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Estrogen-receptor negative breast cancer

MedGen UID:
1054040
•Concept ID:
CN377663
•
Disease or Syndrome
Synonyms: ER- breast cancer; estrogen-receptor negative breast cancer
 
Monarch Initiative: MONDO:0006513

Definition

A subtype of breast cancer that is estrogen-receptor negative [from MONDO]

Professional guidelines

PubMed

Interaction of green tea catechins with breast cancer endocrine treatment: a systematic review.
Yiannakopoulou EC
Pharmacology 2014;94(5-6):245-8. Epub 2014 Nov 28 doi: 10.1159/000369170. PMID: 25471334
Cannabinoids in the treatment of cancer.
Alexander A, Smith PF, Rosengren RJ
Cancer Lett 2009 Nov 18;285(1):6-12. Epub 2009 May 12 doi: 10.1016/j.canlet.2009.04.005. PMID: 19442435
Economic evaluation of the prevention and treatment of breast cancer--present status and open issues.
Imai H, Kuroi K, Ohsumi S, Ono M, Shimozuma K
Breast Cancer 2007;14(1):81-7. doi: 10.2325/jbcs.14.81. PMID: 17245000

Recent clinical studies

Therapy

Elucidating the relationship between breast cancer and brain cortical structure: a Mendelian randomization study.
Lin Y, Wang S, Zhang L, Yang Q
Cereb Cortex 2024 Jan 14;34(1) doi: 10.1093/cercor/bhad498. PMID: 38112592
The association between thyroid and breast cancers: a bidirectional mendelian randomization study.
Liu J, Liang L
Front Endocrinol (Lausanne) 2023;14:1185497. Epub 2023 Oct 25 doi: 10.3389/fendo.2023.1185497. PMID: 37955011Free PMC Article
Causal relationships between serum matrix metalloproteinases and estrogen receptor-negative breast cancer: a bidirectional mendelian randomization study.
Zhao Z, Cao Q, Zhu M, Wang C, Lu X
Sci Rep 2023 May 15;13(1):7849. doi: 10.1038/s41598-023-34200-0. PMID: 37188722Free PMC Article
Associations of genetically proxied inhibition of HMG-CoA reductase, NPC1L1, and PCSK9 with breast cancer and prostate cancer.
Sun L, Ding H, Jia Y, Shi M, Guo D, Yang P, Wang Y, Liu F, Zhang Y, Zhu Z
Breast Cancer Res 2022 Feb 12;24(1):12. doi: 10.1186/s13058-022-01508-0. PMID: 35151363Free PMC Article
Metformin and Chemoprevention: Potential for Heart-Healthy Targeting of Biologically Aggressive Breast Cancer.
Jones VC, Dietze EC, Jovanovic-Talisman T, McCune JS, Seewaldt VL
Front Public Health 2020;8:509714. Epub 2020 Oct 29 doi: 10.3389/fpubh.2020.509714. PMID: 33194937Free PMC Article

Prognosis

Radiosensitivity is associated with antitumor immunity in estrogen receptor-negative breast cancer.
Kang BH, Jang BS, Kim IA
Breast Cancer Res Treat 2023 Feb;197(3):479-488. Epub 2022 Dec 14 doi: 10.1007/s10549-022-06818-7. PMID: 36515748
Metformin and Chemoprevention: Potential for Heart-Healthy Targeting of Biologically Aggressive Breast Cancer.
Jones VC, Dietze EC, Jovanovic-Talisman T, McCune JS, Seewaldt VL
Front Public Health 2020;8:509714. Epub 2020 Oct 29 doi: 10.3389/fpubh.2020.509714. PMID: 33194937Free PMC Article
Aspirin and NSAIDs for breast cancer chemoprevention.
Yiannakopoulou ECh
Eur J Cancer Prev 2015 Sep;24(5):416-21. doi: 10.1097/CEJ.0000000000000098. PMID: 25380191
Does microenvironment contribute to the etiology of estrogen receptor-negative breast cancer?
Barcellos-Hoff MH
Clin Cancer Res 2013 Feb 1;19(3):541-8. Epub 2013 Jan 16 doi: 10.1158/1078-0432.CCR-12-2241. PMID: 23325583
Estrogen receptors and breast cancer.
Stanford JL, Szklo M, Brinton LA
Epidemiol Rev 1986;8:42-59. doi: 10.1093/oxfordjournals.epirev.a036295. PMID: 3533584

Clinical prediction guides

Elucidating the relationship between breast cancer and brain cortical structure: a Mendelian randomization study.
Lin Y, Wang S, Zhang L, Yang Q
Cereb Cortex 2024 Jan 14;34(1) doi: 10.1093/cercor/bhad498. PMID: 38112592
The association between thyroid and breast cancers: a bidirectional mendelian randomization study.
Liu J, Liang L
Front Endocrinol (Lausanne) 2023;14:1185497. Epub 2023 Oct 25 doi: 10.3389/fendo.2023.1185497. PMID: 37955011Free PMC Article
Metformin and Chemoprevention: Potential for Heart-Healthy Targeting of Biologically Aggressive Breast Cancer.
Jones VC, Dietze EC, Jovanovic-Talisman T, McCune JS, Seewaldt VL
Front Public Health 2020;8:509714. Epub 2020 Oct 29 doi: 10.3389/fpubh.2020.509714. PMID: 33194937Free PMC Article
Associations between Diet Quality Scores and Risk of Postmenopausal Estrogen Receptor-Negative Breast Cancer: A Systematic Review.
Du M, Liu SH, Mitchell C, Fung TT
J Nutr 2018 Jan 1;148(1):100-108. doi: 10.1093/jn/nxx015. PMID: 29378048
Estrogen receptors and breast cancer.
Stanford JL, Szklo M, Brinton LA
Epidemiol Rev 1986;8:42-59. doi: 10.1093/oxfordjournals.epirev.a036295. PMID: 3533584

Recent systematic reviews

Survival and clinicopathological significance of blood vessel invasion in operable breast cancer: a systematic review and meta-analysis.
Lin Y, Zhang Y, Fang H, Hu Q, Duan H, Zhang L, Pang D
Jpn J Clin Oncol 2023 Jan 6;53(1):35-45. doi: 10.1093/jjco/hyac149. PMID: 36156086
Associations between Diet Quality Scores and Risk of Postmenopausal Estrogen Receptor-Negative Breast Cancer: A Systematic Review.
Du M, Liu SH, Mitchell C, Fung TT
J Nutr 2018 Jan 1;148(1):100-108. doi: 10.1093/jn/nxx015. PMID: 29378048
Long-Term Sleep Duration as a Risk Factor for Breast Cancer: Evidence from a Systematic Review and Dose-Response Meta-Analysis.
Lu C, Sun H, Huang J, Yin S, Hou W, Zhang J, Wang Y, Xu Y, Xu H
Biomed Res Int 2017;2017:4845059. Epub 2017 Oct 10 doi: 10.1155/2017/4845059. PMID: 29130041Free PMC Article
Interaction of green tea catechins with breast cancer endocrine treatment: a systematic review.
Yiannakopoulou EC
Pharmacology 2014;94(5-6):245-8. Epub 2014 Nov 28 doi: 10.1159/000369170. PMID: 25471334
Systematic review: comparative effectiveness of medications to reduce risk for primary breast cancer.
Nelson HD, Fu R, Griffin JC, Nygren P, Smith ME, Humphrey L
Ann Intern Med 2009 Nov 17;151(10):703-15, W-226-35. doi: 10.7326/0003-4819-151-10-200911170-00147. PMID: 19920271

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