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Bilateral alveolar cleft of maxilla

MedGen UID:
1379910
•Concept ID:
C4477071
•
Congenital Abnormality
HPO: HP:0410034

Definition

Nonmidline alveolar cleft of the maxilla. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBilateral alveolar cleft of maxilla

Professional guidelines

PubMed

Clinical Finding and Management of 12 Orofacial Clefts Cases With Nevoid Basal Cell Carcinoma Syndrome.
Mui Lee L, Ma L, Jun Li T
Cleft Palate Craniofac J 2017 May;54(3):338-342. doi: 10.1597/14-323. PMID: 28471735
Management of the premaxilla in the treatment of bilateral cleft of lip and palate: what can the literature tell us?
Bittermann GK, de Ruiter AP, Janssen NG, Bittermann AJ, van der Molen AM, van Es RJ, Rosenberg AJ, Koole R
Clin Oral Investig 2016 Mar;20(2):207-17. Epub 2015 Sep 16 doi: 10.1007/s00784-015-1589-y. PMID: 26374747Free PMC Article
Combined orthodontic-surgical treatment of alveolar clefts.
Enemark H, Sindet-Pedersen S, Bundgaard M, Simonsen EK
Ann Plast Surg 1988 Aug;21(2):127-33. doi: 10.1097/00000637-198808000-00006. PMID: 3052234

Recent clinical studies

Etiology

Maxillary arch dimensions in bilateral cleft lip and palate in the age 0-5 months.
Peixoto AP, Miranda F, de Oliveira Pinto R, Ribeiro TTC, Lara FSS, Machado FMC, Garib D
Orthod Craniofac Res 2024 Dec;27(6):903-908. Epub 2024 Jul 14 doi: 10.1111/ocr.12836. PMID: 39003677
Prognosis of Maxillary Central Incisors in Patients with Bilateral Cleft Lip/Palate.
Green MA, Ritchie C, Flanagan S, Nuzzi L, Padwa BL
Cleft Palate Craniofac J 2024 Sep;61(9):1543-1547. Epub 2023 May 9 doi: 10.1177/10556656231175337. PMID: 37160755
Dynamic Cleft Maxillary Orthopedics and Periosteoplasty.
Lukash FN, Shikowitz-Behr LB, Schwartz M, Tuminelli F
Ann Plast Surg 2018 Jan;80(1):40-44. doi: 10.1097/SAP.0000000000001187. PMID: 28737562
Bite force of children with repaired unilateral and bilateral cleft lip and palate.
Garcia MA, Rios D, Honório HM, Trindade-Suedam IK
Arch Oral Biol 2016 Aug;68:83-7. Epub 2016 Mar 31 doi: 10.1016/j.archoralbio.2016.03.019. PMID: 27107381
Primary Premaxillary Setback and Repair of Bilateral Complete Cleft Lip: Indications, Technique, and Outcomes.
Vyas RM, Kim DC, Padwa BL, Mulliken JB
Cleft Palate Craniofac J 2016 May;53(3):302-8. Epub 2015 Nov 17 doi: 10.1597/14-099. PMID: 26575966

Diagnosis

Prognosis of Maxillary Central Incisors in Patients with Bilateral Cleft Lip/Palate.
Green MA, Ritchie C, Flanagan S, Nuzzi L, Padwa BL
Cleft Palate Craniofac J 2024 Sep;61(9):1543-1547. Epub 2023 May 9 doi: 10.1177/10556656231175337. PMID: 37160755
Segmental Maxillary Osteotomy to Close Wide Alveolar Clefts.
Wilson AT, Wu RT, Sawh-Martinez R, Steinbacher DM
J Oral Maxillofac Surg 2019 Apr;77(4):850.e1-850.e5. Epub 2018 Nov 26 doi: 10.1016/j.joms.2018.11.011. PMID: 30576673
First-Trimester Sonographic Evaluation of Palatine Clefts: A Novel Diagnostic Approach.
Lakshmy SR, Deepa S, Rose N, Mookan S, Agnees J
J Ultrasound Med 2017 Jul;36(7):1397-1414. Epub 2017 Apr 18 doi: 10.7863/ultra.16.05084. PMID: 28417474
Premaxillary Repositioning in the Severe Form of Bilateral Cleft Lip and Palate.
Koh KS, Han WY, Jeong WS, Oh TS, Kwon SM, Choi JW
J Craniofac Surg 2016 Sep;27(6):1440-4. doi: 10.1097/SCS.0000000000002729. PMID: 27300460
Treatment algorithm for bilateral alveolar cleft based on the position of the premaxilla and the width of the alveolar gap.
Koh KS, Kim H, Oh TS, Kwon SM, Choi JW
J Plast Reconstr Aesthet Surg 2013 Sep;66(9):1212-8. Epub 2013 May 21 doi: 10.1016/j.bjps.2013.04.060. PMID: 23702194

Therapy

Polyphosphate (PolyP) for alveolar cleft repair: study protocol for a pilot randomized controlled trial.
Alkaabi SA, Natsir Kalla DS, Alsabri GA, Fauzi A, Tajrin A, Müller WEG, Schröder HC, Wang XG, Forouzanfar T, Helder MN, Ruslin M
Trials 2021 Jun 14;22(1):393. doi: 10.1186/s13063-021-05325-2. PMID: 34127045Free PMC Article
Bite force of children with repaired unilateral and bilateral cleft lip and palate.
Garcia MA, Rios D, Honório HM, Trindade-Suedam IK
Arch Oral Biol 2016 Aug;68:83-7. Epub 2016 Mar 31 doi: 10.1016/j.archoralbio.2016.03.019. PMID: 27107381
Interdisciplinary treatment of an adult with complete bilateral cleft lip and palate.
Okada W, Fukui T, Saito T, Ohkubo C, Hamada Y, Nakamura Y
Am J Orthod Dentofacial Orthop 2012 Apr;141(4 Suppl):S149-58. doi: 10.1016/j.ajodo.2011.07.025. PMID: 22449595
Nonunion of the external maxillary distraction in cleft lip and palate: analysis of possible reasons.
He D, Genecov DG, Barcelo R
J Oral Maxillofac Surg 2010 Oct;68(10):2402-11. doi: 10.1016/j.joms.2009.09.018. PMID: 20605305
Maxillary alveolar cleft repair in dogs using recombinant human bone morphogenetic protein-2 and a polymer carrier.
Mayer M, Hollinger J, Ron E, Wozney J
Plast Reconstr Surg 1996 Aug;98(2):247-59. doi: 10.1097/00006534-199608000-00006. PMID: 8764712

Prognosis

Adaptable cascaded registration for personalized maxilla completion and cleft defect volume estimation.
Zhang Y, Pei Y, Guo Y, Chen S, Zhou ZB, Xu T, Zha H
Med Phys 2024 Jun;51(6):4283-4296. Epub 2024 Mar 31 doi: 10.1002/mp.17046. PMID: 38555877
Prognosis of Maxillary Central Incisors in Patients with Bilateral Cleft Lip/Palate.
Green MA, Ritchie C, Flanagan S, Nuzzi L, Padwa BL
Cleft Palate Craniofac J 2024 Sep;61(9):1543-1547. Epub 2023 May 9 doi: 10.1177/10556656231175337. PMID: 37160755
The First-Year Follow-Up of a Cleft Lip and Palate Patient Treated With Nasoalveolar Molding (NAM).
Oliveira NV, Tou GAA, Silva RS, Rezende SE, Pretti H, Macari S
Braz Dent J 2020 Jan-Apr;31(2):190-196. doi: 10.1590/0103-6440202003040. PMID: 32556020
Dynamic Cleft Maxillary Orthopedics and Periosteoplasty.
Lukash FN, Shikowitz-Behr LB, Schwartz M, Tuminelli F
Ann Plast Surg 2018 Jan;80(1):40-44. doi: 10.1097/SAP.0000000000001187. PMID: 28737562
Primary Premaxillary Setback and Repair of Bilateral Complete Cleft Lip: Indications, Technique, and Outcomes.
Vyas RM, Kim DC, Padwa BL, Mulliken JB
Cleft Palate Craniofac J 2016 May;53(3):302-8. Epub 2015 Nov 17 doi: 10.1597/14-099. PMID: 26575966

Clinical prediction guides

Adaptable cascaded registration for personalized maxilla completion and cleft defect volume estimation.
Zhang Y, Pei Y, Guo Y, Chen S, Zhou ZB, Xu T, Zha H
Med Phys 2024 Jun;51(6):4283-4296. Epub 2024 Mar 31 doi: 10.1002/mp.17046. PMID: 38555877
Retrospective analysis of clinical outcomes in bilateral cleft lip and palate patients after secondary alveolar bone grafting and premaxilla osteotomy, using a new dento-maxillary scoring system.
Bittermann GKP, van Es RJJ, de Ruiter AP, Bittermann AJN, Koole R, Rosenberg AJWP
J Craniomaxillofac Surg 2021 Feb;49(2):110-117. Epub 2020 Dec 15 doi: 10.1016/j.jcms.2020.12.006. PMID: 33357967
Segmental Maxillary Osteotomy to Close Wide Alveolar Clefts.
Wilson AT, Wu RT, Sawh-Martinez R, Steinbacher DM
J Oral Maxillofac Surg 2019 Apr;77(4):850.e1-850.e5. Epub 2018 Nov 26 doi: 10.1016/j.joms.2018.11.011. PMID: 30576673
Premaxillary Repositioning in the Severe Form of Bilateral Cleft Lip and Palate.
Koh KS, Han WY, Jeong WS, Oh TS, Kwon SM, Choi JW
J Craniofac Surg 2016 Sep;27(6):1440-4. doi: 10.1097/SCS.0000000000002729. PMID: 27300460
Bite force of children with repaired unilateral and bilateral cleft lip and palate.
Garcia MA, Rios D, Honório HM, Trindade-Suedam IK
Arch Oral Biol 2016 Aug;68:83-7. Epub 2016 Mar 31 doi: 10.1016/j.archoralbio.2016.03.019. PMID: 27107381

Recent systematic reviews

Effects of labial adhesion on maxillary arch dimensions and nasolabial esthetics in cleft lip and palate: a systematic review.
Thierens L, Brusselaers N, De Roo N, De Pauw G
Oral Dis 2017 Oct;23(7):889-896. Epub 2017 Jan 24 doi: 10.1111/odi.12613. PMID: 27878905

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