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Secondary vesicoureteral reflux

MedGen UID:
1707220
•Concept ID:
C5232302
•
Disease or Syndrome
Synonyms: Reflux, Secondary Vesicoureteral; Secondary Vesicoureteral Reflux; Vesicoureteral Reflux, Secondary
 
HPO: HP:0033739

Definition

Vesicoureteral reflux induced by increased bladder pressures in patients with voiding dysfunction e.g. in case of congenital posterior urethral valves or neurogenic bladder dysfunction. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSecondary vesicoureteral reflux

Professional guidelines

PubMed

Systematic review and meta-analysis to study the outcomes of proactive versus delayed management in children with a congenital neurogenic bladder.
Li Y, Stern N, Wang PZ, Braga LH, Dave S
J Pediatr Urol 2023 Dec;19(6):730-741. Epub 2023 Sep 7 doi: 10.1016/j.jpurol.2023.08.033. PMID: 37726188
Guidelines for the medical management of pediatric vesicoureteral reflux.
Miyakita H, Hayashi Y, Mitsui T, Okawada M, Kinoshita Y, Kimata T, Koikawa Y, Sakai K, Satoh H, Tokunaga M, Naitoh Y, Niimura F, Matsuoka H, Mizuno K, Kaneko K, Kubota M
Int J Urol 2020 Jun;27(6):480-490. Epub 2020 Apr 1 doi: 10.1111/iju.14223. PMID: 32239562Free PMC Article
Management of vesicoureteral reflux secondary to neurogenic bladder.
Morioka A, Miyano T, Ando K, Yamataka T, Lane GJ
Pediatr Surg Int 1998 Oct;13(8):584-6. doi: 10.1007/s003830050409. PMID: 9799381

Recent clinical studies

Etiology

Systematic review and meta-analysis to study the outcomes of proactive versus delayed management in children with a congenital neurogenic bladder.
Li Y, Stern N, Wang PZ, Braga LH, Dave S
J Pediatr Urol 2023 Dec;19(6):730-741. Epub 2023 Sep 7 doi: 10.1016/j.jpurol.2023.08.033. PMID: 37726188
Robotic ureteral reimplantation and uretero-ureterostomy treating the ureterovesical junction pathologies in children: technical considerations and preliminary results.
Mattioli G, Lena F, Fiorenza V, Carlucci M
J Robot Surg 2023 Apr;17(2):659-667. Epub 2022 Oct 26 doi: 10.1007/s11701-022-01478-7. PMID: 36287349
Microbladder due to Granulomatous Cystitis Secondary to BCG Treatment.
Medina-González M, Panach-Navarrete J, Mata-Cano D, Martínez Jabaloyas JM
Arch Esp Urol 2022 Oct;75(8):729-730. doi: 10.56434/j.arch.esp.urol.20227508.105. PMID: 36330575
Guidelines for the medical management of pediatric vesicoureteral reflux.
Miyakita H, Hayashi Y, Mitsui T, Okawada M, Kinoshita Y, Kimata T, Koikawa Y, Sakai K, Satoh H, Tokunaga M, Naitoh Y, Niimura F, Matsuoka H, Mizuno K, Kaneko K, Kubota M
Int J Urol 2020 Jun;27(6):480-490. Epub 2020 Apr 1 doi: 10.1111/iju.14223. PMID: 32239562Free PMC Article
CKD and bladder problems in children.
Penna FJ, Elder JS
Adv Chronic Kidney Dis 2011 Sep;18(5):362-9. doi: 10.1053/j.ackd.2011.08.001. PMID: 21896378

Diagnosis

Systematic review and meta-analysis to study the outcomes of proactive versus delayed management in children with a congenital neurogenic bladder.
Li Y, Stern N, Wang PZ, Braga LH, Dave S
J Pediatr Urol 2023 Dec;19(6):730-741. Epub 2023 Sep 7 doi: 10.1016/j.jpurol.2023.08.033. PMID: 37726188
Microbladder due to Granulomatous Cystitis Secondary to BCG Treatment.
Medina-González M, Panach-Navarrete J, Mata-Cano D, Martínez Jabaloyas JM
Arch Esp Urol 2022 Oct;75(8):729-730. doi: 10.56434/j.arch.esp.urol.20227508.105. PMID: 36330575
Guidelines for the medical management of pediatric vesicoureteral reflux.
Miyakita H, Hayashi Y, Mitsui T, Okawada M, Kinoshita Y, Kimata T, Koikawa Y, Sakai K, Satoh H, Tokunaga M, Naitoh Y, Niimura F, Matsuoka H, Mizuno K, Kaneko K, Kubota M
Int J Urol 2020 Jun;27(6):480-490. Epub 2020 Apr 1 doi: 10.1111/iju.14223. PMID: 32239562Free PMC Article
Recent trends of genitourinary endoscopy in children.
Nonomura K, Kakizaki H
Int J Urol 2005 Jul;12(7):607-14. doi: 10.1111/j.1442-2042.2005.01115.x. PMID: 16045552
Ultrasonic measurement of bladder weight as a novel urodynamic modality.
Ukimura O, Kojima M, Iwata T, Inaba M, Miki T
Adv Exp Med Biol 2003;539(Pt A):311-5. doi: 10.1007/978-1-4419-8889-8_23. PMID: 15088914

Therapy

Systematic review and meta-analysis to study the outcomes of proactive versus delayed management in children with a congenital neurogenic bladder.
Li Y, Stern N, Wang PZ, Braga LH, Dave S
J Pediatr Urol 2023 Dec;19(6):730-741. Epub 2023 Sep 7 doi: 10.1016/j.jpurol.2023.08.033. PMID: 37726188
Microbladder due to Granulomatous Cystitis Secondary to BCG Treatment.
Medina-González M, Panach-Navarrete J, Mata-Cano D, Martínez Jabaloyas JM
Arch Esp Urol 2022 Oct;75(8):729-730. doi: 10.56434/j.arch.esp.urol.20227508.105. PMID: 36330575
Long-term followup after endoscopic treatment of vesicoureteral reflux with dextranomer/hyaluronic acid copolymer in patients with neurogenic bladder.
Polackwich AS, Skoog SJ, Austin JC
J Urol 2012 Oct;188(4 Suppl):1511-5. Epub 2012 Aug 19 doi: 10.1016/j.juro.2012.03.046. PMID: 22910250
Transurethral injection therapy with dextranomer/hyaluronic acid copolymer (Deflux) for treatment of secondary vesicoureteral reflux after renal transplantation.
Seifert HH, Mazzola B, Ruszat R, Muller A, Steiger J, Bachmann A, Sulser T
J Endourol 2007 Nov;21(11):1357-60. doi: 10.1089/end.2007.0020. PMID: 18042030
The Mitrofanoff procedure: 20 years later.
Liard A, Séguier-Lipszyc E, Mathiot A, Mitrofanoff P
J Urol 2001 Jun;165(6 Pt 2):2394-8. doi: 10.1016/S0022-5347(05)66213-1. PMID: 11371985

Prognosis

Guidelines for the medical management of pediatric vesicoureteral reflux.
Miyakita H, Hayashi Y, Mitsui T, Okawada M, Kinoshita Y, Kimata T, Koikawa Y, Sakai K, Satoh H, Tokunaga M, Naitoh Y, Niimura F, Matsuoka H, Mizuno K, Kaneko K, Kubota M
Int J Urol 2020 Jun;27(6):480-490. Epub 2020 Apr 1 doi: 10.1111/iju.14223. PMID: 32239562Free PMC Article
Early discontinuation of antibiotic prophylaxis in patients with persistent primary vesicoureteral reflux initially detected during infancy: outcome analysis and risk factors for febrile urinary tract infection.
Moriya K, Mitsui T, Kitta T, Nakamura M, Kanno Y, Kon M, Nishimura Y, Shinohara N, Nonomura K
J Urol 2015 Feb;193(2):637-42. Epub 2014 Aug 9 doi: 10.1016/j.juro.2014.08.007. PMID: 25111912
Long-term followup after endoscopic treatment of vesicoureteral reflux with dextranomer/hyaluronic acid copolymer in patients with neurogenic bladder.
Polackwich AS, Skoog SJ, Austin JC
J Urol 2012 Oct;188(4 Suppl):1511-5. Epub 2012 Aug 19 doi: 10.1016/j.juro.2012.03.046. PMID: 22910250
Predictive factors for contralateral reflux in patients with conservatively treated unilateral vesicoureteral reflux.
Barroso U Jr, Barroso VA, de Bessa J Jr, Calado AA, Zerati Filho M
J Urol 2008 Jul;180(1):297-9; discussion 299. Epub 2008 May 21 doi: 10.1016/j.juro.2008.03.066. PMID: 18499171
Ultrasonic measurement of bladder weight as a novel urodynamic modality.
Ukimura O, Kojima M, Iwata T, Inaba M, Miki T
Adv Exp Med Biol 2003;539(Pt A):311-5. doi: 10.1007/978-1-4419-8889-8_23. PMID: 15088914

Clinical prediction guides

Systematic review and meta-analysis to study the outcomes of proactive versus delayed management in children with a congenital neurogenic bladder.
Li Y, Stern N, Wang PZ, Braga LH, Dave S
J Pediatr Urol 2023 Dec;19(6):730-741. Epub 2023 Sep 7 doi: 10.1016/j.jpurol.2023.08.033. PMID: 37726188
Guidelines for the medical management of pediatric vesicoureteral reflux.
Miyakita H, Hayashi Y, Mitsui T, Okawada M, Kinoshita Y, Kimata T, Koikawa Y, Sakai K, Satoh H, Tokunaga M, Naitoh Y, Niimura F, Matsuoka H, Mizuno K, Kaneko K, Kubota M
Int J Urol 2020 Jun;27(6):480-490. Epub 2020 Apr 1 doi: 10.1111/iju.14223. PMID: 32239562Free PMC Article
Predictive factors for contralateral reflux in patients with conservatively treated unilateral vesicoureteral reflux.
Barroso U Jr, Barroso VA, de Bessa J Jr, Calado AA, Zerati Filho M
J Urol 2008 Jul;180(1):297-9; discussion 299. Epub 2008 May 21 doi: 10.1016/j.juro.2008.03.066. PMID: 18499171
Ultrasonic measurement of bladder weight as a novel urodynamic modality.
Ukimura O, Kojima M, Iwata T, Inaba M, Miki T
Adv Exp Med Biol 2003;539(Pt A):311-5. doi: 10.1007/978-1-4419-8889-8_23. PMID: 15088914
Renal growth and progression of reflux nephropathy in children with vesicoureteral reflux.
Shimada K, Matsui T, Ogino T, Arima M, Mori Y, Ikoma F
J Urol 1988 Nov;140(5 Pt 2):1097-100. doi: 10.1016/s0022-5347(17)41970-7. PMID: 3184282

Recent systematic reviews

Systematic review and meta-analysis to study the outcomes of proactive versus delayed management in children with a congenital neurogenic bladder.
Li Y, Stern N, Wang PZ, Braga LH, Dave S
J Pediatr Urol 2023 Dec;19(6):730-741. Epub 2023 Sep 7 doi: 10.1016/j.jpurol.2023.08.033. PMID: 37726188

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