Repeated infections of the urinary tract.

Failure to thrive (FTT) refers to a child whose physical growth is substantially below the norm.

A persistent cough, defined as a cough lasting longer than eight weeks in adults or longer than four weeks in children.

An increased susceptibility to upper respiratory tract infections as manifested by a history of recurrent upper respiratory tract infections (running ears - otitis, sinusitis, pharyngitis, tonsillitis).

An increased susceptibility to pneumonia as manifested by a history of recurrent episodes of pneumonia.

Asthma is characterized by increased responsiveness of the tracheobronchial tree to multiple stimuli, leading to narrowing of the air passages with resultant dyspnea, cough, and wheezing.

Increased number of neutrophils circulating in blood.

Increased susceptibility to otitis media, as manifested by recurrent episodes of otitis media.

Normal peripheral blood lymphocytes, when stimulated by phytohemagglutinin (PHA) are cytotoxic for homologous and heterologous cells but not for autologous cells in monolayer culture. The cytotoxic effect is thought to be indicative of the immunological competence of the lymphocytes.

A red eruption of the skin.