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Refractory Langerhans Cell Histiocytosis

MedGen UID:
1615706
Concept ID:
C4525081
Neoplastic Process

Definition

Langerhans cell histiocytosis that does not respond to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Langerhans Cell Histiocytosis

Professional guidelines

PubMed

Diamond A
Br J Haematol 2024 May;204(5):1588-1589. Epub 2024 Apr 12 doi: 10.1111/bjh.19473. PMID: 38606542
Apollonsky N, Lipton JM
J Pediatr Hematol Oncol 2009 Jan;31(1):53-6. doi: 10.1097/MPH.0b013e31817e4a32. PMID: 19125089

Recent clinical studies

Therapy

Karri V, Lin H, Velazquez J, Batajoo A, Parekh D, Stanton W, Abhyankar H, El-Mallawany NK, Agrusa J, Eckstein O, Gulati N, Schwartz J, Woods-Swafford W, Boyd J, Saha A, Allen CE, McClain KL
Br J Haematol 2024 May;204(5):1882-1887. Epub 2024 Mar 19 doi: 10.1111/bjh.19380. PMID: 38501390
Parekh D, Lin H, Batajoo A, Peckham-Gregory E, Karri V, Stanton W, Scull B, Fleishmann R, El-Mallawany N, Eckstein OS, Prudowsky ZD, Gulati N, Agrusa JE, Ahmed AZ, Chu R, Dietz MS, Goldman SC, Hogarty MD, Imran H, Intzes S, Kim JM, Kopp LM, Levy CF, Neff P, Pillai PM, Sisk BA, Schiff DE, Trobaugh-Lotrario AD, Walkovich K, McClain KL, Allen CE
Br J Haematol 2024 May;204(5):1888-1893. Epub 2024 Mar 19 doi: 10.1111/bjh.19376. PMID: 38501389
Irie M, Nakano T, Katayama S, Suzuki T, Moriya K, Watanabe Y, Suzuki N, Saitoh-Nanjyo Y, Onuma M, Rikiishi T, Niizuma H, Sasahara Y, Kure S
Cancer Rep (Hoboken) 2022 Aug;5(8):e1579. Epub 2021 Nov 1 doi: 10.1002/cnr2.1579. PMID: 34725963Free PMC Article
Özyörük D, Yozgat AK, Kaçar D, Yazal Erdem A, Işık M, Güzelküçük Z, Hacısalihoğlu Ş
Tumori 2021 Dec;107(6):NP120-NP122. Epub 2021 Aug 21 doi: 10.1177/03008916211039555. PMID: 34423687
Veys PA, Nanduri V, Baker KS, He W, Bandini G, Biondi A, Dalissier A, Davis JH, Eames GM, Egeler RM, Filipovich AH, Fischer A, Jürgens H, Krance R, Lanino E, Leung WH, Matthes S, Michel G, Orchard PJ, Pieczonka A, Ringdén O, Schlegel PG, Sirvent A, Vettenranta K, Eapen M
Br J Haematol 2015 Jun;169(5):711-8. Epub 2015 Mar 27 doi: 10.1111/bjh.13347. PMID: 25817915Free PMC Article

Prognosis

Monsereenusorn C, Suwannaying K, Buaboonnam J, Sathitsamitphong L, Techavichit P, Pakakasama S, Chainansamit SO, Anurathapan U, Komvilaisak P, Traivaree C, Sanpakit K, Charoenkwan P, Seksarn P
Asian Pac J Cancer Prev 2024 May 1;25(5):1831-1839. doi: 10.31557/APJCP.2024.25.5.1831. PMID: 38809656Free PMC Article
Irie M, Nakano T, Katayama S, Suzuki T, Moriya K, Watanabe Y, Suzuki N, Saitoh-Nanjyo Y, Onuma M, Rikiishi T, Niizuma H, Sasahara Y, Kure S
Cancer Rep (Hoboken) 2022 Aug;5(8):e1579. Epub 2021 Nov 1 doi: 10.1002/cnr2.1579. PMID: 34725963Free PMC Article
Özyörük D, Yozgat AK, Kaçar D, Yazal Erdem A, Işık M, Güzelküçük Z, Hacısalihoğlu Ş
Tumori 2021 Dec;107(6):NP120-NP122. Epub 2021 Aug 21 doi: 10.1177/03008916211039555. PMID: 34423687
Kudo K, Maeda M, Suzuki N, Kanegane H, Ohga S, Ishii E, Shioda Y, Imamura T, Imashuku S, Tsunematsu Y, Endo M, Shimada A, Koga Y, Hashii Y, Noguchi M, Inoue M, Tabuchi K, Morimoto A; Histiocytosis study group of the Japanese Society of Pediatric Hematology/Oncology
Int J Hematol 2020 Jan;111(1):137-148. Epub 2019 Nov 22 doi: 10.1007/s12185-019-02760-5. PMID: 31758416
Cooper N, Rao K, Goulden N, Webb D, Amrolia P, Veys P
Bone Marrow Transplant 2008 Oct;42 Suppl 2:S47-50. doi: 10.1038/bmt.2008.283. PMID: 18978744

Clinical prediction guides

Monsereenusorn C, Suwannaying K, Buaboonnam J, Sathitsamitphong L, Techavichit P, Pakakasama S, Chainansamit SO, Anurathapan U, Komvilaisak P, Traivaree C, Sanpakit K, Charoenkwan P, Seksarn P
Asian Pac J Cancer Prev 2024 May 1;25(5):1831-1839. doi: 10.31557/APJCP.2024.25.5.1831. PMID: 38809656Free PMC Article
Ocak S, Bayramoglu Z, Tugcu D, Karaman S, Unuvar A, Karakas Z
J Pediatr Hematol Oncol 2021 Apr 1;43(3):e375-e379. doi: 10.1097/MPH.0000000000001770. PMID: 32097280
Hao X, Feng R, Bi Y, Liu Y, Li C, Lu T, Tian Y
J Neurosurg Pediatr 2019 Jan 1;23(1):48-53. Epub 2018 Sep 28 doi: 10.3171/2018.6.PEDS17728. PMID: 30265230
Akkari V, Donadieu J, Piguet C, Bordigoni P, Michel G, Blanche S, Casanova JL, Thomas C, Vilmer E, Fischer A, Bertrand Y; French Langerhans Cell Study Group
Bone Marrow Transplant 2003 Jun;31(12):1097-103. doi: 10.1038/sj.bmt.1704065. PMID: 12796789
Aricò M, Colella R, Conter V, Indolfi P, Pession A, Santoro N, Burgio GR
Med Pediatr Oncol 1995 Jul;25(1):12-6. doi: 10.1002/mpo.2950250104. PMID: 7752996

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    Practice guidelines

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