U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Locally Advanced Alveolar Soft Part Sarcoma

MedGen UID:
1715133
•Concept ID:
C5235949
•
Neoplastic Process

Definition

Alveolar soft part sarcoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Alveolar Soft Part Sarcoma

Professional guidelines

PubMed

The current management of alveolar soft part sarcomas.
Chang X, Li Y, Xue X, Zhou H, Hou L
Medicine (Baltimore) 2021 Aug 6;100(31):e26805. doi: 10.1097/MD.0000000000026805. PMID: 34397835Free PMC Article
Management of sarcomas in children, adolescents and adults: Interactions in two different age groups under the umbrellas of GSF-GETO and SFCE, with the support of the NETSARC+ network.
Bompas E, Martin V, Meniai F, Toulmonde M, Marec-Berard P, Claude L, Ducimetiere F, Chargari C, Minard-Colin V, Corradini N, Laurence V, Piperno-Neumann S, Defachelles AS, Bernier V, Italiano A, Orbach D, Blay JY, Gaspar N, Berlanga P
Bull Cancer 2021 Feb;108(2):163-176. Epub 2021 Jan 14 doi: 10.1016/j.bulcan.2020.10.009. PMID: 33455736

Recent clinical studies

Etiology

Pembrolizumab in patients with rare and ultra-rare sarcomas (AcSé Pembrolizumab): analysis of a subgroup from a non-randomised, open-label, phase 2, basket trial.
Blay JY, Chevret S, Le Cesne A, Brahmi M, Penel N, Cousin S, Bertucci F, Bompas E, Ryckewaert T, Soibinet P, Boudou-Rouquette P, Saada Bouzid E, Soulie P, Valentin T, Lotz JP, Tosi D, Neviere Z, Cancel M, Ray-Coquard I, Gambotti L, Legrand F, Lamrani-Ghaouti A, Simon C, Even C, Massard C
Lancet Oncol 2023 Aug;24(8):892-902. Epub 2023 Jul 7 doi: 10.1016/S1470-2045(23)00282-6. PMID: 37429302
Alveolar soft tissue sarcoma: a report of 50 cases at a single institution.
Zhao P, Li H, Ren H
Acta Chir Belg 2023 Aug;123(4):375-383. Epub 2022 Mar 12 doi: 10.1080/00015458.2022.2049060. PMID: 35236247
Alveolar soft part sarcoma: progress toward improvement in survival? A population-based study.
Fujiwara T, Nakata E, Kunisada T, Ozaki T, Kawai A
BMC Cancer 2022 Aug 15;22(1):891. doi: 10.1186/s12885-022-09968-5. PMID: 35971085Free PMC Article
Targeted and immuno-based therapies in sarcoma: mechanisms and advances in clinical trials.
Tang F, Tie Y, Wei YQ, Tu CQ, Wei XW
Biochim Biophys Acta Rev Cancer 2021 Dec;1876(2):188606. Epub 2021 Aug 8 doi: 10.1016/j.bbcan.2021.188606. PMID: 34371128
Management of sarcomas in children, adolescents and adults: Interactions in two different age groups under the umbrellas of GSF-GETO and SFCE, with the support of the NETSARC+ network.
Bompas E, Martin V, Meniai F, Toulmonde M, Marec-Berard P, Claude L, Ducimetiere F, Chargari C, Minard-Colin V, Corradini N, Laurence V, Piperno-Neumann S, Defachelles AS, Bernier V, Italiano A, Orbach D, Blay JY, Gaspar N, Berlanga P
Bull Cancer 2021 Feb;108(2):163-176. Epub 2021 Jan 14 doi: 10.1016/j.bulcan.2020.10.009. PMID: 33455736

Diagnosis

Alveolar soft tissue sarcoma: a report of 50 cases at a single institution.
Zhao P, Li H, Ren H
Acta Chir Belg 2023 Aug;123(4):375-383. Epub 2022 Mar 12 doi: 10.1080/00015458.2022.2049060. PMID: 35236247
Alveolar soft part sarcoma: progress toward improvement in survival? A population-based study.
Fujiwara T, Nakata E, Kunisada T, Ozaki T, Kawai A
BMC Cancer 2022 Aug 15;22(1):891. doi: 10.1186/s12885-022-09968-5. PMID: 35971085Free PMC Article
The current management of alveolar soft part sarcomas.
Chang X, Li Y, Xue X, Zhou H, Hou L
Medicine (Baltimore) 2021 Aug 6;100(31):e26805. doi: 10.1097/MD.0000000000026805. PMID: 34397835Free PMC Article
Management of sarcomas in children, adolescents and adults: Interactions in two different age groups under the umbrellas of GSF-GETO and SFCE, with the support of the NETSARC+ network.
Bompas E, Martin V, Meniai F, Toulmonde M, Marec-Berard P, Claude L, Ducimetiere F, Chargari C, Minard-Colin V, Corradini N, Laurence V, Piperno-Neumann S, Defachelles AS, Bernier V, Italiano A, Orbach D, Blay JY, Gaspar N, Berlanga P
Bull Cancer 2021 Feb;108(2):163-176. Epub 2021 Jan 14 doi: 10.1016/j.bulcan.2020.10.009. PMID: 33455736
Long-term results of therapy with sunitinib in metastatic alveolar soft part sarcoma.
Jagodzińska-Mucha P, Świtaj T, Kozak K, Koseła-Paterczyk H, Klimczak A, Ługowska I, Rogala P, Wągrodzki M, Falkowski S, Rutkowski P
Tumori 2017 May 12;103(3):231-235. Epub 2017 Mar 8 doi: 10.5301/tj.5000617. PMID: 28291905

Therapy

Pembrolizumab in patients with rare and ultra-rare sarcomas (AcSé Pembrolizumab): analysis of a subgroup from a non-randomised, open-label, phase 2, basket trial.
Blay JY, Chevret S, Le Cesne A, Brahmi M, Penel N, Cousin S, Bertucci F, Bompas E, Ryckewaert T, Soibinet P, Boudou-Rouquette P, Saada Bouzid E, Soulie P, Valentin T, Lotz JP, Tosi D, Neviere Z, Cancel M, Ray-Coquard I, Gambotti L, Legrand F, Lamrani-Ghaouti A, Simon C, Even C, Massard C
Lancet Oncol 2023 Aug;24(8):892-902. Epub 2023 Jul 7 doi: 10.1016/S1470-2045(23)00282-6. PMID: 37429302
Alveolar soft part sarcoma: progress toward improvement in survival? A population-based study.
Fujiwara T, Nakata E, Kunisada T, Ozaki T, Kawai A
BMC Cancer 2022 Aug 15;22(1):891. doi: 10.1186/s12885-022-09968-5. PMID: 35971085Free PMC Article
Targeted and immuno-based therapies in sarcoma: mechanisms and advances in clinical trials.
Tang F, Tie Y, Wei YQ, Tu CQ, Wei XW
Biochim Biophys Acta Rev Cancer 2021 Dec;1876(2):188606. Epub 2021 Aug 8 doi: 10.1016/j.bbcan.2021.188606. PMID: 34371128
Novel therapeutic options for alveolar soft part sarcoma: antiangiogenic therapy, immunotherapy and beyond.
Brahmi M, Vanacker H, Dufresne A
Curr Opin Oncol 2020 Jul;32(4):295-300. doi: 10.1097/CCO.0000000000000652. PMID: 32541316
Long-term results of therapy with sunitinib in metastatic alveolar soft part sarcoma.
Jagodzińska-Mucha P, Świtaj T, Kozak K, Koseła-Paterczyk H, Klimczak A, Ługowska I, Rogala P, Wągrodzki M, Falkowski S, Rutkowski P
Tumori 2017 May 12;103(3):231-235. Epub 2017 Mar 8 doi: 10.5301/tj.5000617. PMID: 28291905

Prognosis

Alveolar soft tissue sarcoma: a report of 50 cases at a single institution.
Zhao P, Li H, Ren H
Acta Chir Belg 2023 Aug;123(4):375-383. Epub 2022 Mar 12 doi: 10.1080/00015458.2022.2049060. PMID: 35236247
Alveolar soft part sarcoma: progress toward improvement in survival? A population-based study.
Fujiwara T, Nakata E, Kunisada T, Ozaki T, Kawai A
BMC Cancer 2022 Aug 15;22(1):891. doi: 10.1186/s12885-022-09968-5. PMID: 35971085Free PMC Article
A retrospective analysis of 14 consecutive Chinese patients with unresectable or metastatic alveolar soft part sarcoma treated with sunitinib.
Li T, Wang L, Wang H, Zhang S, Atikan Kawuli, Zhang X, Luo Z, Wang C
Invest New Drugs 2016 Dec;34(6):701-706. Epub 2016 Sep 8 doi: 10.1007/s10637-016-0390-3. PMID: 27604635

Clinical prediction guides

Alveolar soft tissue sarcoma: a report of 50 cases at a single institution.
Zhao P, Li H, Ren H
Acta Chir Belg 2023 Aug;123(4):375-383. Epub 2022 Mar 12 doi: 10.1080/00015458.2022.2049060. PMID: 35236247
Alveolar soft part sarcoma: progress toward improvement in survival? A population-based study.
Fujiwara T, Nakata E, Kunisada T, Ozaki T, Kawai A
BMC Cancer 2022 Aug 15;22(1):891. doi: 10.1186/s12885-022-09968-5. PMID: 35971085Free PMC Article
Review of renal carcinoma associated with Xp11.2 translocations/TFE3 gene fusions with focus on pathobiological aspect.
Kuroda N, Mikami S, Pan CC, Cohen RJ, Hes O, Michal M, Nagashima Y, Tanaka Y, Inoue K, Shuin T, Lee GH
Histol Histopathol 2012 Feb;27(2):133-40. doi: 10.14670/HH-27.133. PMID: 22207547

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...