med 2022 Mar 15;3(3):100554. doi: 10.1016/j.xcrm.2022.100554. PMID: 35492873Free PMC Article
Role of Immunotherapy in Head and Neck Cancer.
Ling DC, Bakkenist CJ, Ferris RL, Clump DA
Semin Radiat Oncol 2018 Jan;28(1):12-16. doi: 10.1016/j.semradonc.2017.08.009. PMID: 29173750
Management of the lateral neck in well differentiated thyroid cancer.
Cracchiolo JR, Wong RJ
Eur J Surg Oncol 2018 Mar;44(3):332-337. Epub 2017 Jun 22 doi: 10.1016/j.ejso.2017.06.004. PMID: 28687430Free PMC Article
The prognostic implications from molecular testing of thyroid cancer.
Ozgursoy OB, Eisele DW, Tufano RP
Otolaryngol Clin North Am 2014 Aug;47(4):595-607. doi: 10.1016/j.otc.2014.04.010. PMID: 25041960
Emphasizing on heat shock protein 90's utility in head and neck squamous cell carcinoma treatment.
Routray S, Sunkavalli A, Swain N, Shankar AA
J Cancer Res Ther 2013 Oct-Dec;9(4):583-6. doi: 10.4103/0973-1482.126451. PMID: 24518700

Therapy

Clinical Pharmacology Profile of AMG 119, the First Chimeric Antigen Receptor T (CAR-T) Cell Therapy Targeting Delta-Like Ligand 3 (DLL3), in Patients with Relapsed/Refractory Small Cell Lung Cancer (SCLC).
Zhou D, Byers LA, Sable B, Smit MD, Sadraei NH, Dutta S, Upreti VV
J Clin Pharmacol 2024 Mar;64(3):362-370. Epub 2023 Oct 2 doi: 10.1002/jcph.2346. PMID: 37694295
Molecular mechanisms of resistance to kinase inhibitors and redifferentiation in thyroid cancers.
Hofmann MC, Kunnimalaiyaan M, Wang JR, Busaidy NL, Sherman SI, Lai SY, Zafereo M, Cabanillas ME
Endocr Relat Cancer 2022 Nov 1;29(11):R173-R190. Epub 2022 Sep 14 doi: 10.1530/ERC-22-0129. PMID: 35975971Free PMC Article
Zimberelimab: First Approval.
Markham A
Drugs 2021 Nov;81(17):2063-2068. doi: 10.1007/s40265-021-01628-5. PMID: 34709602
Copanlisib: First Global Approval.
Markham A
Drugs 2017 Dec;77(18):2057-2062. doi: 10.1007/s40265-017-0838-6. PMID: 29127587
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non-Small Cell Lung Cancer Study Group.
Fossella FV, DeVore R, Kerr RN, Crawford J, Natale RR, Dunphy F, Kalman L, Miller V, Lee JS, Moore M, Gandara D, Karp D, Vokes E, Kris M, Kim Y, Gamza F, Hammershaimb L
J Clin Oncol 2000 Jun;18(12):2354-62. doi: 10.1200/JCO.2000.18.12.2354. PMID: 10856094

Prognosis

Pathogenesis and signaling pathways related to iodine-refractory differentiated thyroid cancer.
Zhao S, Zhao Y, Zhao Y, Wang G
Front Endocrinol (Lausanne) 2023;14:1320044. Epub 2024 Jan 19 doi: 10.3389/fendo.2023.1320044. PMID: 38313845Free PMC Article
Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma.
Pu W, Shi X, Yu P, Zhang M, Liu Z, Tan L, Han P, Wang Y, Ji D, Gan H, Wei W, Lu Z, Qu N, Hu J, Hu X, Luo Z, Li H, Ji Q, Wang J, Zhang X, Wang YL
Nat Commun 2021 Oct 18;12(1):6058. doi: 10.1038/s41467-021-26343-3. PMID: 34663816Free PMC Article
The 5-Ws of immunotherapy in head and neck cancer.
Botticelli A, Mezi S, Pomati G, Cerbelli B, Di Rocco C, Amirhassankhani S, Sirgiovanni G, Occhipinti M, Napoli V, Emiliani A, Mazzuca F, Tomao S, Nuti M, Marchetti P
Crit Rev Oncol Hematol 2020 Sep;153:103041. Epub 2020 Jun 30 doi: 10.1016/j.critrevonc.2020.103041. PMID: 32629362
Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck.
Ferris RL, Blumenschein G Jr, Fayette J, Guigay J, Colevas AD, Licitra L, Harrington K, Kasper S, Vokes EE, Even C, Worden F, Saba NF, Iglesias Docampo LC, Haddad R, Rordorf T, Kiyota N, Tahara M, Monga M, Lynch M, Geese WJ, Kopit J, Shaw JW, Gillison ML
N Engl J Med 2016 Nov 10;375(19):1856-1867. Epub 2016 Oct 8 doi: 10.1056/NEJMoa1602252. PMID: 27718784Free PMC Article
Nasopharyngeal carcinoma: the next challenges.
Razak AR, Siu LL, Liu FF, Ito E, O'Sullivan B, Chan K
Eur J Cancer 2010 Jul;46(11):1967-78. Epub 2010 May 5 doi: 10.1016/j.ejca.2010.04.004. PMID: 20451372

Clinical prediction guides

Tumor-Derived RAB21+ABHD12+ sEVs Drive the Premetastatic Microenvironment in the Lung.
Wu K, Li Y, Ji Y, Liu C, Wang X, Guo H, Zhang J, He Y
Cancer Immunol Res 2024 Feb 2;12(2):161-179. doi: 10.1158/2326-6066.CIR-23-0221. PMID: 38215051
Radioactive Iodine in Differentiated Thyroid Carcinoma: A Systematic AGREE II Clinical Practice Guideline Appraisal.
Monos S, Fritz C, Harris J, Romeo D, Ng JJ, Xu K, Cooperberg B, Moreira A, Rajasekaran K
Otolaryngol Head Neck Surg 2024 Jan;170(1):20-33. Epub 2023 Sep 11 doi: 10.1002/ohn.508. PMID: 37694597
AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1(+) CD8 T cells.
Li H, Liu Z, Liu L, Zhang H, Han C, Girard L, Park H, Zhang A, Dong C, Ye J, Rayford A, Peyton M, Li X, Avila K, Cao X, Hu S, Alam MM, Akbay EA, Solis LM, Behrens C, Hernandez-Ruiz S, Lu W, Wistuba I, Heymach JV, Chisamore M, Micklem D, Gabra H, Gausdal G, Lorens JB, Li B, Fu YX, Minna JD, Brekken RA
Cell Rep Med 2022 Mar 15;3(3):100554. doi: 10.1016/j.xcrm.2022.100554. PMID: 35492873Free PMC Article
The prognostic implications from molecular testing of thyroid cancer.
Ozgursoy OB, Eisele DW, Tufano RP
Otolaryngol Clin North Am 2014 Aug;47(4):595-607. doi: 10.1016/j.otc.2014.04.010. PMID: 25041960
Nasopharyngeal carcinoma: the next challenges.
Razak AR, Siu LL, Liu FF, Ito E, O'Sullivan B, Chan K
Eur J Cancer 2010 Jul;46(11):1967-78. Epub 2010 May 5 doi: 10.1016/j.ejca.2010.04.004. PMID: 20451372

Recent systematic reviews

A systematic review of antibody-drug conjugates and bispecific antibodies in head and neck squamous cell carcinoma and nasopharyngeal carcinoma: Charting the course of future therapies.
Jiménez-Labaig P, Rullan A, Hernando-Calvo A, Llop S, Bhide S, O'Leary B, Braña I, Harrington KJ
Cancer Treat Rev 2024 Jul;128:102772. Epub 2024 May 26 doi: 10.1016/j.ctrv.2024.102772. PMID: 38820656
Radioactive Iodine in Differentiated Thyroid Carcinoma: A Systematic AGREE II Clinical Practice Guideline Appraisal.
Monos S, Fritz C, Harris J, Romeo D, Ng JJ, Xu K, Cooperberg B, Moreira A, Rajasekaran K
Otolaryngol Head Neck Surg 2024 Jan;170(1):20-33. Epub 2023 Sep 11 doi: 10.1002/ohn.508. PMID: 37694597
Cannabis-based medicines and medical cannabis for adults with cancer pain.
Häuser W, Welsch P, Radbruch L, Fisher E, Bell RF, Moore RA
Cochrane Database Syst Rev 2023 Jun 5;6(6):CD014915. doi: 10.1002/14651858.CD014915.pub2. PMID: 37283486Free PMC Article
Anti-PD-1 and Anti-PD-L1 in Head and Neck Cancer: A Network Meta-Analysis.
Botticelli A, Cirillo A, Strigari L, Valentini F, Cerbelli B, Scagnoli S, Cerbelli E, Zizzari IG, Rocca CD, D'Amati G, Polimeni A, Nuti M, Merlano MC, Mezi S, Marchetti P
Front Immunol 2021;12:705096. Epub 2021 Aug 9 doi: 10.3389/fimmu.2021.705096. PMID: 34434192Free PMC Article
Chemotherapy and immunotherapy for recurrent and metastatic head and neck cancer: a systematic review.
Guidi A, Codecà C, Ferrari D
Med Oncol 2018 Feb 13;35(3):37. doi: 10.1007/s12032-018-1096-5. PMID: 29441454

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