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Locally Advanced Prostate Adenocarcinoma

MedGen UID:
1662547
•Concept ID:
C4744715
•
Neoplastic Process

Definition

A prostatic adenocarcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Prostate Adenocarcinoma

Professional guidelines

PubMed

Treatment-related Neuroendocrine Prostate Carcinoma-Diagnostic and Molecular Correlates.
Gopalan A
Adv Anat Pathol 2024 Mar 1;31(2):70-79. Epub 2024 Jan 15 doi: 10.1097/PAP.0000000000000431. PMID: 38223983
Surgical Management and Considerations for Patients with Localized High-Risk Prostate Cancer.
Fang AM, Jackson J, Gregg JR, Chery L, Tang C, Surasi DS, Siddiqui BA, Rais-Bahrami S, Bathala T, Chapin BF
Curr Treat Options Oncol 2024 Jan;25(1):66-83. Epub 2024 Jan 3 doi: 10.1007/s11864-023-01162-4. PMID: 38212510
Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol.
Attard G, Murphy L, Clarke NW, Cross W, Jones RJ, Parker CC, Gillessen S, Cook A, Brawley C, Amos CL, Atako N, Pugh C, Buckner M, Chowdhury S, Malik Z, Russell JM, Gilson C, Rush H, Bowen J, Lydon A, Pedley I, O'Sullivan JM, Birtle A, Gale J, Srihari N, Thomas C, Tanguay J, Wagstaff J, Das P, Gray E, Alzoueb M, Parikh O, Robinson A, Syndikus I, Wylie J, Zarkar A, Thalmann G, de Bono JS, Dearnaley DP, Mason MD, Gilbert D, Langley RE, Millman R, Matheson D, Sydes MR, Brown LC, Parmar MKB, James ND; Systemic Therapy in Advancing or Metastatic Prostate cancer: Evaluation of Drug Efficacy (STAMPEDE) investigators
Lancet 2022 Jan 29;399(10323):447-460. Epub 2021 Dec 23 doi: 10.1016/S0140-6736(21)02437-5. PMID: 34953525Free PMC Article

Recent clinical studies

Etiology

Influence of Humoral Response Against GnRH, Generated by Immunization with a Therapeutic Vaccine Candidate on the Evolution of Patients with Castration-Sensitive Prostate Adenocarcinoma.
Campal-Espinosa AC, Junco-Barranco JA, Fuentes-Aguilar F, Calzada-Aguilera L, Rivacoba-Betancourt A, Rodríguez-Bueno RH, Bover-Campal AC, Bover-Fuentes EE, González L, de Quesada L, Alvarez A, Garay-Pérez HE
Technol Cancer Res Treat 2023 Jan-Dec;22:15330338231207318. doi: 10.1177/15330338231207318. PMID: 37828833Free PMC Article
Extracorporeal hemoadsorption therapy as a potential therapeutic option for rapid removal of Apixaban in high risk-surgical patients: a case report.
Dalmastri V, Angelini A, Minerva V, Ballarini M, Grammatico F, Todeschini P, Pizzini AM, Silingardi M, La Manna G
J Med Case Rep 2023 Jul 7;17(1):283. doi: 10.1186/s13256-023-03949-3. PMID: 37415195Free PMC Article
Dose-escalated radiotherapy for clinically localized and locally advanced prostate cancer.
Kim S, Kong JH, Lee Y, Lee JY, Kang TW, Kong TH, Kim MH, You SH
Cochrane Database Syst Rev 2023 Mar 8;3(3):CD012817. doi: 10.1002/14651858.CD012817.pub2. PMID: 36884035Free PMC Article
Acute myeloid leukemia incidence following radiation therapy for localized or locally advanced prostate adenocarcinoma.
Ojha RP, Fischbach LA, Zhou Y, Felini MJ, Singh KP, Thertulien R
Cancer Epidemiol 2010 Jun;34(3):274-8. Epub 2010 Apr 27 doi: 10.1016/j.canep.2010.04.003. PMID: 20427255
Quality of life in men with locally advanced adenocarcinoma of the prostate: an exploratory analysis using data from the CaPSURE database.
White WM, Sadetsky N, Waters WB, Carroll PR, Litwin MS
J Urol 2008 Dec;180(6):2409-13; discussion 2414. Epub 2008 Oct 18 doi: 10.1016/j.juro.2008.08.079. PMID: 18930270

Diagnosis

Granulomatous prostatitis: mimicking locally advanced prostate adenocarcinoma.
Mannatrizio D, Eusebi L, Yehia M, Filosa A, Guglielmi G
Acta Biomed 2023 Oct 17;94(5):e2023245. doi: 10.23750/abm.v94i5.13751. PMID: 37850783Free PMC Article
Influence of Humoral Response Against GnRH, Generated by Immunization with a Therapeutic Vaccine Candidate on the Evolution of Patients with Castration-Sensitive Prostate Adenocarcinoma.
Campal-Espinosa AC, Junco-Barranco JA, Fuentes-Aguilar F, Calzada-Aguilera L, Rivacoba-Betancourt A, Rodríguez-Bueno RH, Bover-Campal AC, Bover-Fuentes EE, González L, de Quesada L, Alvarez A, Garay-Pérez HE
Technol Cancer Res Treat 2023 Jan-Dec;22:15330338231207318. doi: 10.1177/15330338231207318. PMID: 37828833Free PMC Article
Acute myeloid leukemia incidence following radiation therapy for localized or locally advanced prostate adenocarcinoma.
Ojha RP, Fischbach LA, Zhou Y, Felini MJ, Singh KP, Thertulien R
Cancer Epidemiol 2010 Jun;34(3):274-8. Epub 2010 Apr 27 doi: 10.1016/j.canep.2010.04.003. PMID: 20427255
Quality of life in men with locally advanced adenocarcinoma of the prostate: an exploratory analysis using data from the CaPSURE database.
White WM, Sadetsky N, Waters WB, Carroll PR, Litwin MS
J Urol 2008 Dec;180(6):2409-13; discussion 2414. Epub 2008 Oct 18 doi: 10.1016/j.juro.2008.08.079. PMID: 18930270

Therapy

Influence of Humoral Response Against GnRH, Generated by Immunization with a Therapeutic Vaccine Candidate on the Evolution of Patients with Castration-Sensitive Prostate Adenocarcinoma.
Campal-Espinosa AC, Junco-Barranco JA, Fuentes-Aguilar F, Calzada-Aguilera L, Rivacoba-Betancourt A, Rodríguez-Bueno RH, Bover-Campal AC, Bover-Fuentes EE, González L, de Quesada L, Alvarez A, Garay-Pérez HE
Technol Cancer Res Treat 2023 Jan-Dec;22:15330338231207318. doi: 10.1177/15330338231207318. PMID: 37828833Free PMC Article
Extracorporeal hemoadsorption therapy as a potential therapeutic option for rapid removal of Apixaban in high risk-surgical patients: a case report.
Dalmastri V, Angelini A, Minerva V, Ballarini M, Grammatico F, Todeschini P, Pizzini AM, Silingardi M, La Manna G
J Med Case Rep 2023 Jul 7;17(1):283. doi: 10.1186/s13256-023-03949-3. PMID: 37415195Free PMC Article
Dose-escalated radiotherapy for clinically localized and locally advanced prostate cancer.
Kim S, Kong JH, Lee Y, Lee JY, Kang TW, Kong TH, Kim MH, You SH
Cochrane Database Syst Rev 2023 Mar 8;3(3):CD012817. doi: 10.1002/14651858.CD012817.pub2. PMID: 36884035Free PMC Article
Neoadjuvant docetaxel/estramustine prior to radical prostatectomy or external beam radiotherapy in high risk localized prostate cancer: a phase II trial.
Kim WY, Whang YE, Pruthi RS, Baggstrom MQ, Rathmell WK, Rosenman JG, Wallen EM, Goyal LK, Grigson G, Watkins C, Godley PA
Urol Oncol 2011 Nov-Dec;29(6):608-13. Epub 2009 Dec 21 doi: 10.1016/j.urolonc.2009.09.012. PMID: 20022268
Late urinary morbidity with high dose prostate brachytherapy as a boost to conventional external beam radiation therapy for local and locally advanced prostate cancer.
Pellizzon AC, Salvajoli JV, Maia MA, Ferrigno R, Novaes PE, Fogarolli RC, Pellizzon RJ
J Urol 2004 Mar;171(3):1105-8. doi: 10.1097/01.ju.0000113260.07979.d3. PMID: 14767280

Prognosis

Extracorporeal hemoadsorption therapy as a potential therapeutic option for rapid removal of Apixaban in high risk-surgical patients: a case report.
Dalmastri V, Angelini A, Minerva V, Ballarini M, Grammatico F, Todeschini P, Pizzini AM, Silingardi M, La Manna G
J Med Case Rep 2023 Jul 7;17(1):283. doi: 10.1186/s13256-023-03949-3. PMID: 37415195Free PMC Article
Acute myeloid leukemia incidence following radiation therapy for localized or locally advanced prostate adenocarcinoma.
Ojha RP, Fischbach LA, Zhou Y, Felini MJ, Singh KP, Thertulien R
Cancer Epidemiol 2010 Jun;34(3):274-8. Epub 2010 Apr 27 doi: 10.1016/j.canep.2010.04.003. PMID: 20427255
Late urinary morbidity with high dose prostate brachytherapy as a boost to conventional external beam radiation therapy for local and locally advanced prostate cancer.
Pellizzon AC, Salvajoli JV, Maia MA, Ferrigno R, Novaes PE, Fogarolli RC, Pellizzon RJ
J Urol 2004 Mar;171(3):1105-8. doi: 10.1097/01.ju.0000113260.07979.d3. PMID: 14767280

Clinical prediction guides

Influence of Humoral Response Against GnRH, Generated by Immunization with a Therapeutic Vaccine Candidate on the Evolution of Patients with Castration-Sensitive Prostate Adenocarcinoma.
Campal-Espinosa AC, Junco-Barranco JA, Fuentes-Aguilar F, Calzada-Aguilera L, Rivacoba-Betancourt A, Rodríguez-Bueno RH, Bover-Campal AC, Bover-Fuentes EE, González L, de Quesada L, Alvarez A, Garay-Pérez HE
Technol Cancer Res Treat 2023 Jan-Dec;22:15330338231207318. doi: 10.1177/15330338231207318. PMID: 37828833Free PMC Article
Peritoneal Carcinomatosis From Metastatic Prostate Cancer Identified on 68 Ga-Prostate-Specific Membrane Antigen PET/CT.
Lau KS, Le K, Bui C, Wong VCK, Mansberg R
Clin Nucl Med 2023 Aug 1;48(8):704-706. Epub 2023 Jun 8 doi: 10.1097/RLU.0000000000004734. PMID: 37290423
Quality of life in men with locally advanced adenocarcinoma of the prostate: an exploratory analysis using data from the CaPSURE database.
White WM, Sadetsky N, Waters WB, Carroll PR, Litwin MS
J Urol 2008 Dec;180(6):2409-13; discussion 2414. Epub 2008 Oct 18 doi: 10.1016/j.juro.2008.08.079. PMID: 18930270
Late urinary morbidity with high dose prostate brachytherapy as a boost to conventional external beam radiation therapy for local and locally advanced prostate cancer.
Pellizzon AC, Salvajoli JV, Maia MA, Ferrigno R, Novaes PE, Fogarolli RC, Pellizzon RJ
J Urol 2004 Mar;171(3):1105-8. doi: 10.1097/01.ju.0000113260.07979.d3. PMID: 14767280

Recent systematic reviews

Dose-escalated radiotherapy for clinically localized and locally advanced prostate cancer.
Kim S, Kong JH, Lee Y, Lee JY, Kang TW, Kong TH, Kim MH, You SH
Cochrane Database Syst Rev 2023 Mar 8;3(3):CD012817. doi: 10.1002/14651858.CD012817.pub2. PMID: 36884035Free PMC Article

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