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Glottis carcinoma

MedGen UID:
152820
•Concept ID:
C0740083
•
Neoplastic Process
Synonyms: Cancer of Glottis; Cancer of the Glottis; Carcinoma of glottis; Carcinoma of Glottis; carcinoma of glottis; Carcinoma of the Glottis; carcinoma of the glottis; Glottic Carcinoma; glottic carcinoma; Glottis Cancer; Glottis Carcinoma; glottis carcinoma
SNOMED CT: Carcinoma of glottis (372103002)
 
Monarch Initiative: MONDO:0002355

Definition

A carcinoma of the larynx that arises from the glottic area. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGlottis carcinoma

Professional guidelines

PubMed

Surgical Treatment of Early Glottic Cancer.
Silver JA, Turkdogan S, Roy CF, Kost KM
Otolaryngol Clin North Am 2023 Apr;56(2):259-273. doi: 10.1016/j.otc.2022.12.009. PMID: 37030939
Treatment of early-stage laryngeal cancer: A comparison of treatment options.
Baird BJ, Sung CK, Beadle BM, Divi V
Oral Oncol 2018 Dec;87:8-16. Epub 2018 Oct 16 doi: 10.1016/j.oraloncology.2018.09.012. PMID: 30527248
Evidence-based practice: management of glottic cancer.
Hartl DM
Otolaryngol Clin North Am 2012 Oct;45(5):1143-61. Epub 2012 Jul 31 doi: 10.1016/j.otc.2012.06.014. PMID: 22980690

Recent clinical studies

Etiology

Predictive value of pathological carcinoma size in patients with T2 glottic laryngeal squamous cell carcinoma.
Zhou J, Zhu X, Yang Y, Zhou L, Gong H, Xu C, Tao L
Acta Otolaryngol 2023 Apr;143(4):317-321. Epub 2023 Mar 30 doi: 10.1080/00016489.2023.2188083. PMID: 36994848
Comparison Between Early Glottic Carcinoma and Epithelial Dysplastic Lesions of the Vocal Fold Via Voice Analysis.
Kang YA, Chang JW, Won HR, Koo BS
J Voice 2021 Nov;35(6):919-923. Epub 2020 Apr 24 doi: 10.1016/j.jvoice.2020.03.005. PMID: 32336569
Healing process following laser cordectomy of early glottis carcinoma from endoscopic view.
Shen L, Xu L, Wang Q, Fan GK
Lasers Surg Med 2016 Jul;48(5):483-9. Epub 2016 Feb 22 doi: 10.1002/lsm.22492. PMID: 26900138
Influence of the vocal cord mobility in salvage surgery after radiotherapy for early-stage squamous cell carcinoma of the glottic larynx.
Gorphe P, Blanchard P, Temam S, Janot F
Eur Arch Otorhinolaryngol 2015 Oct;272(10):3013-8. Epub 2014 Sep 14 doi: 10.1007/s00405-014-3286-x. PMID: 25218197
Definitive radiotherapy for early (T1-T2) glottic squamous cell carcinoma: a 20 year Cleveland Clinic experience.
Khan MK, Koyfman SA, Hunter GK, Reddy CA, Saxton JP
Radiat Oncol 2012 Nov 19;7:193. doi: 10.1186/1748-717X-7-193. PMID: 23164282Free PMC Article

Diagnosis

Comparison Between Early Glottic Carcinoma and Epithelial Dysplastic Lesions of the Vocal Fold Via Voice Analysis.
Kang YA, Chang JW, Won HR, Koo BS
J Voice 2021 Nov;35(6):919-923. Epub 2020 Apr 24 doi: 10.1016/j.jvoice.2020.03.005. PMID: 32336569
Successful treatment of radiation-induced mucositis with proton pump inhibitor administration: A report of two laryngeal cancer cases.
Eguchi K, Suzuki M, Ida S, Kudo S, Ando K, Ebara T, Higuchi K
Auris Nasus Larynx 2017 Feb;44(1):122-125. Epub 2016 Jun 2 doi: 10.1016/j.anl.2016.05.006. PMID: 27264874
Influence of the vocal cord mobility in salvage surgery after radiotherapy for early-stage squamous cell carcinoma of the glottic larynx.
Gorphe P, Blanchard P, Temam S, Janot F
Eur Arch Otorhinolaryngol 2015 Oct;272(10):3013-8. Epub 2014 Sep 14 doi: 10.1007/s00405-014-3286-x. PMID: 25218197
Nonvibrating segment predicting glottis carcinoma.
Vukasinović M, Djukić V, Stanković P, Krejović-Trivić S, Milovanović J, Mikić A, Ugrinović A, Dragisić M
Acta Chir Iugosl 2009;56(3):61-4. doi: 10.2298/aci0903061v. PMID: 20218104

Therapy

Successful treatment of radiation-induced mucositis with proton pump inhibitor administration: A report of two laryngeal cancer cases.
Eguchi K, Suzuki M, Ida S, Kudo S, Ando K, Ebara T, Higuchi K
Auris Nasus Larynx 2017 Feb;44(1):122-125. Epub 2016 Jun 2 doi: 10.1016/j.anl.2016.05.006. PMID: 27264874
Healing process following laser cordectomy of early glottis carcinoma from endoscopic view.
Shen L, Xu L, Wang Q, Fan GK
Lasers Surg Med 2016 Jul;48(5):483-9. Epub 2016 Feb 22 doi: 10.1002/lsm.22492. PMID: 26900138
Influence of the vocal cord mobility in salvage surgery after radiotherapy for early-stage squamous cell carcinoma of the glottic larynx.
Gorphe P, Blanchard P, Temam S, Janot F
Eur Arch Otorhinolaryngol 2015 Oct;272(10):3013-8. Epub 2014 Sep 14 doi: 10.1007/s00405-014-3286-x. PMID: 25218197
Oncological and functional outcome after transoral 532-nm pulsed potassium-titanyl-phosphate laser surgery for T1a glottic carcinoma.
Murono S, Endo K, Kondo S, Wakisaka N, Yoshizaki T
Lasers Med Sci 2013 Feb;28(2):615-9. Epub 2012 May 17 doi: 10.1007/s10103-012-1121-4. PMID: 22588685
Definitive radiotherapy for early (T1-T2) glottic squamous cell carcinoma: a 20 year Cleveland Clinic experience.
Khan MK, Koyfman SA, Hunter GK, Reddy CA, Saxton JP
Radiat Oncol 2012 Nov 19;7:193. doi: 10.1186/1748-717X-7-193. PMID: 23164282Free PMC Article

Prognosis

Predictive value of pathological carcinoma size in patients with T2 glottic laryngeal squamous cell carcinoma.
Zhou J, Zhu X, Yang Y, Zhou L, Gong H, Xu C, Tao L
Acta Otolaryngol 2023 Apr;143(4):317-321. Epub 2023 Mar 30 doi: 10.1080/00016489.2023.2188083. PMID: 36994848
Healing process following laser cordectomy of early glottis carcinoma from endoscopic view.
Shen L, Xu L, Wang Q, Fan GK
Lasers Surg Med 2016 Jul;48(5):483-9. Epub 2016 Feb 22 doi: 10.1002/lsm.22492. PMID: 26900138
Influence of the vocal cord mobility in salvage surgery after radiotherapy for early-stage squamous cell carcinoma of the glottic larynx.
Gorphe P, Blanchard P, Temam S, Janot F
Eur Arch Otorhinolaryngol 2015 Oct;272(10):3013-8. Epub 2014 Sep 14 doi: 10.1007/s00405-014-3286-x. PMID: 25218197
Definitive radiotherapy for early (T1-T2) glottic squamous cell carcinoma: a 20 year Cleveland Clinic experience.
Khan MK, Koyfman SA, Hunter GK, Reddy CA, Saxton JP
Radiat Oncol 2012 Nov 19;7:193. doi: 10.1186/1748-717X-7-193. PMID: 23164282Free PMC Article
Nonvibrating segment predicting glottis carcinoma.
Vukasinović M, Djukić V, Stanković P, Krejović-Trivić S, Milovanović J, Mikić A, Ugrinović A, Dragisić M
Acta Chir Iugosl 2009;56(3):61-4. doi: 10.2298/aci0903061v. PMID: 20218104

Clinical prediction guides

Predictive value of pathological carcinoma size in patients with T2 glottic laryngeal squamous cell carcinoma.
Zhou J, Zhu X, Yang Y, Zhou L, Gong H, Xu C, Tao L
Acta Otolaryngol 2023 Apr;143(4):317-321. Epub 2023 Mar 30 doi: 10.1080/00016489.2023.2188083. PMID: 36994848
Successful treatment of radiation-induced mucositis with proton pump inhibitor administration: A report of two laryngeal cancer cases.
Eguchi K, Suzuki M, Ida S, Kudo S, Ando K, Ebara T, Higuchi K
Auris Nasus Larynx 2017 Feb;44(1):122-125. Epub 2016 Jun 2 doi: 10.1016/j.anl.2016.05.006. PMID: 27264874
Healing process following laser cordectomy of early glottis carcinoma from endoscopic view.
Shen L, Xu L, Wang Q, Fan GK
Lasers Surg Med 2016 Jul;48(5):483-9. Epub 2016 Feb 22 doi: 10.1002/lsm.22492. PMID: 26900138
Oncological and functional outcome after transoral 532-nm pulsed potassium-titanyl-phosphate laser surgery for T1a glottic carcinoma.
Murono S, Endo K, Kondo S, Wakisaka N, Yoshizaki T
Lasers Med Sci 2013 Feb;28(2):615-9. Epub 2012 May 17 doi: 10.1007/s10103-012-1121-4. PMID: 22588685
Definitive radiotherapy for early (T1-T2) glottic squamous cell carcinoma: a 20 year Cleveland Clinic experience.
Khan MK, Koyfman SA, Hunter GK, Reddy CA, Saxton JP
Radiat Oncol 2012 Nov 19;7:193. doi: 10.1186/1748-717X-7-193. PMID: 23164282Free PMC Article

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