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Recurrent Renal Pelvis Urothelial Carcinoma

MedGen UID:
1670555
•Concept ID:
C4725797
•
Neoplastic Process

Definition

The reemergence of renal pelvis urothelial carcinoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Renal Pelvis Urothelial Carcinoma

Professional guidelines

PubMed

Long-term ureteroscopic management of upper tract urothelial carcinoma: 28-year single-centre experience.
Maruyama Y, Araki M, Wada K, Yoshinaga K, Mitsui Y, Sadahira T, Nishimura S, Edamura K, Kobayashi Y, Watanabe M, Watanabe T, Monga M, Nasu Y, Kumon H
Jpn J Clin Oncol 2021 Jan 1;51(1):130-137. doi: 10.1093/jjco/hyaa132. PMID: 32715306
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Diagnosis and management of urothelial carcinoma of the bladder.
Tanaka MF, Sonpavde G
Postgrad Med 2011 May;123(3):43-55. doi: 10.3810/pgm.2011.05.2283. PMID: 21566415

Recent clinical studies

Etiology

European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2023 Update.
Rouprêt M, Seisen T, Birtle AJ, Capoun O, Compérat EM, Dominguez-Escrig JL, Gürses Andersson I, Liedberg F, Mariappan P, Hugh Mostafid A, Pradere B, van Rhijn BWG, Shariat SF, Rai BP, Soria F, Soukup V, Wood RG, Xylinas EN, Masson-Lecomte A, Gontero P
Eur Urol 2023 Jul;84(1):49-64. Epub 2023 Mar 24 doi: 10.1016/j.eururo.2023.03.013. PMID: 36967359
Adjuvant Radiotherapy for Upper Tract Urothelial Carcinoma: Systematic Review and Meta-Analysis.
Zalay O, Yan M, Sigurdson S, Malone S, Vera-Badillo FE, Mahmud A
Curr Oncol 2022 Dec 20;30(1):19-36. doi: 10.3390/curroncol30010002. PMID: 36661651Free PMC Article
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Primary chemoablation of low-grade upper tract urothelial carcinoma using UGN-101, a mitomycin-containing reverse thermal gel (OLYMPUS): an open-label, single-arm, phase 3 trial.
Kleinmann N, Matin SF, Pierorazio PM, Gore JL, Shabsigh A, Hu B, Chamie K, Godoy G, Hubosky S, Rivera M, O'Donnell M, Quek M, Raman JD, Knoedler JJ, Scherr D, Stern J, Weight C, Weizer A, Woods M, Kaimakliotis H, Smith AB, Linehan J, Coleman J, Humphreys MR, Pak R, Lifshitz D, Verni M, Adibi M, Amin MB, Seltzer E, Klein I, Konorty M, Strauss-Ayali D, Hakim G, Schoenberg M, Lerner SP
Lancet Oncol 2020 Jun;21(6):776-785. Epub 2020 Apr 29 doi: 10.1016/S1470-2045(20)30147-9. PMID: 32631491
Diagnosis and management of urothelial carcinoma of the bladder.
Tanaka MF, Sonpavde G
Postgrad Med 2011 May;123(3):43-55. doi: 10.3810/pgm.2011.05.2283. PMID: 21566415

Diagnosis

Imaging of Upper Tract Urothelial Carcinoma.
Nakai H, Takahashi H, Wellnitz CV, Stanton ML, Takahashi N, Kawashima A
Radiographics 2024 Nov;44(11):e240056. doi: 10.1148/rg.240056. PMID: 39480700
Design and rationale of a single-arm phase II study of neoadjuvant Durvalumab and Gemcitabine associated with Cisplatin or Carboplatin for upper urinary tract urothelial cancer: the iNDUCT trial (NCT04617756).
Calleris G, Rouprêt M, Seisen T, Bendjeddou L, Chevallier T, Masson-Lecomte A, Thibault C, Neuzillet Y, Audenet F, Xylinas E, Houédé N
World J Urol 2023 Dec;41(12):3413-3420. Epub 2023 Sep 12 doi: 10.1007/s00345-023-04596-5. PMID: 37698632
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2023 Update.
Rouprêt M, Seisen T, Birtle AJ, Capoun O, Compérat EM, Dominguez-Escrig JL, Gürses Andersson I, Liedberg F, Mariappan P, Hugh Mostafid A, Pradere B, van Rhijn BWG, Shariat SF, Rai BP, Soria F, Soukup V, Wood RG, Xylinas EN, Masson-Lecomte A, Gontero P
Eur Urol 2023 Jul;84(1):49-64. Epub 2023 Mar 24 doi: 10.1016/j.eururo.2023.03.013. PMID: 36967359
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Diagnosis and management of urothelial carcinoma of the bladder.
Tanaka MF, Sonpavde G
Postgrad Med 2011 May;123(3):43-55. doi: 10.3810/pgm.2011.05.2283. PMID: 21566415

Therapy

Design and rationale of a single-arm phase II study of neoadjuvant Durvalumab and Gemcitabine associated with Cisplatin or Carboplatin for upper urinary tract urothelial cancer: the iNDUCT trial (NCT04617756).
Calleris G, Rouprêt M, Seisen T, Bendjeddou L, Chevallier T, Masson-Lecomte A, Thibault C, Neuzillet Y, Audenet F, Xylinas E, Houédé N
World J Urol 2023 Dec;41(12):3413-3420. Epub 2023 Sep 12 doi: 10.1007/s00345-023-04596-5. PMID: 37698632
Adjuvant Radiotherapy for Upper Tract Urothelial Carcinoma: Systematic Review and Meta-Analysis.
Zalay O, Yan M, Sigurdson S, Malone S, Vera-Badillo FE, Mahmud A
Curr Oncol 2022 Dec 20;30(1):19-36. doi: 10.3390/curroncol30010002. PMID: 36661651Free PMC Article
Primary chemoablation of low-grade upper tract urothelial carcinoma using UGN-101, a mitomycin-containing reverse thermal gel (OLYMPUS): an open-label, single-arm, phase 3 trial.
Kleinmann N, Matin SF, Pierorazio PM, Gore JL, Shabsigh A, Hu B, Chamie K, Godoy G, Hubosky S, Rivera M, O'Donnell M, Quek M, Raman JD, Knoedler JJ, Scherr D, Stern J, Weight C, Weizer A, Woods M, Kaimakliotis H, Smith AB, Linehan J, Coleman J, Humphreys MR, Pak R, Lifshitz D, Verni M, Adibi M, Amin MB, Seltzer E, Klein I, Konorty M, Strauss-Ayali D, Hakim G, Schoenberg M, Lerner SP
Lancet Oncol 2020 Jun;21(6):776-785. Epub 2020 Apr 29 doi: 10.1016/S1470-2045(20)30147-9. PMID: 32631491
Salvage topical therapy for upper tract urothelial carcinoma.
Balasubramanian A, Metcalfe MJ, Wagenheim G, Xiao L, Papadopoulos J, Navai N, Davis JW, Karam JA, Kamat AM, Wood CG, Dinney CP, Matin SF
World J Urol 2018 Dec;36(12):2027-2034. Epub 2018 May 26 doi: 10.1007/s00345-018-2349-9. PMID: 29804202Free PMC Article
Diagnosis and management of urothelial carcinoma of the bladder.
Tanaka MF, Sonpavde G
Postgrad Med 2011 May;123(3):43-55. doi: 10.3810/pgm.2011.05.2283. PMID: 21566415

Prognosis

European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2023 Update.
Rouprêt M, Seisen T, Birtle AJ, Capoun O, Compérat EM, Dominguez-Escrig JL, Gürses Andersson I, Liedberg F, Mariappan P, Hugh Mostafid A, Pradere B, van Rhijn BWG, Shariat SF, Rai BP, Soria F, Soukup V, Wood RG, Xylinas EN, Masson-Lecomte A, Gontero P
Eur Urol 2023 Jul;84(1):49-64. Epub 2023 Mar 24 doi: 10.1016/j.eururo.2023.03.013. PMID: 36967359
Cohort profile: Bladder Cancer Data Base Sweden (BladderBaSe) 2.0.
Häggström C, Hagberg O, Gårdmark T, Aljabery F, Ströck V, Hosseini A, Sherif A, Malmstrom PU, Söderkvist K, Ullén A, Jerlström T, Jahnson S, Liedberg F, Holmberg L
BMJ Open 2022 Dec 20;12(12):e064898. doi: 10.1136/bmjopen-2022-064898. PMID: 36600418Free PMC Article
European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Systematic Review on the Fate of the Remnant Urothelium after Radical Cystectomy.
Gakis G, Black PC, Bochner BH, Boorjian SA, Stenzl A, Thalmann GN, Kassouf W
Eur Urol 2017 Apr;71(4):545-557. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.035. PMID: 27720534Free PMC Article
Prognostic factors and predictive tools for upper tract urothelial carcinoma: a systematic review.
Mbeutcha A, Rouprêt M, Kamat AM, Karakiewicz PI, Lawrentschuk N, Novara G, Raman JD, Seitz C, Xylinas E, Shariat SF
World J Urol 2017 Mar;35(3):337-353. Epub 2016 Apr 21 doi: 10.1007/s00345-016-1826-2. PMID: 27101100

Clinical prediction guides

Primary chemoablation of low-grade upper tract urothelial carcinoma using UGN-101, a mitomycin-containing reverse thermal gel (OLYMPUS): an open-label, single-arm, phase 3 trial.
Kleinmann N, Matin SF, Pierorazio PM, Gore JL, Shabsigh A, Hu B, Chamie K, Godoy G, Hubosky S, Rivera M, O'Donnell M, Quek M, Raman JD, Knoedler JJ, Scherr D, Stern J, Weight C, Weizer A, Woods M, Kaimakliotis H, Smith AB, Linehan J, Coleman J, Humphreys MR, Pak R, Lifshitz D, Verni M, Adibi M, Amin MB, Seltzer E, Klein I, Konorty M, Strauss-Ayali D, Hakim G, Schoenberg M, Lerner SP
Lancet Oncol 2020 Jun;21(6):776-785. Epub 2020 Apr 29 doi: 10.1016/S1470-2045(20)30147-9. PMID: 32631491
Case 258: Granulomatous Prostatitis.
Diaz de Leon A, Costa DN, Francis F, Pedrosa I
Radiology 2018 Oct;289(1):267-271. doi: 10.1148/radiol.2018161272. PMID: 30230997
Prognostic Factors and Risk Stratification in Invasive Upper Tract Urothelial Carcinoma.
Emamekhoo H, Dhillon P, Gopalakrishnan D, Elson P, Stephenson A, Magi-Galluzzi C, McKenney J, Harper H, Haber GP, Kaouk J, Lee B, Fergany A, Berglund R, Gong M, Stein R, Krishnamurthi V, Gilligan T, Ornstein M, Rini B, Garcia J, Grivas P
Clin Genitourin Cancer 2018 Aug;16(4):e751-e760. Epub 2018 Feb 6 doi: 10.1016/j.clgc.2018.01.014. PMID: 29551583
Nephrogenic adenoma of the urinary tract: A 6-year single center experience.
Turcan D, Acikalin MF, Yilmaz E, Canaz F, Arik D
Pathol Res Pract 2017 Jul;213(7):831-835. Epub 2017 Mar 25 doi: 10.1016/j.prp.2017.03.001. PMID: 28554748
Prognostic factors and predictive tools for upper tract urothelial carcinoma: a systematic review.
Mbeutcha A, Rouprêt M, Kamat AM, Karakiewicz PI, Lawrentschuk N, Novara G, Raman JD, Seitz C, Xylinas E, Shariat SF
World J Urol 2017 Mar;35(3):337-353. Epub 2016 Apr 21 doi: 10.1007/s00345-016-1826-2. PMID: 27101100

Recent systematic reviews

Adjuvant Radiotherapy for Upper Tract Urothelial Carcinoma: Systematic Review and Meta-Analysis.
Zalay O, Yan M, Sigurdson S, Malone S, Vera-Badillo FE, Mahmud A
Curr Oncol 2022 Dec 20;30(1):19-36. doi: 10.3390/curroncol30010002. PMID: 36661651Free PMC Article
Systematic Review on the Fate of the Remnant Urothelium after Radical Cystectomy.
Gakis G, Black PC, Bochner BH, Boorjian SA, Stenzl A, Thalmann GN, Kassouf W
Eur Urol 2017 Apr;71(4):545-557. Epub 2016 Oct 6 doi: 10.1016/j.eururo.2016.09.035. PMID: 27720534Free PMC Article
Prognostic factors and predictive tools for upper tract urothelial carcinoma: a systematic review.
Mbeutcha A, Rouprêt M, Kamat AM, Karakiewicz PI, Lawrentschuk N, Novara G, Raman JD, Seitz C, Xylinas E, Shariat SF
World J Urol 2017 Mar;35(3):337-353. Epub 2016 Apr 21 doi: 10.1007/s00345-016-1826-2. PMID: 27101100
Oncologic Outcomes of Kidney-sparing Surgery Versus Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: A Systematic Review by the EAU Non-muscle Invasive Bladder Cancer Guidelines Panel.
Seisen T, Peyronnet B, Dominguez-Escrig JL, Bruins HM, Yuan CY, Babjuk M, Böhle A, Burger M, Compérat EM, Cowan NC, Kaasinen E, Palou J, van Rhijn BW, Sylvester RJ, Zigeuner R, Shariat SF, Rouprêt M
Eur Urol 2016 Dec;70(6):1052-1068. Epub 2016 Jul 28 doi: 10.1016/j.eururo.2016.07.014. PMID: 27477528
A Systematic Review and Meta-analysis of Clinicopathologic Factors Linked to Intravesical Recurrence After Radical Nephroureterectomy to Treat Upper Tract Urothelial Carcinoma.
Seisen T, Granger B, Colin P, Léon P, Utard G, Renard-Penna R, Compérat E, Mozer P, Cussenot O, Shariat SF, Rouprêt M
Eur Urol 2015 Jun;67(6):1122-1133. Epub 2014 Dec 6 doi: 10.1016/j.eururo.2014.11.035. PMID: 25488681

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