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Aplastic anemia due to infection

MedGen UID:
124414
•Concept ID:
C0271912
•
Disease or Syndrome
Synonym: Aplastic Anemia due to Infection
SNOMED CT: Aplastic anemia due to infection (191246001)

Definition

Aplastic anemia caused by an infection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAplastic anemia due to infection

Professional guidelines

PubMed

Guidelines for the diagnosis and management of adult aplastic anaemia: A British Society for Haematology Guideline.
Kulasekararaj A, Cavenagh J, Dokal I, Foukaneli T, Gandhi S, Garg M, Griffin M, Hillmen P, Ireland R, Killick S, Mansour S, Mufti G, Potter V, Snowden J, Stanworth S, Zuha R, Marsh J; BSH Committee
Br J Haematol 2024 Mar;204(3):784-804. Epub 2024 Jan 21 doi: 10.1111/bjh.19236. PMID: 38247114
Guidelines for the diagnosis and management of adult aplastic anaemia.
Killick SB, Bown N, Cavenagh J, Dokal I, Foukaneli T, Hill A, Hillmen P, Ireland R, Kulasekararaj A, Mufti G, Snowden JA, Samarasinghe S, Wood A, Marsh JC; British Society for Standards in Haematology
Br J Haematol 2016 Jan;172(2):187-207. Epub 2015 Nov 16 doi: 10.1111/bjh.13853. PMID: 26568159
Hepatitis A: clinical manifestations and management.
Jeong SH, Lee HS
Intervirology 2010;53(1):15-9. Epub 2010 Jan 5 doi: 10.1159/000252779. PMID: 20068336

Recent clinical studies

Etiology

Haploidentical BMT for severe aplastic anemia with intensive GVHD prophylaxis including posttransplant cyclophosphamide.
DeZern AE, Zahurak ML, Symons HJ, Cooke KR, Rosner GL, Gladstone DE, Huff CA, Swinnen LJ, Imus P, Borrello I, Wagner-Johnston N, Ambinder RF, Luznik L, Bolaños-Meade J, Fuchs EJ, Jones RJ, Brodsky RA
Blood Adv 2020 Apr 28;4(8):1770-1779. doi: 10.1182/bloodadvances.2020001729. PMID: 32343796Free PMC Article
Aplastic Anemia Preconditioned with Fludarabine, Cyclophosphamide, and Anti-Thymocyte Globulin.
Yang D, Yang J, Hu X, Chen J, Gao L, Cheng H, Tang G, Luo Y, Zhang W, Wang J
Ann Transplant 2019 Aug 9;24:461-471. doi: 10.12659/AOT.915696. PMID: 31395850Free PMC Article
Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients.
Di Pasquale MF, Sotgiu G, Gramegna A, Radovanovic D, Terraneo S, Reyes LF, Rupp J, González Del Castillo J, Blasi F, Aliberti S, Restrepo MI; GLIMP Investigators
Clin Infect Dis 2019 Apr 24;68(9):1482-1493. doi: 10.1093/cid/ciy723. PMID: 31222287Free PMC Article
Recurrent Polyuria.
Arora N, Durvasula R
Am J Kidney Dis 2018 Nov;72(5):A17-A19. doi: 10.1053/j.ajkd.2018.07.006. PMID: 30343734
Aplastic anaemia: management.
Killick SB, Marsh JC
Blood Rev 2000 Sep;14(3):157-71. doi: 10.1054/blre.2000.0133. PMID: 10986151

Diagnosis

Guidelines for the diagnosis and management of adult aplastic anaemia: A British Society for Haematology Guideline.
Kulasekararaj A, Cavenagh J, Dokal I, Foukaneli T, Gandhi S, Garg M, Griffin M, Hillmen P, Ireland R, Killick S, Mansour S, Mufti G, Potter V, Snowden J, Stanworth S, Zuha R, Marsh J; BSH Committee
Br J Haematol 2024 Mar;204(3):784-804. Epub 2024 Jan 21 doi: 10.1111/bjh.19236. PMID: 38247114
Disseminated Varicella Infection.
Pannu AK, Manikandan G
N Engl J Med 2019 Sep 12;381(11):e21. doi: 10.1056/NEJMicm1814626. PMID: 31509677
Recurrent Polyuria.
Arora N, Durvasula R
Am J Kidney Dis 2018 Nov;72(5):A17-A19. doi: 10.1053/j.ajkd.2018.07.006. PMID: 30343734
Guidelines for the diagnosis and management of adult aplastic anaemia.
Killick SB, Bown N, Cavenagh J, Dokal I, Foukaneli T, Hill A, Hillmen P, Ireland R, Kulasekararaj A, Mufti G, Snowden JA, Samarasinghe S, Wood A, Marsh JC; British Society for Standards in Haematology
Br J Haematol 2016 Jan;172(2):187-207. Epub 2015 Nov 16 doi: 10.1111/bjh.13853. PMID: 26568159
Parvoviruses and bone marrow failure.
Brown KE, Young NS
Stem Cells 1996 Mar;14(2):151-63. doi: 10.1002/stem.140151. PMID: 8991535

Therapy

Clinical outcomes and immune responses to SARS-CoV-2 vaccination in severe aplastic anaemia.
Rajput RV, Ma X, Boswell KL, Gaudinski M, Gordon I, Novik L, Groarke EM, Lotter J, Superata J, Rios OJ, Darden I, Lin BC, Jean-Baptiste N, Carroll R, Moore C, Trost J, Naisan M, Willis J, Serebryannyy L, Wang JL, Prabhakaran M, Narpala SR, Koup RA, McDermott A, Wu CO, Young NS, Patel BA
Br J Haematol 2022 Dec;199(5):679-687. Epub 2022 Sep 21 doi: 10.1111/bjh.18456. PMID: 36128909Free PMC Article
Recurrent Polyuria.
Arora N, Durvasula R
Am J Kidney Dis 2018 Nov;72(5):A17-A19. doi: 10.1053/j.ajkd.2018.07.006. PMID: 30343734
Guidelines for the diagnosis and management of adult aplastic anaemia.
Killick SB, Bown N, Cavenagh J, Dokal I, Foukaneli T, Hill A, Hillmen P, Ireland R, Kulasekararaj A, Mufti G, Snowden JA, Samarasinghe S, Wood A, Marsh JC; British Society for Standards in Haematology
Br J Haematol 2016 Jan;172(2):187-207. Epub 2015 Nov 16 doi: 10.1111/bjh.13853. PMID: 26568159
Hematopoietic growth factors in aplastic anemia patients treated with immunosuppressive therapy-systematic review and meta-analysis.
Gurion R, Gafter-Gvili A, Paul M, Vidal L, Ben-Bassat I, Yeshurun M, Shpilberg O, Raanani P
Haematologica 2009 May;94(5):712-9. Epub 2009 Mar 31 doi: 10.3324/haematol.2008.002170. PMID: 19336743Free PMC Article
Aplastic anaemia: management.
Killick SB, Marsh JC
Blood Rev 2000 Sep;14(3):157-71. doi: 10.1054/blre.2000.0133. PMID: 10986151

Prognosis

Guidelines for the diagnosis and management of adult aplastic anaemia: A British Society for Haematology Guideline.
Kulasekararaj A, Cavenagh J, Dokal I, Foukaneli T, Gandhi S, Garg M, Griffin M, Hillmen P, Ireland R, Killick S, Mansour S, Mufti G, Potter V, Snowden J, Stanworth S, Zuha R, Marsh J; BSH Committee
Br J Haematol 2024 Mar;204(3):784-804. Epub 2024 Jan 21 doi: 10.1111/bjh.19236. PMID: 38247114
Disseminated Varicella Infection.
Pannu AK, Manikandan G
N Engl J Med 2019 Sep 12;381(11):e21. doi: 10.1056/NEJMicm1814626. PMID: 31509677
Recurrent Polyuria.
Arora N, Durvasula R
Am J Kidney Dis 2018 Nov;72(5):A17-A19. doi: 10.1053/j.ajkd.2018.07.006. PMID: 30343734
Neutropenia, agranulocytosis and dipyrone.
Hamerschlak N, Cavalcanti AB
Sao Paulo Med J 2005 Sep 1;123(5):247-9. Epub 2005 Dec 8 doi: 10.1590/s1516-31802005000500009. PMID: 16358101
Aplastic anaemia: management.
Killick SB, Marsh JC
Blood Rev 2000 Sep;14(3):157-71. doi: 10.1054/blre.2000.0133. PMID: 10986151

Clinical prediction guides

Clonal hematopoiesis and associated diseases: A review of recent findings.
Asada S, Kitamura T
Cancer Sci 2021 Oct;112(10):3962-3971. Epub 2021 Aug 12 doi: 10.1111/cas.15094. PMID: 34328684Free PMC Article
Ravulizumab (ALXN1210) vs eculizumab in C5-inhibitor-experienced adult patients with PNH: the 302 study.
Kulasekararaj AG, Hill A, Rottinghaus ST, Langemeijer S, Wells R, Gonzalez-Fernandez FA, Gaya A, Lee JW, Gutierrez EO, Piatek CI, Szer J, Risitano A, Nakao S, Bachman E, Shafner L, Damokosh AI, Ortiz S, Röth A, Peffault de Latour R
Blood 2019 Feb 7;133(6):540-549. Epub 2018 Dec 3 doi: 10.1182/blood-2018-09-876805. PMID: 30510079Free PMC Article
A comprehensive approach to identification of pathogenic FANCA variants in Fanconi anemia patients and their families.
Kimble DC, Lach FP, Gregg SQ, Donovan FX, Flynn EK, Kamat A, Young A, Vemulapalli M, Thomas JW, Mullikin JC, Auerbach AD, Smogorzewska A, Chandrasekharappa SC
Hum Mutat 2018 Feb;39(2):237-254. Epub 2017 Nov 22 doi: 10.1002/humu.23366. PMID: 29098742Free PMC Article
Hepatitis A: clinical manifestations and management.
Jeong SH, Lee HS
Intervirology 2010;53(1):15-9. Epub 2010 Jan 5 doi: 10.1159/000252779. PMID: 20068336
Etanercept in psoriatic arthritis.
Anandarajah AP, Ritchlin CT
Expert Opin Biol Ther 2003 Feb;3(1):169-77. doi: 10.1517/14712598.3.1.169. PMID: 12718739

Recent systematic reviews

Porcine antilymphocyte globulin versus rabbit antithymocyte globulin for intensive immunosuppressive therapy of acquired aplastic anemia: A meta-analysis and systematic review.
Jia J, Wang S, Kang Y, Liu X, Xu L
Int J Clin Pharmacol Ther 2023 Dec;61(12):551-560. doi: 10.5414/CP204379. PMID: 37877292
Post-COVID-19 hematologic complications: a systematic review.
Alahyari S, Moradi M, Rajaeinejad M, Jalaeikhoo H
Expert Rev Hematol 2022 Jun;15(6):539-546. Epub 2022 May 26 doi: 10.1080/17474086.2022.2080051. PMID: 35584541
Invasive fungal sinusitis in the pediatric population: Systematic review with quantitative synthesis of the literature.
Smith A, Thimmappa V, Shepherd B, Ray M, Sheyn A, Thompson J
Int J Pediatr Otorhinolaryngol 2016 Nov;90:231-235. Epub 2016 Sep 17 doi: 10.1016/j.ijporl.2016.09.019. PMID: 27729140
Comparison of a restrictive versus liberal red cell transfusion policy for patients with myelodysplasia, aplastic anaemia, and other congenital bone marrow failure disorders.
Gu Y, Estcourt LJ, Doree C, Hopewell S, Vyas P
Cochrane Database Syst Rev 2015 Oct 5;2015(10):CD011577. doi: 10.1002/14651858.CD011577.pub2. PMID: 26436602Free PMC Article
Hematopoietic growth factors in aplastic anemia patients treated with immunosuppressive therapy-systematic review and meta-analysis.
Gurion R, Gafter-Gvili A, Paul M, Vidal L, Ben-Bassat I, Yeshurun M, Shpilberg O, Raanani P
Haematologica 2009 May;94(5):712-9. Epub 2009 Mar 31 doi: 10.3324/haematol.2008.002170. PMID: 19336743Free PMC Article

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