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Locally Advanced Laryngeal Carcinoma

MedGen UID:
1710192
•Concept ID:
C5237269
•
Neoplastic Process

Definition

Laryngeal carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Laryngeal Carcinoma

Professional guidelines

PubMed

Survival prediction and treatment strategies for patients with advanced laryngeal carcinoma: a population-based study.
Zhu X, Heng Y, Zhou L, Zhang M, Li W, Tao L
Int J Clin Oncol 2020 Aug;25(8):1483-1491. Epub 2020 May 27 doi: 10.1007/s10147-020-01688-9. PMID: 32462387
Rehabilitation of the laryngectomised patient. Recommendations of the Spanish Society of Otolaryngology and Head and Neck Surgery.
Díaz de Cerio Canduela P, Arán González I, Barberá Durban R, Sistiaga Suárez A, Tobed Secall M, Parente Arias PL; en representación del Grupo de trabajo de Rehabilitación del Laringectomizado. Comisión de Cabeza y Cuello y Base de Cráneo
Acta Otorrinolaringol Esp (Engl Ed) 2019 May-Jun;70(3):169-174. Epub 2018 May 18 doi: 10.1016/j.otorri.2018.01.003. PMID: 29784244
Concurrent Radiotherapy and Triweekly Carboplatin for the Definitive Treatment of Locally Advanced Laryngeal Carcinoma.
Lu SM, Iganej S, Abdalla IA, Buchschacher GL
Am J Clin Oncol 2018 Jun;41(6):595-600. doi: 10.1097/COC.0000000000000330. PMID: 27635621

Recent clinical studies

Etiology

Decisional Conflict in Patients with Advanced Laryngeal Carcinoma: A Multicenter Study.
Heirman AN, de Kort DP, Petersen JF, Al-Mamgani A, Eerenstein SEJ, de Kleijn BJ, Hoebers F, Tijink BM, Stuiver MM, van der Molen L, Dirven R, Halmos GB, van den Brekel MWM
Laryngoscope 2024 Aug;134(8):3604-3610. Epub 2024 Feb 17 doi: 10.1002/lary.31336. PMID: 38366759
The importance of weight loss during definitive radiotherapy in patients with laryngeal carcinoma.
Yurut-Caloglu V, Caloglu M, Turkkan G
J Cancer Res Ther 2022 Apr-Jun;18(3):638-643. doi: 10.4103/jcrt.JCRT_727_20. PMID: 35900534
Survival prediction and treatment strategies for patients with advanced laryngeal carcinoma: a population-based study.
Zhu X, Heng Y, Zhou L, Zhang M, Li W, Tao L
Int J Clin Oncol 2020 Aug;25(8):1483-1491. Epub 2020 May 27 doi: 10.1007/s10147-020-01688-9. PMID: 32462387
Concurrent Radiotherapy and Triweekly Carboplatin for the Definitive Treatment of Locally Advanced Laryngeal Carcinoma.
Lu SM, Iganej S, Abdalla IA, Buchschacher GL
Am J Clin Oncol 2018 Jun;41(6):595-600. doi: 10.1097/COC.0000000000000330. PMID: 27635621
Carcinoma of the larynx treated with hypofractionated radiation and hyperbaric oxygen: long-term tumor control and complications.
Haffty BG, Hurley RA, Peters LG
Int J Radiat Oncol Biol Phys 1999 Aug 1;45(1):13-20. doi: 10.1016/s0360-3016(99)00126-1. PMID: 10477001

Diagnosis

The importance of weight loss during definitive radiotherapy in patients with laryngeal carcinoma.
Yurut-Caloglu V, Caloglu M, Turkkan G
J Cancer Res Ther 2022 Apr-Jun;18(3):638-643. doi: 10.4103/jcrt.JCRT_727_20. PMID: 35900534
Results of salvage surgery for local or regional recurrence after larynx preservation with induction chemotherapy and radiotherapy.
León X, Quer M, Orús C, López M, Gras JR, Vega M
Head Neck 2001 Sep;23(9):733-8. doi: 10.1002/hed.1104. PMID: 11505482

Therapy

The importance of weight loss during definitive radiotherapy in patients with laryngeal carcinoma.
Yurut-Caloglu V, Caloglu M, Turkkan G
J Cancer Res Ther 2022 Apr-Jun;18(3):638-643. doi: 10.4103/jcrt.JCRT_727_20. PMID: 35900534
Concurrent Radiotherapy and Triweekly Carboplatin for the Definitive Treatment of Locally Advanced Laryngeal Carcinoma.
Lu SM, Iganej S, Abdalla IA, Buchschacher GL
Am J Clin Oncol 2018 Jun;41(6):595-600. doi: 10.1097/COC.0000000000000330. PMID: 27635621
Results of an organ preservation protocol with induction chemotherapy and radiotherapy in patients with locally advanced laryngeal carcinoma.
León X, López-Pousa A, de Vega M, Orús C, de Juan M, Quer M
Eur Arch Otorhinolaryngol 2005 Feb;262(2):93-8. Epub 2004 Feb 18 doi: 10.1007/s00405-004-0749-5. PMID: 14986021
Hyperfractionated radiotherapy and concomitant cisplatin for locally advanced laryngeal and hypopharyngeal carcinomas: final results of a single institutional program.
de la Vega FA, García RV, Domínguez D, Iturre EV, López EM, Alonso SM, Romero P, Sola JM
Am J Clin Oncol 2003 Dec;26(6):550-7. doi: 10.1097/01.coc.0000037741.09729.F4. PMID: 14663370
Carcinoma of the larynx treated with hypofractionated radiation and hyperbaric oxygen: long-term tumor control and complications.
Haffty BG, Hurley RA, Peters LG
Int J Radiat Oncol Biol Phys 1999 Aug 1;45(1):13-20. doi: 10.1016/s0360-3016(99)00126-1. PMID: 10477001

Prognosis

The importance of weight loss during definitive radiotherapy in patients with laryngeal carcinoma.
Yurut-Caloglu V, Caloglu M, Turkkan G
J Cancer Res Ther 2022 Apr-Jun;18(3):638-643. doi: 10.4103/jcrt.JCRT_727_20. PMID: 35900534
Survival prediction and treatment strategies for patients with advanced laryngeal carcinoma: a population-based study.
Zhu X, Heng Y, Zhou L, Zhang M, Li W, Tao L
Int J Clin Oncol 2020 Aug;25(8):1483-1491. Epub 2020 May 27 doi: 10.1007/s10147-020-01688-9. PMID: 32462387
Concurrent Radiotherapy and Triweekly Carboplatin for the Definitive Treatment of Locally Advanced Laryngeal Carcinoma.
Lu SM, Iganej S, Abdalla IA, Buchschacher GL
Am J Clin Oncol 2018 Jun;41(6):595-600. doi: 10.1097/COC.0000000000000330. PMID: 27635621
Hyperfractionated radiotherapy and concomitant cisplatin for locally advanced laryngeal and hypopharyngeal carcinomas: final results of a single institutional program.
de la Vega FA, García RV, Domínguez D, Iturre EV, López EM, Alonso SM, Romero P, Sola JM
Am J Clin Oncol 2003 Dec;26(6):550-7. doi: 10.1097/01.coc.0000037741.09729.F4. PMID: 14663370
Carcinoma of the larynx treated with hypofractionated radiation and hyperbaric oxygen: long-term tumor control and complications.
Haffty BG, Hurley RA, Peters LG
Int J Radiat Oncol Biol Phys 1999 Aug 1;45(1):13-20. doi: 10.1016/s0360-3016(99)00126-1. PMID: 10477001

Clinical prediction guides

Decisional Conflict in Patients with Advanced Laryngeal Carcinoma: A Multicenter Study.
Heirman AN, de Kort DP, Petersen JF, Al-Mamgani A, Eerenstein SEJ, de Kleijn BJ, Hoebers F, Tijink BM, Stuiver MM, van der Molen L, Dirven R, Halmos GB, van den Brekel MWM
Laryngoscope 2024 Aug;134(8):3604-3610. Epub 2024 Feb 17 doi: 10.1002/lary.31336. PMID: 38366759
The importance of weight loss during definitive radiotherapy in patients with laryngeal carcinoma.
Yurut-Caloglu V, Caloglu M, Turkkan G
J Cancer Res Ther 2022 Apr-Jun;18(3):638-643. doi: 10.4103/jcrt.JCRT_727_20. PMID: 35900534
Survival prediction and treatment strategies for patients with advanced laryngeal carcinoma: a population-based study.
Zhu X, Heng Y, Zhou L, Zhang M, Li W, Tao L
Int J Clin Oncol 2020 Aug;25(8):1483-1491. Epub 2020 May 27 doi: 10.1007/s10147-020-01688-9. PMID: 32462387
Carcinoma of the larynx treated with hypofractionated radiation and hyperbaric oxygen: long-term tumor control and complications.
Haffty BG, Hurley RA, Peters LG
Int J Radiat Oncol Biol Phys 1999 Aug 1;45(1):13-20. doi: 10.1016/s0360-3016(99)00126-1. PMID: 10477001

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