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Carcinoma Unspecified Site

MedGen UID:
1686331
•Concept ID:
C0848450
•
Neoplastic Process

Definition

Carcinoma in which the site of involvement is not specified. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCarcinoma Unspecified Site

Professional guidelines

PubMed

Management and outcome of recurrent well-differentiated thyroid carcinoma.
Palme CE, Waseem Z, Raza SN, Eski S, Walfish P, Freeman JL
Arch Otolaryngol Head Neck Surg 2004 Jul;130(7):819-24. doi: 10.1001/archotol.130.7.819. PMID: 15262757

Recent clinical studies

Etiology

Atypia Involving Fibroadenomas: Outcomes and Upgrade Rates.
Aripoli A, Winblad O, Balanoff C, Peterson J, Smith C, Huppe A, Hill M, Wermuth D, Gloyeske N
J Breast Imaging 2024 May 27;6(3):254-260. doi: 10.1093/jbi/wbae013. PMID: 38554256
Skin tumour specimen shrinkage with excision and formalin fixation-how much and why: a prospective study and discussion of the literature.
de Waal J
ANZ J Surg 2021 Dec;91(12):2744-2749. Epub 2021 Aug 30 doi: 10.1111/ans.17109. PMID: 34459559
Oro-facial malignancy in north of Iraq: a retrospective study of biopsied cases.
Fuoad SAA, Mohammad DN, Hamied MA, Garib BT
BMC Oral Health 2021 Mar 23;21(1):147. doi: 10.1186/s12903-021-01521-3. PMID: 33752665Free PMC Article
Evaluation of Potential Risk Factors that contribute to Malignant Transformation of Oral Lichen Planus: A Literature Review.
Agha-Hosseini F, Sheykhbahaei N, SadrZadeh-Afshar MS
J Contemp Dent Pract 2016 Aug 1;17(8):692-701. doi: 10.5005/jp-journals-10024-1914. PMID: 27659090
Differences in colorectal cancer survival between European and US populations: the importance of sub-site and morphology.
Gatta G, Ciccolallo L, Capocaccia R, Coleman MP, Hakulinen T, Møller H, Berrino F; EUROCARE Working Group
Eur J Cancer 2003 Oct;39(15):2214-22. doi: 10.1016/s0959-8049(03)00549-5. PMID: 14522381

Diagnosis

Atypia Involving Fibroadenomas: Outcomes and Upgrade Rates.
Aripoli A, Winblad O, Balanoff C, Peterson J, Smith C, Huppe A, Hill M, Wermuth D, Gloyeske N
J Breast Imaging 2024 May 27;6(3):254-260. doi: 10.1093/jbi/wbae013. PMID: 38554256
Epidemiologic patterns of biliary tract cancer in the United States: 2001-2015.
Koshiol J, Yu B, Kabadi SM, Baria K, Shroff RT
BMC Cancer 2022 Nov 16;22(1):1178. doi: 10.1186/s12885-022-10286-z. PMID: 36384474Free PMC Article
Frequency of synchronous malignant liver lesions initially detected by ultrasound in patients with newly diagnosed underlying non-hematologic malignant disease: a retrospective study in 434 patients.
Safai Zadeh E, Baumgarten MA, Dietrich CF, Görg C, Neesse A, Trenker C, Alhyari A
Z Gastroenterol 2022 Apr;60(4):586-592. Epub 2021 Oct 20 doi: 10.1055/a-1649-8857. PMID: 34670295
Oro-facial malignancy in north of Iraq: a retrospective study of biopsied cases.
Fuoad SAA, Mohammad DN, Hamied MA, Garib BT
BMC Oral Health 2021 Mar 23;21(1):147. doi: 10.1186/s12903-021-01521-3. PMID: 33752665Free PMC Article
Evaluation of Potential Risk Factors that contribute to Malignant Transformation of Oral Lichen Planus: A Literature Review.
Agha-Hosseini F, Sheykhbahaei N, SadrZadeh-Afshar MS
J Contemp Dent Pract 2016 Aug 1;17(8):692-701. doi: 10.5005/jp-journals-10024-1914. PMID: 27659090

Therapy

Efficacy of the MAGE-A3 cancer immunotherapeutic as adjuvant therapy in patients with resected MAGE-A3-positive non-small-cell lung cancer (MAGRIT): a randomised, double-blind, placebo-controlled, phase 3 trial.
Vansteenkiste JF, Cho BC, Vanakesa T, De Pas T, Zielinski M, Kim MS, Jassem J, Yoshimura M, Dahabreh J, Nakayama H, Havel L, Kondo H, Mitsudomi T, Zarogoulidis K, Gladkov OA, Udud K, Tada H, Hoffman H, Bugge A, Taylor P, Gonzalez EE, Liao ML, He J, Pujol JL, Louahed J, Debois M, Brichard V, Debruyne C, Therasse P, Altorki N
Lancet Oncol 2016 Jun;17(6):822-835. Epub 2016 Apr 27 doi: 10.1016/S1470-2045(16)00099-1. PMID: 27132212
Prognostic implications of site of recurrence in patients with recurrent well-differentiated thyroid cancer.
Waseem Z, Palme CE, Walfish P, Freeman JL
J Otolaryngol 2004 Dec;33(6):339-44. doi: 10.2310/7070.2004.04013. PMID: 15971647
Management and outcome of recurrent well-differentiated thyroid carcinoma.
Palme CE, Waseem Z, Raza SN, Eski S, Walfish P, Freeman JL
Arch Otolaryngol Head Neck Surg 2004 Jul;130(7):819-24. doi: 10.1001/archotol.130.7.819. PMID: 15262757
No evidence of association between methyldopa and biliary carcinoma.
Strom BL, Hibberd PL, Stolley PD
Int J Epidemiol 1985 Mar;14(1):86-90. doi: 10.1093/ije/14.1.86. PMID: 3988445
Observations of the site-specific carcinogenicity of vinyl chloride to humans.
Infante PF
Environ Health Perspect 1981 Oct;41:89-94. doi: 10.1289/ehp.814189. PMID: 7199431Free PMC Article

Prognosis

Epidemiologic patterns of biliary tract cancer in the United States: 2001-2015.
Koshiol J, Yu B, Kabadi SM, Baria K, Shroff RT
BMC Cancer 2022 Nov 16;22(1):1178. doi: 10.1186/s12885-022-10286-z. PMID: 36384474Free PMC Article
Skin tumour specimen shrinkage with excision and formalin fixation-how much and why: a prospective study and discussion of the literature.
de Waal J
ANZ J Surg 2021 Dec;91(12):2744-2749. Epub 2021 Aug 30 doi: 10.1111/ans.17109. PMID: 34459559
PD-L1 and PD-L2 Expression Levels Are Low in Primary and Secondary Adenoid Cystic Carcinomas of the Orbit: Therapeutic Implications.
Wolkow N, Jakobiec FA, Afrogheh AH, Kidd M, Eagle RC, Pai SI, Faquin WC
Ophthalmic Plast Reconstr Surg 2020 Sep/Oct;36(5):444-450. doi: 10.1097/IOP.0000000000001585. PMID: 31990894Free PMC Article
Unknown primary carcinoma in the Netherlands: decrease in incidence and survival times remain poor between 2000 and 2012.
Schroten-Loef C, Verhoeven RHA, de Hingh IHJT, van de Wouw AJ, van Laarhoven HWM, Lemmens VEPP
Eur J Cancer 2018 Sep;101:77-86. Epub 2018 Jul 20 doi: 10.1016/j.ejca.2018.06.032. PMID: 30031970
Differences in colorectal cancer survival between European and US populations: the importance of sub-site and morphology.
Gatta G, Ciccolallo L, Capocaccia R, Coleman MP, Hakulinen T, Møller H, Berrino F; EUROCARE Working Group
Eur J Cancer 2003 Oct;39(15):2214-22. doi: 10.1016/s0959-8049(03)00549-5. PMID: 14522381

Clinical prediction guides

Epidemiologic patterns of biliary tract cancer in the United States: 2001-2015.
Koshiol J, Yu B, Kabadi SM, Baria K, Shroff RT
BMC Cancer 2022 Nov 16;22(1):1178. doi: 10.1186/s12885-022-10286-z. PMID: 36384474Free PMC Article
Skin tumour specimen shrinkage with excision and formalin fixation-how much and why: a prospective study and discussion of the literature.
de Waal J
ANZ J Surg 2021 Dec;91(12):2744-2749. Epub 2021 Aug 30 doi: 10.1111/ans.17109. PMID: 34459559
PD-L1 and PD-L2 Expression Levels Are Low in Primary and Secondary Adenoid Cystic Carcinomas of the Orbit: Therapeutic Implications.
Wolkow N, Jakobiec FA, Afrogheh AH, Kidd M, Eagle RC, Pai SI, Faquin WC
Ophthalmic Plast Reconstr Surg 2020 Sep/Oct;36(5):444-450. doi: 10.1097/IOP.0000000000001585. PMID: 31990894Free PMC Article
Rising trends in cholangiocarcinoma: is the ICD classification system misleading us?
Khan SA, Emadossadaty S, Ladep NG, Thomas HC, Elliott P, Taylor-Robinson SD, Toledano MB
J Hepatol 2012 Apr;56(4):848-54. Epub 2011 Dec 13 doi: 10.1016/j.jhep.2011.11.015. PMID: 22173164
Management and outcome of recurrent well-differentiated thyroid carcinoma.
Palme CE, Waseem Z, Raza SN, Eski S, Walfish P, Freeman JL
Arch Otolaryngol Head Neck Surg 2004 Jul;130(7):819-24. doi: 10.1001/archotol.130.7.819. PMID: 15262757

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