U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Leakage of dye on fundus fluorescein angiography

MedGen UID:
1370943
•Concept ID:
C4476700
•
Finding
Synonym: Fluorescein leakage
 
HPO: HP:0025320

Definition

Leakage of fluorescein dye observed upon retinal fluorescein angiography. Areas of leakage can be appreciated as showing gradual enlargement with blurring of margins. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLeakage of dye on fundus fluorescein angiography

Professional guidelines

PubMed

Imaging Characteristics and Clinical Utility of Half-Dose versus Full-Dose Ultrawidefield Fundus Fluorescein Angiography.
Szigiato A, Sharma S, Singh S, Baynes K, Lowder C, Kaiser PK, Ehlers JP, Srivastava SK
Ophthalmol Retina 2024 Oct;8(10):981-986. Epub 2024 May 6 doi: 10.1016/j.oret.2024.04.024. PMID: 38719190
Clinical features and differential diagnosis of acute idiopathic blind spot enlargement syndrome.
Liu X, Chen B, Zhang M, Huang H
Eye Sci 2014 Sep;29(3):143-50. PMID: 26011969
Principles of treatment of choroidal neovascularization with photodynamic therapy in age-related macular degeneration.
Donati G, Kapetanios AD, Pournaras CJ
Semin Ophthalmol 1999 Mar;14(1):2-10. doi: 10.3109/08820539909056057. PMID: 10790570

Recent clinical studies

Etiology

Indocyanine Green Angiographic Assessment of Conjunctival Melanocytic Disorders.
Palme C, Wanner A, Romano V, Franchi A, Haas G, Kaye SB, Steger B
Cornea 2021 Dec 1;40(12):1519-1524. doi: 10.1097/ICO.0000000000002681. PMID: 33591034
Multimodal Imaging in the Diagnosis of Exophytic Juxtapapillary Retinal Capillary Hemangioblastoma.
Russell JF, Villegas VM, Schwartz SG, Weng CY, Davis JL, Flynn HW Jr, Harbour JW
Am J Ophthalmol 2021 May;225:128-136. Epub 2021 Jan 12 doi: 10.1016/j.ajo.2021.01.002. PMID: 33450232
Findings of OCT-angiography compared to fluorescein and indocyanine green angiography in central serous chorioretinopathy.
Min JY, Lv Y, Yu S, Gong YY
Lasers Surg Med 2018 Dec;50(10):987-993. Epub 2018 Jun 12 doi: 10.1002/lsm.22952. PMID: 29896889
OCT Angiography Compared to Fluorescein and Indocyanine Green Angiography in Chronic Central Serous Chorioretinopathy.
Teussink MM, Breukink MB, van Grinsven MJ, Hoyng CB, Klevering BJ, Boon CJ, de Jong EK, Theelen T
Invest Ophthalmol Vis Sci 2015 Aug;56(9):5229-37. doi: 10.1167/iovs.15-17140. PMID: 26244299
Fully automatic segmentation of fluorescein leakage in subjects with diabetic macular edema.
Rabbani H, Allingham MJ, Mettu PS, Cousins SW, Farsiu S
Invest Ophthalmol Vis Sci 2015 Jan 29;56(3):1482-92. doi: 10.1167/iovs.14-15457. PMID: 25634978Free PMC Article

Diagnosis

Clinical and imaging features of sympathetic ophthalmia and efficacy of the current therapy.
Zhao X, Zhao Q, Meng L, Zhang W, Chen Y
Acta Ophthalmol 2022 Nov;100(7):e1403-e1411. Epub 2022 Jan 27 doi: 10.1111/aos.15095. PMID: 35088530
Indocyanine Green Angiographic Assessment of Conjunctival Melanocytic Disorders.
Palme C, Wanner A, Romano V, Franchi A, Haas G, Kaye SB, Steger B
Cornea 2021 Dec 1;40(12):1519-1524. doi: 10.1097/ICO.0000000000002681. PMID: 33591034
Findings of OCT-angiography compared to fluorescein and indocyanine green angiography in central serous chorioretinopathy.
Min JY, Lv Y, Yu S, Gong YY
Lasers Surg Med 2018 Dec;50(10):987-993. Epub 2018 Jun 12 doi: 10.1002/lsm.22952. PMID: 29896889
Optical Coherence Tomography Angiography of Chorioretinal Diseases.
Novais EA, Roisman L, de Oliveira PR, Louzada RN, Cole ED, Lane M, Filho MB, Romano A, de Oliveira Dias JR, Regatieri CV, Chow D, Belfort R Jr, Rosenfeld P, Waheed NK, Ferrara D, Duker JS
Ophthalmic Surg Lasers Imaging Retina 2016 Sep 1;47(9):848-61. doi: 10.3928/23258160-20160901-09. PMID: 27631482
Dengue-associated maculopathy.
Bacsal KE, Chee SP, Cheng CL, Flores JV
Arch Ophthalmol 2007 Apr;125(4):501-10. doi: 10.1001/archopht.125.4.501. PMID: 17420370

Therapy

Clinical and imaging features of sympathetic ophthalmia and efficacy of the current therapy.
Zhao X, Zhao Q, Meng L, Zhang W, Chen Y
Acta Ophthalmol 2022 Nov;100(7):e1403-e1411. Epub 2022 Jan 27 doi: 10.1111/aos.15095. PMID: 35088530
Multimodal Imaging in the Diagnosis of Exophytic Juxtapapillary Retinal Capillary Hemangioblastoma.
Russell JF, Villegas VM, Schwartz SG, Weng CY, Davis JL, Flynn HW Jr, Harbour JW
Am J Ophthalmol 2021 May;225:128-136. Epub 2021 Jan 12 doi: 10.1016/j.ajo.2021.01.002. PMID: 33450232
OCT Angiography Compared to Fluorescein and Indocyanine Green Angiography in Chronic Central Serous Chorioretinopathy.
Teussink MM, Breukink MB, van Grinsven MJ, Hoyng CB, Klevering BJ, Boon CJ, de Jong EK, Theelen T
Invest Ophthalmol Vis Sci 2015 Aug;56(9):5229-37. doi: 10.1167/iovs.15-17140. PMID: 26244299
Dengue-associated maculopathy.
Bacsal KE, Chee SP, Cheng CL, Flores JV
Arch Ophthalmol 2007 Apr;125(4):501-10. doi: 10.1001/archopht.125.4.501. PMID: 17420370
Principles of treatment of choroidal neovascularization with photodynamic therapy in age-related macular degeneration.
Donati G, Kapetanios AD, Pournaras CJ
Semin Ophthalmol 1999 Mar;14(1):2-10. doi: 10.3109/08820539909056057. PMID: 10790570

Prognosis

Clinical and imaging features of sympathetic ophthalmia and efficacy of the current therapy.
Zhao X, Zhao Q, Meng L, Zhang W, Chen Y
Acta Ophthalmol 2022 Nov;100(7):e1403-e1411. Epub 2022 Jan 27 doi: 10.1111/aos.15095. PMID: 35088530
Indocyanine Green Angiographic Assessment of Conjunctival Melanocytic Disorders.
Palme C, Wanner A, Romano V, Franchi A, Haas G, Kaye SB, Steger B
Cornea 2021 Dec 1;40(12):1519-1524. doi: 10.1097/ICO.0000000000002681. PMID: 33591034
OCT Angiography Compared to Fluorescein and Indocyanine Green Angiography in Chronic Central Serous Chorioretinopathy.
Teussink MM, Breukink MB, van Grinsven MJ, Hoyng CB, Klevering BJ, Boon CJ, de Jong EK, Theelen T
Invest Ophthalmol Vis Sci 2015 Aug;56(9):5229-37. doi: 10.1167/iovs.15-17140. PMID: 26244299
Angiographic leakage of polypoidal choroidal vasculopathy on indocyanine angiography.
Zuo CG, Wen F, Huang SZ, Luo GW, Yan H, Wu WJ, Wu DZ
Chin Med J (Engl) 2010 Jun;123(12):1548-52. PMID: 20819510
Studies on the pathophysiology of diabetic retinopathy. The blood-retinal barrier in diabetes.
Cunha-Vaz JG
Diabetes 1983 May;32 Suppl 2:20-7. doi: 10.2337/diab.32.2.s20. PMID: 6400666

Clinical prediction guides

Imaging Characteristics and Clinical Utility of Half-Dose versus Full-Dose Ultrawidefield Fundus Fluorescein Angiography.
Szigiato A, Sharma S, Singh S, Baynes K, Lowder C, Kaiser PK, Ehlers JP, Srivastava SK
Ophthalmol Retina 2024 Oct;8(10):981-986. Epub 2024 May 6 doi: 10.1016/j.oret.2024.04.024. PMID: 38719190
Indocyanine Green Angiographic Assessment of Conjunctival Melanocytic Disorders.
Palme C, Wanner A, Romano V, Franchi A, Haas G, Kaye SB, Steger B
Cornea 2021 Dec 1;40(12):1519-1524. doi: 10.1097/ICO.0000000000002681. PMID: 33591034
Findings of OCT-angiography compared to fluorescein and indocyanine green angiography in central serous chorioretinopathy.
Min JY, Lv Y, Yu S, Gong YY
Lasers Surg Med 2018 Dec;50(10):987-993. Epub 2018 Jun 12 doi: 10.1002/lsm.22952. PMID: 29896889
OCT Angiography Compared to Fluorescein and Indocyanine Green Angiography in Chronic Central Serous Chorioretinopathy.
Teussink MM, Breukink MB, van Grinsven MJ, Hoyng CB, Klevering BJ, Boon CJ, de Jong EK, Theelen T
Invest Ophthalmol Vis Sci 2015 Aug;56(9):5229-37. doi: 10.1167/iovs.15-17140. PMID: 26244299
Dengue-associated maculopathy.
Bacsal KE, Chee SP, Cheng CL, Flores JV
Arch Ophthalmol 2007 Apr;125(4):501-10. doi: 10.1001/archopht.125.4.501. PMID: 17420370

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...