GNAI Family Gene Mutation

MedGen UID:: 1645814
•Concept ID:: C4688378
•: Cell or Molecular Dysfunction

Synonyms:

G Protein Subunit Alpha I Gene Mutation; G(i) Alpha Gene Mutation; GNAI Gene Mutation; Guanine Nucleotide Binding Protein (G Protein), Alpha Inhibiting Activity Gene Mutation; Guanine Nucleotide Binding Protein Alpha Inhibiting Activity Gene Mutation; Guanine Nucleotide-Binding Protein G(i), Alpha Gene Mutation

Definition

A change in the nucleotide sequence of a GNAI family gene. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVGNAI Family Gene Mutation

Molecular Abnormality
- Molecular Sequence Variation
  - Molecular Genetic Variation
    - Gene Abnormality
      - GNAI Family Gene Mutation

Recent clinical studies

Diagnosis

Mutation analysis of inhibitory guanine nucleotide binding protein alpha (GNAI) loci in young and familial pituitary adenomas.

Demir H, Donner I, Kivipelto L, Kuismin O, Schalin-Jäntti C, De Menis E, Karhu A
PLoS One 2014;9(10):e109897. Epub 2014 Oct 7 doi: 10.1371/journal.pone.0109897. PMID: 25291362 Free PMC Article

See all (1)

Clinical prediction guides

Mutation analysis of inhibitory guanine nucleotide binding protein alpha (GNAI) loci in young and familial pituitary adenomas.

Demir H, Donner I, Kivipelto L, Kuismin O, Schalin-Jäntti C, De Menis E, Karhu A
PLoS One 2014;9(10):e109897. Epub 2014 Oct 7 doi: 10.1371/journal.pone.0109897. PMID: 25291362 Free PMC Article

Familial ACTH-independent Cushing's syndrome with bilateral macronodular adrenal hyperplasia clinically affecting only female family members.

Nies C, Bartsch DK, Ehlenz K, Wild A, Langer P, Fleischhacker S, Rothmund M
Exp Clin Endocrinol Diabetes 2002 Sep;110(6):277-83. doi: 10.1055/s-2002-34590. PMID: 12373631

See all (2)

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GNAI Family Gene Mutation

Definition

Term Hierarchy

Recent clinical studies

Diagnosis

Clinical prediction guides

Supplemental Content

Table of contents

Related information

Recent activity