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Refractory Waldenstrom Macroglobulinemia

MedGen UID:
1635976
Concept ID:
C4551756
Neoplastic Process

Definition

Waldenstrom macroglobulinemia that does not respond to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Waldenstrom Macroglobulinemia

Professional guidelines

PubMed

Amaador K, Kersten MJ, Minnema MC, Vos JMI
Leuk Lymphoma 2023 Jan;64(1):30-41. Epub 2022 Oct 25 doi: 10.1080/10428194.2022.2131423. PMID: 36282673

Recent clinical studies

Etiology

An G, Zhou D, Cheng S, Zhou K, Li J, Zhou J, Xie L, Jin J, Zhong L, Yan L, Guo H, Du C, Zhong J, Yu Y, Wu B, Qiu L
Clin Cancer Res 2021 Oct 15;27(20):5492-5501. Epub 2021 Jul 12 doi: 10.1158/1078-0432.CCR-21-0539. PMID: 34253577Free PMC Article
Owen RG, McCarthy H, Rule S, D'Sa S, Thomas SK, Tournilhac O, Forconi F, Kersten MJ, Zinzani PL, Iyengar S, Kothari J, Minnema MC, Kastritis E, Aurran-Schleinitz T, Cheson BD, Walter H, Greenwald D, Chen DY, Frigault MM, Hamdy A, Izumi R, Patel P, Wei H, Lee SK, Mittag D, Furman RR
Lancet Haematol 2020 Feb;7(2):e112-e121. Epub 2019 Dec 19 doi: 10.1016/S2352-3026(19)30210-8. PMID: 31866281
Ghobrial IM, Campigotto F, Murphy TJ, Boswell EN, Banwait R, Azab F, Chuma S, Kunsman J, Donovan A, Masood F, Warren D, Rodig S, Anderson KC, Richardson PG, Weller E, Matous J
Blood 2013 Feb 21;121(8):1296-303. Epub 2013 Jan 3 doi: 10.1182/blood-2012-06-439307. PMID: 23287861Free PMC Article
Ghobrial IM, Gertz M, Laplant B, Camoriano J, Hayman S, Lacy M, Chuma S, Harris B, Leduc R, Rourke M, Ansell SM, Deangelo D, Dispenzieri A, Bergsagel L, Reeder C, Anderson KC, Richardson PG, Treon SP, Witzig TE
J Clin Oncol 2010 Mar 10;28(8):1408-14. Epub 2010 Feb 8 doi: 10.1200/JCO.2009.24.0994. PMID: 20142598Free PMC Article

Therapy

Chohan KL, Kapoor P
Curr Hematol Malig Rep 2024 Aug;19(4):163-174. Epub 2024 Jul 6 doi: 10.1007/s11899-024-00730-1. PMID: 38970645
Amaador K, Kersten MJ, Minnema MC, Vos JMI
Leuk Lymphoma 2023 Jan;64(1):30-41. Epub 2022 Oct 25 doi: 10.1080/10428194.2022.2131423. PMID: 36282673
Trotman J, Buske C, Tedeschi A, Matous JV, MacDonald D, Tam CS, Tournilhac O, Ma S, Treon SP, Oriol A, Ping J, Briso EM, Arango-Hisijara I, Dimopoulos MA
Clin Cancer Res 2021 Nov 1;27(21):5793-5800. Epub 2021 Aug 11 doi: 10.1158/1078-0432.CCR-21-1497. PMID: 34380643Free PMC Article
An G, Zhou D, Cheng S, Zhou K, Li J, Zhou J, Xie L, Jin J, Zhong L, Yan L, Guo H, Du C, Zhong J, Yu Y, Wu B, Qiu L
Clin Cancer Res 2021 Oct 15;27(20):5492-5501. Epub 2021 Jul 12 doi: 10.1158/1078-0432.CCR-21-0539. PMID: 34253577Free PMC Article
Tomowiak C, Poulain S, Herbaux C, Perrot A, Mahé B, Morel P, Aurran T, Tournilhac O, Leprêtre S, Assaad S, Villemagne B, Casasnovas O, Nollet D, Roos-Weil D, Chevret S, Leblond V
Blood Adv 2021 May 11;5(9):2438-2446. doi: 10.1182/bloodadvances.2020003895. PMID: 33961019Free PMC Article

Prognosis

Chohan KL, Kapoor P
Curr Hematol Malig Rep 2024 Aug;19(4):163-174. Epub 2024 Jul 6 doi: 10.1007/s11899-024-00730-1. PMID: 38970645
Ghobrial IM, Campigotto F, Murphy TJ, Boswell EN, Banwait R, Azab F, Chuma S, Kunsman J, Donovan A, Masood F, Warren D, Rodig S, Anderson KC, Richardson PG, Weller E, Matous J
Blood 2013 Feb 21;121(8):1296-303. Epub 2013 Jan 3 doi: 10.1182/blood-2012-06-439307. PMID: 23287861Free PMC Article

Clinical prediction guides

Ghobrial IM, Redd R, Armand P, Banwait R, Boswell E, Chuma S, Huynh D, Sacco A, Roccaro AM, Perilla-Glen A, Noonan K, MacNabb M, Leblebjian H, Warren D, Henrick P, Castillo JJ, Richardson PG, Matous J, Weller E, Treon SP
Leukemia 2015 Dec;29(12):2338-46. Epub 2015 Jul 3 doi: 10.1038/leu.2015.164. PMID: 26139427
Ghobrial IM, Witzig TE, Gertz M, LaPlant B, Hayman S, Camoriano J, Lacy M, Bergsagel PL, Chuma S, DeAngelo D, Treon SP
Am J Hematol 2014 Mar;89(3):237-42. doi: 10.1002/ajh.23620. PMID: 24716234
Ghobrial IM, Gertz M, Laplant B, Camoriano J, Hayman S, Lacy M, Chuma S, Harris B, Leduc R, Rourke M, Ansell SM, Deangelo D, Dispenzieri A, Bergsagel L, Reeder C, Anderson KC, Richardson PG, Treon SP, Witzig TE
J Clin Oncol 2010 Mar 10;28(8):1408-14. Epub 2010 Feb 8 doi: 10.1200/JCO.2009.24.0994. PMID: 20142598Free PMC Article
Ghobrial IM, Hong F, Padmanabhan S, Badros A, Rourke M, Leduc R, Chuma S, Kunsman J, Warren D, Harris B, Sam A, Anderson KC, Richardson PG, Treon SP, Weller E, Matous J
J Clin Oncol 2010 Mar 10;28(8):1422-8. Epub 2010 Feb 8 doi: 10.1200/JCO.2009.25.3237. PMID: 20142586Free PMC Article

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