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Serotonin syndrome

MedGen UID:
152119
Concept ID:
C0699828
Injury or Poisoning
Synonyms: Serotonin Syndrome; Serotonin Syndromes; Syndrome, Serotonin; Syndromes, Serotonin
SNOMED CT: Serotonin syndrome (371089000); Serotonergic syndrome (371089000)
 
Monarch Initiative: MONDO:0018546

Definition

Serotoninergic syndrome is characterized by an excess of serotonin in the central nervous system, associated with the use of various agents, including selective serotonin reuptake inhibitors (SSRIs). [from MONDO]

Professional guidelines

PubMed

Locke AB, Kirst N, Shultz CG
Am Fam Physician 2015 May 1;91(9):617-24. PMID: 25955736
Thomas SJ, Shin M, McInnis MG, Bostwick JR
Pharmacotherapy 2015 Apr;35(4):433-49. doi: 10.1002/phar.1576. PMID: 25884531
Perry PJ, Wilborn CA
Ann Clin Psychiatry 2012 May;24(2):155-62. PMID: 22563571

Recent systematic reviews

Elbarbry F, Moshirian N
Eur J Clin Pharmacol 2023 Jul;79(7):875-883. Epub 2023 May 2 doi: 10.1007/s00228-023-03500-9. PMID: 37129603
Daziani G, Lo Faro AF, Montana V, Goteri G, Pesaresi M, Bambagiotti G, Montanari E, Giorgetti R, Montana A
Int J Mol Sci 2023 Mar 25;24(7) doi: 10.3390/ijms24076230. PMID: 37047201Free PMC Article
Roulet L, Rollason V, Desmeules J, Piguet V
Drugs 2021 Jul;81(11):1257-1272. Epub 2021 Jul 1 doi: 10.1007/s40265-021-01515-z. PMID: 34196947Free PMC Article
Wang M, Wang W, Gao Z, Yin X, Chen T, Jiang Z, Wang Z
Clin Auton Res 2021 Aug;31(4):529-542. Epub 2021 Apr 7 doi: 10.1007/s10286-021-00801-w. PMID: 33826041Free PMC Article
Channell JS, Schug S
Pain Manag 2018 Sep 1;8(5):327-339. Epub 2018 Aug 6 doi: 10.2217/pmt-2018-0027. PMID: 30079795

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