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Neuroma

MedGen UID:
14352
•Concept ID:
C0027858
•
Neoplastic Process
Synonym: Neuromas
SNOMED CT: Neuroma (443892003); Neuroma (1163436007)
 
HPO: HP:0030430
Monarch Initiative: MONDO:0002173

Definition

A tumor made up of nerve cells and nerve fibers. [from HPO]

Professional guidelines

PubMed

Differential Diagnosis of Metatarsalgia.
Afonso PD, Britto SV, Spritzer CE, Martins E Souza P
Semin Musculoskelet Radiol 2023 Jun;27(3):337-350. Epub 2023 May 25 doi: 10.1055/s-0043-1764388. PMID: 37230133
Neuropathic Pain: From Mechanisms to Treatment.
Finnerup NB, Kuner R, Jensen TS
Physiol Rev 2021 Jan 1;101(1):259-301. Epub 2020 Jun 25 doi: 10.1152/physrev.00045.2019. PMID: 32584191
Heel Pain: Diagnosis and Management.
Tu P
Am Fam Physician 2018 Jan 15;97(2):86-93. PMID: 29365222

Recent clinical studies

Etiology

Relationship between radiofrequency-electromagnetic radiation from cellular phones and brain tumor: meta-analyses using various proxies for RF-EMR exposure-outcome assessment.
Moon J, Kwon J, Mun Y
Environ Health 2024 Oct 10;23(1):82. doi: 10.1186/s12940-024-01117-8. PMID: 39390576Free PMC Article
The effect of exposure to radiofrequency fields on cancer risk in the general and working population: A systematic review of human observational studies - Part I: Most researched outcomes.
Karipidis K, Baaken D, Loney T, Blettner M, Brzozek C, Elwood M, Narh C, Orsini N, Röösli M, Paulo MS, Lagorio S
Environ Int 2024 Sep;191:108983. Epub 2024 Aug 30 doi: 10.1016/j.envint.2024.108983. PMID: 39241333

Diagnosis

The effect of exposure to radiofrequency fields on cancer risk in the general and working population: A systematic review of human observational studies - Part I: Most researched outcomes.
Karipidis K, Baaken D, Loney T, Blettner M, Brzozek C, Elwood M, Narh C, Orsini N, Röösli M, Paulo MS, Lagorio S
Environ Int 2024 Sep;191:108983. Epub 2024 Aug 30 doi: 10.1016/j.envint.2024.108983. PMID: 39241333

Therapy

Common Painful Foot and Ankle Conditions: A Review.
Cooper MT
JAMA 2023 Dec 19;330(23):2285-2294. doi: 10.1001/jama.2023.23906. PMID: 38112812
A Critical Overview of Targeted Therapies for Vestibular Schwannoma.
Tamura R, Toda M
Int J Mol Sci 2022 May 13;23(10) doi: 10.3390/ijms23105462. PMID: 35628268Free PMC Article
Vestibular Schwannomas.
Carlson ML, Link MJ
N Engl J Med 2021 Apr 8;384(14):1335-1348. doi: 10.1056/NEJMra2020394. PMID: 33826821
Non-surgical treatments for Morton's neuroma: A systematic review.
Thomson L, Aujla RS, Divall P, Bhatia M
Foot Ankle Surg 2020 Oct;26(7):736-743. Epub 2019 Nov 2 doi: 10.1016/j.fas.2019.09.009. PMID: 31718949
Treatment of Morton's neuroma: A systematic review.
Valisena S, Petri GJ, Ferrero A
Foot Ankle Surg 2018 Aug;24(4):271-281. Epub 2017 Apr 5 doi: 10.1016/j.fas.2017.03.010. PMID: 29409240

Prognosis

SRS for Vestibular Schwannomas - Current Status.
Pattankar S, Pasricha P, Misra BK
Neurol India 2023 Mar-Apr;71(Supplement):S115-S122. doi: 10.4103/0028-3886.373653. PMID: 37026342
Vestibular Schwannomas.
Carlson ML, Link MJ
N Engl J Med 2021 Apr 8;384(14):1335-1348. doi: 10.1056/NEJMra2020394. PMID: 33826821
Hearing preservation: microsurgery.
Kari E, Friedman RA
Curr Opin Otolaryngol Head Neck Surg 2012 Oct;20(5):358-66. doi: 10.1097/MOO.0b013e3283579673. PMID: 22929113
Acoustic schwannoma.
Chandler CL, Ramsden RT
Br J Hosp Med 1993 Mar 3-16;49(5):335-43. PMID: 8472085
Morton's neuroma.
Viladot A
Int Orthop 1992;16(3):294-6. doi: 10.1007/BF00182715. PMID: 1428347

Clinical prediction guides

Interdigital Commissural Approach for Morton's Neuroma.
Yañez Arauz JM
Foot Ankle Int 2020 Oct;41(10):1226-1233. Epub 2020 Jul 16 doi: 10.1177/1071100720936599. PMID: 32674597
Fatigue in patients with vestibular schwannoma.
Dhayalan D, Lund-Johansen M, Finnkirk M, Tveiten ØV
Acta Neurochir (Wien) 2019 Sep;161(9):1809-1816. Epub 2019 Jul 18 doi: 10.1007/s00701-019-04003-2. PMID: 31321539
Growth rate of vestibular schwannoma.
Paldor I, Chen AS, Kaye AH
J Clin Neurosci 2016 Oct;32:1-8. Epub 2016 Jul 20 doi: 10.1016/j.jocn.2016.05.003. PMID: 27450283
Hearing preservation: microsurgery.
Kari E, Friedman RA
Curr Opin Otolaryngol Head Neck Surg 2012 Oct;20(5):358-66. doi: 10.1097/MOO.0b013e3283579673. PMID: 22929113
Acoustic neuroma diagnosis.
Kharkheli ESh, Shurygina LS, Davitashvili OZ, Tushishvili MA, Chibalashvili NIu, Korteweg MP, Kevanishvili ZSh
Georgian Med News 2011 Mar;(192):21-8. PMID: 21525535

Recent systematic reviews

Treatment for vestibular schwannoma: Systematic review and single arm meta-analysis.
Thai NLB, Mai NY, Vuong NL, Tin NM, Karam D, Refaey MA, Shahin KM, Soliman AL, Al Khudari R, Thuan TM, Sabbah GM, El-Qushayri AE, Karimzadeh S, Hirayama K, Huy NT
Am J Otolaryngol 2022 Mar-Apr;43(2):103337. Epub 2021 Dec 20 doi: 10.1016/j.amjoto.2021.103337. PMID: 34973662
Extracorporeal Shockwave Therapy for Foot and Ankle Disorders: A Systematic Review and Meta-Analysis.
Nazim B Tengku Yusof T, Seow D, Vig KS
J Am Podiatr Med Assoc 2022 May-Jun;112(3) doi: 10.7547/18-191. PMID: 34878537
Non-surgical treatments for Morton's neuroma: A systematic review.
Thomson L, Aujla RS, Divall P, Bhatia M
Foot Ankle Surg 2020 Oct;26(7):736-743. Epub 2019 Nov 2 doi: 10.1016/j.fas.2019.09.009. PMID: 31718949
The effectiveness of non-surgical interventions for common plantar digital compressive neuropathy (Morton's neuroma): a systematic review and meta-analysis.
Matthews BG, Hurn SE, Harding MP, Henry RA, Ware RS
J Foot Ankle Res 2019;12:12. Epub 2019 Feb 13 doi: 10.1186/s13047-019-0320-7. PMID: 30809275Free PMC Article
Treatment of Morton's neuroma: A systematic review.
Valisena S, Petri GJ, Ferrero A
Foot Ankle Surg 2018 Aug;24(4):271-281. Epub 2017 Apr 5 doi: 10.1016/j.fas.2017.03.010. PMID: 29409240

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