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Locally Advanced High Grade Sarcoma

MedGen UID:
1708864
Concept ID:
C5239029
Neoplastic Process

Definition

High grade sarcoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced High Grade Sarcoma

Professional guidelines

PubMed

Alexiev BA, Vormittag-Nocito ER, Peabody TD, Samet J, Laskin WB
Hum Pathol 2023 Sep;139:126-134. Epub 2023 Jun 16 doi: 10.1016/j.humpath.2023.06.004. PMID: 37805864
D'Ambrosio L, Van Houdt W, Stelmes JJ, Gronchi A
Curr Opin Oncol 2022 Jul 1;34(4):328-334. doi: 10.1097/CCO.0000000000000851. PMID: 35837704
Novetsky AP, Powell MA
Curr Opin Oncol 2013 Sep;25(5):546-52. doi: 10.1097/CCO.0b013e328363e0ef. PMID: 23942299

Recent clinical studies

Etiology

Marth C, Tarnawski R, Tyulyandina A, Pignata S, Gilbert L, Kaen D, Rubio MJ, Frentzas S, Beiner M, Magallanes-Maciel M, Farrelly L, Choi CH, Berger R, Lee C, Vulsteke C, Hasegawa K, Braicu EI, Wu X, McKenzie J, Lee JJ, Makker V
Int J Gynecol Cancer 2022 Jan;32(1):93-100. Epub 2021 Nov 19 doi: 10.1136/ijgc-2021-003017. PMID: 34799418Free PMC Article
Köbel M, Kang EY
Int J Gynecol Pathol 2021 Jan;40(1):32-40. doi: 10.1097/PGP.0000000000000725. PMID: 33290354
Geoerger B, Kang HJ, Yalon-Oren M, Marshall LV, Vezina C, Pappo A, Laetsch TW, Petrilli AS, Ebinger M, Toporski J, Glade-Bender J, Nicholls W, Fox E, DuBois SG, Macy ME, Cohn SL, Pathiraja K, Diede SJ, Ebbinghaus S, Pinto N
Lancet Oncol 2020 Jan;21(1):121-133. Epub 2019 Dec 4 doi: 10.1016/S1470-2045(19)30671-0. PMID: 31812554
Judson I, Verweij J, Gelderblom H, Hartmann JT, Schöffski P, Blay JY, Kerst JM, Sufliarsky J, Whelan J, Hohenberger P, Krarup-Hansen A, Alcindor T, Marreaud S, Litière S, Hermans C, Fisher C, Hogendoorn PC, dei Tos AP, van der Graaf WT; European Organisation and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
Lancet Oncol 2014 Apr;15(4):415-23. Epub 2014 Mar 5 doi: 10.1016/S1470-2045(14)70063-4. PMID: 24618336
Novetsky AP, Powell MA
Curr Opin Oncol 2013 Sep;25(5):546-52. doi: 10.1097/CCO.0b013e328363e0ef. PMID: 23942299

Diagnosis

Marinoff AE, Spurr LF, Fong C, Li YY, Forrest SJ, Ward A, Doan D, Corson L, Mauguen A, Pinto N, Maese L, Colace S, Macy ME, Kim A, Sabnis AJ, Applebaum MA, Laetsch TW, Glade-Bender J, Weiser DA, Anderson M, Crompton BD, Meyers P, Zehir A, MacConaill L, Lindeman N, Nowak JA, Ladanyi M, Church AJ, Cherniack AD, Shukla N, Janeway KA
JCO Precis Oncol 2023 Mar;7:e2200334. doi: 10.1200/PO.22.00334. PMID: 36996377Free PMC Article
Bogani G, Ray-Coquard I, Concin N, Ngoi NYL, Morice P, Caruso G, Enomoto T, Takehara K, Denys H, Lorusso D, Coleman R, Vaughan MM, Takano M, Provencher DM, Sagae S, Wimberger P, Póka R, Segev Y, Kim SI, Kim JW, Candido Dos Reis FJ, Ramirez PT, Mariani A, Leitao M, Makker V, Abu-Rustum NR, Vergote I, Zannoni G, Tan D, McCormack M, Paolini B, Bini M, Raspagliesi F, Benedetti Panici P, Di Donato V, Muzii L, Colombo N, Pignata S, Scambia G, Monk BJ
Int J Gynecol Cancer 2023 Feb 6;33(2):147-174. doi: 10.1136/ijgc-2022-004073. PMID: 36585027
Marth C, Tarnawski R, Tyulyandina A, Pignata S, Gilbert L, Kaen D, Rubio MJ, Frentzas S, Beiner M, Magallanes-Maciel M, Farrelly L, Choi CH, Berger R, Lee C, Vulsteke C, Hasegawa K, Braicu EI, Wu X, McKenzie J, Lee JJ, Makker V
Int J Gynecol Cancer 2022 Jan;32(1):93-100. Epub 2021 Nov 19 doi: 10.1136/ijgc-2021-003017. PMID: 34799418Free PMC Article
Köbel M, Kang EY
Int J Gynecol Pathol 2021 Jan;40(1):32-40. doi: 10.1097/PGP.0000000000000725. PMID: 33290354
Novetsky AP, Powell MA
Curr Opin Oncol 2013 Sep;25(5):546-52. doi: 10.1097/CCO.0b013e328363e0ef. PMID: 23942299

Therapy

Bogani G, Ray-Coquard I, Concin N, Ngoi NYL, Morice P, Caruso G, Enomoto T, Takehara K, Denys H, Lorusso D, Coleman R, Vaughan MM, Takano M, Provencher DM, Sagae S, Wimberger P, Póka R, Segev Y, Kim SI, Kim JW, Candido Dos Reis FJ, Ramirez PT, Mariani A, Leitao M, Makker V, Abu-Rustum NR, Vergote I, Zannoni G, Tan D, McCormack M, Paolini B, Bini M, Raspagliesi F, Benedetti Panici P, Di Donato V, Muzii L, Colombo N, Pignata S, Scambia G, Monk BJ
Int J Gynecol Cancer 2023 Feb 6;33(2):147-174. doi: 10.1136/ijgc-2022-004073. PMID: 36585027
Marth C, Tarnawski R, Tyulyandina A, Pignata S, Gilbert L, Kaen D, Rubio MJ, Frentzas S, Beiner M, Magallanes-Maciel M, Farrelly L, Choi CH, Berger R, Lee C, Vulsteke C, Hasegawa K, Braicu EI, Wu X, McKenzie J, Lee JJ, Makker V
Int J Gynecol Cancer 2022 Jan;32(1):93-100. Epub 2021 Nov 19 doi: 10.1136/ijgc-2021-003017. PMID: 34799418Free PMC Article
Geoerger B, Kang HJ, Yalon-Oren M, Marshall LV, Vezina C, Pappo A, Laetsch TW, Petrilli AS, Ebinger M, Toporski J, Glade-Bender J, Nicholls W, Fox E, DuBois SG, Macy ME, Cohn SL, Pathiraja K, Diede SJ, Ebbinghaus S, Pinto N
Lancet Oncol 2020 Jan;21(1):121-133. Epub 2019 Dec 4 doi: 10.1016/S1470-2045(19)30671-0. PMID: 31812554
Judson I, Verweij J, Gelderblom H, Hartmann JT, Schöffski P, Blay JY, Kerst JM, Sufliarsky J, Whelan J, Hohenberger P, Krarup-Hansen A, Alcindor T, Marreaud S, Litière S, Hermans C, Fisher C, Hogendoorn PC, dei Tos AP, van der Graaf WT; European Organisation and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
Lancet Oncol 2014 Apr;15(4):415-23. Epub 2014 Mar 5 doi: 10.1016/S1470-2045(14)70063-4. PMID: 24618336
Novetsky AP, Powell MA
Curr Opin Oncol 2013 Sep;25(5):546-52. doi: 10.1097/CCO.0b013e328363e0ef. PMID: 23942299

Prognosis

Köbel M, Kang EY
Int J Gynecol Pathol 2021 Jan;40(1):32-40. doi: 10.1097/PGP.0000000000000725. PMID: 33290354
Geoerger B, Kang HJ, Yalon-Oren M, Marshall LV, Vezina C, Pappo A, Laetsch TW, Petrilli AS, Ebinger M, Toporski J, Glade-Bender J, Nicholls W, Fox E, DuBois SG, Macy ME, Cohn SL, Pathiraja K, Diede SJ, Ebbinghaus S, Pinto N
Lancet Oncol 2020 Jan;21(1):121-133. Epub 2019 Dec 4 doi: 10.1016/S1470-2045(19)30671-0. PMID: 31812554
Thiel FC, Halmen S
Oncol Res Treat 2018;41(11):687-692. Epub 2018 Oct 13 doi: 10.1159/000494225. PMID: 30317238
Anderson ME
Orthop Clin North Am 2016 Jan;47(1):283-92. doi: 10.1016/j.ocl.2015.08.022. PMID: 26614941
Novetsky AP, Powell MA
Curr Opin Oncol 2013 Sep;25(5):546-52. doi: 10.1097/CCO.0b013e328363e0ef. PMID: 23942299

Clinical prediction guides

van Weelden WJ, Birkendahl PB, Lalisang RI, IntHout J, Kruitwagen RFPM, Romano A, Pijnenborg JMA
BJOG 2023 Jan;130(2):143-152. Epub 2022 Nov 13 doi: 10.1111/1471-0528.17331. PMID: 36264251Free PMC Article
Köbel M, Kang EY
Int J Gynecol Pathol 2021 Jan;40(1):32-40. doi: 10.1097/PGP.0000000000000725. PMID: 33290354
Geoerger B, Kang HJ, Yalon-Oren M, Marshall LV, Vezina C, Pappo A, Laetsch TW, Petrilli AS, Ebinger M, Toporski J, Glade-Bender J, Nicholls W, Fox E, DuBois SG, Macy ME, Cohn SL, Pathiraja K, Diede SJ, Ebbinghaus S, Pinto N
Lancet Oncol 2020 Jan;21(1):121-133. Epub 2019 Dec 4 doi: 10.1016/S1470-2045(19)30671-0. PMID: 31812554
Novetsky AP, Powell MA
Curr Opin Oncol 2013 Sep;25(5):546-52. doi: 10.1097/CCO.0b013e328363e0ef. PMID: 23942299
Potter BO, Sturgis EM
Surg Oncol Clin N Am 2003 Apr;12(2):379-417. doi: 10.1016/s1055-3207(03)00005-x. PMID: 12916461

Recent systematic reviews

van Weelden WJ, Birkendahl PB, Lalisang RI, IntHout J, Kruitwagen RFPM, Romano A, Pijnenborg JMA
BJOG 2023 Jan;130(2):143-152. Epub 2022 Nov 13 doi: 10.1111/1471-0528.17331. PMID: 36264251Free PMC Article
Peinemann F, Enk H, Smith LA
Cochrane Database Syst Rev 2017 Apr 13;4(4):CD008216. doi: 10.1002/14651858.CD008216.pub5. PMID: 28407197Free PMC Article
Peinemann F, Smith LA, Kromp M, Bartel C, Kröger N, Kulig M
Cochrane Database Syst Rev 2011 Feb 16;(2):CD008216. doi: 10.1002/14651858.CD008216.pub3. PMID: 21328307
Verma S, Younus J, Stys-Norman D, Haynes AE, Blackstein M; Sarcoma Disease Site Group of Cancer Care Ontario's Program in Evidence-based Care
Cancer 2008 Mar 15;112(6):1197-205. doi: 10.1002/cncr.23302. PMID: 18224666
Bastiaannet E, Groen H, Jager PL, Cobben DC, van der Graaf WT, Vaalburg W, Hoekstra HJ
Cancer Treat Rev 2004 Feb;30(1):83-101. doi: 10.1016/j.ctrv.2003.07.004. PMID: 14766127

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