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Speech disorder

MedGen UID:
11531
•Concept ID:
C0037822
•
Disease or Syndrome
Synonym: Speech Disorders
 
Monarch Initiative: MONDO:0004730

Definition

A term referring to disorders characterized by the disruption of normal speech. It includes stuttering, lisps, dysarthria and voice disorders. [from NCI]

Professional guidelines

PubMed

Speech disorders in Parkinson's disease: pathophysiology, medical management and surgical approaches.
Dashtipour K, Tafreshi A, Lee J, Crawley B
Neurodegener Dis Manag 2018 Oct;8(5):337-348. Epub 2018 Sep 18 doi: 10.2217/nmt-2018-0021. PMID: 30223711
Contemporary Approaches to the Management of Post-stroke Apraxia of Speech.
Basilakos A
Semin Speech Lang 2018 Feb;39(1):25-36. Epub 2018 Jan 22 doi: 10.1055/s-0037-1608853. PMID: 29359303Free PMC Article
Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT): Characteristics, treatment and outcome in 251 cases from the literature.
Laurent C, Capron J, Quillerou B, Thomas G, Alamowitch S, Fain O, Mekinian A
Autoimmun Rev 2016 Dec;15(12):1129-1133. Epub 2016 Sep 15 doi: 10.1016/j.autrev.2016.09.008. PMID: 27639840

Recent clinical studies

Etiology

Infant microbes and metabolites point to childhood neurodevelopmental disorders.
Ahrens AP, Hyötyläinen T, Petrone JR, Igelström K, George CD, Garrett TJ, Orešič M, Triplett EW, Ludvigsson J
Cell 2024 Apr 11;187(8):1853-1873.e15. Epub 2024 Apr 3 doi: 10.1016/j.cell.2024.02.035. PMID: 38574728
Snijders Blok-Campeau Syndrome: Description of 20 Additional Individuals with Variants in CHD3 and Literature Review.
Pascual P, Tenorio-Castano J, Mignot C, Afenjar A, Arias P, Gallego-Zazo N, Parra A, Miranda L, Cazalla M, Silván C, Heron D, Keren B, Popa I, Palomares M, Rikeros E, Ramos FJ, Almoguera B, Ayuso C, Swafiri ST, Barbero AIS, Srinivasan VM, Gowda VK, Morleo M, Nigro V, D'Arrigo S, Ciaccio C, Martin Mesa C, Paumard B, Guillen G, Anton ATS, Jimenez MD, Seidel V, Suárez J, Cormier-Daire V, Consortium TS, Nevado J, Lapunzina P
Genes (Basel) 2023 Aug 23;14(9) doi: 10.3390/genes14091664. PMID: 37761804Free PMC Article
Cerebellar mutism syndrome.
Catsman-Berrevoets C, Patay Z
Handb Clin Neurol 2018;155:273-288. doi: 10.1016/B978-0-444-64189-2.00018-4. PMID: 29891065
Consensus Paper: Revisiting the Symptoms and Signs of Cerebellar Syndrome.
Bodranghien F, Bastian A, Casali C, Hallett M, Louis ED, Manto M, Mariën P, Nowak DA, Schmahmann JD, Serrao M, Steiner KM, Strupp M, Tilikete C, Timmann D, van Dun K
Cerebellum 2016 Jun;15(3):369-91. doi: 10.1007/s12311-015-0687-3. PMID: 26105056Free PMC Article
Disorders of communication: dysarthria.
Enderby P
Handb Clin Neurol 2013;110:273-81. doi: 10.1016/B978-0-444-52901-5.00022-8. PMID: 23312647

Diagnosis

Infant microbes and metabolites point to childhood neurodevelopmental disorders.
Ahrens AP, Hyötyläinen T, Petrone JR, Igelström K, George CD, Garrett TJ, Orešič M, Triplett EW, Ludvigsson J
Cell 2024 Apr 11;187(8):1853-1873.e15. Epub 2024 Apr 3 doi: 10.1016/j.cell.2024.02.035. PMID: 38574728
An Update on Apraxia of Speech.
Utianski RL, Josephs KA
Curr Neurol Neurosci Rep 2023 Jul;23(7):353-359. Epub 2023 Jun 3 doi: 10.1007/s11910-023-01275-1. PMID: 37269450Free PMC Article
Primary Progressive Aphasias and Apraxia of Speech.
Botha H, Josephs KA
Continuum (Minneap Minn) 2019 Feb;25(1):101-127. doi: 10.1212/CON.0000000000000699. PMID: 30707189Free PMC Article
Stuttering: Clinical and research update.
Perez HR, Stoeckle JH
Can Fam Physician 2016 Jun;62(6):479-84. PMID: 27303004Free PMC Article
Disorders of communication: dysarthria.
Enderby P
Handb Clin Neurol 2013;110:273-81. doi: 10.1016/B978-0-444-52901-5.00022-8. PMID: 23312647

Therapy

The effect of ankyloglossia and tongue-tie division on speech articulation: A systematic review.
Wang J, Yang X, Hao S, Wang Y
Int J Paediatr Dent 2022 Mar;32(2):144-156. Epub 2021 May 22 doi: 10.1111/ipd.12802. PMID: 33964037
Cerebellar mutism syndrome.
Catsman-Berrevoets C, Patay Z
Handb Clin Neurol 2018;155:273-288. doi: 10.1016/B978-0-444-64189-2.00018-4. PMID: 29891065
Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT): Characteristics, treatment and outcome in 251 cases from the literature.
Laurent C, Capron J, Quillerou B, Thomas G, Alamowitch S, Fain O, Mekinian A
Autoimmun Rev 2016 Dec;15(12):1129-1133. Epub 2016 Sep 15 doi: 10.1016/j.autrev.2016.09.008. PMID: 27639840
Stuttering: Clinical and research update.
Perez HR, Stoeckle JH
Can Fam Physician 2016 Jun;62(6):479-84. PMID: 27303004Free PMC Article
Treatment for speech disorder in Friedreich ataxia and other hereditary ataxia syndromes.
Vogel AP, Folker J, Poole ML
Cochrane Database Syst Rev 2014 Oct 28;2014(10):CD008953. doi: 10.1002/14651858.CD008953.pub2. PMID: 25348587Free PMC Article

Prognosis

Infant microbes and metabolites point to childhood neurodevelopmental disorders.
Ahrens AP, Hyötyläinen T, Petrone JR, Igelström K, George CD, Garrett TJ, Orešič M, Triplett EW, Ludvigsson J
Cell 2024 Apr 11;187(8):1853-1873.e15. Epub 2024 Apr 3 doi: 10.1016/j.cell.2024.02.035. PMID: 38574728
Snijders Blok-Campeau Syndrome: Description of 20 Additional Individuals with Variants in CHD3 and Literature Review.
Pascual P, Tenorio-Castano J, Mignot C, Afenjar A, Arias P, Gallego-Zazo N, Parra A, Miranda L, Cazalla M, Silván C, Heron D, Keren B, Popa I, Palomares M, Rikeros E, Ramos FJ, Almoguera B, Ayuso C, Swafiri ST, Barbero AIS, Srinivasan VM, Gowda VK, Morleo M, Nigro V, D'Arrigo S, Ciaccio C, Martin Mesa C, Paumard B, Guillen G, Anton ATS, Jimenez MD, Seidel V, Suárez J, Cormier-Daire V, Consortium TS, Nevado J, Lapunzina P
Genes (Basel) 2023 Aug 23;14(9) doi: 10.3390/genes14091664. PMID: 37761804Free PMC Article
Speech and language therapy: A treatment case series of 20 patients with functional speech disorder.
Goldstein AN, Paredes-Echeverri S, Finkelstein SA, Guthrie AJ, Perez DL, Freeburn JL
NeuroRehabilitation 2023;53(2):227-238. doi: 10.3233/NRE-220182. PMID: 37599546
Primary Progressive Aphasias and Apraxia of Speech.
Botha H, Josephs KA
Continuum (Minneap Minn) 2019 Feb;25(1):101-127. doi: 10.1212/CON.0000000000000699. PMID: 30707189Free PMC Article
What causes stuttering?
Büchel C, Sommer M
PLoS Biol 2004 Feb;2(2):E46. Epub 2004 Feb 17 doi: 10.1371/journal.pbio.0020046. PMID: 14966540Free PMC Article

Clinical prediction guides

GLUT1DS focus on dysarthria.
Corradini M, Zanaboni MP, Varesio C, Celario M, Capelli E, Giudice C, Quaranta CA, Mensi MM, Pasca L, De Giorgis V
Eur J Paediatr Neurol 2024 Jul;51:62-70. Epub 2024 May 29 doi: 10.1016/j.ejpn.2024.05.010. PMID: 38851145
Infant microbes and metabolites point to childhood neurodevelopmental disorders.
Ahrens AP, Hyötyläinen T, Petrone JR, Igelström K, George CD, Garrett TJ, Orešič M, Triplett EW, Ludvigsson J
Cell 2024 Apr 11;187(8):1853-1873.e15. Epub 2024 Apr 3 doi: 10.1016/j.cell.2024.02.035. PMID: 38574728
Snijders Blok-Campeau Syndrome: Description of 20 Additional Individuals with Variants in CHD3 and Literature Review.
Pascual P, Tenorio-Castano J, Mignot C, Afenjar A, Arias P, Gallego-Zazo N, Parra A, Miranda L, Cazalla M, Silván C, Heron D, Keren B, Popa I, Palomares M, Rikeros E, Ramos FJ, Almoguera B, Ayuso C, Swafiri ST, Barbero AIS, Srinivasan VM, Gowda VK, Morleo M, Nigro V, D'Arrigo S, Ciaccio C, Martin Mesa C, Paumard B, Guillen G, Anton ATS, Jimenez MD, Seidel V, Suárez J, Cormier-Daire V, Consortium TS, Nevado J, Lapunzina P
Genes (Basel) 2023 Aug 23;14(9) doi: 10.3390/genes14091664. PMID: 37761804Free PMC Article
The effect of ankyloglossia and tongue-tie division on speech articulation: A systematic review.
Wang J, Yang X, Hao S, Wang Y
Int J Paediatr Dent 2022 Mar;32(2):144-156. Epub 2021 May 22 doi: 10.1111/ipd.12802. PMID: 33964037
Consensus Paper: Revisiting the Symptoms and Signs of Cerebellar Syndrome.
Bodranghien F, Bastian A, Casali C, Hallett M, Louis ED, Manto M, Mariën P, Nowak DA, Schmahmann JD, Serrao M, Steiner KM, Strupp M, Tilikete C, Timmann D, van Dun K
Cerebellum 2016 Jun;15(3):369-91. doi: 10.1007/s12311-015-0687-3. PMID: 26105056Free PMC Article

Recent systematic reviews

The effect of ankyloglossia and tongue-tie division on speech articulation: A systematic review.
Wang J, Yang X, Hao S, Wang Y
Int J Paediatr Dent 2022 Mar;32(2):144-156. Epub 2021 May 22 doi: 10.1111/ipd.12802. PMID: 33964037
The Relationship between Feeding and Non-Nutritive Sucking Behaviours and Speech Sound Development: A Systematic Review.
Burr S, Harding S, Wren Y, Deave T
Folia Phoniatr Logop 2021;73(2):75-88. Epub 2020 Feb 10 doi: 10.1159/000505266. PMID: 32040950
Speech and language in bilateral perisylvian polymicrogyria: a systematic review.
Braden RO, Leventer RJ, Jansen A, Scheffer IE, Morgan AT
Dev Med Child Neurol 2019 Oct;61(10):1145-1152. Epub 2019 Jan 25 doi: 10.1111/dmcn.14153. PMID: 30680716
Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT): Characteristics, treatment and outcome in 251 cases from the literature.
Laurent C, Capron J, Quillerou B, Thomas G, Alamowitch S, Fain O, Mekinian A
Autoimmun Rev 2016 Dec;15(12):1129-1133. Epub 2016 Sep 15 doi: 10.1016/j.autrev.2016.09.008. PMID: 27639840
Treatment for speech disorder in Friedreich ataxia and other hereditary ataxia syndromes.
Vogel AP, Folker J, Poole ML
Cochrane Database Syst Rev 2014 Oct 28;2014(10):CD008953. doi: 10.1002/14651858.CD008953.pub2. PMID: 25348587Free PMC Article

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