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Linear focal dermal elastosis

MedGen UID:
1666729
Concept ID:
C4751166
Disease or Syndrome
Synonyms: Elastotic striae; linear focal dermal elastosis; Linear focal elastosis; linear focal elastosis
SNOMED CT: Linear focal elastosis (773697006); Elastotic striae (773697006); Linear focal dermal elastosis (773697006)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0016438
Orphanet: ORPHA228236

Definition

A rare acquired dermis elastic tissue disorder characterised by asymptomatic palpable hypertrophic or atrophic, yellowish or red, indurated, horizontal, striae-like linear plaques distributed symmetrically across the mid and lower back. No systemic involvement has been described. Skin biopsy reveals a focal increase in abnormal elastic tissue with abundant wavy, fragmented and aggregated basophilic elastic fibres in the reticular dermis. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLinear focal dermal elastosis

Recent clinical studies

Diagnosis

Andrés-Ramos I, Alegría-Landa V, Gimeno I, Pérez-Plaza A, Rütten A, Kutzner H, Requena L
Am J Dermatopathol 2019 Feb;41(2):85-117. doi: 10.1097/DAD.0000000000001275. PMID: 30688725
Higgins HJ, Whitworth MW
Cutis 2010 Apr;85(4):195-7. PMID: 20486459
Lewis KG, Bercovitch L, Dill SW, Robinson-Bostom L
J Am Acad Dermatol 2004 Jul;51(1):1-21; quiz 22-4. doi: 10.1016/j.jaad.2004.03.013. PMID: 15243519
Pui JC, Arroyo M, Heintz P
J Drugs Dermatol 2003 Jan;2(1):79-83. PMID: 12852387
Moiin A, Hashimoto K
J Am Acad Dermatol 1994 May;30(5 Pt 2):874-7. doi: 10.1016/s0190-9622(94)70103-2. PMID: 8169266

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