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Sinonasal Adenocarcinoma, Non-Intestinal-Type

MedGen UID:
1700800
•Concept ID:
C5205696
•
Neoplastic Process
Synonym: Nasal Cavity and Paranasal Sinus Adenocarcinoma, Non-Intestinal-Type

Definition

An adenocarcinoma that arises from the sinonasal tract. It is characterized by the absence of features that resemble intestinal adenocarcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSinonasal Adenocarcinoma, Non-Intestinal-Type

Professional guidelines

PubMed

Challenging differential diagnoses in small biopsies from the sinonasal tract.
Israel AK, Cracolici V, Griffith CC
Semin Diagn Pathol 2023 Sep;40(5):321-332. Epub 2023 Apr 14 doi: 10.1053/j.semdp.2023.04.011. PMID: 37085435

Recent clinical studies

Etiology

Challenging differential diagnoses in small biopsies from the sinonasal tract.
Israel AK, Cracolici V, Griffith CC
Semin Diagn Pathol 2023 Sep;40(5):321-332. Epub 2023 Apr 14 doi: 10.1053/j.semdp.2023.04.011. PMID: 37085435
Sinonasal intestinal- and non-intestinal-type adenocarcinoma in China: a retrospective study of 14 cases.
Li G, Shi Y, Liu Q, Zhang H, Xue K, Song X, Gu Y, Sun X, Dai Q, Yu H
Acta Otolaryngol 2023 Feb;143(2):185-190. Epub 2023 Feb 13 doi: 10.1080/00016489.2023.2175032. PMID: 36780311
Low-grade non-intestinal-type sinonasal adenocarcinoma: a histologically distinctive but molecularly heterogeneous entity.
Rooper LM, Thompson LDR, Gagan J, Hwang JSG, London NR, Mikula MW, Stevens TM, Bishop JA
Mod Pathol 2022 Sep;35(9):1160-1167. Epub 2022 Mar 23 doi: 10.1038/s41379-022-01068-w. PMID: 35322195
Sinonasal low-grade non-intestinal-type adenocarcinoma: A retrospective analysis and literature review.
Yue C, Piao Y, Bai Y, Liu H, Zhang L
Ann Diagn Pathol 2021 Jun;52:151709. Epub 2021 Jan 29 doi: 10.1016/j.anndiagpath.2021.151709. PMID: 33550111
Sinonasal Non-Intestinal-Type Adenocarcinoma: A Retrospective Review of 22 Patients.
Bignami M, Lepera D, Volpi L, Lambertoni A, Arosio A, Pistochini A, Nicolai P, Castelnuovo P
World Neurosurg 2018 Dec;120:e962-e969. Epub 2018 Sep 6 doi: 10.1016/j.wneu.2018.08.201. PMID: 30196179

Diagnosis

Sinonasal intestinal- and non-intestinal-type adenocarcinoma in China: a retrospective study of 14 cases.
Li G, Shi Y, Liu Q, Zhang H, Xue K, Song X, Gu Y, Sun X, Dai Q, Yu H
Acta Otolaryngol 2023 Feb;143(2):185-190. Epub 2023 Feb 13 doi: 10.1080/00016489.2023.2175032. PMID: 36780311
Low-grade non-intestinal-type sinonasal adenocarcinoma: a histologically distinctive but molecularly heterogeneous entity.
Rooper LM, Thompson LDR, Gagan J, Hwang JSG, London NR, Mikula MW, Stevens TM, Bishop JA
Mod Pathol 2022 Sep;35(9):1160-1167. Epub 2022 Mar 23 doi: 10.1038/s41379-022-01068-w. PMID: 35322195
Sinonasal low-grade non-intestinal-type adenocarcinoma: A retrospective analysis and literature review.
Yue C, Piao Y, Bai Y, Liu H, Zhang L
Ann Diagn Pathol 2021 Jun;52:151709. Epub 2021 Jan 29 doi: 10.1016/j.anndiagpath.2021.151709. PMID: 33550111
A Comprehensive Update on Intestinal- and Non-Intestinal-Type Adenocarcinomas.
Vander Poorten V, Jorissen M
Adv Otorhinolaryngol 2020;84:137-153. Epub 2020 Jul 30 doi: 10.1159/000457934. PMID: 32731230
Glandular Neoplasia of the Sinonasal Tract.
Stelow EB
Surg Pathol Clin 2017 Mar;10(1):89-102. doi: 10.1016/j.path.2016.10.004. PMID: 28153137

Therapy

A case of high-grade non-intestinal paranasal sinus adenocarcinoma primary in the maxillary sinus: targeted therapy after postoperative immunocombination with chemotherapy.
Yang L, Lu L, Ma J, Xu Z, Li N
J Cancer Res Clin Oncol 2024 Aug 3;150(8):381. doi: 10.1007/s00432-024-05744-z. PMID: 39097562Free PMC Article
The Role of SATB2 as a Diagnostic Marker of Sinonasal Intestinal-type Adenocarcinoma.
Skalova A, Sar A, Laco J, Metelkova A, Miesbauerova M, Steiner P, Švajdler M, Michal M
Appl Immunohistochem Mol Morphol 2018 Feb;26(2):140-146. doi: 10.1097/PAI.0000000000000388. PMID: 27258560

Prognosis

A Comprehensive Update on Intestinal- and Non-Intestinal-Type Adenocarcinomas.
Vander Poorten V, Jorissen M
Adv Otorhinolaryngol 2020;84:137-153. Epub 2020 Jul 30 doi: 10.1159/000457934. PMID: 32731230
IDH2 Mutation Analysis in Undifferentiated and Poorly Differentiated Sinonasal Carcinomas for Diagnosis and Clinical Management.
Riobello C, López-Hernández A, Cabal VN, García-Marín R, Suárez-Fernández L, Sánchez-Fernández P, Vivanco B, Blanco V, López F, Franchi A, Llorente JL, Hermsen MA
Am J Surg Pathol 2020 Mar;44(3):396-405. doi: 10.1097/PAS.0000000000001420. PMID: 31876581
Immunohistochemical profiling of mucins in sinonasal adenocarcinomas.
Taverna C, Maggiore G, Cannavicci A, Bonomo P, Santucci M, Franchi A
Pathol Res Pract 2019 Jul;215(7):152439. Epub 2019 May 4 doi: 10.1016/j.prp.2019.152439. PMID: 31076280
Sinonasal Non-Intestinal-Type Adenocarcinoma: A Retrospective Review of 22 Patients.
Bignami M, Lepera D, Volpi L, Lambertoni A, Arosio A, Pistochini A, Nicolai P, Castelnuovo P
World Neurosurg 2018 Dec;120:e962-e969. Epub 2018 Sep 6 doi: 10.1016/j.wneu.2018.08.201. PMID: 30196179
The Role of SATB2 as a Diagnostic Marker of Sinonasal Intestinal-type Adenocarcinoma.
Skalova A, Sar A, Laco J, Metelkova A, Miesbauerova M, Steiner P, Švajdler M, Michal M
Appl Immunohistochem Mol Morphol 2018 Feb;26(2):140-146. doi: 10.1097/PAI.0000000000000388. PMID: 27258560

Clinical prediction guides

A case of high-grade non-intestinal paranasal sinus adenocarcinoma primary in the maxillary sinus: targeted therapy after postoperative immunocombination with chemotherapy.
Yang L, Lu L, Ma J, Xu Z, Li N
J Cancer Res Clin Oncol 2024 Aug 3;150(8):381. doi: 10.1007/s00432-024-05744-z. PMID: 39097562Free PMC Article
Analysis of clinicopathologic features and expression of NR4A3 in sinonasal acinic cell carcinoma.
Wang H, Zhai C, Zhang C, Liu Q, Zhang H, Sun X, Lin L, Yu H, Wang D
Mod Pathol 2022 May;35(5):594-600. Epub 2021 Dec 6 doi: 10.1038/s41379-021-00959-8. PMID: 34873305
Among sinonasal tumors, CDX-2 immunoexpression is not restricted to intestinal-type adenocarcinomas.
Tilson MP, Gallia GL, Bishop JA
Head Neck Pathol 2014 Mar;8(1):59-65. Epub 2013 Jul 12 doi: 10.1007/s12105-013-0475-7. PMID: 23846317Free PMC Article
An unusual case of low-grade tubulopapillary adenocarcinoma of the sinonasal tract.
Bansal A, Pradeep KE, Gumparthy KP
World J Surg Oncol 2008 May 20;6:54. doi: 10.1186/1477-7819-6-54. PMID: 18492272Free PMC Article

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