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Adrenal medulla carcinoma

MedGen UID:
1053627
•Concept ID:
CN377718
•
Disease or Syndrome
Synonyms: adrenal medulla carcinoma; carcinoma of adrenal medulla
 
Monarch Initiative: MONDO:0004202

Definition

A carcinoma that arises from epithelial cells of the adrenal medulla [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  

Professional guidelines

PubMed

Endocrine tumors: the evolving role of positron emission tomography in diagnosis and management.
Naji M, Hodolic M, El-Refai S, Khan S, Marzola MC, Rubello D, Al-Nahhas A
J Endocrinol Invest 2010 Jan;33(1):54-60. Epub 2009 Oct 9 doi: 10.1007/BF03346550. PMID: 19820296
Treatment of metastatic disease in patients with neuroendocrine tumors.
Niederhuber JE, Fojo T
Surg Oncol Clin N Am 2006 Jul;15(3):511-33, viii. doi: 10.1016/j.soc.2006.05.004. PMID: 16882495
Adrenal incidentalomas: surgical treatment in 28 patients and update of the literature.
Porcaro AB, Novella G, Ficarra V, Curti P, Antoniolli SZ, Suangwoua HS, Malossini G
Int Urol Nephrol 2001;32(3):295-302. doi: 10.1023/a:1017587312369. PMID: 11583337

Recent clinical studies

Etiology

New Prognostic Indicators in Pediatric Adrenal Tumors: Neuroblastoma and Adrenal Cortical Tumors, Can We Predict When These Will Behave Badly?
Jarzembowski JA
Surg Pathol Clin 2020 Dec;13(4):625-641. Epub 2020 Oct 9 doi: 10.1016/j.path.2020.08.002. PMID: 33183724
Adrenal tumors: when to search for a germline abnormality?
Gimenez-Roqueplo AP
Curr Opin Oncol 2019 May;31(3):230-235. doi: 10.1097/CCO.0000000000000525. PMID: 30985498
Update on Adrenal Tumours in 2017 World Health Organization (WHO) of Endocrine Tumours.
Lam AK
Endocr Pathol 2017 Sep;28(3):213-227. doi: 10.1007/s12022-017-9484-5. PMID: 28477311
Adrenal Pathology in the Adult: A Urological Pathologist's Perspective.
Hansel DE, Reuter VE
Adv Anat Pathol 2016 Sep;23(5):273-84. doi: 10.1097/PAP.0000000000000120. PMID: 27438375
Rare adrenal tumors in children.
Mihai R
Semin Pediatr Surg 2014 Apr;23(2):71-5. Epub 2014 Mar 14 doi: 10.1053/j.sempedsurg.2014.03.004. PMID: 24931351

Diagnosis

Adrenal Neoplasms: Lessons from Adrenal Multidisciplinary Tumor Boards.
Chung R, Garratt J, Remer EM, Navin P, Blake MA, Taffel MT, Hackett CE, Sharbidre KG, Tu W, Low G, Bara M, Carney BW, Corwin MT, Campbell MJ, Lee JT, Lee CY, Dueber JC, Shehata MA, Caoili EM, Schieda N, Elsayes KM
Radiographics 2023 Jul;43(7):e220191. doi: 10.1148/rg.220191. PMID: 37347698
Adrenal tumors: when to search for a germline abnormality?
Gimenez-Roqueplo AP
Curr Opin Oncol 2019 May;31(3):230-235. doi: 10.1097/CCO.0000000000000525. PMID: 30985498
The human adrenal cortex: growth control and disorders.
Lotfi CFP, Kremer JL, Dos Santos Passaia B, Cavalcante IP
Clinics (Sao Paulo) 2018 Sep 6;73(suppl 1):e473s. doi: 10.6061/clinics/2018/e473s. PMID: 30208164Free PMC Article
Verner-Morrison syndrome. Literature review.
Belei OA, Heredea ER, Boeriu E, Marcovici TM, Cerbu S, Mărginean O, Iacob ER, Iacob D, Motoc AGM, Boia ES
Rom J Morphol Embryol 2017;58(2):371-376. PMID: 28730220
Rare adrenal tumors in children.
Mihai R
Semin Pediatr Surg 2014 Apr;23(2):71-5. Epub 2014 Mar 14 doi: 10.1053/j.sempedsurg.2014.03.004. PMID: 24931351

Therapy

Primary malignant tumors of the adrenal glands.
Almeida MQ, Bezerra-Neto JE, Mendonça BB, Latronico AC, Fragoso MCBV
Clinics (Sao Paulo) 2018 Dec 10;73(suppl 1):e756s. doi: 10.6061/clinics/2018/e756s. PMID: 30540124Free PMC Article
Robot-assisted adrenalectomy: indications and drawbacks.
Nomine-Criqui C, Germain A, Ayav A, Bresler L, Brunaud L
Updates Surg 2017 Jun;69(2):127-133. Epub 2017 May 12 doi: 10.1007/s13304-017-0448-6. PMID: 28497219
Lycium europaeum fruit extract: antiproliferative activity on A549 human lung carcinoma cells and PC12 rat adrenal medulla cancer cells and assessment of its cytotoxicity on cerebellum granule cells.
Ghali W, Vaudry D, Jouenne T, Marzouki MN
Nutr Cancer 2015;67(4):637-46. Epub 2015 Mar 31 doi: 10.1080/01635581.2015.1017054. PMID: 25825796
Rare adrenal tumors in children.
Mihai R
Semin Pediatr Surg 2014 Apr;23(2):71-5. Epub 2014 Mar 14 doi: 10.1053/j.sempedsurg.2014.03.004. PMID: 24931351
Treatment of metastatic disease in patients with neuroendocrine tumors.
Niederhuber JE, Fojo T
Surg Oncol Clin N Am 2006 Jul;15(3):511-33, viii. doi: 10.1016/j.soc.2006.05.004. PMID: 16882495

Prognosis

Primary malignant tumors of the adrenal glands.
Almeida MQ, Bezerra-Neto JE, Mendonça BB, Latronico AC, Fragoso MCBV
Clinics (Sao Paulo) 2018 Dec 10;73(suppl 1):e756s. doi: 10.6061/clinics/2018/e756s. PMID: 30540124Free PMC Article
The human adrenal cortex: growth control and disorders.
Lotfi CFP, Kremer JL, Dos Santos Passaia B, Cavalcante IP
Clinics (Sao Paulo) 2018 Sep 6;73(suppl 1):e473s. doi: 10.6061/clinics/2018/e473s. PMID: 30208164Free PMC Article
Update on Adrenal Tumours in 2017 World Health Organization (WHO) of Endocrine Tumours.
Lam AK
Endocr Pathol 2017 Sep;28(3):213-227. doi: 10.1007/s12022-017-9484-5. PMID: 28477311
Molecular targeted therapies in adrenal, pituitary and parathyroid malignancies.
Angelousi A, Dimitriadis GK, Zografos G, Nölting S, Kaltsas G, Grossman A
Endocr Relat Cancer 2017 Jun;24(6):R239-R259. Epub 2017 Apr 11 doi: 10.1530/ERC-16-0542. PMID: 28400402
Rare adrenal tumors in children.
Mihai R
Semin Pediatr Surg 2014 Apr;23(2):71-5. Epub 2014 Mar 14 doi: 10.1053/j.sempedsurg.2014.03.004. PMID: 24931351

Clinical prediction guides

Diagnostic, Prognostic, and Predictive Role of Ki67 Proliferative Index in Neuroendocrine and Endocrine Neoplasms: Past, Present, and Future.
La Rosa S
Endocr Pathol 2023 Mar;34(1):79-97. Epub 2023 Feb 17 doi: 10.1007/s12022-023-09755-3. PMID: 36797453Free PMC Article
Clinicopathological Evaluation of 15 Ectopic Adrenal Tissues.
Sensu S, Keser SH, Gurbuz Y, Barisik NO, Gul AE
Arch Iran Med 2021 Apr 1;24(4):301-305. doi: 10.34172/aim.2021.42. PMID: 34196190
New Prognostic Indicators in Pediatric Adrenal Tumors: Neuroblastoma and Adrenal Cortical Tumors, Can We Predict When These Will Behave Badly?
Jarzembowski JA
Surg Pathol Clin 2020 Dec;13(4):625-641. Epub 2020 Oct 9 doi: 10.1016/j.path.2020.08.002. PMID: 33183724
Update on Adrenal Tumours in 2017 World Health Organization (WHO) of Endocrine Tumours.
Lam AK
Endocr Pathol 2017 Sep;28(3):213-227. doi: 10.1007/s12022-017-9484-5. PMID: 28477311
Adrenal Pathology in the Adult: A Urological Pathologist's Perspective.
Hansel DE, Reuter VE
Adv Anat Pathol 2016 Sep;23(5):273-84. doi: 10.1097/PAP.0000000000000120. PMID: 27438375

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