U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Inferior vena cava obstruction

MedGen UID:
1053545
•Concept ID:
CN377013
•
Finding
HPO: HP:6000417

Definition

Physical invasion or compression of the inferior vena cava by a pathological process or by thrombosis within the vein itself. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInferior vena cava obstruction

Professional guidelines

PubMed

An update on management of Budd-Chiari syndrome.
Mancuso A
Ann Hepatol 2014 May-Jun;13(3):323-6. PMID: 24756006
Inferior vena cava obstruction: long-term results of endovascular management.
Srinivas BC, Dattatreya PV, Srinivasa KH, Prabhavathi, Manjunath CN
Indian Heart J 2012 Mar-Apr;64(2):162-9. Epub 2012 Apr 28 doi: 10.1016/S0019-4832(12)60054-6. PMID: 22572493Free PMC Article
Diagnosis and treatment of the inferior vena cava syndrome in advanced malignant disease.
Hartley JW, Awrich AE, Wong J, Stevens K, Fletcher WS
Am J Surg 1986 Jul;152(1):70-4. doi: 10.1016/0002-9610(86)90145-5. PMID: 3728821

Recent clinical studies

Etiology

Malignant obstruction of the inferior vena cava: clinical experience with the self-expanding Sinus-XL stent system.
Augustin AM, Lucius LJ, Thurner A, Kickuth R
Abdom Radiol (NY) 2022 Oct;47(10):3604-3614. Epub 2022 Jul 6 doi: 10.1007/s00261-022-03587-1. PMID: 35790568Free PMC Article
Systematic review of electrophysiology procedures in patients with obstruction of the inferior vena cava.
Al-Sinan A, Chan KH, Young GD, Martin A, Sepahpour A, Sy RW
J Cardiovasc Electrophysiol 2022 Jun;33(6):1300-1311. Epub 2022 Apr 30 doi: 10.1111/jce.15505. PMID: 35441755Free PMC Article
Histopathology of inferior vena cava obstruction in Budd-Chiari syndrome by clamp biopsy.
Bi Y, Zhu X, Yi M, Han X, Ren J
J Int Med Res 2020 Jul;48(7):300060520940438. doi: 10.1177/0300060520940438. PMID: 32706600Free PMC Article
Behcet's disease in Budd-Chiari syndrome.
Desbois AC, Rautou PE, Biard L, Belmatoug N, Wechsler B, Resche-Rigon M, Zarrouk V, Fantin B, de Chambrun MP, Cacoub P, Valla D, Saadoun D, Plessier A
Orphanet J Rare Dis 2014;9:104. Epub 2014 Sep 13 doi: 10.1186/s13023-014-0153-1. PMID: 25213625Free PMC Article
An update on management of Budd-Chiari syndrome.
Mancuso A
Ann Hepatol 2014 May-Jun;13(3):323-6. PMID: 24756006

Diagnosis

Evaluation of dangerous collateral vessels and thrombus in Budd-Chiari syndrome patients with inferior vena cava obstruction.
Liu D, Ren Q, Ye T, Zheng C, Su Y, Xia X
Abdom Radiol (NY) 2022 Feb;47(2):869-877. Epub 2021 Dec 9 doi: 10.1007/s00261-021-03354-8. PMID: 34888706
Histopathology of inferior vena cava obstruction in Budd-Chiari syndrome by clamp biopsy.
Bi Y, Zhu X, Yi M, Han X, Ren J
J Int Med Res 2020 Jul;48(7):300060520940438. doi: 10.1177/0300060520940438. PMID: 32706600Free PMC Article
Inferior vena cava obstruction in Budd-Chiari syndrome: a comparative study of rapid quantitative phase-contrast MRI and MRV.
Lu X, Ma X, Xu K, Wang J, Yang C
Abdom Radiol (NY) 2020 Apr;45(4):1069-1074. doi: 10.1007/s00261-019-02394-5. PMID: 32055901
Magnetic resonance venography in the diagnosis of inferior vena cava obstruction in Budd-Chiari syndrome.
Lu X, Yang C, Xu K, Rong YT, Li SD, Li JS, Hu CF, Song Q, Ma P, Zhang QQ, Xu H, Zu MH
Eur Rev Med Pharmacol Sci 2015;19(2):256-64. PMID: 25683939
Inferior vena cava obstruction: long-term results of endovascular management.
Srinivas BC, Dattatreya PV, Srinivasa KH, Prabhavathi, Manjunath CN
Indian Heart J 2012 Mar-Apr;64(2):162-9. Epub 2012 Apr 28 doi: 10.1016/S0019-4832(12)60054-6. PMID: 22572493Free PMC Article

Therapy

Inferior Vena Cava Obstruction Complicating Remote Venovenous Extracorporeal Membrane Oxygenation Bridge to Lung Transplantation.
Coston TD, Vaidya S, Badulak J, Garcia D, Keel S, Mulligan M, Ramos KJ, Kapnadak SG
Chest 2022 Jul;162(1):e5-e8. doi: 10.1016/j.chest.2022.01.062. PMID: 35809951
Malignant obstruction of the inferior vena cava: clinical experience with the self-expanding Sinus-XL stent system.
Augustin AM, Lucius LJ, Thurner A, Kickuth R
Abdom Radiol (NY) 2022 Oct;47(10):3604-3614. Epub 2022 Jul 6 doi: 10.1007/s00261-022-03587-1. PMID: 35790568Free PMC Article
An update on management of Budd-Chiari syndrome.
Mancuso A
Ann Hepatol 2014 May-Jun;13(3):323-6. PMID: 24756006
Inferior vena cava obstruction and collateral circulation as unusual manifestations of hepatobiliary cystadenocarcinoma.
Arkadopoulos N, Yiallourou AI, Palialexis C, Stamatakis E, Kairi-Vassilatou E, Smyrniotis V
Hepatobiliary Pancreat Dis Int 2013 Jun;12(3):329-31. doi: 10.1016/s1499-3872(13)60052-1. PMID: 23742780
Epidural venous plexus enlargements presenting with radiculopathy and back pain in patients with inferior vena cava obstruction or occlusion.
Paksoy Y, Gormus N
Spine (Phila Pa 1976) 2004 Nov 1;29(21):2419-24. doi: 10.1097/01.brs.0000144354.36449.2f. PMID: 15507805

Prognosis

Magnetic resonance venography in the diagnosis of inferior vena cava obstruction in Budd-Chiari syndrome.
Lu X, Yang C, Xu K, Rong YT, Li SD, Li JS, Hu CF, Song Q, Ma P, Zhang QQ, Xu H, Zu MH
Eur Rev Med Pharmacol Sci 2015;19(2):256-64. PMID: 25683939
Inferior vena cava obstruction and collateral circulation as unusual manifestations of hepatobiliary cystadenocarcinoma.
Arkadopoulos N, Yiallourou AI, Palialexis C, Stamatakis E, Kairi-Vassilatou E, Smyrniotis V
Hepatobiliary Pancreat Dis Int 2013 Jun;12(3):329-31. doi: 10.1016/s1499-3872(13)60052-1. PMID: 23742780
The management of inferior vena cava obstruction complicating metastatic germ cell tumors.
Hassan B, Tung K, Weeks R, Mead GM
Cancer 1999 Feb 15;85(4):912-8. PMID: 10091770
Diagnosis and treatment of the inferior vena cava syndrome in advanced malignant disease.
Hartley JW, Awrich AE, Wong J, Stevens K, Fletcher WS
Am J Surg 1986 Jul;152(1):70-4. doi: 10.1016/0002-9610(86)90145-5. PMID: 3728821
INFERIOR VENA CAVA OBSTRUCTION: CLINICAL MANIFESTATIONS, DIAGNOSTIC METHODS, AND RELATED PROBLEMS.
MISSAL ME, ROBINSON JA, TATUM RW
Ann Intern Med 1965 Jan;62:133-61. doi: 10.7326/0003-4819-62-1-133. PMID: 14258342

Clinical prediction guides

Systematic review of electrophysiology procedures in patients with obstruction of the inferior vena cava.
Al-Sinan A, Chan KH, Young GD, Martin A, Sepahpour A, Sy RW
J Cardiovasc Electrophysiol 2022 Jun;33(6):1300-1311. Epub 2022 Apr 30 doi: 10.1111/jce.15505. PMID: 35441755Free PMC Article
Detection and characterization of Budd-Chiari syndrome with inferior vena cava obstruction: Comparison of fixed and flexible delayed scan time of computed tomography venography.
Zhou PL, Wu G, Han XW, Bi YH, Zhang WG, Wu ZY
Eur J Radiol 2017 Jun;91:52-56. Epub 2017 Mar 29 doi: 10.1016/j.ejrad.2017.03.021. PMID: 28629571
Magnetic resonance venography in the diagnosis of inferior vena cava obstruction in Budd-Chiari syndrome.
Lu X, Yang C, Xu K, Rong YT, Li SD, Li JS, Hu CF, Song Q, Ma P, Zhang QQ, Xu H, Zu MH
Eur Rev Med Pharmacol Sci 2015;19(2):256-64. PMID: 25683939
Inferior vena cava obstruction and collateral circulation as unusual manifestations of hepatobiliary cystadenocarcinoma.
Arkadopoulos N, Yiallourou AI, Palialexis C, Stamatakis E, Kairi-Vassilatou E, Smyrniotis V
Hepatobiliary Pancreat Dis Int 2013 Jun;12(3):329-31. doi: 10.1016/s1499-3872(13)60052-1. PMID: 23742780
Epidural venous plexus enlargements presenting with radiculopathy and back pain in patients with inferior vena cava obstruction or occlusion.
Paksoy Y, Gormus N
Spine (Phila Pa 1976) 2004 Nov 1;29(21):2419-24. doi: 10.1097/01.brs.0000144354.36449.2f. PMID: 15507805

Recent systematic reviews

Systematic review of electrophysiology procedures in patients with obstruction of the inferior vena cava.
Al-Sinan A, Chan KH, Young GD, Martin A, Sepahpour A, Sy RW
J Cardiovasc Electrophysiol 2022 Jun;33(6):1300-1311. Epub 2022 Apr 30 doi: 10.1111/jce.15505. PMID: 35441755Free PMC Article
Prevalence and risk factors of hepatocellular carcinoma in Budd-Chiari syndrome: a systematic review.
Ren W, Qi X, Yang Z, Han G, Fan D
Eur J Gastroenterol Hepatol 2013 Jul;25(7):830-41. doi: 10.1097/MEG.0b013e32835eb8d4. PMID: 23411869

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...