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Refractory Neuroblastoma

MedGen UID:
1613939
Concept ID:
C4525059
Neoplastic Process

Definition

A neuroblastoma that does not respond to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Neuroblastoma

Professional guidelines

PubMed

Chou SW, Chang HH
Cancer Lett 2024 Apr 28;588:216617. Epub 2024 Feb 2 doi: 10.1016/j.canlet.2024.216617. PMID: 38311055
Greenwood KL, Foster JH
Expert Opin Drug Saf 2018 Dec;17(12):1257-1262. Epub 2018 Nov 28 doi: 10.1080/14740338.2018.1549221. PMID: 30433831
Suzuki M, Kushner BH, Kramer K, Basu EM, Roberts SS, Hammond WJ, LaQuaglia MP, Wolden SL, Cheung NV, Modak S
Int J Cancer 2018 Sep 1;143(5):1249-1258. Epub 2018 Apr 6 doi: 10.1002/ijc.31399. PMID: 29574715Free PMC Article

Recent clinical studies

Etiology

Kobushi H, Saida S, Umeda K, Iwai A, Kozuki K, Kubota H, Tanaka K, Obu S, Uchihara Y, Tasaka K, Kato I, Hiramatsu H, Takita J
Pediatr Blood Cancer 2023 Jul;70(7):e30331. Epub 2023 Apr 17 doi: 10.1002/pbc.30331. PMID: 37066594
Sato T, Hara K, Ohba G, Yamamoto H, Iguchi A
Pediatr Int 2021 Jul;63(7):849-851. Epub 2021 Apr 27 doi: 10.1111/ped.14489. PMID: 33904642
Mody R, Yu AL, Naranjo A, Zhang FF, London WB, Shulkin BL, Parisi MT, Servaes SE, Diccianni MB, Hank JA, Felder M, Birstler J, Sondel PM, Asgharzadeh S, Glade-Bender J, Katzenstein H, Maris JM, Park JR, Bagatell R
J Clin Oncol 2020 Jul 1;38(19):2160-2169. Epub 2020 Apr 28 doi: 10.1200/JCO.20.00203. PMID: 32343642Free PMC Article
Steineck A, MacKenzie JD, Twist CJ
Pediatr Blood Cancer 2016 Nov;63(11):2050-3. Epub 2016 Jul 11 doi: 10.1002/pbc.26124. PMID: 27399265
DuBois SG, Matthay KK
Q J Nucl Med Mol Imaging 2013 Mar;57(1):53-65. PMID: 23474635

Diagnosis

O'Donohue TJ, Ibáñez G, Coutinho DF, Mauguen A, Siddiquee A, Rosales N, Calder P, Ndengu A, You D, Long M, Roberts SS, Kung AL, Dela Cruz FS
Mol Cancer Ther 2021 Nov;20(11):2189-2197. Epub 2021 Sep 4 doi: 10.1158/1535-7163.MCT-21-0126. PMID: 34482287Free PMC Article
Sato T, Hara K, Ohba G, Yamamoto H, Iguchi A
Pediatr Int 2021 Jul;63(7):849-851. Epub 2021 Apr 27 doi: 10.1111/ped.14489. PMID: 33904642
Suzuki M, Kushner BH, Kramer K, Basu EM, Roberts SS, Hammond WJ, LaQuaglia MP, Wolden SL, Cheung NV, Modak S
Int J Cancer 2018 Sep 1;143(5):1249-1258. Epub 2018 Apr 6 doi: 10.1002/ijc.31399. PMID: 29574715Free PMC Article
Mody R, Naranjo A, Van Ryn C, Yu AL, London WB, Shulkin BL, Parisi MT, Servaes SE, Diccianni MB, Sondel PM, Bender JG, Maris JM, Park JR, Bagatell R
Lancet Oncol 2017 Jul;18(7):946-957. Epub 2017 May 23 doi: 10.1016/S1470-2045(17)30355-8. PMID: 28549783Free PMC Article
DuBois SG, Matthay KK
Q J Nucl Med Mol Imaging 2013 Mar;57(1):53-65. PMID: 23474635

Therapy

Heczey A, Xu X, Courtney AN, Tian G, Barragan GA, Guo L, Amador CM, Ghatwai N, Rathi P, Wood MS, Li Y, Zhang C, Demberg T, Di Pierro EJ, Sher AC, Zhang H, Mehta B, Thakkar SG, Grilley B, Wang T, Weiss BD, Montalbano A, Subramaniam M, Xu C, Sachar C, Wells DK, Dotti G, Metelitsa LS
Nat Med 2023 Jun;29(6):1379-1388. Epub 2023 May 15 doi: 10.1038/s41591-023-02363-y. PMID: 37188782
Heczey A, Courtney AN, Montalbano A, Robinson S, Liu K, Li M, Ghatwai N, Dakhova O, Liu B, Raveh-Sadka T, Chauvin-Fleurence CN, Xu X, Ngai H, Di Pierro EJ, Savoldo B, Dotti G, Metelitsa LS
Nat Med 2020 Nov;26(11):1686-1690. Epub 2020 Oct 12 doi: 10.1038/s41591-020-1074-2. PMID: 33046868
Mody R, Yu AL, Naranjo A, Zhang FF, London WB, Shulkin BL, Parisi MT, Servaes SE, Diccianni MB, Hank JA, Felder M, Birstler J, Sondel PM, Asgharzadeh S, Glade-Bender J, Katzenstein H, Maris JM, Park JR, Bagatell R
J Clin Oncol 2020 Jul 1;38(19):2160-2169. Epub 2020 Apr 28 doi: 10.1200/JCO.20.00203. PMID: 32343642Free PMC Article
Mody R, Naranjo A, Van Ryn C, Yu AL, London WB, Shulkin BL, Parisi MT, Servaes SE, Diccianni MB, Sondel PM, Bender JG, Maris JM, Park JR, Bagatell R
Lancet Oncol 2017 Jul;18(7):946-957. Epub 2017 May 23 doi: 10.1016/S1470-2045(17)30355-8. PMID: 28549783Free PMC Article
DuBois SG, Matthay KK
Q J Nucl Med Mol Imaging 2013 Mar;57(1):53-65. PMID: 23474635

Prognosis

Moreno L, Weston R, Owens C, Valteau-Couanet D, Gambart M, Castel V, Zwaan CM, Nysom K, Gerber N, Castellano A, Laureys G, Ladenstein R, Rössler J, Makin G, Murphy D, Morland B, Vaidya S, Thebaud E, van Eijkelenburg N, Tweddle DA, Barone G, Tandonnet J, Corradini N, Chastagner P, Paillard C, Bautista FJ, Gallego Melcon S, De Wilde B, Marshall L, Gray J, Burchill SA, Schleiermacher G, Chesler L, Peet A, Leach MO, McHugh K, Hayes R, Jerome N, Caron H, Laidler J, Fenwick N, Holt G, Moroz V, Kearns P, Gates S, Pearson ADJ, Wheatley K; Innovative Therapies for Children with Cancer (ITCC) and European Association for Neuroblastoma Research (SIOPEN)
J Clin Oncol 2024 Apr 1;42(10):1135-1145. Epub 2024 Jan 8 doi: 10.1200/JCO.23.00458. PMID: 38190578
Mody R, Yu AL, Naranjo A, Zhang FF, London WB, Shulkin BL, Parisi MT, Servaes SE, Diccianni MB, Hank JA, Felder M, Birstler J, Sondel PM, Asgharzadeh S, Glade-Bender J, Katzenstein H, Maris JM, Park JR, Bagatell R
J Clin Oncol 2020 Jul 1;38(19):2160-2169. Epub 2020 Apr 28 doi: 10.1200/JCO.20.00203. PMID: 32343642Free PMC Article
Mody R, Naranjo A, Van Ryn C, Yu AL, London WB, Shulkin BL, Parisi MT, Servaes SE, Diccianni MB, Sondel PM, Bender JG, Maris JM, Park JR, Bagatell R
Lancet Oncol 2017 Jul;18(7):946-957. Epub 2017 May 23 doi: 10.1016/S1470-2045(17)30355-8. PMID: 28549783Free PMC Article
Steineck A, MacKenzie JD, Twist CJ
Pediatr Blood Cancer 2016 Nov;63(11):2050-3. Epub 2016 Jul 11 doi: 10.1002/pbc.26124. PMID: 27399265
Weiss B, Vora A, Huberty J, Hawkins RA, Matthay KK
J Pediatr Hematol Oncol 2003 Jul;25(7):543-7. doi: 10.1097/00043426-200307000-00009. PMID: 12847321

Clinical prediction guides

Heczey A, Courtney AN, Montalbano A, Robinson S, Liu K, Li M, Ghatwai N, Dakhova O, Liu B, Raveh-Sadka T, Chauvin-Fleurence CN, Xu X, Ngai H, Di Pierro EJ, Savoldo B, Dotti G, Metelitsa LS
Nat Med 2020 Nov;26(11):1686-1690. Epub 2020 Oct 12 doi: 10.1038/s41591-020-1074-2. PMID: 33046868
Mody R, Yu AL, Naranjo A, Zhang FF, London WB, Shulkin BL, Parisi MT, Servaes SE, Diccianni MB, Hank JA, Felder M, Birstler J, Sondel PM, Asgharzadeh S, Glade-Bender J, Katzenstein H, Maris JM, Park JR, Bagatell R
J Clin Oncol 2020 Jul 1;38(19):2160-2169. Epub 2020 Apr 28 doi: 10.1200/JCO.20.00203. PMID: 32343642Free PMC Article
McGregor LM, Stewart CF, Crews KR, Tagen M, Wozniak A, Wu J, McCarville MB, Navid F, Santana VM, Houghton PJ, Furman WL, Rodriguez-Galindo C
Pediatr Blood Cancer 2012 Mar;58(3):372-9. Epub 2011 Apr 20 doi: 10.1002/pbc.23075. PMID: 21509928Free PMC Article
Matthay KK, Quach A, Huberty J, Franc BL, Hawkins RA, Jackson H, Groshen S, Shusterman S, Yanik G, Veatch J, Brophy P, Villablanca JG, Maris JM
J Clin Oncol 2009 Mar 1;27(7):1020-5. Epub 2009 Jan 26 doi: 10.1200/JCO.2007.15.7628. PMID: 19171714Free PMC Article
Modak S, Cheung NK
Cancer Invest 2007 Feb;25(1):67-77. doi: 10.1080/07357900601130763. PMID: 17364560

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