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Refractory Skin Squamous Cell Carcinoma

MedGen UID:
1710593
Concept ID:
C5237413
Neoplastic Process

Definition

Skin squamous cell carcinoma that does not respond to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Skin Squamous Cell Carcinoma

Professional guidelines

PubMed

Kandolf L, Peris K, Malvehy J, Mosterd K, Heppt MV, Fargnoli MC, Berking C, Arenberger P, Bylaite-Bučinskiene M, Del Marmol V, Dirschka T, Dreno B, Forsea AM, Harwood CA, Hauschild A, Heerfordt IM, Kauffman R, Kelleners-Smeets N, Lallas A, Lebbe C, Leiter U, Longo C, Mijušković Ž, Pellacani G, Puig S, Saiag P, Šitum M, Stockfleth E, Salavastru C, Stratigos A, Zalaudek I, Garbe C; European Association of Dermato‐Oncology, European Dermatology Forum, European Academy of Dermatology and Venereology and Union of Medical Specialists (Union Européenne des Médecins Spécialistes)
J Eur Acad Dermatol Venereol 2024 Jun;38(6):1024-1047. Epub 2024 Mar 7 doi: 10.1111/jdv.19897. PMID: 38451047
Gellrich FF, Hüning S, Beissert S, Eigentler T, Stockfleth E, Gutzmer R, Meier F
J Eur Acad Dermatol Venereol 2019 Dec;33 Suppl 8:38-43. doi: 10.1111/jdv.16024. PMID: 31833610
Fistarol SK, Itin PH
Am J Clin Dermatol 2013 Feb;14(1):27-47. doi: 10.1007/s40257-012-0006-4. PMID: 23329078Free PMC Article

Recent clinical studies

Etiology

Kandolf L, Peris K, Malvehy J, Mosterd K, Heppt MV, Fargnoli MC, Berking C, Arenberger P, Bylaite-Bučinskiene M, Del Marmol V, Dirschka T, Dreno B, Forsea AM, Harwood CA, Hauschild A, Heerfordt IM, Kauffman R, Kelleners-Smeets N, Lallas A, Lebbe C, Leiter U, Longo C, Mijušković Ž, Pellacani G, Puig S, Saiag P, Šitum M, Stockfleth E, Salavastru C, Stratigos A, Zalaudek I, Garbe C; European Association of Dermato‐Oncology, European Dermatology Forum, European Academy of Dermatology and Venereology and Union of Medical Specialists (Union Européenne des Médecins Spécialistes)
J Eur Acad Dermatol Venereol 2024 Jun;38(6):1024-1047. Epub 2024 Mar 7 doi: 10.1111/jdv.19897. PMID: 38451047
Piernick Ii DM, Jahnke MN, Watson AC
Cutis 2019 Sep;104(3):E16-E18. PMID: 31675405
Ladizinski B, Alavi A, Jambrosic J, Mistry N, Sibbald RG
Adv Skin Wound Care 2014 Jul;27(7):301-9. doi: 10.1097/01.ASW.0000446864.26807.43. PMID: 24932950
Fistarol SK, Itin PH
Am J Clin Dermatol 2013 Feb;14(1):27-47. doi: 10.1007/s40257-012-0006-4. PMID: 23329078Free PMC Article
Kraut EH, Grever MR, Bouroncle BA
Blood 1994 Dec 15;84(12):4061-3. PMID: 7994024

Diagnosis

Kandolf L, Peris K, Malvehy J, Mosterd K, Heppt MV, Fargnoli MC, Berking C, Arenberger P, Bylaite-Bučinskiene M, Del Marmol V, Dirschka T, Dreno B, Forsea AM, Harwood CA, Hauschild A, Heerfordt IM, Kauffman R, Kelleners-Smeets N, Lallas A, Lebbe C, Leiter U, Longo C, Mijušković Ž, Pellacani G, Puig S, Saiag P, Šitum M, Stockfleth E, Salavastru C, Stratigos A, Zalaudek I, Garbe C; European Association of Dermato‐Oncology, European Dermatology Forum, European Academy of Dermatology and Venereology and Union of Medical Specialists (Union Européenne des Médecins Spécialistes)
J Eur Acad Dermatol Venereol 2024 Jun;38(6):1024-1047. Epub 2024 Mar 7 doi: 10.1111/jdv.19897. PMID: 38451047
Piernick Ii DM, Jahnke MN, Watson AC
Cutis 2019 Sep;104(3):E16-E18. PMID: 31675405
Ladizinski B, Alavi A, Jambrosic J, Mistry N, Sibbald RG
Adv Skin Wound Care 2014 Jul;27(7):301-9. doi: 10.1097/01.ASW.0000446864.26807.43. PMID: 24932950
Fistarol SK, Itin PH
Am J Clin Dermatol 2013 Feb;14(1):27-47. doi: 10.1007/s40257-012-0006-4. PMID: 23329078Free PMC Article
Yoo SS, Viglione M, Moresi M, Vonderheid E
J Dermatol 2003 May;30(5):417-9. doi: 10.1111/j.1346-8138.2003.tb00409.x. PMID: 12773809

Therapy

Kandolf L, Peris K, Malvehy J, Mosterd K, Heppt MV, Fargnoli MC, Berking C, Arenberger P, Bylaite-Bučinskiene M, Del Marmol V, Dirschka T, Dreno B, Forsea AM, Harwood CA, Hauschild A, Heerfordt IM, Kauffman R, Kelleners-Smeets N, Lallas A, Lebbe C, Leiter U, Longo C, Mijušković Ž, Pellacani G, Puig S, Saiag P, Šitum M, Stockfleth E, Salavastru C, Stratigos A, Zalaudek I, Garbe C; European Association of Dermato‐Oncology, European Dermatology Forum, European Academy of Dermatology and Venereology and Union of Medical Specialists (Union Européenne des Médecins Spécialistes)
J Eur Acad Dermatol Venereol 2024 Jun;38(6):1024-1047. Epub 2024 Mar 7 doi: 10.1111/jdv.19897. PMID: 38451047
Shalhout SZ, Emerick KS, Kaufman HL, Miller DM
Curr Oncol Rep 2021 Aug 27;23(11):125. doi: 10.1007/s11912-021-01120-z. PMID: 34448958Free PMC Article
Piernick Ii DM, Jahnke MN, Watson AC
Cutis 2019 Sep;104(3):E16-E18. PMID: 31675405
Gaide O, Clayton H, Girardin M, Kuonen F
Dermatology 2016;232 Suppl 1:7-8. Epub 2016 Aug 11 doi: 10.1159/000447388. PMID: 27513862
Fistarol SK, Itin PH
Am J Clin Dermatol 2013 Feb;14(1):27-47. doi: 10.1007/s40257-012-0006-4. PMID: 23329078Free PMC Article

Prognosis

Kandolf L, Peris K, Malvehy J, Mosterd K, Heppt MV, Fargnoli MC, Berking C, Arenberger P, Bylaite-Bučinskiene M, Del Marmol V, Dirschka T, Dreno B, Forsea AM, Harwood CA, Hauschild A, Heerfordt IM, Kauffman R, Kelleners-Smeets N, Lallas A, Lebbe C, Leiter U, Longo C, Mijušković Ž, Pellacani G, Puig S, Saiag P, Šitum M, Stockfleth E, Salavastru C, Stratigos A, Zalaudek I, Garbe C; European Association of Dermato‐Oncology, European Dermatology Forum, European Academy of Dermatology and Venereology and Union of Medical Specialists (Union Européenne des Médecins Spécialistes)
J Eur Acad Dermatol Venereol 2024 Jun;38(6):1024-1047. Epub 2024 Mar 7 doi: 10.1111/jdv.19897. PMID: 38451047
Ferrarotto R, Sousa LG, Qing Y, Kaya D, Stephen B, Jain D, Bell D, Pant S, Tsimberidou AM, Janku F, Blumenschein G, Glisson BS, Ahnert JR, Piha-Paul SA, Lee JJ, Wong MK, Lu C, Meric-Bernstam F, Naing A
Adv Ther 2021 Aug;38(8):4581-4591. Epub 2021 Jul 9 doi: 10.1007/s12325-021-01807-6. PMID: 34241781
Barrios DM, Do MH, Phillips GS, Postow MA, Akaike T, Nghiem P, Lacouture ME
J Am Acad Dermatol 2020 Nov;83(5):1239-1253. Epub 2020 May 24 doi: 10.1016/j.jaad.2020.03.131. PMID: 32461079Free PMC Article
Kraut EH, Grever MR, Bouroncle BA
Blood 1994 Dec 15;84(12):4061-3. PMID: 7994024
U R, Hiraoka M, Takahashi M, Abe M, Matsuda T, Sugiyama A, Nakada Y, Yamamoto I, Sugahara T
Med Instrum 1984 May-Jun;18(3):181-6. PMID: 6748997

Clinical prediction guides

Kandolf L, Peris K, Malvehy J, Mosterd K, Heppt MV, Fargnoli MC, Berking C, Arenberger P, Bylaite-Bučinskiene M, Del Marmol V, Dirschka T, Dreno B, Forsea AM, Harwood CA, Hauschild A, Heerfordt IM, Kauffman R, Kelleners-Smeets N, Lallas A, Lebbe C, Leiter U, Longo C, Mijušković Ž, Pellacani G, Puig S, Saiag P, Šitum M, Stockfleth E, Salavastru C, Stratigos A, Zalaudek I, Garbe C; European Association of Dermato‐Oncology, European Dermatology Forum, European Academy of Dermatology and Venereology and Union of Medical Specialists (Union Européenne des Médecins Spécialistes)
J Eur Acad Dermatol Venereol 2024 Jun;38(6):1024-1047. Epub 2024 Mar 7 doi: 10.1111/jdv.19897. PMID: 38451047
Yan Z, Liang P
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2022 Aug 28;47(8):1154-1162. doi: 10.11817/j.issn.1672-7347.2022.210332. PMID: 36097784Free PMC Article
Barrios DM, Do MH, Phillips GS, Postow MA, Akaike T, Nghiem P, Lacouture ME
J Am Acad Dermatol 2020 Nov;83(5):1239-1253. Epub 2020 May 24 doi: 10.1016/j.jaad.2020.03.131. PMID: 32461079Free PMC Article
Gatti V, Fierro C, Annicchiarico-Petruzzelli M, Melino G, Peschiaroli A
Mol Oncol 2019 May;13(5):981-1001. Epub 2019 Mar 22 doi: 10.1002/1878-0261.12473. PMID: 30845357Free PMC Article
Kraut EH, Grever MR, Bouroncle BA
Blood 1994 Dec 15;84(12):4061-3. PMID: 7994024

Recent systematic reviews

Abu Rached N, Rüth J, Gambichler T, Ocker L, Bechara FG
Ann Med 2024 Dec;56(1):2382372. Epub 2024 Jul 24 doi: 10.1080/07853890.2024.2382372. PMID: 39046819Free PMC Article
Seger EW, Tarantino IS, Neill BC, Wang T
J Cutan Med Surg 2020 Jan/Feb;24(1):41-46. Epub 2019 Oct 8 doi: 10.1177/1203475419882336. PMID: 31591899

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