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True ependymal rosette

MedGen UID:
1670942
•Concept ID:
C4732760
•
Finding
HPO: HP:0031928

Definition

A type of rosette in which a halo of cells surrounds an empty lumen. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTrue ependymal rosette

Recent clinical studies

Etiology

TP53, β-Catenin and c-myc/N-myc status in embryonal tumours with ependymoblastic rosettes.
Gessi M, Zur Muehlen A, Lauriola L, Gardiman MP, Giangaspero F, Pietsch T
Neuropathol Appl Neurobiol 2011 Jun;37(4):406-13. doi: 10.1111/j.1365-2990.2010.01151.x. PMID: 21073496

Diagnosis

Pigmented Ependymoma of the Fourth Ventricle-A Curious Entity: Report of a Rare Case With Review of Literature.
Malhotra A, Rao S, Santhoshkumar R, Muralidharan N, Mitra S, Shetty S
Int J Surg Pathol 2021 Feb;29(1):80-84. Epub 2020 May 25 doi: 10.1177/1066896920926700. PMID: 32450730
Cerebellar ependymoma with overlapping features of clear-cell and tanycytic variants mimicking hemangioblastoma: a case report and literature review.
Zhang XP, Liu Y, Zhang D, Zheng Q, Wang C, Wang L, Li QC, Qiu XS, Wang EH
Diagn Pathol 2017 Mar 20;12(1):28. doi: 10.1186/s13000-017-0619-2. PMID: 28320419Free PMC Article
Anaplastic ependymoma with ependymoblastic multilayered rosettes.
Nobusawa S, Suzuki A, Nagaishi M, Isoda K, Ikota H, Yokoo H, Hirato J, Nakazato Y
Hum Pathol 2013 Nov;44(11):2597-602. Epub 2013 Jun 18 doi: 10.1016/j.humpath.2013.03.012. PMID: 23791209
Papillary tumor of the pineal region: two case studies and a review of the literature.
Rickard KA, Parker JR, Vitaz TW, Plaga AR, Wagner S, Parker JC Jr
Ann Clin Lab Sci 2011 Spring;41(2):174-81. PMID: 21844577
Tanycytic ependymoma.
Langford LA, Barré GM
Ultrastruct Pathol 1997 Mar-Apr;21(2):135-42. doi: 10.3109/01913129709021312. PMID: 9090024

Prognosis

Cerebellar ependymoma with overlapping features of clear-cell and tanycytic variants mimicking hemangioblastoma: a case report and literature review.
Zhang XP, Liu Y, Zhang D, Zheng Q, Wang C, Wang L, Li QC, Qiu XS, Wang EH
Diagn Pathol 2017 Mar 20;12(1):28. doi: 10.1186/s13000-017-0619-2. PMID: 28320419Free PMC Article
Anaplastic ependymoma with ependymoblastic multilayered rosettes.
Nobusawa S, Suzuki A, Nagaishi M, Isoda K, Ikota H, Yokoo H, Hirato J, Nakazato Y
Hum Pathol 2013 Nov;44(11):2597-602. Epub 2013 Jun 18 doi: 10.1016/j.humpath.2013.03.012. PMID: 23791209
Anaplastic ependymoma simulating glioblastoma in the cerebrum of an adult.
Shintaku M, Hashimoto K
Brain Tumor Pathol 2012 Jan;29(1):31-6. Epub 2011 Jul 16 doi: 10.1007/s10014-011-0057-x. PMID: 21833575Free PMC Article
Papillary tumor of the pineal region: two case studies and a review of the literature.
Rickard KA, Parker JR, Vitaz TW, Plaga AR, Wagner S, Parker JC Jr
Ann Clin Lab Sci 2011 Spring;41(2):174-81. PMID: 21844577
Primary ependymoma of the mediastinum: a clinicopathologic study of three cases.
Wilson RW, Moran CA
Ann Diagn Pathol 1998 Oct;2(5):293-300. doi: 10.1016/s1092-9134(98)80021-x. PMID: 9845752

Clinical prediction guides

Cerebellar ependymoma with overlapping features of clear-cell and tanycytic variants mimicking hemangioblastoma: a case report and literature review.
Zhang XP, Liu Y, Zhang D, Zheng Q, Wang C, Wang L, Li QC, Qiu XS, Wang EH
Diagn Pathol 2017 Mar 20;12(1):28. doi: 10.1186/s13000-017-0619-2. PMID: 28320419Free PMC Article
Anaplastic ependymoma simulating glioblastoma in the cerebrum of an adult.
Shintaku M, Hashimoto K
Brain Tumor Pathol 2012 Jan;29(1):31-6. Epub 2011 Jul 16 doi: 10.1007/s10014-011-0057-x. PMID: 21833575Free PMC Article
Establishment and characterization of clinically relevant models of ependymoma: a true challenge for targeted therapy.
Guan S, Shen R, Lafortune T, Tiao N, Houghton P, Yung WK, Koul D
Neuro Oncol 2011 Jul;13(7):748-58. Epub 2011 Jun 8 doi: 10.1093/neuonc/nor037. PMID: 21653596Free PMC Article
Tanycytic ependymoma of the spinal cord with anaplastic cytological features.
Shintaku M, Nagata N, Itoh H
Brain Tumor Pathol 2009;26(1):7-10. Epub 2009 Apr 30 doi: 10.1007/s10014-008-0239-3. PMID: 19408091
Clear-cell ependymoma of the cerebellum: a case report.
Kim JH, Cho BK, Kim IO, Park SH
Ultrastruct Pathol 2007 May-Jun;31(3):241-7. doi: 10.1080/01913120701446841. PMID: 17614003

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