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Abnormal inferior oblique muscle physiology

MedGen UID:
1632780
•Concept ID:
C4703406
•
Disease or Syndrome
HPO: HP:0025596

Definition

A functional anomaly of the inferior oblique muscle, an extraocular muscle that has its origin on the maxillary bone just posterior to the inferior medial orbital rim and lateral to the nasolacrimal canal and that is innervated by the inferior branch of the oculomotor nerve. [from HPO]

Professional guidelines

PubMed

Phenotype, genotype, and management of congenital fibrosis of extraocular muscles type 1 in 16 Chinese families.
Chen M, Huang R, Zhang Y, Zhu DJ, Shu Q, Xun P, Zhang J, Gu P, Li L
Graefes Arch Clin Exp Ophthalmol 2023 Mar;261(3):879-889. Epub 2022 Sep 23 doi: 10.1007/s00417-022-05830-3. PMID: 36138147Free PMC Article
The diagnosis and treatment of infantile nystagmus syndrome (INS).
Khanna S, Dell'Osso LF
ScientificWorldJournal 2006 Oct 30;6:1385-97. doi: 10.1100/tsw.2006.248. PMID: 17086344Free PMC Article
Orbicular synkinesis after facial paralysis: treatment with botulinum toxin.
Roggenkämper P, Laskawi R, Damenz W, Schröder M, Nüssgens Z
Doc Ophthalmol 1994;86(4):395-402. doi: 10.1007/BF01204598. PMID: 7835177

Recent clinical studies

Etiology

Repair of the Malpositioned Lower Lid.
Chan D, Sokoya M, Ducic Y
Facial Plast Surg 2017 Dec;33(6):598-605. Epub 2017 Dec 1 doi: 10.1055/s-0037-1608711. PMID: 29195240
Congenital dystrophic medial rectus muscles.
Murthy R
Indian J Ophthalmol 2017 Jan;65(1):62-64. doi: 10.4103/ijo.IJO_537_15. PMID: 28300745Free PMC Article
Ocular choristomas.
Mansour AM, Barber JC, Reinecke RD, Wang FM
Surv Ophthalmol 1989 Mar-Apr;33(5):339-58. doi: 10.1016/0039-6257(89)90011-8. PMID: 2655139
Recurrent esotropia.
von Noorden GK, Munoz M, Raab EL
J Pediatr Ophthalmol Strabismus 1988 Nov-Dec;25(6):275-80; discussion 279-80. doi: 10.3928/0191-3913-19881101-06. PMID: 24880180
The diagnosis and treatment of bilateral masked superior oblique palsy.
Kushner BJ
Am J Ophthalmol 1988 Feb 15;105(2):186-94. doi: 10.1016/0002-9394(88)90184-5. PMID: 3277437

Diagnosis

Ophthalmoplegia and Congenital Cranial Dysinnervation Disorders.
Oystreck DT
J Binocul Vis Ocul Motil 2018 Jan-Mar;68(1):31-33. Epub 2018 Jan 31 doi: 10.1080/2576117X.2017.1416242. PMID: 30196776
Repair of the Malpositioned Lower Lid.
Chan D, Sokoya M, Ducic Y
Facial Plast Surg 2017 Dec;33(6):598-605. Epub 2017 Dec 1 doi: 10.1055/s-0037-1608711. PMID: 29195240
The congenital cranial dysinnervation disorders.
Gutowski NJ, Chilton JK
Arch Dis Child 2015 Jul;100(7):678-81. Epub 2015 Jan 29 doi: 10.1136/archdischild-2014-307035. PMID: 25633065
The anatomy and physiology of the ocular motor system.
Horn AK, Leigh RJ
Handb Clin Neurol 2011;102:21-69. doi: 10.1016/B978-0-444-52903-9.00008-X. PMID: 21601062
Duane's retraction syndrome.
Harmon DE, Primo SA
J Am Optom Assoc 1990 May;61(5):378-81. PMID: 2355166

Therapy

Occult thyroid eye disease in patients presenting with dry eye symptoms.
Gupta A, Sadeghi PB, Akpek EK
Am J Ophthalmol 2009 May;147(5):919-23. Epub 2009 Feb 10 doi: 10.1016/j.ajo.2008.12.007. PMID: 19211095
Diagnosing disconjugate eye movements: phase-plane analysis of horizontal saccades.
Serra A, Liao K, Matta M, Leigh RJ
Neurology 2008 Oct 7;71(15):1167-75. doi: 10.1212/01.wnl.0000327525.72168.57. PMID: 18838664Free PMC Article
Prefrontal and cerebellar abnormalities in major depression: evidence from oculomotor studies.
Sweeney JA, Strojwas MH, Mann JJ, Thase ME
Biol Psychiatry 1998 Apr 15;43(8):584-94. doi: 10.1016/s0006-3223(97)00485-x. PMID: 9564443
Surgical treatment of supranuclear and internuclear ocular motility disorders.
Buckley SA, Elston JS
Eye (Lond) 1997;11 ( Pt 3):377-80. doi: 10.1038/eye.1997.79. PMID: 9373480
A new variant of blepharospasm.
Elston JS
J Neurol Neurosurg Psychiatry 1992 May;55(5):369-71. doi: 10.1136/jnnp.55.5.369. PMID: 1602309Free PMC Article

Prognosis

Thyroid eye disease presenting with superior rectus/levator complex enlargement.
Wang Y, Mettu P, Broadbent T, Radke P, Firl K, Shepherd JB 3rd, Couch SM, Nguyen A, Henderson AD, McCulley T, McClelland CM, Mokhtarzadeh A, Lee MS, Garrity JA, Harrison AR
Orbit 2020 Feb;39(1):5-12. Epub 2019 May 6 doi: 10.1080/01676830.2019.1594969. PMID: 31056988
Long-term outcomes of strabismus surgery in Mobius sequence.
Lueder GT, Galli M
Strabismus 2019 Jun;27(2):43-46. Epub 2019 Apr 8 doi: 10.1080/09273972.2019.1599402. PMID: 30958093
Repair of the Malpositioned Lower Lid.
Chan D, Sokoya M, Ducic Y
Facial Plast Surg 2017 Dec;33(6):598-605. Epub 2017 Dec 1 doi: 10.1055/s-0037-1608711. PMID: 29195240
Strabismus in craniosynostosis.
Rosenberg JB, Tepper OM, Medow NB
J Pediatr Ophthalmol Strabismus 2013 May-Jun;50(3):140-8. Epub 2012 Nov 20 doi: 10.3928/01913913-20121113-02. PMID: 23163259
The anatomy and physiology of the ocular motor system.
Horn AK, Leigh RJ
Handb Clin Neurol 2011;102:21-69. doi: 10.1016/B978-0-444-52903-9.00008-X. PMID: 21601062

Clinical prediction guides

Extraocular muscle hypoplasia associated with Axenfeld-Rieger syndrome.
De Decker M, Cassiman C, Casteels I, Devriendt K, Delbeke P
Strabismus 2021 Dec;29(4):216-220. Epub 2021 Oct 28 doi: 10.1080/09273972.2021.1987926. PMID: 34709103
Disrupted neural signals in patients with concomitant exotropia.
Xi S, Yao J, Zhang S, Liu R, Wu L, Ye X, Zhang P, Wen W, Zhao C
Ophthalmic Physiol Opt 2020 Sep;40(5):650-659. Epub 2020 Jul 16 doi: 10.1111/opo.12715. PMID: 32672862
Congenital Cranial Dysinnervation Disorders: A Literature Review.
Fels R
Am Orthopt J 2017 Jan;67(1):89-92. doi: 10.3368/aoj.67.1.89. PMID: 28904220
The anatomy and physiology of the ocular motor system.
Horn AK, Leigh RJ
Handb Clin Neurol 2011;102:21-69. doi: 10.1016/B978-0-444-52903-9.00008-X. PMID: 21601062
Isolated third nerve palsies.
Trobe JD
Semin Neurol 1986 Jun;6(2):135-41. doi: 10.1055/s-2008-1041456. PMID: 3332417

Recent systematic reviews

Oculomotor functions in focal dystonias: A systematic review.
Hirsig A, Barbey C, Schüpbach MWM, Bargiotas P
Acta Neurol Scand 2020 May;141(5):359-367. Epub 2020 Feb 12 doi: 10.1111/ane.13224. PMID: 31990980
Clinical and histologic ocular findings in pompe disease.
Yanovitch TL, Banugaria SG, Proia AD, Kishnani PS
J Pediatr Ophthalmol Strabismus 2010 Jan-Feb;47(1):34-40. Epub 2010 Jan 21 doi: 10.3928/01913913-20100106-08. PMID: 20128552

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