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Local anesthetic ineffectiveness

MedGen UID:
1054282
•Concept ID:
CN378456
•
Finding
HPO: HP:6001108

Definition

Resistance to the effects of local anaesthesia, with delayed onset or failure of local anesthetics to incude numbness or relieve pain. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocal anesthetic ineffectiveness

Professional guidelines

PubMed

Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review.
Coppola N, Cantile T, Adamo D, Canfora F, Baldares S, Riccitiello F, Musella G, Mignogna MDD, Leuci S
Clin Oral Investig 2023 Nov;27(11):6333-6344. Epub 2023 Sep 21 doi: 10.1007/s00784-023-05250-5. PMID: 37733027Free PMC Article
Microwave Treatment for Axillary Hyperhidrosis and Bromhidrosis.
Sánchez-Carpintero I, Martín-Gorgojo A, Ruiz-Rodríguez R
Actas Dermosifiliogr 2017 Jun;108(5):418-422. Epub 2017 Mar 9 doi: 10.1016/j.ad.2016.12.011. PMID: 28284421
Treatment of neonatal seizures.
van Rooij LG, Hellström-Westas L, de Vries LS
Semin Fetal Neonatal Med 2013 Aug;18(4):209-15. Epub 2013 Feb 9 doi: 10.1016/j.siny.2013.01.001. PMID: 23402893

Recent clinical studies

Etiology

Effects of transcranial magnetic stimulation on cocaine addiction: A systematic review of randomized controlled trials.
Amerio A, Baccino C, Breda GS, Cortesi D, Spiezio V, Magnani L, De Berardis D, Conio B, Costanza A, De Paola G, Rocca G, Arduino G, Aguglia A, Amore M, Serafini G
Psychiatry Res 2023 Nov;329:115491. Epub 2023 Sep 22 doi: 10.1016/j.psychres.2023.115491. PMID: 37783092
Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review.
Coppola N, Cantile T, Adamo D, Canfora F, Baldares S, Riccitiello F, Musella G, Mignogna MDD, Leuci S
Clin Oral Investig 2023 Nov;27(11):6333-6344. Epub 2023 Sep 21 doi: 10.1007/s00784-023-05250-5. PMID: 37733027Free PMC Article
Microwave Treatment for Axillary Hyperhidrosis and Bromhidrosis.
Sánchez-Carpintero I, Martín-Gorgojo A, Ruiz-Rodríguez R
Actas Dermosifiliogr 2017 Jun;108(5):418-422. Epub 2017 Mar 9 doi: 10.1016/j.ad.2016.12.011. PMID: 28284421
Paravertebral block versus thoracic epidural for patients undergoing thoracotomy.
Yeung JH, Gates S, Naidu BV, Wilson MJ, Gao Smith F
Cochrane Database Syst Rev 2016 Feb 21;2(2):CD009121. doi: 10.1002/14651858.CD009121.pub2. PMID: 26897642Free PMC Article
Interventions for pain with intrauterine device insertion.
Lopez LM, Bernholc A, Zeng Y, Allen RH, Bartz D, O'Brien PA, Hubacher D
Cochrane Database Syst Rev 2015 Jul 29;2015(7):CD007373. doi: 10.1002/14651858.CD007373.pub3. PMID: 26222246Free PMC Article

Diagnosis

Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review.
Coppola N, Cantile T, Adamo D, Canfora F, Baldares S, Riccitiello F, Musella G, Mignogna MDD, Leuci S
Clin Oral Investig 2023 Nov;27(11):6333-6344. Epub 2023 Sep 21 doi: 10.1007/s00784-023-05250-5. PMID: 37733027Free PMC Article
The treatment of chronic recurrent oral aphthous ulcers.
Altenburg A, El-Haj N, Micheli C, Puttkammer M, Abdel-Naser MB, Zouboulis CC
Dtsch Arztebl Int 2014 Oct 3;111(40):665-73. doi: 10.3238/arztebl.2014.0665. PMID: 25346356Free PMC Article
Treatment of neonatal seizures.
van Rooij LG, Hellström-Westas L, de Vries LS
Semin Fetal Neonatal Med 2013 Aug;18(4):209-15. Epub 2013 Feb 9 doi: 10.1016/j.siny.2013.01.001. PMID: 23402893
"Fibrositis" syndrome.
Rice JR
Med Clin North Am 1986 Mar;70(2):455-68. doi: 10.1016/s0025-7125(16)30963-4. PMID: 3512933
The Fabella Syndrome.
Weiner D, Macnab I, Turner M
Clin Orthop Relat Res 1977 Jul-Aug;(126):213-5. PMID: 598120

Therapy

Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review.
Coppola N, Cantile T, Adamo D, Canfora F, Baldares S, Riccitiello F, Musella G, Mignogna MDD, Leuci S
Clin Oral Investig 2023 Nov;27(11):6333-6344. Epub 2023 Sep 21 doi: 10.1007/s00784-023-05250-5. PMID: 37733027Free PMC Article
Pharmacological and clinical implications of local anaesthetic mixtures: a narrative review.
Nestor CC, Ng C, Sepulveda P, Irwin MG
Anaesthesia 2022 Mar;77(3):339-350. Epub 2021 Dec 14 doi: 10.1111/anae.15641. PMID: 34904711
Paravertebral block versus thoracic epidural for patients undergoing thoracotomy.
Yeung JH, Gates S, Naidu BV, Wilson MJ, Gao Smith F
Cochrane Database Syst Rev 2016 Feb 21;2(2):CD009121. doi: 10.1002/14651858.CD009121.pub2. PMID: 26897642Free PMC Article
Interventions for pain with intrauterine device insertion.
Lopez LM, Bernholc A, Zeng Y, Allen RH, Bartz D, O'Brien PA, Hubacher D
Cochrane Database Syst Rev 2015 Jul 29;2015(7):CD007373. doi: 10.1002/14651858.CD007373.pub3. PMID: 26222246Free PMC Article
"Fibrositis" syndrome.
Rice JR
Med Clin North Am 1986 Mar;70(2):455-68. doi: 10.1016/s0025-7125(16)30963-4. PMID: 3512933

Prognosis

Different interventions in preventing opioid-induced cough: a meta-analysis.
Shuying L, Ping L, Juan N, Dong L
J Clin Anesth 2016 Nov;34:440-7. Epub 2016 Jun 17 doi: 10.1016/j.jclinane.2016.05.034. PMID: 27687431
The treatment of chronic recurrent oral aphthous ulcers.
Altenburg A, El-Haj N, Micheli C, Puttkammer M, Abdel-Naser MB, Zouboulis CC
Dtsch Arztebl Int 2014 Oct 3;111(40):665-73. doi: 10.3238/arztebl.2014.0665. PMID: 25346356Free PMC Article
Occipital nerve blocks: when and what to inject?
Tobin J, Flitman S
Headache 2009 Nov-Dec;49(10):1521-33. Epub 2009 Aug 6 doi: 10.1111/j.1526-4610.2009.01493.x. PMID: 19674126
Whiplash: pathophysiology, diagnosis, treatment, and prognosis.
Rodriquez AA, Barr KP, Burns SP
Muscle Nerve 2004 Jun;29(6):768-81. doi: 10.1002/mus.20060. PMID: 15170609
"Fibrositis" syndrome.
Rice JR
Med Clin North Am 1986 Mar;70(2):455-68. doi: 10.1016/s0025-7125(16)30963-4. PMID: 3512933

Clinical prediction guides

Effects of transcranial magnetic stimulation on cocaine addiction: A systematic review of randomized controlled trials.
Amerio A, Baccino C, Breda GS, Cortesi D, Spiezio V, Magnani L, De Berardis D, Conio B, Costanza A, De Paola G, Rocca G, Arduino G, Aguglia A, Amore M, Serafini G
Psychiatry Res 2023 Nov;329:115491. Epub 2023 Sep 22 doi: 10.1016/j.psychres.2023.115491. PMID: 37783092
Effect of Honey on Cough Symptoms in Children with Upper Respiratory Tract Infection: A Randomised Controlled Trial.
Anibasa FO, Abuba T, Dankyau M
West Afr J Med 2022 Sep 16;39(9):928-934. PMID: 36126325
Interventions for pain with intrauterine device insertion.
Lopez LM, Bernholc A, Zeng Y, Allen RH, Bartz D, O'Brien PA, Hubacher D
Cochrane Database Syst Rev 2015 Jul 29;2015(7):CD007373. doi: 10.1002/14651858.CD007373.pub3. PMID: 26222246Free PMC Article
Occipital nerve blocks: when and what to inject?
Tobin J, Flitman S
Headache 2009 Nov-Dec;49(10):1521-33. Epub 2009 Aug 6 doi: 10.1111/j.1526-4610.2009.01493.x. PMID: 19674126
"Fibrositis" syndrome.
Rice JR
Med Clin North Am 1986 Mar;70(2):455-68. doi: 10.1016/s0025-7125(16)30963-4. PMID: 3512933

Recent systematic reviews

Effects of transcranial magnetic stimulation on cocaine addiction: A systematic review of randomized controlled trials.
Amerio A, Baccino C, Breda GS, Cortesi D, Spiezio V, Magnani L, De Berardis D, Conio B, Costanza A, De Paola G, Rocca G, Arduino G, Aguglia A, Amore M, Serafini G
Psychiatry Res 2023 Nov;329:115491. Epub 2023 Sep 22 doi: 10.1016/j.psychres.2023.115491. PMID: 37783092
Supportive care and antiviral treatments in primary herpetic gingivostomatitis: a systematic review.
Coppola N, Cantile T, Adamo D, Canfora F, Baldares S, Riccitiello F, Musella G, Mignogna MDD, Leuci S
Clin Oral Investig 2023 Nov;27(11):6333-6344. Epub 2023 Sep 21 doi: 10.1007/s00784-023-05250-5. PMID: 37733027Free PMC Article
Comparison of different delivery modalities of epidural analgesia and intravenous analgesia in labour: a systematic review and network meta-analysis.
Wydall S, Zolger D, Owolabi A, Nzekwu B, Onwochei D, Desai N
Can J Anaesth 2023 Mar;70(3):406-442. Epub 2023 Jan 31 doi: 10.1007/s12630-022-02389-9. PMID: 36720838
Paravertebral block versus thoracic epidural for patients undergoing thoracotomy.
Yeung JH, Gates S, Naidu BV, Wilson MJ, Gao Smith F
Cochrane Database Syst Rev 2016 Feb 21;2(2):CD009121. doi: 10.1002/14651858.CD009121.pub2. PMID: 26897642Free PMC Article
Interventions for pain with intrauterine device insertion.
Lopez LM, Bernholc A, Zeng Y, Allen RH, Bartz D, O'Brien PA, Hubacher D
Cochrane Database Syst Rev 2015 Jul 29;2015(7):CD007373. doi: 10.1002/14651858.CD007373.pub3. PMID: 26222246Free PMC Article

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