U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Hemiparkinsonism-hemiatrophy syndrome

MedGen UID:
1627807
Concept ID:
C4545231
Disease or Syndrome
Synonyms: Hemiparkinsonism hemiatrophy syndrome; hemiparkinsonism-hemiatrophy syndrome; HP-HA syndrome; Hp-HA syndrome
SNOMED CT: Hemiparkinsonism hemiatrophy syndrome (737582007)
 
Monarch Initiative: MONDO:0017636
Orphanet: ORPHA306669

Definition

A rare parkinsonian disorder with characteristics of unilateral body atrophy and slowly progressive, ipsilateral hemiparkinsonian signs (bradykinesia, rigidity, and tremor). Patients typically present with unilateral, action-induced dystonia, in upper or lower limbs, that progresses and becomes bilateral or with tremor which occurs predominantly at rest and progresses to hemiparkinsonism. Scoliosis, scapular winging, raised shoulders, brisk reflexes and extensor plantars are frequently associated. [from SNOMEDCT_US]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Hemiparkinsonism-hemiatrophy syndrome

Recent clinical studies

Etiology

Wijemanne S, Jankovic J
Mov Disord 2009 Mar 15;24(4):583-9. doi: 10.1002/mds.22415. PMID: 19097182
Giladi N, Burke RE, Kostic V, Przedborski S, Gordon M, Hunt A, Fahn S
Neurology 1990 Nov;40(11):1731-4. doi: 10.1212/wnl.40.11.1731. PMID: 2234429

Diagnosis

Chung SJ
BMC Neurol 2021 Feb 3;21(1):51. doi: 10.1186/s12883-021-02080-4. PMID: 33535984Free PMC Article
Dziadkiewicz A, Białecka M, Janik P, Sławek J
Neurol Neurochir Pol 2013 Jul-Aug;47(4):387-92. doi: 10.5114/ninp.2013.34557. PMID: 23986429
Ayromlou H, Najmi S, Arami MA
Arch Iran Med 2011 Mar;14(2):152-4. PMID: 21361726
Wijemanne S, Jankovic J
Neurology 2007 Oct 16;69(16):1585-94. doi: 10.1212/01.wnl.0000277699.48155.39. PMID: 17938368
Giladi N, Burke RE, Kostic V, Przedborski S, Gordon M, Hunt A, Fahn S
Neurology 1990 Nov;40(11):1731-4. doi: 10.1212/wnl.40.11.1731. PMID: 2234429

Therapy

Chung SJ
BMC Neurol 2021 Feb 3;21(1):51. doi: 10.1186/s12883-021-02080-4. PMID: 33535984Free PMC Article
Ayromlou H, Najmi S, Arami MA
Arch Iran Med 2011 Mar;14(2):152-4. PMID: 21361726
Lang AE
Mov Disord 1995 Jul;10(4):489-95. doi: 10.1002/mds.870100414. PMID: 7565831
Costa B, Zanette G, Bertolasi L, Fiaschi A
Eur Neurol 1994;34(2):107-9. doi: 10.1159/000117019. PMID: 8174592
Giladi N, Burke RE, Kostic V, Przedborski S, Gordon M, Hunt A, Fahn S
Neurology 1990 Nov;40(11):1731-4. doi: 10.1212/wnl.40.11.1731. PMID: 2234429

Prognosis

Wijemanne S, Jankovic J
Neurology 2007 Oct 16;69(16):1585-94. doi: 10.1212/01.wnl.0000277699.48155.39. PMID: 17938368
Przedborski S, Goldman S, Levivier M, Giladi N, Bidaut LM, Hildebrand J, Stanus E, Labar D, Luxen A
Mov Disord 1993 Jul;8(3):391-5. doi: 10.1002/mds.870080329. PMID: 8341311
Giladi N, Burke RE, Kostic V, Przedborski S, Gordon M, Hunt A, Fahn S
Neurology 1990 Nov;40(11):1731-4. doi: 10.1212/wnl.40.11.1731. PMID: 2234429

Clinical prediction guides

Giladi N, Burke RE, Kostic V, Przedborski S, Gordon M, Hunt A, Fahn S
Neurology 1990 Nov;40(11):1731-4. doi: 10.1212/wnl.40.11.1731. PMID: 2234429

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...