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Chromophobe adenoma

MedGen UID:
1747
•Concept ID:
C0001432
•
Neoplastic Process
Synonyms: Adenoma, Chromophobe; Adenomas, Chromophobe; Chromophobe Adenoma; Chromophobe Adenomas
SNOMED CT: Chromophobe adenoma (37039006)
 
Monarch Initiative: MONDO:0006701

Definition

An epithelial neoplasm of the anterior pituitary gland in which the neoplastic cells do not stain with acidic or basic dyes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChromophobe adenoma

Professional guidelines

PubMed

Long-term results of radiotherapy in the treatment of pituitary adenomas in children and adolescents.
Grigsby PW, Thomas PR, Simpson JR, Fineberg BB
Am J Clin Oncol 1988 Dec;11(6):607-11. doi: 10.1097/00000421-198812000-00001. PMID: 3189225
Superiority of bromocriptine over pyridoxine in the treatment of patients with acromegaly or galactorrhea.
Blum I, Segal S, Kaufman H, Sagiv M, Shalit M, Chowers I
Isr J Med Sci 1980 Jan;16(1):12-6. PMID: 7188934
Chromophobe adenoma: evaluation and management.
Kenan PD, Hudson WR
Trans Am Acad Ophthalmol Otolaryngol 1969 Jan-Feb;73(1):52-9. PMID: 5768706

Recent clinical studies

Etiology

Natural history of pituitary apoplexy: a long-term follow-up study.
Shaikh AA, Williams DM, Stephens JW, Boregowda K, Udiawar MV, Price DE
Postgrad Med J 2023 Jun 15;99(1172):595-598. doi: 10.1136/postgradmedj-2022-141836. PMID: 37319160
Origin of renal cell carcinomas.
Valladares Ayerbes M, Aparicio Gallego G, Díaz Prado S, Jiménez Fonseca P, García Campelo R, Antón Aparicio LM
Clin Transl Oncol 2008 Nov;10(11):697-712. doi: 10.1007/s12094-008-0276-8. PMID: 19015066
Histopathology of the pituitary.
Doniach I
Clin Endocrinol Metab 1985 Nov;14(4):765-89. doi: 10.1016/s0300-595x(85)80077-3. PMID: 3002676
Optic chiasmal radionecrosis.
Hammer HM
Trans Ophthalmol Soc U K (1962) 1983;103 ( Pt 2):208-11. PMID: 6582675
Hyperprolactinaemia and impotence.
Franks S, Jacobs HS, Martin N, Nabarro JD
Clin Endocrinol (Oxf) 1978 Apr;8(4):277-87. doi: 10.1111/j.1365-2265.1978.tb02770.x. PMID: 647983

Diagnosis

Natural history of pituitary apoplexy: a long-term follow-up study.
Shaikh AA, Williams DM, Stephens JW, Boregowda K, Udiawar MV, Price DE
Postgrad Med J 2023 Jun 15;99(1172):595-598. doi: 10.1136/postgradmedj-2022-141836. PMID: 37319160
Characterizing Indeterminate Renal Masses with Molecular Imaging: the Role of (99m)Tc-MIBI SPECT/CT.
Reynolds AM, Porter KK
Curr Urol Rep 2017 Sep 12;18(11):86. doi: 10.1007/s11934-017-0737-0. PMID: 28900880
Pituitary prolactinomas.
Nabarro JD
Clin Endocrinol (Oxf) 1982 Aug;17(2):129-55. doi: 10.1111/j.1365-2265.1982.tb01573.x. PMID: 6751612
SEE-SAW NYSTAGMUS.
DAROFF RB
Neurology 1965 Sep;15:874-7. doi: 10.1212/wnl.15.9.874. PMID: 14334964
SEE-SAW NYSTAGMUS.
SCHURR PH
Proc R Soc Med 1963 Sep;56(9):808-10. PMID: 14080077Free PMC Article

Therapy

Normal and abnormal function of the hypothalamic-pituitary-adrenocortical system in man.
Streeten DH, Anderson GH Jr, Dalakos TG, Seeley D, Mallov JS, Eusebio R, Sunderlin FS, Badawy SZ, King RB
Endocr Rev 1984 Summer;5(3):371-94. doi: 10.1210/edrv-5-3-371. PMID: 6088218
Pituitary prolactinomas.
Nabarro JD
Clin Endocrinol (Oxf) 1982 Aug;17(2):129-55. doi: 10.1111/j.1365-2265.1982.tb01573.x. PMID: 6751612
Juxtasellar hyperostosis of non-meningiomatous origin.
Lee KF, Whiteley WH 3rd, Schatz NJ, Edeiken J, Lin SR, Tsai FY
J Neurosurg 1976 May;44(5):571-9. doi: 10.3171/jns.1976.44.5.0571. PMID: 772178
Pituitary apoplexy.
Lopez IA
J Oslo City Hosp 1970 Feb;20(2):17-27. PMID: 4905958
AMENORRHEA AND GALACTORRHEA.
THOMPSON JP, KEMPERS RD
Am J Obstet Gynecol 1965 Sep 1;93:65-71. doi: 10.1016/0002-9378(65)90295-4. PMID: 14330572

Prognosis

Natural history of pituitary apoplexy: a long-term follow-up study.
Shaikh AA, Williams DM, Stephens JW, Boregowda K, Udiawar MV, Price DE
Postgrad Med J 2023 Jun 15;99(1172):595-598. doi: 10.1136/postgradmedj-2022-141836. PMID: 37319160
VEGF, VEGF165b and EG-VEGF expression is specifically related with hormone profile in pituitary adenomas.
Corlan AS, Cîmpean AM, Melnic E, Raica M, Sarb S
Eur J Histochem 2019 Mar 5;63(1) doi: 10.4081/ejh.2019.3010. PMID: 30838843Free PMC Article
Review of renal oncocytoma with focus on clinical and pathobiological aspects.
Kuroda N, Toi M, Hiroi M, Shuin T, Enzan H
Histol Histopathol 2003 Jul;18(3):935-42. doi: 10.14670/HH-18.935. PMID: 12792905
Optic chiasmal radionecrosis.
Hammer HM
Trans Ophthalmol Soc U K (1962) 1983;103 ( Pt 2):208-11. PMID: 6582675
AMENORRHEA AND GALACTORRHEA.
THOMPSON JP, KEMPERS RD
Am J Obstet Gynecol 1965 Sep 1;93:65-71. doi: 10.1016/0002-9378(65)90295-4. PMID: 14330572

Clinical prediction guides

Origin of renal cell carcinomas.
Valladares Ayerbes M, Aparicio Gallego G, Díaz Prado S, Jiménez Fonseca P, García Campelo R, Antón Aparicio LM
Clin Transl Oncol 2008 Nov;10(11):697-712. doi: 10.1007/s12094-008-0276-8. PMID: 19015066
Histologic coagulative tumor necrosis as a prognostic indicator of renal cell carcinoma aggressiveness.
Sengupta S, Lohse CM, Leibovich BC, Frank I, Thompson RH, Webster WS, Zincke H, Blute ML, Cheville JC, Kwon ED
Cancer 2005 Aug 1;104(3):511-20. doi: 10.1002/cncr.21206. PMID: 15973740
Review of renal oncocytoma with focus on clinical and pathobiological aspects.
Kuroda N, Toi M, Hiroi M, Shuin T, Enzan H
Histol Histopathol 2003 Jul;18(3):935-42. doi: 10.14670/HH-18.935. PMID: 12792905
Pituitary tumours.
Agarwal A, Mahapatra AK, Sharma MC
Indian J Pediatr 1998 Jan-Feb;65(1):107-14. doi: 10.1007/BF02849701. PMID: 10771953
Optic chiasmal radionecrosis.
Hammer HM
Trans Ophthalmol Soc U K (1962) 1983;103 ( Pt 2):208-11. PMID: 6582675

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