U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Refractory Malignant Soft Tissue Neoplasm

MedGen UID:
1652605
Concept ID:
C4725813
Neoplastic Process

Definition

Malignant soft tissue neoplasm that is resistant to treatment. [from NCI]

Professional guidelines

PubMed

Fujiwara T, Kunisada T, Nakata E, Nishida K, Yanai H, Nakamura T, Tanaka K, Ozaki T
Jpn J Clin Oncol 2023 Nov 5;53(11):1009-1018. doi: 10.1093/jjco/hyad102. PMID: 37626447Free PMC Article
Naito Y, Nishida T, Doi T
Gastric Cancer 2023 May;26(3):339-351. Epub 2023 Mar 13 doi: 10.1007/s10120-023-01381-6. PMID: 36913072Free PMC Article
Cheville AL, Smith SR, Basford JR
Hematol Oncol Clin North Am 2018 Jun;32(3):469-482. Epub 2018 Mar 17 doi: 10.1016/j.hoc.2018.02.001. PMID: 29729782

Recent clinical studies

Etiology

Qadir M, Fatima S, Shaikh S, Zeeshan S
BMJ Case Rep 2024 Apr 11;17(4) doi: 10.1136/bcr-2023-258846. PMID: 38604740Free PMC Article
Naito Y, Nishida T, Doi T
Gastric Cancer 2023 May;26(3):339-351. Epub 2023 Mar 13 doi: 10.1007/s10120-023-01381-6. PMID: 36913072Free PMC Article
Bladé J, Beksac M, Caers J, Jurczyszyn A, von Lilienfeld-Toal M, Moreau P, Rasche L, Rosiñol L, Usmani SZ, Zamagni E, Richardson P
Blood Cancer J 2022 Mar 21;12(3):45. doi: 10.1038/s41408-022-00643-3. PMID: 35314675Free PMC Article
Tsuchiya R, Yoshimatsu Y, Noguchi R, Sin Y, Ono T, Akiyama T, Sugaya J, Nakatani F, Kojima N, Yoshida A, Ohtori S, Kawai A, Kondo T
Hum Cell 2022 Jan;35(1):384-391. Epub 2021 Oct 19 doi: 10.1007/s13577-021-00633-w. PMID: 34665443
Defachelles AS, Bogart E, Casanova M, Merks JHM, Bisogno G, Calareso G, Gallego Melcon S, Gatz SA, Le Deley MC, McHugh K, Probst A, Rocourt N, van Rijn RR, Wheatley K, Minard-Colin V, Chisholm JC
J Clin Oncol 2021 Sep 20;39(27):2979-2990. Epub 2021 Aug 3 doi: 10.1200/JCO.21.00124. PMID: 34343032

Diagnosis

Qadir M, Fatima S, Shaikh S, Zeeshan S
BMJ Case Rep 2024 Apr 11;17(4) doi: 10.1136/bcr-2023-258846. PMID: 38604740Free PMC Article
Fujiwara T, Kunisada T, Nakata E, Nishida K, Yanai H, Nakamura T, Tanaka K, Ozaki T
Jpn J Clin Oncol 2023 Nov 5;53(11):1009-1018. doi: 10.1093/jjco/hyad102. PMID: 37626447Free PMC Article
Bladé J, Beksac M, Caers J, Jurczyszyn A, von Lilienfeld-Toal M, Moreau P, Rasche L, Rosiñol L, Usmani SZ, Zamagni E, Richardson P
Blood Cancer J 2022 Mar 21;12(3):45. doi: 10.1038/s41408-022-00643-3. PMID: 35314675Free PMC Article
Velez-Ruiz NJ, Klein JP
Semin Neurol 2012 Sep;32(4):361-73. Epub 2013 Jan 29 doi: 10.1055/s-0032-1331809. PMID: 23361482
Lazar MA, Kwon YW, Rokito AS
J Bone Joint Surg Am 2009 Sep;91(9):2251-62. doi: 10.2106/JBJS.H.01347. PMID: 19724005

Therapy

Naito Y, Nishida T, Doi T
Gastric Cancer 2023 May;26(3):339-351. Epub 2023 Mar 13 doi: 10.1007/s10120-023-01381-6. PMID: 36913072Free PMC Article
Zhang B, Zhang M, Shen C, Liu G, Zhang F, Hou J, Yao W
Cell Death Dis 2021 Sep 20;12(10):856. doi: 10.1038/s41419-021-04144-2. PMID: 34545063Free PMC Article
Defachelles AS, Bogart E, Casanova M, Merks JHM, Bisogno G, Calareso G, Gallego Melcon S, Gatz SA, Le Deley MC, McHugh K, Probst A, Rocourt N, van Rijn RR, Wheatley K, Minard-Colin V, Chisholm JC
J Clin Oncol 2021 Sep 20;39(27):2979-2990. Epub 2021 Aug 3 doi: 10.1200/JCO.21.00124. PMID: 34343032
Hegde M, Joseph SK, Pashankar F, DeRenzo C, Sanber K, Navai S, Byrd TT, Hicks J, Xu ML, Gerken C, Kalra M, Robertson C, Zhang H, Shree A, Mehta B, Dakhova O, Salsman VS, Grilley B, Gee A, Dotti G, Heslop HE, Brenner MK, Wels WS, Gottschalk S, Ahmed N
Nat Commun 2020 Jul 15;11(1):3549. doi: 10.1038/s41467-020-17175-8. PMID: 32669548Free PMC Article
Subbiah V, Kurzrock R
Curr Opin Oncol 2011 Jul;23(4):352-60. doi: 10.1097/CCO.0b013e3283477a94. PMID: 21519259

Prognosis

Naito Y, Nishida T, Doi T
Gastric Cancer 2023 May;26(3):339-351. Epub 2023 Mar 13 doi: 10.1007/s10120-023-01381-6. PMID: 36913072Free PMC Article
Hattinger CM, Salaroglio IC, Fantoni L, Godel M, Casotti C, Kopecka J, Scotlandi K, Ibrahim T, Riganti C, Serra M
Int J Mol Sci 2023 Jan 2;24(1) doi: 10.3390/ijms24010799. PMID: 36614241Free PMC Article
Bladé J, Beksac M, Caers J, Jurczyszyn A, von Lilienfeld-Toal M, Moreau P, Rasche L, Rosiñol L, Usmani SZ, Zamagni E, Richardson P
Blood Cancer J 2022 Mar 21;12(3):45. doi: 10.1038/s41408-022-00643-3. PMID: 35314675Free PMC Article
Tsuchiya R, Yoshimatsu Y, Noguchi R, Sin Y, Ono T, Akiyama T, Sugaya J, Nakatani F, Kojima N, Yoshida A, Ohtori S, Kawai A, Kondo T
Hum Cell 2022 Jan;35(1):384-391. Epub 2021 Oct 19 doi: 10.1007/s13577-021-00633-w. PMID: 34665443
Subbiah V, Kurzrock R
Curr Opin Oncol 2011 Jul;23(4):352-60. doi: 10.1097/CCO.0b013e3283477a94. PMID: 21519259

Clinical prediction guides

Zheng W, Xue Q, Sha X, Wang Y, Wang Y, Liu J, Zhang Y, Shi W
Cancer Biol Ther 2021 Dec 2;22(10-12):537-543. Epub 2021 Sep 27 doi: 10.1080/15384047.2021.1967083. PMID: 34570671Free PMC Article
Dwyer AR, Kerkvliet CP, Krutilina RI, Playa HC, Parke DN, Thomas WA, Smeester BA, Moriarity BS, Seagroves TN, Lange CA
Mol Cancer Res 2021 Feb;19(2):329-345. Epub 2020 Nov 10 doi: 10.1158/1541-7786.MCR-20-0295. PMID: 33172975Free PMC Article
Stacchiotti S, Pantaleo MA, Astolfi A, Dagrada GP, Negri T, Dei Tos AP, Indio V, Morosi C, Gronchi A, Colombo C, Conca E, Toffolatti L, Tazzari M, Crippa F, Maestro R, Pilotti S, Casali PG
Eur J Cancer 2014 Jun;50(9):1657-64. Epub 2014 Apr 2 doi: 10.1016/j.ejca.2014.03.013. PMID: 24703573
Scher HI, Halabi S, Tannock I, Morris M, Sternberg CN, Carducci MA, Eisenberger MA, Higano C, Bubley GJ, Dreicer R, Petrylak D, Kantoff P, Basch E, Kelly WK, Figg WD, Small EJ, Beer TM, Wilding G, Martin A, Hussain M; Prostate Cancer Clinical Trials Working Group
J Clin Oncol 2008 Mar 1;26(7):1148-59. doi: 10.1200/JCO.2007.12.4487. PMID: 18309951Free PMC Article
Bladé J, Perales M, Rosiñol L, Tuset M, Montoto S, Esteve J, Cobo F, Villela L, Rafel M, Nomdedeu B, Montserrat E
Br J Haematol 2001 May;113(2):422-4. doi: 10.1046/j.1365-2141.2001.02765.x. PMID: 11380408

Recent systematic reviews

Evans C, Shepherd L, Bryan G, Fulbright H, Crowther S, Wakeling S, Stewart A, Stewart C, Chisholm J, Gibson F, Phillips B, Morgan JE
Int J Cancer 2024 Apr 1;154(7):1235-1260. Epub 2023 Dec 10 doi: 10.1002/ijc.34808. PMID: 38071594
Bladé J, Beksac M, Caers J, Jurczyszyn A, von Lilienfeld-Toal M, Moreau P, Rasche L, Rosiñol L, Usmani SZ, Zamagni E, Richardson P
Blood Cancer J 2022 Mar 21;12(3):45. doi: 10.1038/s41408-022-00643-3. PMID: 35314675Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...