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Abnormal pharynx physiology

MedGen UID:
1742792
•Concept ID:
C5421643
•
Finding
HPO: HP:0033152

Definition

A functional anomaly of the pharynx. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal pharynx physiology

Professional guidelines

PubMed

Practical multidisciplinary framework for the assessment and management of patients with unexplained chronic aerodigestive symptoms.
Quigley N, Mistry SG, Vasant DH, Vasani S
BMJ Open Gastroenterol 2023 Nov 23;10(1) doi: 10.1136/bmjgast-2022-000883. PMID: 37996120Free PMC Article
Nasometry, videofluoroscopy, and the speech pathologist's evaluation and treatment.
de Stadler M, Hersh C
Adv Otorhinolaryngol 2015;76:7-17. Epub 2015 Feb 12 doi: 10.1159/000368004. PMID: 25733227
Management of velopharyngeal competence.
Senders CW
Facial Plast Surg Clin North Am 2001 Feb;9(1):27-35. PMID: 11465004

Recent clinical studies

Etiology

Craniofacial and upper airway morphology in adult obstructive sleep apnea patients: A systematic review and meta-analysis of cephalometric studies.
Neelapu BC, Kharbanda OP, Sardana HK, Balachandran R, Sardana V, Kapoor P, Gupta A, Vasamsetti S
Sleep Med Rev 2017 Feb;31:79-90. Epub 2016 Jan 30 doi: 10.1016/j.smrv.2016.01.007. PMID: 27039222
Normal and abnormal physiology, pharmacology, and anatomy of the gastroesophageal junction high-pressure zone.
Miller L, Vegesna A, Ruggieri M, Braverman A
Ann N Y Acad Sci 2016 Sep;1380(1):48-57. Epub 2016 Jul 28 doi: 10.1111/nyas.13168. PMID: 27467321
Neurogenic [corrected] and oropharyngeal dysphagia.
Rofes L, Clavé P, Ouyang A, Scharitzer M, Pokieser P, Vilardell N, Ortega O
Ann N Y Acad Sci 2013 Oct;1300:1-10. doi: 10.1111/nyas.12234. PMID: 24117630
Pharyngoesophageal pH monitoring.
Bardan E
Am J Med 2003 Aug 18;115 Suppl 3A:78S-80S. doi: 10.1016/s0002-9343(03)00202-x. PMID: 12928080
Obstructive sleep apnoea.
Malhotra A, White DP
Lancet 2002 Jul 20;360(9328):237-45. doi: 10.1016/S0140-6736(02)09464-3. PMID: 12133673

Diagnosis

Craniofacial and upper airway morphology in adult obstructive sleep apnea patients: A systematic review and meta-analysis of cephalometric studies.
Neelapu BC, Kharbanda OP, Sardana HK, Balachandran R, Sardana V, Kapoor P, Gupta A, Vasamsetti S
Sleep Med Rev 2017 Feb;31:79-90. Epub 2016 Jan 30 doi: 10.1016/j.smrv.2016.01.007. PMID: 27039222
Surgical speech disorders.
Shen T, Sie KC
Facial Plast Surg Clin North Am 2014 Nov;22(4):593-609. Epub 2014 Nov 8 doi: 10.1016/j.fsc.2014.07.010. PMID: 25444731
Pharyngoesophageal pH monitoring.
Bardan E
Am J Med 2003 Aug 18;115 Suppl 3A:78S-80S. doi: 10.1016/s0002-9343(03)00202-x. PMID: 12928080
Dysphagia: evaluation and treatment.
Logemann JA
Folia Phoniatr Logop 1995;47(3):140-64. doi: 10.1159/000266348. PMID: 7640720
The obesity-hypoventilation syndrome.
Morgan EJ, Zwillich CW
West J Med 1978 Nov;129(5):387-93. PMID: 364840Free PMC Article

Therapy

A bleeding throat.
Tuang GJ, Liman ARUA, Ramasundram S
Emerg Med J 2020 Feb;37(2):72-101. doi: 10.1136/emermed-2019-209119. PMID: 31980549
Normal and abnormal physiology, pharmacology, and anatomy of the gastroesophageal junction high-pressure zone.
Miller L, Vegesna A, Ruggieri M, Braverman A
Ann N Y Acad Sci 2016 Sep;1380(1):48-57. Epub 2016 Jul 28 doi: 10.1111/nyas.13168. PMID: 27467321
Palate re-repair revisited.
Sommerlad BC, Mehendale FV, Birch MJ, Sell D, Hattee C, Harland K
Cleft Palate Craniofac J 2002 May;39(3):295-307. doi: 10.1597/1545-1569_2002_039_0295_prrr_2.0.co_2. PMID: 12019005
Partial adenoidectomy.
Shapiro RS
Laryngoscope 1982 Feb;92(2):135-9. doi: 10.1002/lary.1982.92.2.135. PMID: 7162308
The obesity-hypoventilation syndrome.
Morgan EJ, Zwillich CW
West J Med 1978 Nov;129(5):387-93. PMID: 364840Free PMC Article

Prognosis

Phenotyping OSAH patients during wakefulness.
Pini L, Magri R, Perger E, Levi G, Zambelli L, Giordani J, Ciarfaglia M, Tantucci C
Sleep Breath 2022 Dec;26(4):1801-1807. Epub 2022 Jan 13 doi: 10.1007/s11325-021-02551-5. PMID: 35023036
Steinert syndrome and repercussions in dental medicine.
Baptista H, Lopes Cardoso I
Arch Oral Biol 2017 Mar;75:37-47. Epub 2016 Dec 23 doi: 10.1016/j.archoralbio.2016.12.008. PMID: 28040606
Obstructive sleep apnea in infants.
Katz ES, Mitchell RB, D'Ambrosio CM
Am J Respir Crit Care Med 2012 Apr 15;185(8):805-16. Epub 2011 Dec 1 doi: 10.1164/rccm.201108-1455CI. PMID: 22135346Free PMC Article
Guillain-Barré syndrome.
Gurwood AS, Drake J
Optometry 2006 Nov;77(11):540-6. doi: 10.1016/j.optm.2006.06.014. PMID: 17145565
Palate re-repair revisited.
Sommerlad BC, Mehendale FV, Birch MJ, Sell D, Hattee C, Harland K
Cleft Palate Craniofac J 2002 May;39(3):295-307. doi: 10.1597/1545-1569_2002_039_0295_prrr_2.0.co_2. PMID: 12019005

Clinical prediction guides

DNA Methylation as a Diagnostic, Prognostic, and Predictive Biomarker in Head and Neck Cancer.
Liouta G, Adamaki M, Tsintarakis A, Zoumpourlis P, Liouta A, Agelaki S, Zoumpourlis V
Int J Mol Sci 2023 Feb 3;24(3) doi: 10.3390/ijms24032996. PMID: 36769317Free PMC Article
Phenotyping OSAH patients during wakefulness.
Pini L, Magri R, Perger E, Levi G, Zambelli L, Giordani J, Ciarfaglia M, Tantucci C
Sleep Breath 2022 Dec;26(4):1801-1807. Epub 2022 Jan 13 doi: 10.1007/s11325-021-02551-5. PMID: 35023036
Nasometry, videofluoroscopy, and the speech pathologist's evaluation and treatment.
de Stadler M, Hersh C
Adv Otorhinolaryngol 2015;76:7-17. Epub 2015 Feb 12 doi: 10.1159/000368004. PMID: 25733227
Palate re-repair revisited.
Sommerlad BC, Mehendale FV, Birch MJ, Sell D, Hattee C, Harland K
Cleft Palate Craniofac J 2002 May;39(3):295-307. doi: 10.1597/1545-1569_2002_039_0295_prrr_2.0.co_2. PMID: 12019005
Hiccups: causes and cures.
Lewis JH
J Clin Gastroenterol 1985 Dec;7(6):539-52. doi: 10.1097/00004836-198512000-00021. PMID: 2868032

Recent systematic reviews

Effect of oropharyngeal colostrum therapy on neonatal sepsis in preterm neonates: A systematic review and meta-analysis.
Anne RP, Kumar J, Kumar P, Meena J
J Pediatr Gastroenterol Nutr 2024 Mar;78(3):471-487. Epub 2023 Dec 11 doi: 10.1002/jpn3.12085. PMID: 38314925
Effects of maxillary protraction appliances on airway dimensions in growing class III maxillary retrognathic patients: A systematic review and meta-analysis.
Ming Y, Hu Y, Li Y, Yu J, He H, Zheng L
Int J Pediatr Otorhinolaryngol 2018 Feb;105:138-145. Epub 2017 Dec 14 doi: 10.1016/j.ijporl.2017.12.013. PMID: 29447802
Craniofacial and upper airway morphology in adult obstructive sleep apnea patients: A systematic review and meta-analysis of cephalometric studies.
Neelapu BC, Kharbanda OP, Sardana HK, Balachandran R, Sardana V, Kapoor P, Gupta A, Vasamsetti S
Sleep Med Rev 2017 Feb;31:79-90. Epub 2016 Jan 30 doi: 10.1016/j.smrv.2016.01.007. PMID: 27039222
Physiological factors related to aspiration risk: a systematic review.
Steele CM, Cichero JA
Dysphagia 2014 Jun;29(3):295-304. Epub 2014 Feb 23 doi: 10.1007/s00455-014-9516-y. PMID: 24562507Free PMC Article
Effectiveness of nasopharyngoscopic biofeedback in clients with cleft palate speech: a systematic review.
Neumann S, Romonath R
Logoped Phoniatr Vocol 2012 Oct;37(3):95-106. Epub 2011 Dec 7 doi: 10.3109/14015439.2011.638669. PMID: 22145632

Supplemental Content

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