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Alveoli adenoma

MedGen UID:
137740
Concept ID:
C0334303
Neoplastic Process
Synonyms: Adenoma of Alveoli; adenoma of alveoli; Adenoma of the Alveoli; adenoma of the alveoli; adenoma, bronchioloalveolar, benign; Alveolar adenoma; Alveolar Adenoma; alveolar adenoma; alveolar adenoma (morphologic abnormality); alveoli adenoma
SNOMED CT: Alveolar adenoma (8097004)
 
Monarch Initiative: MONDO:0004428

Definition

A benign, well circumscribed lung neoplasm morphologically characterized by the presence of cystic spaces resembling alveoli, lined by a simple cuboidal epithelium. The cystic spaces are surrounded by a spindle cell stroma which may show myxoid changes. It is a solitary, usually peripheral lung lesion. Patients are usually asymptomatic and its discovery is an incidental finding during chest X-ray examination. Surgical excision is curative. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAlveoli adenoma

Recent clinical studies

Etiology

Panagiotou I, Kostikas K, Sampaziotis D, Kotoulas C
Interact Cardiovasc Thorac Surg 2012 Mar;14(3):335-7. Epub 2011 Dec 7 doi: 10.1093/icvts/ivr040. PMID: 22159242Free PMC Article
Kayser K, Seemann C, André S, Kugler C, Becker C, Dong X, Kaltner H, Gabius HJ
Pathol Res Pract 2000;196(2):81-7. doi: 10.1016/s0344-0338(00)80037-0. PMID: 10707363
Gruber UF
Eur Surg Res 1986;18(3-4):207-12. doi: 10.1159/000128527. PMID: 3720814
Doniach I
Clin Endocrinol Metab 1985 Nov;14(4):765-89. doi: 10.1016/s0300-595x(85)80077-3. PMID: 3002676
Greenberg SD
Hum Pathol 1983 Oct;14(10):901-12. doi: 10.1016/s0046-8177(83)80165-8. PMID: 6352461

Diagnosis

Rossi G, Caroli G, Caruso D, Stella F, Davoli F
Int J Surg Pathol 2021 Oct;29(7):775-779. Epub 2021 Feb 24 doi: 10.1177/1066896921997559. PMID: 33624546
Jones RM, VandenBussche CJ
Diagn Cytopathol 2020 Nov;48(11):1155-1161. Epub 2020 Aug 17 doi: 10.1002/dc.24568. PMID: 33469998
Wang X, Li WQ, Yan HZ, Li YM, He J, Liu HM, Yu HY
J Int Med Res 2013 Jun;41(3):895-906. Epub 2013 May 7 doi: 10.1177/0300060513477304. PMID: 23653367
Dirksen A
Clin Respir J 2008 Apr;2(2):129. doi: 10.1111/j.1752-699X.2007.00008.x. PMID: 20298319
Greenberg SD
Hum Pathol 1983 Oct;14(10):901-12. doi: 10.1016/s0046-8177(83)80165-8. PMID: 6352461

Therapy

Caniceiro BD, Latorre AO, Fukumasu H, Sanches DS, Haraguchi M, Górniak SL
J Immunotoxicol 2015 Jan-Mar;12(1):74-80. Epub 2014 Feb 19 doi: 10.3109/1547691X.2014.885619. PMID: 24552549
Schepers GW
Am J Ind Med 1995 Apr;27(4):593-606. doi: 10.1002/ajim.4700270413. PMID: 7793430
Gruber UF
Eur Surg Res 1986;18(3-4):207-12. doi: 10.1159/000128527. PMID: 3720814
Greenberg SD
Hum Pathol 1983 Oct;14(10):901-12. doi: 10.1016/s0046-8177(83)80165-8. PMID: 6352461
Webster I
S Afr Med J 1973 Feb 3;47(5):165-71. PMID: 4684243

Prognosis

Wang X, Li WQ, Yan HZ, Li YM, He J, Liu HM, Yu HY
J Int Med Res 2013 Jun;41(3):895-906. Epub 2013 May 7 doi: 10.1177/0300060513477304. PMID: 23653367
Panagiotou I, Kostikas K, Sampaziotis D, Kotoulas C
Interact Cardiovasc Thorac Surg 2012 Mar;14(3):335-7. Epub 2011 Dec 7 doi: 10.1093/icvts/ivr040. PMID: 22159242Free PMC Article
Allen TD, Zhu CQ, Jones KD, Yanagawa N, Tsao MS, Bishop JM
Cancer Res 2011 Mar 15;71(6):2212-21. doi: 10.1158/0008-5472.CAN-10-3590. PMID: 21406400Free PMC Article
Kayser K, Seemann C, André S, Kugler C, Becker C, Dong X, Kaltner H, Gabius HJ
Pathol Res Pract 2000;196(2):81-7. doi: 10.1016/s0344-0338(00)80037-0. PMID: 10707363
Jaffe LS
Arch Environ Health 1968 Feb;16(2):241-55. doi: 10.1080/00039896.1968.10665050. PMID: 4869112

Clinical prediction guides

Hill KS, Erdogan E, Khoor A, Walsh MP, Leitges M, Murray NR, Fields AP
Oncogene 2014 Apr 17;33(16):2134-44. Epub 2013 Apr 22 doi: 10.1038/onc.2013.147. PMID: 23604119Free PMC Article
Oda E, Nakamura Y, Yamamoto M, Kojiro M
Kurume Med J 2005;52(4):117-25. doi: 10.2739/kurumemedj.52.117. PMID: 16639982
Koujitani T, Yasuhara K, Tamura T, Onodera H, Takagi H, Takizawa T, Hirose M, Hayashi Y, Mitsumori K
J Toxicol Sci 2001 Aug;26(3):129-39. doi: 10.2131/jts.26.129. PMID: 11552296
Schroeder JA, Lee DC
J Mammary Gland Biol Neoplasia 1997 Apr;2(2):119-29. doi: 10.1023/a:1026347629876. PMID: 10882298
Lantuejoul S, Ferretti G, Negoescu A, Parent B, Brambilla E
Histopathology 1997 Jun;30(6):570-5. doi: 10.1046/j.1365-2559.1997.4600811.x. PMID: 9205862

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