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Primary Middle Ear Meningioma

MedGen UID:
1729907
•Concept ID:
C5420537
•
Neoplastic Process

Definition

A rare extracranial meningioma that arises from the middle ear. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPrimary Middle Ear Meningioma

Professional guidelines

PubMed

Long-term efficacy of fractionated conformal radiotherapy for the management of primary optic nerve sheath meningioma.
Pandit R, Paris L, Rudich DS, Lesser RL, Kupersmith MJ, Miller NR
Br J Ophthalmol 2019 Oct;103(10):1436-1440. Epub 2018 Dec 20 doi: 10.1136/bjophthalmol-2018-313135. PMID: 30573496
Treatment-related secondary cancer in malignant meningiomas: a population-based study.
Bao X, Cao L, Piao H, Xie L
J Cancer Res Clin Oncol 2014 Apr;140(4):583-8. Epub 2014 Feb 8 doi: 10.1007/s00432-013-1493-2. PMID: 24509624

Recent clinical studies

Etiology

Orbital resection by intranasal technique (ORBIT): A new classification system for reporting endoscopically resectable primary benign orbital tumors.
Jafari A, Adappa ND, Anagnos VJ, Campbell RG, Castelnuovo P, Chalian A, Chambers CB, Chitguppi C, Dallan I, El Rassi E, Freitag SK, Fernandez Miranda JC, Ferreira M Jr, Gardner PA, Gudis DA, Harvey RJ, Huang Q, Humphreys IM, Kennedy DW, Lee JYK, Lehmann AE, Locatelli D, McKinney KA, Moreau A, Nyquist G, Palmer JN, Prepageran N, Pribitkin EA, Rabinowitz MR, Rosen MR, Sacks R, Sharma D, Snyderman CH, Tonya Stefko S, Stokken JK, Wang EW, Workman AD, Wu AW, Yu JY, Zhang MM, Zhou B, Bleier BS
Int Forum Allergy Rhinol 2023 Oct;13(10):1852-1863. Epub 2023 Mar 2 doi: 10.1002/alr.23141. PMID: 36808854
Laryngeal Manifestations of Neurofibromatosis.
Naunheim MR, Plotkin SR, Franco RA, Song PC
Otolaryngol Head Neck Surg 2016 Mar;154(3):494-7. Epub 2016 Jan 19 doi: 10.1177/0194599815626133. PMID: 26786267
Treatment-related secondary cancer in malignant meningiomas: a population-based study.
Bao X, Cao L, Piao H, Xie L
J Cancer Res Clin Oncol 2014 Apr;140(4):583-8. Epub 2014 Feb 8 doi: 10.1007/s00432-013-1493-2. PMID: 24509624
Cytopathology of extracranial ectopic and metastatic meningiomas.
Ocque R, Khalbuss WE, Monaco SE, Michelow PM, Pantanowitz L
Acta Cytol 2014;58(1):1-8. Epub 2013 Nov 1 doi: 10.1159/000355284. PMID: 24192779
Primary jugular foramen meningioma: imaging appearance and differentiating features.
Macdonald AJ, Salzman KL, Harnsberger HR, Gilbert E, Shelton C
AJR Am J Roentgenol 2004 Feb;182(2):373-7. doi: 10.2214/ajr.182.2.1820373. PMID: 14736665

Diagnosis

Primary Middle Ear Meningioma with Intact Tympanic Membrane: A Case Report and Literature Review.
Liu YJ, Han L, Cao J, Zheng HW, Yu LS
Ear Nose Throat J 2024 Jun;103(6):364-369. Epub 2021 Nov 17 doi: 10.1177/01455613211058100. PMID: 34784773
Primary extradural meningiomas in head: a report of 19 cases and review of literature.
Liu Y, Wang H, Shao H, Wang C
Int J Clin Exp Pathol 2015;8(5):5624-32. Epub 2015 May 1 PMID: 26191274Free PMC Article
Hypertrophic pachymeningitis.
Dziedzic T, Wojciechowski J, Nowak A, Marchel A
Childs Nerv Syst 2015 Jul;31(7):1025-31. Epub 2015 Mar 15 doi: 10.1007/s00381-015-2680-z. PMID: 25771924
Cytopathology of extracranial ectopic and metastatic meningiomas.
Ocque R, Khalbuss WE, Monaco SE, Michelow PM, Pantanowitz L
Acta Cytol 2014;58(1):1-8. Epub 2013 Nov 1 doi: 10.1159/000355284. PMID: 24192779
Primary jugular foramen meningioma: imaging appearance and differentiating features.
Macdonald AJ, Salzman KL, Harnsberger HR, Gilbert E, Shelton C
AJR Am J Roentgenol 2004 Feb;182(2):373-7. doi: 10.2214/ajr.182.2.1820373. PMID: 14736665

Therapy

A phase 1 trial of the histone deacetylase inhibitor AR-42 in patients with neurofibromatosis type 2-associated tumors and advanced solid malignancies.
Collier KA, Valencia H, Newton H, Hade EM, Sborov DW, Cavaliere R, Poi M, Phelps MA, Liva SG, Coss CC, Wang J, Khountham S, Monk P, Shapiro CL, Piekarz R, Hofmeister CC, Welling DB, Mortazavi A
Cancer Chemother Pharmacol 2021 May;87(5):599-611. Epub 2021 Jan 25 doi: 10.1007/s00280-020-04229-3. PMID: 33492438Free PMC Article
Convexity Meningiomas in Patients with Neurofibromatosis Type 2: Long-Term Outcomes After Gamma Knife Radiosurgery.
Ruiz-Garcia H, Trifiletti DM, Mohammed N, Hung YC, Xu Z, Chytka T, Liscak R, Tripathi M, Arsanious D, Cifarelli CP, Caceres MP, Mathieu D, Speckter H, Lekovic GP, Mehta GU, Sheehan JP
World Neurosurg 2021 Feb;146:e678-e684. Epub 2020 Nov 3 doi: 10.1016/j.wneu.2020.10.153. PMID: 33152493Free PMC Article
Prospective, Randomized Study of Radiation Dose Escalation With Combined Proton-Photon Therapy for Benign Meningiomas.
Sanford NN, Yeap BY, Larvie M, Daartz J, Munzenrider JE, Liebsch NJ, Fullerton B, Pan E, Loeffler JS, Shih HA
Int J Radiat Oncol Biol Phys 2017 Nov 15;99(4):787-796. Epub 2017 Jul 12 doi: 10.1016/j.ijrobp.2017.07.008. PMID: 28865924Free PMC Article
Atypical central nervous system lymphoma at the cranial base: report of four cases.
Roman-Goldstein SM, Jones A, Delashaw JB, McMenomey S, Neuwelt EA
Neurosurgery 1998 Sep;43(3):613-5; discussion 615-6. doi: 10.1097/00006123-199809000-00119. PMID: 9733317

Prognosis

Orbital resection by intranasal technique (ORBIT): A new classification system for reporting endoscopically resectable primary benign orbital tumors.
Jafari A, Adappa ND, Anagnos VJ, Campbell RG, Castelnuovo P, Chalian A, Chambers CB, Chitguppi C, Dallan I, El Rassi E, Freitag SK, Fernandez Miranda JC, Ferreira M Jr, Gardner PA, Gudis DA, Harvey RJ, Huang Q, Humphreys IM, Kennedy DW, Lee JYK, Lehmann AE, Locatelli D, McKinney KA, Moreau A, Nyquist G, Palmer JN, Prepageran N, Pribitkin EA, Rabinowitz MR, Rosen MR, Sacks R, Sharma D, Snyderman CH, Tonya Stefko S, Stokken JK, Wang EW, Workman AD, Wu AW, Yu JY, Zhang MM, Zhou B, Bleier BS
Int Forum Allergy Rhinol 2023 Oct;13(10):1852-1863. Epub 2023 Mar 2 doi: 10.1002/alr.23141. PMID: 36808854
Primary extradural meningiomas in head: a report of 19 cases and review of literature.
Liu Y, Wang H, Shao H, Wang C
Int J Clin Exp Pathol 2015;8(5):5624-32. Epub 2015 May 1 PMID: 26191274Free PMC Article
Treatment-related secondary cancer in malignant meningiomas: a population-based study.
Bao X, Cao L, Piao H, Xie L
J Cancer Res Clin Oncol 2014 Apr;140(4):583-8. Epub 2014 Feb 8 doi: 10.1007/s00432-013-1493-2. PMID: 24509624
Primary meningioma of the middle ear: case report.
George M, Ikonomidis C, Pusztaszeri M, Monnier P
J Laryngol Otol 2010 May;124(5):572-4. Epub 2009 Nov 23 doi: 10.1017/S0022215109991745. PMID: 19930750
Posterior petrous meningiomas: 82 cases.
Wu ZB, Yu CJ, Guan SS
J Neurosurg 2005 Feb;102(2):284-9. doi: 10.3171/jns.2005.102.2.0284. PMID: 15739556

Clinical prediction guides

Orbital resection by intranasal technique (ORBIT): A new classification system for reporting endoscopically resectable primary benign orbital tumors.
Jafari A, Adappa ND, Anagnos VJ, Campbell RG, Castelnuovo P, Chalian A, Chambers CB, Chitguppi C, Dallan I, El Rassi E, Freitag SK, Fernandez Miranda JC, Ferreira M Jr, Gardner PA, Gudis DA, Harvey RJ, Huang Q, Humphreys IM, Kennedy DW, Lee JYK, Lehmann AE, Locatelli D, McKinney KA, Moreau A, Nyquist G, Palmer JN, Prepageran N, Pribitkin EA, Rabinowitz MR, Rosen MR, Sacks R, Sharma D, Snyderman CH, Tonya Stefko S, Stokken JK, Wang EW, Workman AD, Wu AW, Yu JY, Zhang MM, Zhou B, Bleier BS
Int Forum Allergy Rhinol 2023 Oct;13(10):1852-1863. Epub 2023 Mar 2 doi: 10.1002/alr.23141. PMID: 36808854
Laryngeal Manifestations of Neurofibromatosis.
Naunheim MR, Plotkin SR, Franco RA, Song PC
Otolaryngol Head Neck Surg 2016 Mar;154(3):494-7. Epub 2016 Jan 19 doi: 10.1177/0194599815626133. PMID: 26786267
Hypertrophic pachymeningitis.
Dziedzic T, Wojciechowski J, Nowak A, Marchel A
Childs Nerv Syst 2015 Jul;31(7):1025-31. Epub 2015 Mar 15 doi: 10.1007/s00381-015-2680-z. PMID: 25771924
Leksell Gamma Knife radiosurgery of the jugulotympanic glomus tumor: long-term results.
Liscak R, Urgosik D, Chytka T, Simonova G, Novotny J Jr, Vymazal J, Guseynova K, Vladyka V
J Neurosurg 2014 Dec;121 Suppl:198-202. doi: 10.3171/2014.7.GKS14923. PMID: 25434953
Treatment-related secondary cancer in malignant meningiomas: a population-based study.
Bao X, Cao L, Piao H, Xie L
J Cancer Res Clin Oncol 2014 Apr;140(4):583-8. Epub 2014 Feb 8 doi: 10.1007/s00432-013-1493-2. PMID: 24509624

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