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Necrotic uveal melanoma

MedGen UID:
1669717
•Concept ID:
C0279695
•
Neoplastic Process
Synonyms: Necrotic Uveal Melanoma; necrotic uveal melanoma; Uveal Necrotic Melanoma
 
Monarch Initiative: MONDO:0004365

Definition

A uveal melanoma characterized by the presence of tumor cell necrosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNecrotic uveal melanoma

Professional guidelines

PubMed

Vitreoretinal Surgery in the Prevention and Treatment of Toxic Tumour Syndrome in Uveal Melanoma: A Systematic Review.
Romano MR, Catania F, Confalonieri F, Zollet P, Allegrini D, Sergenti J, Lanza FB, Ferrara M, Angi M
Int J Mol Sci 2021 Sep 17;22(18) doi: 10.3390/ijms221810066. PMID: 34576231Free PMC Article
Scleral patch grafts in the management of uveal and ocular surface tumors.
Barman M, Finger PT, Milman T
Ophthalmology 2012 Dec;119(12):2631-6. Epub 2012 Aug 1 doi: 10.1016/j.ophtha.2012.06.024. PMID: 22858126
Apoptotic response of uveal melanoma cells upon treatment with chelidonine, sanguinarine and chelerythrine.
Kemény-Beke A, Aradi J, Damjanovich J, Beck Z, Facskó A, Berta A, Bodnár A
Cancer Lett 2006 Jun 8;237(1):67-75. Epub 2005 Jul 12 doi: 10.1016/j.canlet.2005.05.037. PMID: 16019128

Recent clinical studies

Diagnosis

Necrosis of uveal melanoma post-COVID-19 vaccination.
Wagle AM, Wu BC, Gopal L, Sundar G
Indian J Ophthalmol 2022 May;70(5):1837-1840. doi: 10.4103/ijo.IJO_3040_21. PMID: 35502089Free PMC Article
DIAGNOSTIC CHALLENGES IN NECROTIC UVEAL MELANOMA.
Peddada K, Dalvin LA, Mashayekhi A, Shields CL
Retin Cases Brief Rep 2022 Jan 1;16(1):92-94. doi: 10.1097/ICB.0000000000000913. PMID: 31425450
Concurrence of peripunctal nevus and uveal melanoma with scleral pigment dispersion presenting as phthisis bulbi.
Ghose N, Vempuluru VS, Jakati S, Kaliki S
BMJ Case Rep 2021 Apr 16;14(4) doi: 10.1136/bcr-2020-240854. PMID: 33863771Free PMC Article
Necrotic uveal melanoma with orbital inflammation.
Blasi MA, Giammaria D, Balestrazzi E
Eur J Ophthalmol 2006 Jul-Aug;16(4):647-50. doi: 10.1177/112067210601600429. PMID: 16952114

Therapy

Necrosis of uveal melanoma post-COVID-19 vaccination.
Wagle AM, Wu BC, Gopal L, Sundar G
Indian J Ophthalmol 2022 May;70(5):1837-1840. doi: 10.4103/ijo.IJO_3040_21. PMID: 35502089Free PMC Article
Early-onset scleral necrosis after iodine I 125 plaque radiotherapy for ciliochoroidal melanoma.
Corrêa ZM, Augsburger JJ, Freire J, Eagle RC Jr
Arch Ophthalmol 1999 Feb;117(2):259-61. doi: 10.1001/archopht.117.2.259. PMID: 10037576

Prognosis

DIAGNOSTIC CHALLENGES IN NECROTIC UVEAL MELANOMA.
Peddada K, Dalvin LA, Mashayekhi A, Shields CL
Retin Cases Brief Rep 2022 Jan 1;16(1):92-94. doi: 10.1097/ICB.0000000000000913. PMID: 31425450

Clinical prediction guides

Lipid crystals in malignant melanoma of the choroid.
Margo CE, Pusateri TJ, Ulshafer RJ, Keller RK
Retina 1990;10(1):68-71. PMID: 2343196

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