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Antisperm antibody positivity

MedGen UID:
1053758
Concept ID:
CN376701
Finding
HPO: HP:6000188

Definition

The presence of autoantibodies (immunoglobulins) in the serum that react against sperm antigens. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAntisperm antibody positivity

Professional guidelines

PubMed

Krapez JA, Hayden CJ, Rutherford AJ, Balen AH
Hum Reprod 1998 Dec;13(12):3363-7. doi: 10.1093/humrep/13.12.3363. PMID: 9886515
Nagy ZP, Verheyen G, Liu J, Joris H, Janssenswillen C, Wisanto A, Devroey P, Van Steirteghem AC
Hum Reprod 1995 Jul;10(7):1775-80. doi: 10.1093/oxfordjournals.humrep.a136172. PMID: 8582978
Vazquez-Levin MH, Kupchik GS, Torres Y, Chaparro CA, Shtainer A, Bonforte RJ, Nagler HM
J Reprod Immunol 1994 Dec;27(3):199-212. doi: 10.1016/0165-0378(94)90004-3. PMID: 7738909

Recent clinical studies

Etiology

Negri L, Romano M, Cirillo F, Grilli L, Morenghi E, Romualdi D, Albani E, Setti PEL
Andrology 2022 Jan;10(1):105-110. Epub 2021 Aug 6 doi: 10.1111/andr.13084. PMID: 34331520
Cuppett VA, Sikka SC, Naz RK
Front Biosci (Elite Ed) 2017 Mar 1;9(2):258-265. doi: 10.2741/e800. PMID: 28199189
Cui D, Han G, Shang Y, Liu C, Xia L, Li L, Yi S
Clin Chim Acta 2015 Apr 15;444:29-36. Epub 2015 Feb 7 doi: 10.1016/j.cca.2015.01.033. PMID: 25659295
Zini A, Fahmy N, Belzile E, Ciampi A, Al-Hathal N, Kotb A
Hum Reprod 2011 Jun;26(6):1288-95. Epub 2011 Mar 23 doi: 10.1093/humrep/der074. PMID: 21429953
Szczepañska M, Skrzypczak J, Kamieniczna M, Kurpisz M
Fertil Steril 2001 Jan;75(1):97-105. doi: 10.1016/s0015-0282(00)01667-8. PMID: 11163823

Diagnosis

Negri L, Romano M, Cirillo F, Grilli L, Morenghi E, Romualdi D, Albani E, Setti PEL
Andrology 2022 Jan;10(1):105-110. Epub 2021 Aug 6 doi: 10.1111/andr.13084. PMID: 34331520
Szczepañska M, Skrzypczak J, Kamieniczna M, Kurpisz M
Fertil Steril 2001 Jan;75(1):97-105. doi: 10.1016/s0015-0282(00)01667-8. PMID: 11163823
Sinisi AA, Pasquali D, Papparella A, Valente A, Orio F, Esposito D, Cobellis G, Cuomo A, Angelone G, Martone A, Fioretti GP, Bellastella A
J Urol 1998 Nov;160(5):1834-7. PMID: 9783970
Haas GG Jr
Obstet Gynecol Clin North Am 1987 Dec;14(4):1069-85. PMID: 3328124
Troen P, Oshima H
N Engl J Med 1980 Sep 25;303(13):751-2. doi: 10.1056/NEJM198009253031309. PMID: 7402272

Therapy

Negri L, Romano M, Cirillo F, Grilli L, Morenghi E, Romualdi D, Albani E, Setti PEL
Andrology 2022 Jan;10(1):105-110. Epub 2021 Aug 6 doi: 10.1111/andr.13084. PMID: 34331520
Jiang Y, Cui D, Du Y, Lu J, Yang L, Li J, Zhang J, Bai X
J Reprod Immunol 2016 Nov;118:85-91. Epub 2016 Sep 30 doi: 10.1016/j.jri.2016.09.004. PMID: 27743525
Cui D, Han G, Shang Y, Liu C, Xia L, Li L, Yi S
Clin Chim Acta 2015 Apr 15;444:29-36. Epub 2015 Feb 7 doi: 10.1016/j.cca.2015.01.033. PMID: 25659295
Szczepañska M, Skrzypczak J, Kamieniczna M, Kurpisz M
Fertil Steril 2001 Jan;75(1):97-105. doi: 10.1016/s0015-0282(00)01667-8. PMID: 11163823
Kovacs GT, Frances M
Med J Aust 1983 Nov 26;2(11):564-7. doi: 10.5694/j.1326-5377.1983.tb122678.x. PMID: 6633392

Prognosis

Negri L, Romano M, Cirillo F, Grilli L, Morenghi E, Romualdi D, Albani E, Setti PEL
Andrology 2022 Jan;10(1):105-110. Epub 2021 Aug 6 doi: 10.1111/andr.13084. PMID: 34331520
Djaladat H, Mehrsai A, Rezazade M, Djaladat Y, Pourmand G
South Med J 2006 Jan;99(1):44-7. doi: 10.1097/01.smj.0000197036.08282.70. PMID: 16466121
Szczepañska M, Skrzypczak J, Kamieniczna M, Kurpisz M
Fertil Steril 2001 Jan;75(1):97-105. doi: 10.1016/s0015-0282(00)01667-8. PMID: 11163823
Culligan PJ, Crane MM, Boone WR, Allen TC, Price TM, Blauer KL
Fertil Steril 1998 May;69(5):894-8. doi: 10.1016/s0015-0282(98)00034-x. PMID: 9591499
Bahraminejad R, Kadanali S, Erten O, Bahar H
Acta Obstet Gynecol Scand 1991;70(6):483-5. doi: 10.3109/00016349109007164. PMID: 1763614

Clinical prediction guides

Kiani A, Döğüş Y, Saadatnia S, Yazdani Y, Asadi F, Al-Naqeeb BZT, Masouleh SS, Merza MS, Daemi A, Rahimi A
Pathol Res Pract 2023 May;245:154434. Epub 2023 Apr 1 doi: 10.1016/j.prp.2023.154434. PMID: 37086632
Garolla A, Pizzol D, Bertoldo A, De Toni L, Barzon L, Foresta C
Fertil Steril 2013 Jan;99(1):125-131.e2. Epub 2012 Oct 6 doi: 10.1016/j.fertnstert.2012.09.006. PMID: 23043686
Leushuis E, van der Steeg JW, Steures P, Repping S, Schöls W, van der Veen F, Mol BW, Hompes PG
Fertil Steril 2009 Nov;92(5):1659-65. Epub 2008 Oct 31 doi: 10.1016/j.fertnstert.2008.08.082. PMID: 18976763
Szczepañska M, Skrzypczak J, Kamieniczna M, Kurpisz M
Fertil Steril 2001 Jan;75(1):97-105. doi: 10.1016/s0015-0282(00)01667-8. PMID: 11163823
Sinisi AA, Pasquali D, Papparella A, Valente A, Orio F, Esposito D, Cobellis G, Cuomo A, Angelone G, Martone A, Fioretti GP, Bellastella A
J Urol 1998 Nov;160(5):1834-7. PMID: 9783970

Recent systematic reviews

Jiang Y, Cui D, Du Y, Lu J, Yang L, Li J, Zhang J, Bai X
J Reprod Immunol 2016 Nov;118:85-91. Epub 2016 Sep 30 doi: 10.1016/j.jri.2016.09.004. PMID: 27743525
Cui D, Han G, Shang Y, Liu C, Xia L, Li L, Yi S
Clin Chim Acta 2015 Apr 15;444:29-36. Epub 2015 Feb 7 doi: 10.1016/j.cca.2015.01.033. PMID: 25659295
Zini A, Fahmy N, Belzile E, Ciampi A, Al-Hathal N, Kotb A
Hum Reprod 2011 Jun;26(6):1288-95. Epub 2011 Mar 23 doi: 10.1093/humrep/der074. PMID: 21429953

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