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Recurrent Lung Squamous Cell Carcinoma

MedGen UID:
163175
•Concept ID:
C0854989
•
Neoplastic Process
Synonyms: Recurrent Squamous Cell Carcinoma of Lung; Recurrent Squamous Cell Carcinoma of the Lung; Recurrent Squamous Cell Lung Carcinoma

Definition

The re-emergence of squamous cell lung carcinoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Lung Squamous Cell Carcinoma

Professional guidelines

PubMed

Recent Advances in the Management of Small Cell Carcinoma of the Uterine Cervix.
Miyoshi AI, Ueda Y, Kurita T, Kimura T, Yoshino K
Anticancer Res 2023 Apr;43(4):1397-1405. doi: 10.21873/anticanres.16288. PMID: 36974776
Systemic Bevacizumab Treatment for Recurrent Respiratory Papillomatosis: Long-Term Follow-Up.
Ruiz R, Balamuth N, Javia LR, Zur KB
Laryngoscope 2022 Oct;132(10):2071-2075. Epub 2022 Jan 19 doi: 10.1002/lary.30021. PMID: 35043981
Surgical Management of Oral Cancer.
Shanti RM, O'Malley BW Jr
Dent Clin North Am 2018 Jan;62(1):77-86. Epub 2017 Oct 16 doi: 10.1016/j.cden.2017.08.005. PMID: 29126495

Recent clinical studies

Etiology

Necitumumab plus gemcitabine and cisplatin in previously treated lung squamous cell carcinoma.
Kinoshita F, Oku Y, Takamori S, Fujishita T, Toyozawa R, Ito K, Shoji F, Okamoto T
Invest New Drugs 2023 Feb;41(1):168-172. Epub 2022 Nov 4 doi: 10.1007/s10637-022-01312-9. PMID: 36331673
Segmentectomy for clinically early-stage primary squamous cell carcinoma of the lung.
Kagimoto A, Tsutani Y, Shimada Y, Mimae T, Miyata Y, Ito H, Nakayama H, Ikeda N, Okada M
Thorac Cancer 2022 Dec;13(24):3477-3485. Epub 2022 Nov 8 doi: 10.1111/1759-7714.14707. PMID: 36346136Free PMC Article
Skin Cancers and Lung Transplant.
Wilken R, Carucci J, Stevenson ML
Semin Respir Crit Care Med 2021 Jun;42(3):483-496. Epub 2021 May 24 doi: 10.1055/s-0041-1728798. PMID: 34030209
Cell adhesion and polarity in squamous cell carcinoma of the lung.
Bonastre E, Brambilla E, Sanchez-Cespedes M
J Pathol 2016 Apr;238(5):606-16. Epub 2016 Feb 29 doi: 10.1002/path.4686. PMID: 26749265
Lung-MAP--framework, overview, and design principles.
Ferrarotto R, Redman MW, Gandara DR, Herbst RS, Papadimitrakopoulou VA
Chin Clin Oncol 2015 Sep;4(3):36. doi: 10.3978/j.issn.2304-3865.2015.09.02. PMID: 26408303

Diagnosis

Oropharyngeal squamous cell carcinoma: Prognostic factors for development of distant metastases and oncological outcomes.
Mattioli F, Lo Manto A, Miglio M, Serafini E, Rossi D, Valerini S, Tonelli R, Fermi M, Pugliese G, Bertolini F, D'Angelo E, Depenni R, Dominici M, Lohr FRH, Marchioni D
Head Neck 2023 Jun;45(6):1406-1417. Epub 2023 Apr 11 doi: 10.1002/hed.27354. PMID: 37040549
Necitumumab plus gemcitabine and cisplatin in previously treated lung squamous cell carcinoma.
Kinoshita F, Oku Y, Takamori S, Fujishita T, Toyozawa R, Ito K, Shoji F, Okamoto T
Invest New Drugs 2023 Feb;41(1):168-172. Epub 2022 Nov 4 doi: 10.1007/s10637-022-01312-9. PMID: 36331673
Biomarker-driven therapies for previously treated squamous non-small-cell lung cancer (Lung-MAP SWOG S1400): a biomarker-driven master protocol.
Redman MW, Papadimitrakopoulou VA, Minichiello K, Hirsch FR, Mack PC, Schwartz LH, Vokes E, Ramalingam S, Leighl N, Bradley J, Miao J, Moon J, Highleyman L, Miwa C, LeBlanc ML, Malik S, Miller VA, Sigal EV, Adam S, Wholley D, Sigman C, Smolich B, Blanke CD, Kelly K, Gandara DR, Herbst RS
Lancet Oncol 2020 Dec;21(12):1589-1601. Epub 2020 Oct 27 doi: 10.1016/S1470-2045(20)30475-7. PMID: 33125909Free PMC Article
Recurrent respiratory papillomatosis: A state-of-the-art review.
Fortes HR, von Ranke FM, Escuissato DL, Araujo Neto CA, Zanetti G, Hochhegger B, Souza CA, Marchiori E
Respir Med 2017 May;126:116-121. Epub 2017 Apr 1 doi: 10.1016/j.rmed.2017.03.030. PMID: 28427542
Lung-MAP--framework, overview, and design principles.
Ferrarotto R, Redman MW, Gandara DR, Herbst RS, Papadimitrakopoulou VA
Chin Clin Oncol 2015 Sep;4(3):36. doi: 10.3978/j.issn.2304-3865.2015.09.02. PMID: 26408303

Therapy

Nivolumab plus chemotherapy in first-line metastatic non-small-cell lung cancer: results of the phase III CheckMate 227 Part 2 trial.
Borghaei H, O'Byrne KJ, Paz-Ares L, Ciuleanu TE, Yu X, Pluzanski A, Nagrial A, Havel L, Kowalyszyn RD, Valette CA, Brahmer JR, Reck M, Ramalingam SS, Zhang L, Ntambwe I, Rabindran SK, Nathan FE, Balli D, Wu YL
ESMO Open 2023 Dec;8(6):102065. Epub 2023 Nov 20 doi: 10.1016/j.esmoop.2023.102065. PMID: 37988950Free PMC Article
A Phase II Study of Telisotuzumab Vedotin in Patients With c-MET-positive Stage IV or Recurrent Squamous Cell Lung Cancer (LUNG-MAP Sub-study S1400K, NCT03574753).
Waqar SN, Redman MW, Arnold SM, Hirsch FR, Mack PC, Schwartz LH, Gandara DR, Stinchcombe TE, Leighl NB, Ramalingam SS, Tanna SH, Raddin RS, Minichiello K, Bradley JD, Kelly K, Herbst RS, Papadimitrakopoulou VA
Clin Lung Cancer 2021 May;22(3):170-177. Epub 2020 Oct 14 doi: 10.1016/j.cllc.2020.09.013. PMID: 33221175Free PMC Article
Biomarker-driven therapies for previously treated squamous non-small-cell lung cancer (Lung-MAP SWOG S1400): a biomarker-driven master protocol.
Redman MW, Papadimitrakopoulou VA, Minichiello K, Hirsch FR, Mack PC, Schwartz LH, Vokes E, Ramalingam S, Leighl N, Bradley J, Miao J, Moon J, Highleyman L, Miwa C, LeBlanc ML, Malik S, Miller VA, Sigal EV, Adam S, Wholley D, Sigman C, Smolich B, Blanke CD, Kelly K, Gandara DR, Herbst RS
Lancet Oncol 2020 Dec;21(12):1589-1601. Epub 2020 Oct 27 doi: 10.1016/S1470-2045(20)30475-7. PMID: 33125909Free PMC Article
Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations.
Chang J, Tan W, Ling Z, Xi R, Shao M, Chen M, Luo Y, Zhao Y, Liu Y, Huang X, Xia Y, Hu J, Parker JS, Marron D, Cui Q, Peng L, Chu J, Li H, Du Z, Han Y, Tan W, Liu Z, Zhan Q, Li Y, Mao W, Wu C, Lin D
Nat Commun 2017 May 26;8:15290. doi: 10.1038/ncomms15290. PMID: 28548104Free PMC Article
Teflon haemoptysis.
Aboudara M, Krimsky W, Harley D
BMJ Case Rep 2012 Mar 20;2012 doi: 10.1136/bcr.12.2011.5279. PMID: 22605709Free PMC Article

Prognosis

Segmentectomy for clinically early-stage primary squamous cell carcinoma of the lung.
Kagimoto A, Tsutani Y, Shimada Y, Mimae T, Miyata Y, Ito H, Nakayama H, Ikeda N, Okada M
Thorac Cancer 2022 Dec;13(24):3477-3485. Epub 2022 Nov 8 doi: 10.1111/1759-7714.14707. PMID: 36346136Free PMC Article
Therapy-Related Transcriptional Subtypes in Matched Primary and Recurrent Head and Neck Cancer.
Weber P, Künstner A, Hess J, Unger K, Marschner S, Idel C, Ribbat-Idel J, Baumeister P, Gires O, Walz C, Rietzler S, Valeanu L, Herkommer T, Kreutzer L, Klymenko O, Drexler G, Kirchner T, Maihöfer C, Ganswindt U, Walch A, Sterr M, Lickert H, Canis M, Rades D, Perner S, Berriel Diaz M, Herzig S, Lauber K, Wollenberg B, Busch H, Belka C, Zitzelsberger H
Clin Cancer Res 2022 Mar 1;28(5):1038-1052. doi: 10.1158/1078-0432.CCR-21-2244. PMID: 34965946
Deregulation of AKT-mTOR Signaling Contributes to Chemoradiation Resistance in Lung Squamous Cell Carcinoma.
Shen C, Shyu DL, Xu M, Yang L, Webb A, Duan W, Williams TM
Mol Cancer Res 2022 Mar 1;20(3):425-433. doi: 10.1158/1541-7786.MCR-21-0272. PMID: 34810212Free PMC Article
Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas.
Campbell JD, Alexandrov A, Kim J, Wala J, Berger AH, Pedamallu CS, Shukla SA, Guo G, Brooks AN, Murray BA, Imielinski M, Hu X, Ling S, Akbani R, Rosenberg M, Cibulskis C, Ramachandran A, Collisson EA, Kwiatkowski DJ, Lawrence MS, Weinstein JN, Verhaak RG, Wu CJ, Hammerman PS, Cherniack AD, Getz G; Cancer Genome Atlas Research Network, Artyomov MN, Schreiber R, Govindan R, Meyerson M
Nat Genet 2016 Jun;48(6):607-16. Epub 2016 May 9 doi: 10.1038/ng.3564. PMID: 27158780Free PMC Article
Clinicopathologic features of peripheral squamous cell carcinoma of the lung.
Sakurai H, Asamura H, Watanabe S, Suzuki K, Tsuchiya R
Ann Thorac Surg 2004 Jul;78(1):222-7. doi: 10.1016/j.athoracsur.2004.01.029. PMID: 15223433

Clinical prediction guides

Nivolumab plus chemotherapy in first-line metastatic non-small-cell lung cancer: results of the phase III CheckMate 227 Part 2 trial.
Borghaei H, O'Byrne KJ, Paz-Ares L, Ciuleanu TE, Yu X, Pluzanski A, Nagrial A, Havel L, Kowalyszyn RD, Valette CA, Brahmer JR, Reck M, Ramalingam SS, Zhang L, Ntambwe I, Rabindran SK, Nathan FE, Balli D, Wu YL
ESMO Open 2023 Dec;8(6):102065. Epub 2023 Nov 20 doi: 10.1016/j.esmoop.2023.102065. PMID: 37988950Free PMC Article
SAMD9 Promotes Postoperative Recurrence of Esophageal Squamous Cell Carcinoma by Stimulating MYH9-Mediated GSK3β/β-Catenin Signaling.
Li Q, Luo H, Dai FQ, Wang RT, Fan XQ, Luo YY, Deng MS, Wang Y, Long T, Guo W, Xu B, Xu CX, Jin H
Adv Sci (Weinh) 2023 Apr;10(11):e2203573. Epub 2023 Feb 9 doi: 10.1002/advs.202203573. PMID: 36757050Free PMC Article
A Phase II Study of Telisotuzumab Vedotin in Patients With c-MET-positive Stage IV or Recurrent Squamous Cell Lung Cancer (LUNG-MAP Sub-study S1400K, NCT03574753).
Waqar SN, Redman MW, Arnold SM, Hirsch FR, Mack PC, Schwartz LH, Gandara DR, Stinchcombe TE, Leighl NB, Ramalingam SS, Tanna SH, Raddin RS, Minichiello K, Bradley JD, Kelly K, Herbst RS, Papadimitrakopoulou VA
Clin Lung Cancer 2021 May;22(3):170-177. Epub 2020 Oct 14 doi: 10.1016/j.cllc.2020.09.013. PMID: 33221175Free PMC Article
Biomarker-driven therapies for previously treated squamous non-small-cell lung cancer (Lung-MAP SWOG S1400): a biomarker-driven master protocol.
Redman MW, Papadimitrakopoulou VA, Minichiello K, Hirsch FR, Mack PC, Schwartz LH, Vokes E, Ramalingam S, Leighl N, Bradley J, Miao J, Moon J, Highleyman L, Miwa C, LeBlanc ML, Malik S, Miller VA, Sigal EV, Adam S, Wholley D, Sigman C, Smolich B, Blanke CD, Kelly K, Gandara DR, Herbst RS
Lancet Oncol 2020 Dec;21(12):1589-1601. Epub 2020 Oct 27 doi: 10.1016/S1470-2045(20)30475-7. PMID: 33125909Free PMC Article
Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas.
Campbell JD, Alexandrov A, Kim J, Wala J, Berger AH, Pedamallu CS, Shukla SA, Guo G, Brooks AN, Murray BA, Imielinski M, Hu X, Ling S, Akbani R, Rosenberg M, Cibulskis C, Ramachandran A, Collisson EA, Kwiatkowski DJ, Lawrence MS, Weinstein JN, Verhaak RG, Wu CJ, Hammerman PS, Cherniack AD, Getz G; Cancer Genome Atlas Research Network, Artyomov MN, Schreiber R, Govindan R, Meyerson M
Nat Genet 2016 Jun;48(6):607-16. Epub 2016 May 9 doi: 10.1038/ng.3564. PMID: 27158780Free PMC Article

Recent systematic reviews

A systematic review of antibody-drug conjugates and bispecific antibodies in head and neck squamous cell carcinoma and nasopharyngeal carcinoma: Charting the course of future therapies.
Jiménez-Labaig P, Rullan A, Hernando-Calvo A, Llop S, Bhide S, O'Leary B, Braña I, Harrington KJ
Cancer Treat Rev 2024 Jul;128:102772. Epub 2024 May 26 doi: 10.1016/j.ctrv.2024.102772. PMID: 38820656
Intratumoral therapies in head and neck squamous cell carcinoma: A systematic review and future perspectives.
Jiménez-Labaig P, Rullan A, Braña I, Hernando-Calvo A, Moreno V, Doger B, Bitar G, Ap Dafydd D, Melcher A, Harrington KJ
Cancer Treat Rev 2024 Jun;127:102746. Epub 2024 Apr 27 doi: 10.1016/j.ctrv.2024.102746. PMID: 38696902
The Diagnostic and Prognostic Value of miR-155 in Cancers: An Updated Meta-analysis.
Wu Y, Hong Q, Lu F, Zhang Z, Li J, Nie Z, He B
Mol Diagn Ther 2023 May;27(3):283-301. Epub 2023 Mar 20 doi: 10.1007/s40291-023-00641-6. PMID: 36939982
Primary intraosseous squamous cell carcinoma arising from an odontogenic keratocyst: case series and literature review.
Ye P, Wei T, Gao Y, Zhang W, Peng X
Med Oral Patol Oral Cir Bucal 2021 Jan 1;26(1):e49-e55. doi: 10.4317/medoral.23947. PMID: 33037806Free PMC Article
Current studies of immunotherapy in head and neck cancer.
Dogan V, Rieckmann T, Münscher A, Busch CJ
Clin Otolaryngol 2018 Feb;43(1):13-21. Epub 2017 May 29 doi: 10.1111/coa.12895. PMID: 28464441

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