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Colon Hyperplastic Polyp

MedGen UID:
149276
•Concept ID:
C0742608
•
Disease or Syndrome
Synonyms: Colon HP; Colon Metaplastic Polyp; Colon MP; Colonic Hyperplastic Polyp; Hyperplastic Colonic Polyp; Hyperplastic Polyp of Colon; Hyperplastic Polyp of the Colon; Metaplastic Colon Polyp; Metaplastic Colonic Polyp; Metaplastic Polyp of Colon; Metaplastic Polyp of the Colon

Definition

A serrated polypoid lesion that arises in the colon. It is usually found in the distant colon and it rarely produces symptoms. This group includes goblet cell rich, mucin poor, and microvesicular hyperplastic polyps. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVColon Hyperplastic Polyp

Professional guidelines

PubMed

Sessile serrated lesions: Clinicopathological characteristics, endoscopic diagnosis, and management.
Murakami T, Kurosawa T, Fukushima H, Shibuya T, Yao T, Nagahara A
Dig Endosc 2022 Sep;34(6):1096-1109. Epub 2022 Mar 29 doi: 10.1111/den.14273. PMID: 35352394
The Differential Diagnosis of Colorectal Polyps Using Colon Capsule Endoscopy.
Nakazawa K, Nouda S, Kakimoto K, Kinoshita N, Tanaka Y, Tawa H, Koshiba R, Naka Y, Hirata Y, Ota K, Kawakami K, Takeuchi T, Inoue T, Miyazaki T, Sanomura M, Nakamura S, Saito Y, Higuchi K
Intern Med 2021 Jun 15;60(12):1805-1812. Epub 2021 Jan 15 doi: 10.2169/internalmedicine.6446-20. PMID: 33456043Free PMC Article
Terminology, Molecular Features, Epidemiology, and Management of Serrated Colorectal Neoplasia.
Crockett SD, Nagtegaal ID
Gastroenterology 2019 Oct;157(4):949-966.e4. Epub 2019 Jul 16 doi: 10.1053/j.gastro.2019.06.041. PMID: 31323292

Recent clinical studies

Diagnosis

Initial analyses of colon cancer-specific antigen (CCSA)-3 and CCSA-4 as colorectal cancer-associated serum markers.
Leman ES, Schoen RE, Weissfeld JL, Cannon GW, Sokoll LJ, Chan DW, Getzenberg RH
Cancer Res 2007 Jun 15;67(12):5600-5. doi: 10.1158/0008-5472.CAN-07-0649. PMID: 17575123

Clinical prediction guides

Angiogenesis in colon hyperplastic polyp.
Sano Y, Maeda N, Kanzaki A, Fujii T, Ochiai A, Takenoshita S, Takebayashi Y
Cancer Lett 2005 Feb 10;218(2):223-8. doi: 10.1016/S0304-3835(03)00183-6. PMID: 15670900

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